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Swept source oct

Enrico Borrelli, Yue Shi, Akihito Uji, Siva Balasubramanian, Marco Nassisi, David Sarraf, SriniVas R Sadda
OBJECTIVE: To quantitate regional differences in the choriocapillaris (CC) of patients with intermediate age-related macular degeneration (iAMD), using swept source-optical coherence tomography angiography (SS-OCTA) imaging. SETTING: Cross sectional study. METHODS: Subjects were imaged with the SS-OCTA system (PLEX Elite 9000, Carl Zeiss Meditec Inc., Dublin, CA, USA). The CC en face images were first compensated for the signal attenuation caused by drusen by using the structural information from the same slab...
August 14, 2018: American Journal of Ophthalmology
Cerine Lal, Hrebesh M Subhash, Sergey Alexandrov, Martin J Leahy
Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and functional parameters such as oxygen saturation. In this study, we present a modified scanning-based correlation mapping OCT using a 200 kHz high-speed swept-source OCT system operating at 1300 nm and demonstrate its wide field-imaging capability in ocular angiographic studies.
August 1, 2018: Applied Optics
David Tes, Ahmed Aber, Mohsin Zafar, Luke Horton, Audrey Fotouhi, Qiuyun Xu, Ali Moiin, Andrew D Thompson, Tatiana Cristina Moraes Pinto Blumetti, Steven Daveluy, Wei Chen, Mohammadreza Nasiriavanaki
Background: Granular cell tumor (GCT) is a relatively uncommon tumor that may affect the skin. The tumor can develop anywhere on the body, although it is predominately seen in oral cavities and in the head and neck regions. Here, we present the results of optical coherence tomography (OCT) imaging of a large GCT located on the abdomen of a patient. We also present an analytical method to differentiate between healthy tissue and GCT tissues. Materials and methods: A multibeam, Fourier domain, swept source OCT was used for imaging...
2018: Biomedical Engineering and Computational Biology
Hendrik Spahr, Clara Pfäffle, Peter Koch, Helge Sudkamp, Gereon Hüttmann, Dierck Hillmann
Doppler optical coherence tomography (OCT) quantifies axial motion with high precision, whereas lateral motion cannot be detected by a mere evaluation of phase changes. This problem was solved by the introduction of three-beam Doppler OCT, which, however, entails a high experimental effort. Here, we present the numerical analogue to this experimental approach. Phase-stable complex-valued OCT datasets, recorded with full-field swept-source OCT, are filtered in the Fourier domain to limit imaging to different computational subapertures...
July 23, 2018: Optics Express
Nhan M Le, Shaozhen Song, Hao Zhou, Jingjiang Xu, Yuandong Li, Cheng-En Sung, Alireza Sadr, Kwok-Hung Chung, Hrebesh M Subhash, Latonya Kilpatrick, Ruikang K Wang
Gingiva is the soft tissue that surrounds and protects the teeth. Healthy gingiva provides an effective barrier to periodontal insults to deeper tissue, thus is an important indicator to a patient's periodontal health. Current methods in assessing gingival tissue health, including visual observation and physical examination with probing on the gingiva, are qualitative and subjective. They may become cumbersome when more complex cases are involved, such as variations in gingival biotypes where feature and thickness of the gingiva are considered...
August 15, 2018: Journal of Biophotonics
Claudio Furino, Luca Di Antonio, Maria Oliva Grassi, Marco Rispoli, Michele Reibaldi, Alfredo Niro, Giovanni Alessio
PURPOSE: To evaluate the response to anti-vascular endothelial growth factor therapy for choroidal neovascularization secondary to choroidal osteoma using optical coherence tomography angiography. METHODS: This retrospective study included four eyes of four females with choroidal osteoma complicated by choroidal neovascularization, treated with ranibizumab. All patients underwent full ophthalmologic examination, including ocular ultrasound, retinography, fluorescein angiography, spectral-domain or swept-source optical coherence tomography, and optical coherence tomography angiography...
August 13, 2018: European Journal of Ophthalmology
Tadamichi Akagi, Akihito Uji, Alex S Huang, Robert N Weinreb, Tatsuya Yamada, Manabu Miyata, Takanori Kameda, Hanako Ohashi Ikeda, Akitaka Tsujikawa
PURPOSE: To investigate conjunctival and intrascleral vasculatures using anterior-segment (AS) optical coherence tomography angiography (OCTA) in normal eyes. DESIGN: Cross-sectional study. METHODS: AS-OCTA images of the corneal limbus were acquired circumferentially using a swept-source OCT system in 10 eyes of 10 healthy subjects. AS-OCTA flow patterns with en face maximum projection were compared between the superficial (from the conjunctival epithelium to a depth of 200 μm) and deep (from a depth of 200 μm to 1000 μm) layers...
