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Swept source oct

Elena Garcia-Martin, Laura Jarauta, Elisa Vilades, Jose Ramon Ara, Jesus Martin, Vicente Polo, Jose Manuel Larrosa, Luis Emilio Pablo, Maria Satue
Purpose: To evaluate the ability of new swept-source (SS) optical coherence tomography (OCT) technology to detect changes in retinal and choroidal thickness in patients with multiple sclerosis (MS). Methods: A total of 101 healthy and 97 MS eyes underwent retinal and choroidal assessment using SS Triton OCT (Topcon). Macular thickness and peripapillary data (retinal, ganglion cell layer (GCL+, GCL++) and retinal nerve fiber layer (RNFL) thickness) were analyzed, including choroidal thickness evaluation...
2018: Journal of Ophthalmology
Meng Tian, Christoph Tappeiner, Martin S Zinkernagel, Wolfgang Huf, Sebastian Wolf, Marion R Munk
PURPOSE: To evaluate vascular changes in patients with intermediate uveitis with or without retinal vasculitis using swept-source wide-field optical coherence tomography angiography (OCTA). METHODS: This is a prospective cross-sectional study. Consecutive patients with intermediate uveitis were evaluated using wide-field OCTA. Wide-field OCTA and en-face OCT images were analysed for the presence of capillary non-perfusion and reduced perfusion, disruption of ellipsoid zone, and abnormalities on en-face wide-field retinal thickness maps, respectively, and compared with fluorescein angiography (FA) findings in a subcohort...
December 11, 2018: British Journal of Ophthalmology
Lavinia Ferrante di Ruffano, Jacqueline Dinnes, Jonathan J Deeks, Naomi Chuchu, Susan E Bayliss, Clare Davenport, Yemisi Takwoingi, Kathie Godfrey, Colette O'Sullivan, Rubeta N Matin, Hamid Tehrani, Hywel C Williams
BACKGROUND: Early accurate detection of all skin cancer types is essential to guide appropriate management and to improve morbidity and survival. Melanoma and squamous cell carcinoma (SCC) are high-risk skin cancers, which have the potential to metastasise and ultimately lead to death, whereas basal cell carcinoma (BCC) is usually localised, with potential to infiltrate and damage surrounding tissue. Anxiety around missing early cases needs to be balanced against inappropriate referral and unnecessary excision of benign lesions...
December 3, 2018: Cochrane Database of Systematic Reviews
Susumu Sakimoto, Tomoyuki Okazaki, Shinichi Usui, Tomoyuki Ishibashi, Yoshihito Oura, Kentaro Nishida, Atsuya Miki, Ryo Kawasaki, Kenji Matsushita, Hirokazu Sakaguchi, Kohji Nishida
Purpose: To determine the relevance of epiretinal membranes (ERMs) in primary open-angle glaucoma (POAG) and potential risk for glaucoma severity. Methods: Sixty eyes of 30 patients with POAG who had a unilateral ERM were analyzed; 60 nonglaucomatous eyes of 30 patients with a unilateral ERM also were recruited in this institutional cross-sectional study. Patients underwent swept-source (SS) optical coherence tomography (OCT) imaging and visual field testing. Intraindividual differences in the SS-OCT retinal nerve fiber layer (RNFL) disc cupping area measurements and visual field outcomes were analyzed in the two groups...
December 3, 2018: Investigative Ophthalmology & Visual Science
Diego Vezzola, Davide Allegrini, Alfredo Borgia, Paolo Fogagnolo, Luca Mario Rossetti, Mario R Romano, Stefano De Cillà
PURPOSE: To describe swept-source optical coherence tomography and optical coherence tomography angiography retinal changes in a case of acute toxoplasmic chorioretinitis both at the time of diagnosis and after healing. CASE PRESENTATION: A 57-year-old white woman suffering from acquired toxoplasmic chorioretinitis underwent swept-source optical coherence tomography and optical coherence tomography angiography both at the time of diagnosis and after healing. In the acute phase of the disease, swept-source optical coherence tomography clearly showed retinal and choroidal involvement in the superficial retina and in the choroidal swelling...
