keyword
https://read.qxmd.com/read/38643196/apigetrin-ameliorates-doxorubicin-prompted-testicular-damage-biochemical-spermatological-and-histological-based-study
#1
JOURNAL ARTICLE
Muhammad Umar Ijaz, Saba Yaqoob, Ali Hamza, Mehwish David, Tayyaba Afsar, Fohad Mabood Husain, Houda Amor, Suhail Razak
Doxorubicin (DOX) is a highly effective, commonly prescribed, potent anti-neoplastic drug that damages the testicular tissues and leads to infertility. Apigetrin (APG) is an important flavonoid that shows diverse biological activities. The present research was designed to evaluate the alleviative role of APG against DOX-induced testicular damages in rats. Forty-eight adult male albino rats were randomly distributed into 4 groups, control, DOX administered (3 mgkg-1 ), DOX + APG co-administered (3 mgkg-1 of DOX; 15 mgkg-1 of APG), and APG administered group (15 mgkg-1 )...
April 20, 2024: Scientific Reports
https://read.qxmd.com/read/38615860/constructing-network-structures-to-enhance-stability-and-target-deposition-of-selenium-nanoparticles-via-amphiphilic-sodium-alginate-and-alkyl-glycosides
#2
JOURNAL ARTICLE
Xiaona Su, Wenyan Liu, Bei Yang, Shujuan Yang, Jinjian Hou, Gaobo Yu, Yuhong Feng, Jiacheng Li
Dietary selenium (Se) supplementation has recently received increasing attention; however, Selenium nanoparticles (SeNPs) exhibit poor stability and tend to aggregate in aqueous solution. Therefore, enhancing the stability of SeNPs and their effective delivery to plants remain challenging. In this study, sodium alginate (SA) and lysozyme (LZ) were reacted via the wet-heat Maillard reaction (MR) to obtain amphiphilic alginate-based polymers (SA-LZ). Alkyl glycosides (APG) were introduced into SA-LZ to enhance the deposition of SeNPs in leaves...
April 12, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38607492/nonylphenol-ethoxylate-degradation-in-detergents-during-shelf-time-a-new-exposure-pathway-and-a-perspective-on-their-substitution
#3
JOURNAL ARTICLE
Luis Armando Bernal-Jácome, Juan Manuel Izar-Landeta, Rogelio Flores-Ramírez, Luis Fernando González-Salazar, Karla Ximena Vargas-Berrones
Detergents are highly produced pollutants with environmental problems like foam generation and toxic effects in biota. Nonylphenol ethoxylates (NPEs) are efficient, economical, and versatile surfactants, used in detergents for more than 40 years due to their detergency capacity. In the environment, NPE biodegrades into the metabolite nonylphenol (NP), classified as an endocrine disruptor. The identification and quantification of 4-NP in a designed detergent and 30 commercially available detergents were performed to prove the degradation of NPE into 4-NP during storage time...
April 12, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38575864/recognizing-functional-groups-of-mes-apg-mixed-surfactants-for-enhanced-solubilization-toward-benzo-a-pyrene
#4
JOURNAL ARTICLE
Liyuan Wu, Yaxin Liu, Xin Wang, Mengrui Li, Jingya Li, Xiaoran Zhang, Dawen Gao, Haiyan Li
Benzo[ a ]pyrene is difficult to remove from soil due to its high octanol/water partition coefficient. The use of mixed surfactants can increase solubility but with the risk of secondary soil contamination, and the compounding mechanism is still unclear. This study introduced a new approach using environmentally friendly fatty acid methyl ester sulfonate (MES) and alkyl polyglucoside (APG) to solubilize benzo[ a ]pyrene. The best result was obtained when the ratio of MES/APG was 7:1 under 6 g/L total concentration, with an apparent solubility ( S w ) of 8...
