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Accelerated Orthodontics

Mohammad Moslem Imani, Amin Golshah, Roya Safari-Faramani, Masoud Sadeghi
Background: Low-level Laser Therapy (LLLT) is a noninvasive method of accelerating tooth movement. Herein, this meta-analysis was aimed to assess the efficacy of LLLT in accelerating orthodontic tooth movement of human maxilla or mandible canine. Methods: Five databases including Web of Science, Scopus, PubMed, ScienceDirect, and Cochrane Library were used for searching the studies. Studies on LLLT for orthodontic tooth movement of human canine, randomized clinical trial (RCT), and outcome variables such as distance or speed of the tooth movement in treatment duration were considered for the final analysis...
June 2018: Acta Informatica Medica: AIM
Soraia Macari, Mila F M Madeira, Izabella L A Lima, Thaís S F Pereira, George J Dias, Joni A Cirelli, Rafael S de Molon, Sandra Y Fukada, Raphael E Szawka, Gustavo P Garlet, Mauro M Teixeira, Tarcília A Silva
Interleukin-33 (IL-33) and its receptor, ST2, are implicated in bone remodeling. The lack of estrogen after menopause results in an accelerated bone loss. Here we investigated the role of ST2 in the bone loss induced by estrogen deficiency. ST2-deficient mice (ST2-/- ) and their littermates (wildtype [WT]) were ovariectomized (OVX), while ovary-intact mice were used as controls. Bone sites were analyzed by microcomputed tomography, histomorphometry, and quantitative real-time polymerase chain reaction (qPCR)...
July 16, 2018: Journal of Cellular Biochemistry
Li-Fang Hsu, Meng-Huan Tsai, Athena Hsuan-Yu Shih, Yang-Cheng Chen, Bei-En Chang, Yi-Jane Chen, Chung-Chen Jane Yao
OBJECTIVE: During orthodontic tooth movement (OTM), the speed of movement depends on the rate of bone turnover. In this study, we used a rat model to investigate the effect of 970 nm low-level laser therapy (LLLT) on OTM under different dose and frequency protocols. METHODS: We first compared the OTM rates between the OTM only control and the OTM + LLLT group (1250 J/cm2 ) in Experiment 1 and showed that LLLT significantly increased OTM. In Experiment 2, we employed 3 different LLLT protocols: the low-dose group and the high-dose group receiving 5 doses of 750 J/cm2 and 15,000 J/cm2 of LLLT every 3 days, respectively, and the early high-dose group which received 5 daily doses at 15,000 J/cm2 at the beginning of the experiments...
July 10, 2018: Journal of Photochemistry and Photobiology. B, Biology
Thomas S Shipley
Evaluation of the effect of a high frequency acceleration device (HFA) on clear aligner exchange intervals and treatment time required to achieve prescribed tooth movements. Sixteen subjects with similar Class I malocclusions, ≤5 mm crowding, and treated with aligner orthodontic therapy (Invisalign) were divided into two groups. Group 1 (experimental; n = 8) underwent aligner treatment in conjunction with daily use of the HFA device and exchanged aligners every five days. Group 2 (controls; n = 8) underwent aligner treatment without use of the device and exchanged aligners every 14 days according to the manufacturer's recommended interval...
July 12, 2018: Dentistry journal
Snigdha Pattanaik, Navya Puvvula, Noorjahan Mohammad
Background: Patients with class II malocclusion generally seek orthodontic treatment for esthetic concern. Various myo-functionl appliances can be used for the treatment of skeletal as well as the dental malocclusion in a growing patient. Among various functional appliances, twin block appliance is most commonly used due to better patient compliances. It redirects the mandibular growth to correct the maxillomandibular relationship, enhancing facial esthet ics. This article presents a modified design of the twin block appliance which is less bulky, more esthetic, can be used concurrently with fixed orthodontic appliance, and is easily accepted by uncooperative patients...
March 2018: International Journal of Clinical Pediatric Dentistry
Shiva Safari, Arezoo Mahdian, Saeed Reza Motamedian
A simple overview of daily orthodontic practice involves use of brackets, wires and elastomeric modules. However, investigating the underlying effect of orthodontic forces shows various molecular and cellular changes. Also, orthodontics is in close relation with dentofacial orthopedics which involves bone regeneration. In this review current and future applications of stem cells (SCs) in orthodontics and dentofacial orthopedics have been discussed. For craniofacial anomalies, SCs have been applied to regenerate hard tissue (such as treatment of alveolar cleft) and soft tissue (such as treatment of hemifacial macrosomia)...