December 4, 2018: Journal of Medical Case Reports
Arif Ülkü Yener, Osman Korucu
The aim of the study was to measure the thicknesses of the inner retinal segments and optic nerve head (ONH) parameters in migraineurs and patients with tension-type headache (TTH) in headache-free period using swept source optical coherence tomography (SS-OCT) and to compare the outcomes with each other and those of healthy subjects. The study population consisted of 23 migraineurs, 22 TTH patients, and 25 controls with a best-corrected visual acuity of 20/20 and without a history of systemic or ocular disease...
November 30, 2018: Acta Neurologica Belgica
George J Manayath, Sidharth Narendran
No abstract text is available yet for this article.
September 2018: Oman Journal of Ophthalmology
Isaac W Chay, Louis W Lim, Kai Xiong Cheong, Colin S Tan
No abstract text is available yet for this article.
September 2018: Oman Journal of Ophthalmology
Kenneth P Johnson, Aisha McLean, Gary S Rubin, Vasilios P Papastefanou, Aadil Hussain, Yijun Cai, Mandeep S Sagoo, M Ashwin Reddy
No abstract text is available yet for this article.
November 28, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Natalia Porporato, Mani Baskaran, Tin A Tun, Rehena Sultana, Marcus Cl Tan, Joanne Hm Quah, John Allen, David S Friedman, Ching-Yu Cheng, Tin Aung
PURPOSE: To evaluate the diagnostic performance of swept-source optical coherence tomography (SS-OCT, CASIA SS-1000, Tomey Corporation, Nagoya, Japan) for angle closure detection, in comparison with gonioscopy in a community setting. DESIGN: Reliability analysis. METHODS: A total of 2027 phakic subjects aged ≥50 years, with no previous history of glaucoma, laser (including peripheral iridotomy), intraocular surgery or ocular trauma, were consecutively recruited from a community polyclinic in Singapore...
November 28, 2018: American Journal of Ophthalmology
Sumit Randhir Singh, Kiran Kumar Vupparaboina, Abhilash Goud, Kunal K Dansingani, Jay Chhablani
The choroid is the vascular coat of the eye,and its role has been studied in multiple chorioretinal disorders. The recent advancements in choroidal imaging techniques including enhanced depth imaging optical coherence tomography (EDI-OCT), swept source (SS-OCT), enface OCT and OCT angiography have facilitated an in-depth analysis of choroid. The gradual shift from manual to automated segmentation and binarization methods have led to precise and reproducible measurements of choroidal parameters. These qualitative and quantitative parameters, called choroidal imaging biomarkers, have evolved over the past decade from a simple linear subfoveal choroidal thickness to more complex 3 dimensional (3-D) choroidal reconstruction thus widening the spectrum encompassing multiple parameters...
November 26, 2018: Survey of Ophthalmology
Yui Kobayashi, Shunsuke Nakakura, Etsuko Terao, Yuki Fujio, Kanae Matsuya, Hitoshi Tabuchi, Yasuhiro Takahashi, Yoshiaki Kiuchi
Purpose: To investigate iris morphological features in 360° angle-closure neovascular glaucoma (NVG) by swept-source anterior segment optical coherence tomography (ASOCT). Patients and Methods: In this retrospective, clinic-based, comparative study, 14 patients with 360° angle-closure NVG and 14 healthy age-matched control subjects were enrolled. All patients enrolled had no prior glaucoma surgery but underwent cataract surgery with intraocular lens implantation...
September 2018: Case Reports in Ophthalmology
Yukinori Sugano, Tetsuju Sekiryu, Minoru Furuta, Ryutaro Tomita, Hiroaki Shintake, Hiroki Maehara, Akira Ojima
Purpose: To assess the reproducibility of quantitative morphometrical evaluation of the choriocapillaris imaged with swept-source optical coherence tomography angiography (SS-OCTA). Subjects and methods: This observational, cross-sectional case series included 35 eyes of healthy individuals and 32 eyes of 32 patients. Two images of the fovea were taken using SS-OCTA with 3×3 mm squares. Images of the choriocapillaris within 800×800 pixel squares centered at the fovea were analyzed morphometrically using open-source software "AngioTool" that applies a Gaussian recursive filter and multiscale Hessian enhancement...
2018: Clinical Ophthalmology
Samuel F Passi, Atalie C Thompson, Preeya K Gupta
Purpose: To compare the agreement and efficiency of a swept source-optical coherence tomography biometer, IOLMaster 700 (IOLM700), and a low-coherence optical reflectometry biometer, LENSTAR LS 900 (LS900), when acquiring biometry measurements during cataract evaluation. Methods: A retrospective chart review of biometry measurements that were performed in 64 eyes of 32 patients on the same day using the LS900 and the IOLM700. The total image acquisition time per subject was compared between the two machines using a Wilcoxon rank-sum test...
