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https://www.readbyqxmd.com/read/29691711/biomechanics-and-mechanical-signaling-in-the-ovary-a-systematic-review
#1
REVIEW
Jaimin S Shah, Reem Sabouni, Kamaria C Cayton Vaught, Carter M Owen, David F Albertini, James H Segars
PURPOSE: Mammalian oogenesis and folliculogenesis share a dynamic connection that is critical for gamete development. For maintenance of quiescence or follicular activation, follicles must respond to soluble signals (growth factors and hormones) and physical stresses, including mechanical forces and osmotic shifts. Likewise, mechanical processes are involved in cortical tension and cell polarity in oocytes. Our objective was to examine the contribution and influence of biomechanical signaling in female mammalian gametogenesis...
April 24, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29691589/gene-expression-profiling-of-the-intact-dermal-sheath-cup-of-human-hair-follicles
#2
Shiro Niiyama, Yumiko Ishimatsu-Tsuji, Yosuke Nakazawa, Yuzo Yoshida, Tsutomu Soma, Ritsuro Ideta, Hideki Mukai, Jiro Kishimoto
Cells that constitute the dermal papillae of hair follicles might be derived from the dermal sheath, the peribulbar component of which is the dermal sheath cup. The dermal sheath cup is thought to include the progenitor cells of the dermal papillae and possesses hair inductive potential; however, it has not yet been well characterized. This study investigated the gene expression profile of the intact dermal sheath cup, and identified dermal sheath cup signature genes, including extracellular matrix components and BMP-binding molecules, as well as TGF-b1 as an upstream regulator...
April 24, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29689834/towards-a-robust-systematic-baseline-of-neotropical-fish-tapeworms-cestoda-proteocephalidae-amended-diagnoses-of-two-genera-from-the-redtail-catfish-phractocephalus-hemioliopterus
#3
Philippe V Alves, Alain de Chambrier, JosÉ L Luque, TomÁŠ Scholz
Species of two monotypic genera, Ephedrocephalus Diesing, 1850 and Zygobothrium Diesing, 1850 (Cestoda: Proteocephalidae), parasites of one of the most basal members of the catfish family Pimelodidae, the redtail catfish, Phractocephalus hemioliopterus, in the Neotropical Region, are redescribed based on the evaluation of type specimens and newly collected material. Generic diagnoses are amended to provide a robust baseline for the future re-arrangement of the classification of proteocephalid cestodes. Ephedrocephalus is typified by the medullary position of the ovary and uterus, the cortical distribution of vitelline follicles (dispersed throughout almost the entire ventral cortex) and the testes in one dorsal field...
January 12, 2018: Zootaxa
https://www.readbyqxmd.com/read/29689526/extended-fish-short-term-reproduction-assays-with-the-fathead-minnow-and-japanese-medaka-no-evidence-of-impaired-fecundity-from-exposure-to-atrazine
#4
Richard A Brain, Suzanne Z Schneider, Julie C Anderson, Loren D Knopper, Jeffrey C Wolf, Mark L Hanson
Short-term reproduction assays were conducted with fathead minnow (Pimephales promelas) and Japanese medaka (Oryzias latipes) to evaluate responses from atrazine exposure at environmentally relevant concentrations and above. Breeding groups of fish with multiple males and females were exposed to atrazine under flow-through conditions. Fathead minnows were exposed to mean measured concentrations of 1.0, 10, 26, 52, and 105 μg atrazine/L for 28 days. Medaka were exposed to mean measured concentrations of 9...
April 16, 2018: Chemosphere
https://www.readbyqxmd.com/read/29688494/discordance-between-serum-anti-m%C3%A3-llerian-hormone-concentrations-and-antral-follicle-counts-not-only-technical-issues
#5
M Š Alebic, N Stojanovic, D Dewailly
STUDY QUESTION: Do patient-specific features contribute to the differences between measured serum anti-Müllerian hormone (AMH) concentrations and AMH values expected from the corresponding antral follicle count (AFC)? SUMMARY ANSWER: Patient-specific features contribute to the differences between measured AMH values and AMH values expected from the corresponding AFC (AMHp), potentially through their effect on follicular AMH production. WHAT IS KNOWN ALREADY: Both patient counselling and patient management could be hampered by finding of disagreement between AFC and AMH if both are used for the prediction of ovarian response...