June 26, 2018: World Journal of Stem Cells
Robert L Clark, Monica Schneider, Tina Mahmoudi, Nasir Bashirelahi
Within the last few decades, an increasing number of adults have sought orthodontic therapy. One disadvantage of pursuing orthodontic treatment in adulthood is the lengthened time span required to complete tooth movement. The purpose of this article is to review the biologic mechanisms of accelerated tooth movement as well as the literature on nonsurgical and surgical techniques that may reduce the duration of orthodontic treatment.
July 2018: General Dentistry
Christina L Nicholas, Kevan Kadavy, Nathan E Holton, Teresa Marshall, Andrew Richter, Thomas Southard
INTRODUCTION: Children with high body mass index (BMI) values have been demonstrated to have precocious dental development. Research has largely focused on cross-sectional data sets, leaving an incomplete understanding of the longitudinal relationship between BMI and dental maturation. METHODS: We used a pure longitudinal growth series to examine the relationship between dental development and childhood BMI. Periapical radiographs from 77 children from the Iowa Growth Study were used to estimate dental development for those with high BMI values...
July 2018: American Journal of Orthodontics and Dentofacial Orthopedics
Omar Gibreal, Mohammad Y Hajeer, Bassel Brad
Background: No randomized controlled trial (RCT) has compared flapless piezocision-assisted corticotomy in the extraction-based orthodontic decrowding of lower anterior teeth with the conventional treatment. Objective: To evaluate the effectiveness of flapless piezocision-assisted corticotomies in accelerating lower anterior teeth alignment. Trial design: A parallel-group RCT was conducted. Materials and methods: Thirty-six patients (mean age 20...
June 20, 2018: European Journal of Orthodontics
Saran Arumughan, Sanju Somaiah, Sunil Muddaiah, Balakrishna Shetty, Goutham Reddy, S Roopa
Background and Objectives: A major concern of orthodontic patients is treatment time. Reducing the treatment time requires increasing the rate of orthodontic tooth movement. Research has proved that bone resorption is the rate-limiting step in tooth movement. Therefore, any procedure that potentiates osteoclastic activity is capable of increasing the rate of orthodontic tooth movement. Low-level laser has been indicated to have the capability to facilitate the differentiation of the osteoclastic and osteoblastic cells, which are responsible for the bone remodeling process...
April 2018: Contemporary Clinical Dentistry
Dimitrios Michelogiannakis, P Emile Rossouw, Deema Al-Shammery, Zohaib Akram, Junad Khan, Georgios E Romanos, Fawad Javed
OBJECTIVE: The objective of this systematic review was to assess the impact of nicotine administration on orthodontic tooth movement (OTM). METHODS: A systematic search was conducted in PubMed, Scopus, EMBASE, MEDLINE (OVID) and Web of Knowledge databases and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. Studies evaluating the influence of nicotine on OTM, and with the presence of a control group (OTM without nicotine administration), were included...
May 23, 2018: Archives of Oral Biology
Si-Yu Wang, Zhen-Dong Wang, Bin Yan
The number of adults seeking orthodontic treatment is increasing. Shortening the course of orthodontic treatment has become a research hotspot in recent years. Methods of accelerating tooth movement have been reported. Theoretical and clinical studies have confirmed that periodontal corticotomy is effective in accelerating tooth movement and increasing osteogenic potential. Many surgical techniques of periodontal corticotomy have been developed. This review summarizes the history of periodontal corticotomy and the development of the surgical techniques in recent years, thereby providing references for the clinical application of corticotomy...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
Steffen Stein, Michael Schauseil, Andreas Hellak, Heike Korbmacher-Steiner, Andreas Braun
OBJECTIVE: The objective of this split-mouth trial was to investigate the influence of photobiomodulation therapy (PBMT) on adjuvant treatment of gingivitis induced by multi-bracket appliances, after bracket debonding and professional tooth cleaning. MATERIALS AND METHODS: Thirteen patients (mean age 16.15 years; standard deviation ±2.12 years) who had completed active orthodontic treatment with fixed orthodontic appliances in an orthodontic clinic were included on a randomized basis...
May 18, 2018: Photomedicine and Laser Surgery
Pussadee Phusuntornsakul, Suwanna Jitpukdeebodintra, Prasit Pavasant, Chidchanok Leethanakul
BACKGROUND: Although vibration combined with orthodontic force may accelerate orthodontic tooth movement, little is known about the mechanisms that regulate the associated cellular responses. The propose of this study was to investigate whether mechanical vibration combined with compressive force regulates COX-2/PGE2 , IL-6 and IL-8 mRNA and protein expression in human periodontal ligament (hPDL) cells via the cyclooxygenase pathway. METHODS: The primary cultured hPDL cells were exposed to mechanical vibration, compressive force or a combination of both mechanical vibration and compressive force at 24, 48, 72 h...