2018: Clinical Ophthalmology
Yong Un Shin, Dong Eik Lee, Min Ho Kang, Mincheol Seong, Joo-Hark Yi, Sang-Woong Han, Heeyoon Cho
The purpose of this study is to evaluate the effect of haemodialysis on perfused vessel density, choroidal thickness (CT), and retinal thickness in end-stage renal disease (ESRD) using swept-source optical coherence tomography angiography (SS-OCTA). We studied twenty-nine eyes of 29 ESRD patients by ophthalmologic examination and SS-OCTA before and after haemodialysis. The colour-coded perfusion density maps were generated and perfused vessel density was calculated. Changes in systemic and other ocular parameters such as retinal and choroidal thickness were measured and analysed...
November 21, 2018: Scientific Reports
Kazuko Omodaka, Shigeto Maekawa, Guangzhou An, Satoru Tsuda, Yukihiro Shiga, Naoko Takada, Tsutomu Kikawa, Hidetoshi Takahashi, Hideo Yokota, Masahiro Akiba, Toru Nakazawa
PURPOSE: To develop a method to quantify, based on swept-source optical coherence tomography (OCT), the 3D structure of the laminar pores in patients with glaucoma. METHODS: This retrospective study examined 160 laminar pores from 8 eyes of 8 cases: 4 normal subjects and 4 open-angle glaucoma (OAG) patients. We reconstructed 3D volume data for a 3 x 3 mm disc, using a method similar to OCT angiography, and segmented the structure of the lamina cribrosa. Then, we manually segmented each laminar pore in sequential C-scan images (>90 slices at 2...
2018: PloS One
Sucbei Moon, Zhongping Chen
Phase-resolved imaging of swept-source optical coherence tomography (SS-OCT) is subject to phase measurement instabilities involved with the sweep variation of a frequency-swept source. In general, optically generated timing references are utilized to track the variations imposed on OCT signals. But they might not be accurately synchronized due to relative time delays. In this research, we investigated the impact of the signal delays on the timing instabilities and the consequent deviations of the measured phases...
November 1, 2018: Biomedical Optics Express
Elie H Motulsky, Fang Zheng, Yingying Shi, Giovanni Gregori, Philip J Rosenfeld
BACKGROUND AND OBJECTIVE: Swept-source optical coherence tomography angiography (SS-OCTA) and different boundary-specific segmentation strategies were used to distinguish type 1 macular neovascularization (MNV) from type 2 MNV in eyes with exudative age-related macular degeneration (AMD). PATIENTS AND METHODS: Eyes with exudative AMD were enrolled in a prospective study. Segmentation strategies included a slab from the outer retina (OR) to the choriocapillaris (CC) for the entire MNV, a slab from the retinal pigment epithelium (RPE) to the CC for the type 1 MNV, and a slab from the OR to the RPE for the type 2 MNV...
November 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Shangjun Jiang, Netan Choudhry
BACKGROUND AND OBJECTIVE: To gain insight into clinical presentations associated with anomalous foveal avascular zone (FAZ) architecture and foveal pit morphology. PATIENTS AND METHODS: Twenty-two eyes with anomalous (vascularized) FAZs were identified from 14 patients using optical coherence tomography angiography (OCTA). The FAZ was evaluated in three vascular layers of the retina: the superficial capillary plexus (SCP), the deep capillary plexus (DCP), and the degree of foveal pit hypoplasia was graded...
November 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Rajan Gupta, Rajeev R Pappuru, Vivek P Dave, Jay Chhablani
Combined hamartoma of retina and retinal pigment epithelium (CHRRPE) has been considered as a congenital benign entity with evidence of choroidal neovascularization membranes (CNVM) being associated with it in literature. This case series gives insight into the pathogenesis and the predisposing factors leading to CNVM formation in peripapillary CHRRPE using swept-source optical coherence tomography. In addition, lack of typical markers of CNVM (subretinal fluid/pigment epithelial detachment) in CHRRPE highlights the utility of optical coherence tomography angiography and the subtle optical coherence tomography findings such as "Bridge Sign" that could be instrumental in early diagnosis of CNVM in CHRRPE...
December 2018: Indian Journal of Ophthalmology
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