April 24, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29688269/polycystic-ovary-syndrome-possible-involvement-of-androgen-induced-chemerin-mediated-ovarian-recruitment-of-monocytes-macrophages
#6
Patricia D A Lima, Anne-Laure Nivet, Qi Wang, Yi-An Chen, Arthur Leader, Annie Cheung, Chii-Ruey Tzeng, Benjamin K Tsang
Polycystic ovary syndrome (PCOS) is a continuum of endocrine and reproductive disorders characterized by hyperandrogenism, antral follicle growth arrest and chronic inflammation. Macrophages play key role in inflammation and the balance between M1 (inflammatory) and M2 (anti-inflammatory) macrophages determines physiological/pathological outcomes. Here, we investigated if hyperandrogenism increases ovarian chemerin altering the balance of M1 and M2 macrophages and the granulosa cell death. Ovarian chemerin was up-regulated by 5α-dihydrotestosterone (DHT) in lean and overweight rats; while increased serum chemerin levels were only evident in overweight rats, suggesting that the serum chemerin may be reflective of a systemic response and associated with obesity, whereas increased ovarian chemerin expression is a localized response independent of the metabolic status...
April 24, 2018: Biology of Reproduction
https://www.readbyqxmd.com/read/29687503/are-hormone-measurements-and-ultrasounds-really-predictors-of-sperm-retrieval-in-testicular-sperm-extraction-a-case-report-and-literature-review
#7
G Cito, M E Coccia, R Picone, A Cocci, L Criscuoli, S Dabizzi, G Nesi, S Serni, M Carini, A Natali
Azoospermia can be diagnosed in about 10%-15% of the infertile male population. To overcome the problem of failure to produce spermatozoa in the ejaculate in patients with nonobstructive azoospermia (NOA), testicular sperm extraction (TESE) may be performed to find the focal area of spermatogenesis. A 47-year-old man with NOA presented for treatment of secondary couple infertility. The patient underwent a first TESE 7 years earlier with cryopreservation, and an intracytoplasmic sperm injection-embryo transfer ended in a term pregnancy...
April 23, 2018: Andrologia
https://www.readbyqxmd.com/read/29687080/multidomain-peptide-hydrogel-accelerates-healing-of-full-thickness-wounds-in-diabetic-mice
#8
Nicole C Carrejo, Amanda N Moore, Tania L Lopez Silva, David G Leach, I-Che Li, Douglas R Walker, Jeffrey D Hartgerink
In vivo, multidomain peptide (MDP) hydrogels undergo rapid cell infiltration and elicit a mild inflammatory response which promotes angiogenesis. Over time, the nanofibers are degraded and a natural collagen-based extracellular matrix is produced remodeling the artificial material into natural tissue. These properties make MDPs particularly well suited for applications in regeneration. In this work, we test the regenerative potential of MDP hydrogels in a diabetic wound healing model. When applied to full-thickness dermal wounds in genetically diabetic mice, the MDP hydrogel resulted in significantly accelerated wound healing compared to a clinically used hydrogel, as well as a control buffer...
2018: ACS Biomaterials Science & Engineering
https://www.readbyqxmd.com/read/29686967/an-ovulating-follicle-presenting-as-a-testicular-mass-in-a-teenage-patient-with-ovotesticular-dsd
#9
Joshua D Roth, Nadine G Haddad, Eric A Albright, Liang Cheng, Richard C Rink, Martin Kaefer
No abstract text is available yet for this article.
May 2018: Urology Case Reports
https://www.readbyqxmd.com/read/29686874/influence-of-artificially-induced-light-pollution-on-the-hormone-system-of-two-common-fish-species-perch-and-roach-in-a-rural-habitat
#10
Anika Brüning, Werner Kloas, Torsten Preuer, Franz Hölker
Almost all life on earth has adapted to natural cycles of light and dark by evolving circadian and circannual rhythms to synchronize behavioural and physiological processes with the environment. Artificial light at night (ALAN) is suspected to interfere with these rhythms. In this study we examined the influence of ALAN on nocturnal melatonin and sex steroid blood concentrations and mRNA expression of gonadotropins in the pituitary of European perch ( Perca fluviatilis ) and roach ( Rutilus rutilus ). In a rural experimental setting, fish were held in net cages in drainage channels experiencing either additional ALAN of ~15 lx at the water surface or natural light conditions at half-moon...