August 9, 2018: American Journal of Ophthalmology
Manabu Miyata, Akio Oishi, Akitaka Tsujikawa
No abstract text is available yet for this article.
August 1, 2018: JAMA Ophthalmology
Bayan Rashed, Yoshiko Iino, Kei Komatsu, Miki Nishijo, Takahiro Hanada, Arata Ebihara, Mitsuhiro Sunakawa, Yasunori Sumi, Takashi Okiji
OBJECTIVE: This study aimed to evaluate the ability of swept-source optical coherence tomography (OCT) to detect internal anatomy of maxillary premolars in comparison with dental operating microscope (DOM) and cone beam computed tomography (CBCT). BACKGROUND DATA: The ability of OCT to observe the pulp horn during cavity preparation and assess the remaining dentin thickness (RDT) has been demonstrated, whereas validation of OCT in comparison with other imaging techniques seems required...
August 10, 2018: Photomedicine and Laser Surgery
Fupeng Wang, Qinqin Zhang, Anthony J Deegan, Jun Chang, Ruikang K Wang
Background: There are two forms of system implementation of optical coherence tomography angiography (OCTA) in ophthalmic imaging, i.e., spectral domain (SD-) and swept source OCTA (SS-OCTA). The purpose of this paper is to compare the SD-OCTA and SS-OCTA for elucidating structural and vascular features associated with central serous retinopathy (CSR), and to evaluate the effects of CSR on SD- and SS-OCTA's imaging capabilities. Methods: Normal subjects and CSR patients were imaged by SD- and SS-OCTA using 3 × 3 mm and 6 × 6 mm scan patterns...
2018: Eye and Vision (London, England)
Sang Yeop Lee, Hyoung Won Bae, Gong Je Seong, Chan Yun Kim
PURPOSE: To compare the diagnostic abilities of swept-source optical coherence tomography (OCT) [Deep Range Imaging OCT-1 (DRI-OCT)] and spectral-domain OCT (Cirrus HD-OCT) for glaucoma in Korean adults. MATERIALS AND METHODS: This retrospective study involved measuring peripapillary retinal nerve fiber layer (PP-RNFL) thickness, full macular thickness, and ganglion cell-inner plexiform layer (GC-IPL) thickness on two different OCT systems. We used three-dimensional optic disc scanning of DRI-OCT and included 12 clock-hour sectors for measurement of the PP-RNFL...
September 2018: Yonsei Medical Journal
Young Joo Cho, Tae Hyung Lim, Kee Yong Choi, Beom Jin Cho
PURPOSE: To evaluate the agreement between optical biometry with swept-source optical coherence tomography-based optical biometry (IOLMaster 700) and other devices. METHODS: A total of 137 eyes (78 patients) with cataracts were included in this retrospective study. Axial length (AL), anterior chamber depth (ACD), keratometry, and white-to-white (WTW) distance measured using IOLMaster 700 were compared with results for the following five different biometers: IOLMaster 500, A-scan, automated refractor, manual keratometry, and Galilei G4...
August 2018: Korean Journal of Ophthalmology: KJO
Grace Tsai, Touka Banaee, Felipe F Conti, Rishi P Singh
Optical coherence angiography (OCTA) is a noninvasive technique that has been introduced in recent years to detect ophthalmological pathology. The growing usage of OCTA to detect retinal abnormalities can be attributed to its advantages over the reference-standard fluorescein angiography (FA), although both of these techniques can be used in association. OCTA's advantages include its dye independency, its ability to produce depth-resolved images of retinal and choroidal vessels that yield images of different vascular layers of the retina, and the better delineation of the foveal avascular zone...
July 2018: Journal of Ophthalmic & Vision Research
Tadamichi Akagi, Linda M Zangwill, Takuhei Shoji, Min Hee Suh, Luke J Saunders, Adeleh Yarmohammadi, Patricia Isabel C Manalastas, Rafaella C Penteado, Robert N Weinreb
PURPOSE: To evaluate microvasculature dropout in the optic disc (Mvd-D) using optical coherence tomography angiography (OCTA) and investigate factors associated with Mvd-D in primary open-angle glaucoma (POAG) eyes. METHODS: One hundred twenty-three eyes of 123 POAG patients were included from the Diagnostic Innovations in Glaucoma Study. The 3.0×3.0-mm optic nerve head OCTA scans were acquired using a spectral-domain OCT instrument. Images with whole-signal-mode were evaluated...