May 14, 2018: Journal of Periodontology
Mani Alikhani, Sarah Alansari, Mohammad A Hamidaddin, Chinapa Sangsuwon, Bandar Alyami, Soumya N Thirumoorthy, Serafim M Oliveira, Jeanne M Nervina, Cristina C Teixeira
Vibration in the form of High Frequency Acceleration (HFA) is anabolic on the craniofacial skeleton in the absence of inflammation. Orthodontic forces trigger an inflammation-dependent catabolic cascade that is crucial for tooth movement. It is unknown what effect HFA has on alveolar bone if applied during orthodontic treatment. The objectives of this study are to examine the effect of HFA on the rate of tooth movement and alveolar bone, and determine the mechanism by which HFA affects tooth movement. Adult Sprague Dawley rats were divided to control, orthodontic force alone (OTM), and different experimental groups that received the same orthodontic forces and different HFA regimens...
2018: PloS One
Yina Li, Laura A Jacox, Shannyn H Little, Ching-Chang Ko
Orthodontic tooth movement relies on coordinated tissue resorption and formation in the surrounding bone and periodontal ligament. Tooth loading causes local hypoxia and fluid flow, initiating an aseptic inflammatory cascade culminating in osteoclast resorption in areas of compression and osteoblast deposition in areas of tension. Compression and tension are associated with particular signaling factors, establishing local gradients to regulate remodeling of the bone and periodontal ligament for tooth displacement...
April 2018: Kaohsiung Journal of Medical Sciences
Mostafa Abtahi, Nasrollah Saghravanian, Maryam Poosti, Hooman Shafaee
Background: Reduction of orthodontic treatment time is a major concern for orthodontists. Low level laser therapy (LLL) has been widely used in dentistry and it has been claimed that it could stimulate bone formation. Objective: The aim of the present study was to evaluate histological effects of LLL on alveolar bone remodeling during experimental tooth movement in rabbits. Methods: In this experimental study which was performed in the animal lab of Mashhad Dental School in 2016 twenty pre-pubertal female albino rabbits with the mean age of 8±1 weeks were randomly assigned into two groups...
January 2018: Electronic Physician
Jia Qi Wu, Jiu Hui Jiang, Li Xu, Cheng Liang, Xiu Jing Wang, Yunyang Bai
OBJECTIVE: To identify a panel of differentially expressed candidate biomarkers for patients undergoing accelerated osteogenic orthodontics (AOO). METHODS: This study included 36 saliva samples taken from six Class III surgical patients at six time points: the date before the corticotomy procedure (T1) and at 1 week, 2 weeks, 1 month, 2 months and 6 months after the procedure (T2, T3, T4, T5 and T6, respectively). After the maxillary dental arch was aligned and levelled, AOO procedures were performed in the maxillary alveolar bone...
2018: Chinese Journal of Dental Research
Mina Katchooi, Bobby Cohanim, Sandra Tai, Burcu Bayirli, Charles Spiekerman, Greg Huang
INTRODUCTION: Supplemental vibration has been reported to accelerate orthodontic tooth movement and reduce discomfort. Our purpose was to investigate the effects of AcceleDent on Invisalign treatment. This randomized clinical trial was carried out in 2 orthodontic private practices with a 1:1 allocation ratio. METHODS: Adult patients who were beginning their orthodontic treatment were randomly allocated to either an active (A) or a sham (B) AcceleDent Aura device (OrthoAccel Technologies, Inc...
March 2018: American Journal of Orthodontics and Dentofacial Orthopedics
Kaoru Washio, Yusuke Tsutsumi, Yuka Tsumanuma, Kosei Yano, Supreda Suphanantachat Srithanyarat, Ryo Takagi, Shizuko Ichinose, Walter Meinzer, Masayuki Yamato, Teruo Okano, Takao Hanawa, Isao Ishikawa
Osseointegrated implants have been recognized as being very reliable and having long-term predictability. However, host defense mechanisms against infection have been known to be impaired around a dental implant because of the lack of a periodontal ligament (PDL). The purpose of our experimental design was to produce cementum and PDL on the implant surface adopting cell sheet technology. To this aim we used PDL-derived cells, which contain multipotential stem cells, as the cell source and we cultured them on an implant material constituted of commercially pure titanium treated with acid etching, blasting, and a calcium phosphate (CaP) coating to improve cell attachment...
April 10, 2018: Tissue Engineering. Part A
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