2018: Conservation Physiology
https://www.readbyqxmd.com/read/29686164/-treatment-of-rathke-s-cleft-cyst-technical-note-for-preservation-of-pituitary-function
#11
Miiko Ito, Kenichiro Matsuda, Atsushi Kuge, Shinya Sato, Takamasa Kayama, Yukihiko Sonoda
Pituitary dysfunction, such as panhypopituitarism or diabetes insipidus(DI), is often found in patients with Rathke's cleft cyst. Patients were treated with transsphenoidal microscopic surgery; however, pituitary dysfunction did not usually recover. Recently, endoscopic transsphenoidal surgery(eTSS)has enabled minimally invasive surgery for patients with Rathke's cleft cyst. In this study, we analyzed 22 consecutive patients with Rathke's cleft cyst who underwent eTSS to determine if pituitary dysfunction recovered...
April 2018: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/29685707/supplemental-flaxseed-modulates-ovarian-functions-of-weanling-gilts-via-the-action-of-selected-fatty-acids
#12
Radoslava Vlčková, Zuzana Andrejčáková, Drahomíra Sopková, Zdenka Hertelyová, Katarzyna Kozioł, Marek Koziorowski, Soňa Gancarčíková
The aim of this study was to examine the influence of dietary flaxseed on the endocrine and ovarian functions of weanling gilts challenged with E. coli and Coronavirus infections treated with dietary probiotic cheeses and to understand the possible mechanisms of its effects on ovarian function. Probiotics were used as a natural substitution for antibiotics and 10% dietary flaxseed is an effective prebiotic which supports the action of probiotics and has other beneficial effects on the organism. Probiotics with or without flaxseed were fed to weanling gilts starting 10 days before and lasting up until 14 days after weaning...
April 18, 2018: Animal Reproduction Science
https://www.readbyqxmd.com/read/29684814/transcriptional-and-translational-abundance-of-bone-morphogenetic-protein-bmp-2-4-6-7-and-their-receptors-bmpr1a-1b-and-bmpr2-in-buffalo-ovarian-follicle-and-the-role-of-bmp4-and-bmp7-on-estrogen-production-and-survival-of-cultured-granulosa-cells
#13
G Rajesh, S R Mishra, A Paul, M Punetha, G M Vidyalakshmi, K Narayanan, S Bag, S K Bhure, V Singh Chouhan, V P Maurya, G Singh, Mihir Sarkar
BMPs and their receptors modulate the granulosa cell (GC) function in the follicle of domestic animals. Since little is known on BMPs in the buffalo, the present study was aimed to investigate the expression of BMP2, 4, 6, 7 and their receptors BMPR1A, BMPR1B, BMPR2 in the GC and theca cells (TC) of ovarian follicles and the role of BMP4 and BMP7 on buffalo GC. Follicles were classified into four groups based on size and E2 level in the follicular fluid as follows: (i) Group1(4-6 mm; <0.5 ng/mL) (ii) Group 2 (7-9 mm; 0...
April 16, 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29684509/detection-of-lindane-and-7-12-dimethylbenz-a-anthracene-toxicity-at-low-concentrations-in-a-three-dimensional-ovarian-follicle-culture-system
#14
Hong Zhou, Cara J Young, Rita Loch-Caruso, Ariella Shikanov
Exposure to environmental toxicants that target ovarian follicles can have long-lasting effects on women's reproductive health and health of the offspring. Experiments in rodents have contributed knowledge about the effects of individual toxicants on ovarian follicles. However, little is known about the effects of mixtures of toxicants on ovarian follicular health. We studied the combined effects of low, physiologically- and environmentally-relevant concentrations of toxicants on murine secondary ovarian follicles cultured in an encapsulated three-dimensional (3D) system...
April 20, 2018: Reproductive Toxicology
https://www.readbyqxmd.com/read/29684500/the-clinicopathological-comparison-among-nodal-cases-of-idiopathic-multicentric-castleman-disease-with-and-without-tafro-syndrome
#15
Nozomu Kurose, Chizuru Futatsuya, Ken-Ichi Mizutani, Motona Kumagai, Akihiro Shioya, Xin Guo, Akane Aikawa, Satoko Nakada, Shino Fujimoto, Hiroshi Kawabata, Yasufumi Masaki, Kazue Takai, Sadao Aoki, Masaru Kojima, Shigeo Nakamura, Sohsuke Yamada
Multicentric Castleman disease (MCD) is a systemic inflammatory disease potentially caused by an increase in the serum interleukin-6 (IL-6) level. Idiopathic MCD (iMCD) is histopathologically classified into three types: plasmacytic (PC), mixed, and hypervascular (hyperV) types. Recently, a unique clinical phenotype with a poor prognosis overlap with iMCD, thrombocytopenia, anasarca, fever, renal failure or reticulin fibrosis, and organomegaly (TAFRO syndrome), has been reported from Japan, but its detailed clinicopathological features remain unclear...