2018: PloS One
Richard I Kaplan, Joseph B Walsh, Richard B Rosen, Meenakashi Gupta
PURPOSE: To report a case of macular vortex vein imaged with indocyanine green angiography, spectral domain optical coherence tomography, and optical coherence tomography angiography. METHODS: Observational case report. RESULTS: A 51-year-old myopic man presented with the complaint of a floater in his left eye for the previous 2 weeks. His visual acuity was 20/25 in the right eye and 20/40 in the left eye. Biomicroscopy was normal. Retinoscopy revealed lattice degeneration and posterior vitreous detachment of both eyes with dilated submacular vasculature in the right eye and submacular hemorrhage in the left eye...
August 6, 2018: Retinal Cases & Brief Reports
Haoyu Wang, Shi Zhuan Tan, Tariq Aslam, Nicholas P Jones, Laura R Steeples
PURPOSE: To evaluate multimodal imaging findings in longitudinal follow-up of a patient with presumed tuberculous serpiginous-like choroiditis (TB-SLC). METHOD: We evaluated multimodal imaging in a 62-year-old male with TB-SLC. Correlation between optical coherence tomography angiography (OCTA), swept-source OCT (SS-OCT) and fundus autofluorescence (FAF) at defined disease stages and evolution of observed imaging descriptors during long-term follow-up has not been previously reported...
August 6, 2018: Ocular Immunology and Inflammation
L de-Pablo-Gómez-de-Liaño, I Cañas Zamarra, J I Fernández-Vigo, M Fernández Vidal, C Navarro-Perea, T Cavero Escribano
Complement-mediated membranoproliferative glomerulonephritis is a rare progressive glomerular disease. In some patients it can be associated with retinal lesions. Therefore, the purpose of this study was to assess a case series with this diagnosis in our hospital. A cross-sectional study was conducted on 8 patients diagnosed with complement-mediated membranoproliferative glomerulonephritis. Funduscopy, optical coherence tomography (OCT) and Swept Source domain OCT angiography were performed. Only 1 of the 8 patients showed drusen-like deposits that were located under the retinal pigment epithelium in the OCT, with the presence of associated choroidal neovascularization being ruled out in OCT angiography...
August 2, 2018: Archivos de la Sociedad Española de Oftalmología
Hamed Esfandiari, Mohammad Pakravan, Nassim Amouhashemi, Mehdi Yaseri, Pooya Torkian, Khosrow Jadidi, Nils A Loewen
PURPOSE: To evaluate the association between baseline ocular variables and the widening of the anterior chamber angle by laser peripheral iridotomy (LPI) in primary angle closure suspects (PACS) using a new Fourier-domain swept-source anterior segment optical coherence tomography (FD-ASOCT). METHOD: Sixty-six PACS eyes of 41 individuals were enrolled in this prospective interventional case series. An FD-ASOCT (Casia SS-1000 OCT; Tomey, Nagoya, Japan) was used to measure biometric baseline variables and at 1 month after the LPI...
August 2, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Kwan Seob Park, Jun Geun Shin, Muhammad Mohsin Qureshi, Euiheon Chung, Tae Joong Eom
The hippocampus is associated with memory and navigation, and the rodent hippocampus provides a useful model system for studying neurophysiology such as neural plasticity. Vascular changes at this site are closely related to brain diseases, such as Alzheimer's disease, dementia, and epilepsy. Vascular imaging around the hippocampus in mice may help to further elucidate the mechanisms underlying these diseases. Optical coherence tomography angiography (OCTA) is an emerging technology that can provide label-free blood flow information...
August 2, 2018: Scientific Reports
Jyothsna Konkada Manattayil, Naresh Kumar Ravichandran, Ruchire Eranga Wijesinghe, Muhammad Faizan Shirazi, Seung-Yeol Lee, Pilun Kim, Hee-Young Jung, Mansik Jeon, Jeehyun Kim
The non-destructive classification of plant materials using optical inspection techniques has been gaining much recent attention in the field of agriculture research. Among them, a near-infrared (NIR) imaging method called optical coherence tomography (OCT) has become a well-known agricultural inspection tool since the last decade. Here we investigated the non-destructive identification capability of OCT to classify diversely stained (with various staining agents) Capsicum annuum seed specimens of different cultivars...
August 1, 2018: Sensors
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