April 20, 2018: Human Pathology
https://www.readbyqxmd.com/read/29684365/leucocyte-dynamics-during-the-evolution-of-human-coronary-atherosclerosis-conclusions-from-a-7-fold-chromogen-based-immunohistochemical-evaluation
#16
Melissa Zuiderwijk, Marlieke Geerts, Connie Janssen van Rhijn, Antoon van den Bogaerdt, Jaap F Hamming, Rogier A van Dijk, Jan H Lindeman
Atherosclerosis is a complex process with strong inflammatory component. We developed a straightforward 7-fold staining protocol for simultaneous assessment of dominant leucocyte classes, vascularization, and expression of the putative foam cell maker CD36. The method was applied on human coronaries covering the full spectrum of atherosclerotic disease. Results confirm the progressive association of macrophages and T-cells with the process, and a global presence of mast cells. B-cells exclusively present in adventitial follicles that accompany the process plaque destabilization (thin cap and ruptured lesions) and are otherwise absent...
April 20, 2018: American Journal of Pathology
https://www.readbyqxmd.com/read/29684161/impact-of-heat-stress-during-the-follicular-phase-on-porcine-ovarian-steroidogenic-and-phosphatidylinositol-3-signaling
#17
M J Dickson, C L Hager, A Al-Shaibi, P Q Thomas, L H Baumgard, J W Ross, A F Keating
Environmental conditions that impede heat dissipation and increase body temperature cause heat stress (HS). The study objective was to evaluate impacts of HS on the follicular phase of the estrous cycle. Post-pubertal gilts (126.0 ± 21.6 kg) were orally administered altrenogest to synchronize estrus, and subjected to either 5 d of thermal neutral (TN; 20.3 ± 0.5°C; n = 6) or cyclical HS (25.4 - 31.9°C; n = 6) conditions during the follicular phase preceding behavioral estrus. On d 5, blood samples were obtained, gilts were euthanized, and ovaries collected...
April 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29683332/the-impact-of-fshr-gene-polymorphisms-ala307thr-and-asn680ser-in-the-endometriosis-development
#18
Gustavo Mendonça André, Camila Martins Trevisan, Isabela Nacione Pedruzzi, Ramon Felix Martins Fernandes, Renato Oliveira, Denise Maria Christofolini, Bianca Bianco, Caio Parente Barbosa
Endometriosis is an estrogen-dependent inflammatory disease that affects a large number of women in reproductive age. Follicle-stimulating hormone (FSH) plays a role in steroidogenesis and acts through a transmembrane glycoprotein, FSH receptor (FSHR). Polymorphisms in FSHR gene were previously associated with variability in FSH serum level and reproductive outcomes, but its relation with endometriosis has not been clarified and demonstrated conflicting results, ranging from strong links to no association to endometriosis...
April 23, 2018: DNA and Cell Biology
https://www.readbyqxmd.com/read/29683279/hidradenitis-suppurativa-acne-inversa-a-prospective-bacteriological-study-of-46-patients-and-review-of-the-literature
#19
Valentina Benzecry, Anna Grancini, Elena Guanziroli, Gianluca Nazzaro, Mauro Barbareschi, Angelo V Marzano, Simona Muratori, Stefano Veraldi
BACKGROUND: Hidradenitis suppurativa is a chronic inflammatory disease of the hair follicle that usually involves specific anatomic areas which are partially occluded, have a higher density of eccrine and apocrine sweat glands and a higher pH. These characteristics could promote the superinfection of certain group of bacteria. We aimed to describe the bacteria that can be isolated from hidradenitis lesions and to establish a correlation between bacteriological results and clinical data...
April 19, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29683020/premature-ovarian-failure-short-stature-and-hashimoto-s-disease-in-an-18-year-old-adolescent-girl-with-46-x-i-x-q10
#20
Xiang Hu, Qiao Zhang, Feng Gao, Lu-Lu Chen
Premature ovarian failure (POF) is a heterogeneous condition affecting girls and women. We detected a previously healthy 18-year-old adolescent girl, presented with amenorrhea over six months, as well as circulating levels of estradiol lower decreased and follicle-stimulating hormone (FSH) increased. She was 138 cm tall. Results of laboratory tests and/or ultrasound investigations showed 46, X, i(X)(q10) karyotype and Hashimoto's disease. This case suggests that pubertal onset and progression, as well as karyotype analysis, should be evaluated in girls with Hashimoto's disease and short stature...
April 22, 2018: Gynecological Endocrinology
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