April 4, 2024: Environmental Science & Technology
https://read.qxmd.com/read/38568328/novel-insights-into-alkyl-polyglucoside-biosurfactant-promoting-anaerobic-dark-fermentation-for-hydrogen-production-in-sludge
#5
JOURNAL ARTICLE
Xuemei Yang, Tiantian Yang, Yazhou Xu
Anaerobic fermentation of excess sludge (ES) for hydrogen production is a crucial strategy for resource utilization and environmentally friendly treatment. However, the low hydrolysis efficiency of ES and the depletion of produced hydrogen have become the limiting factors for low hydrogen yield. This study innovatively applied the bio-based surfactant alkyl polyglucoside (APG) to enhance the efficiency of dark fermentation for hydrogen production from ES. When the APG content was 100 mg/g (calculated based on total suspended solids), the maximum hydrogen production reached 17...
April 3, 2024: Applied Biochemistry and Biotechnology
https://read.qxmd.com/read/38459102/apigenin-ameliorates-genitourinary-dysfunction-in-a-type-1-diabetic-rat-model-via-drp1-modulation
#6
JOURNAL ARTICLE
Mai Khaled, Raghda A M Salama, Azza Aboughalia, Mai Tarek, Nesma Mohamed Fawzy
The present study aimed to explore the potential ameliorative effect of apigenin (APG) against diabetes-associated genitourinary complications in rats. A diabetic rat model was induced by the intraperitoneal injection of streptozotocin (STZ). All experimental animals were treated with vehicle or vehicle plus APG at a dose of 0.78 mg/kg/day for 10 days, either once diabetes was confirmed or at the end of the 3rd week after confirmation of diabetes. Rats were sacrificed at the end of the fifth week...
March 8, 2024: Scientific Reports
https://read.qxmd.com/read/38428501/noninvasive-measurement-of-ambulatory-venous-pressure-via-column-interruption-duration-in-chronic-venous-disease
#7
JOURNAL ARTICLE
Seshadri Raju, David Thaggard, Owen Barry, Hunter Peeples, Arjun Jayaraj
BACKGROUND: Column interruption duration (CID) is a noninvasive surrogate for venous refill time (VFT), a parameter used in ambulatory venous pressure measurement. CID is more accurate than invasive VFT measurement because it avoids errors involved with indirect access of the deep system through the dorsal foot vein. The aim of this retrospective single center study is to analyze the clinical usefulness of CID in assessment of chronic venous disease (CVD). METHODS: A total of 1551 limbs (777 patients) were referred with CVD symptoms over a 5-year period (2018-2023); CID, air plethysmography, and duplex reflux data were analyzed...
February 28, 2024: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/38414984/molecular-dynamics-investigation-on-the-interfacial-thermal-resistance-between-annealed-pyrolytic-graphite-and-copper
#8
JOURNAL ARTICLE
Xinyu Jiang, Xiaoyang Li, Dong Li, Lizheng Su, Tianning Zhang, Bin Chen, Zhi Li
Modern highly integrated microelectronic products often face the challenge of internal heat dissipation, leading to a significant decrease in their operational efficiency. Annealed Pyrolytic Graphite (APG), due to its superior thermal conductivity, has garnered attention from researchers. The interface thermal resistance between APG and supporting materials like copper significantly affects heat transfer during APG's operation. Existing studies rarely delve into the influence of factors such as the shape of APG material interfaces on thermal resistance from a microscopic perspective...
February 21, 2024: RSC Advances
https://read.qxmd.com/read/38410129/roles-and-inhibitors-of-fak-in-cancer-current-advances-and-future-directions
#9
REVIEW
Hui-Hui Hu, Sai-Qi Wang, Hai-Li Shang, Hui-Fang Lv, Bei-Bei Chen, She-Gan Gao, Xiao-Bing Chen
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that exhibits high expression in various tumors and is associated with a poor prognosis. FAK activation promotes tumor growth, invasion, metastasis, and angiogenesis via both kinase-dependent and kinase-independent pathways. Moreover, FAK is crucial for sustaining the tumor microenvironment. The inhibition of FAK impedes tumorigenesis, metastasis, and drug resistance in cancer. Therefore, developing targeted inhibitors against FAK presents a promising therapeutic strategy...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38404348/plethysmographic-assessment-of-vasomotor-response-in-patients-with-congestive-heart-failure-before-and-after-heart-transplantation
#10
JOURNAL ARTICLE
Oleg V Mamontov, Valeriy V Zaytsev, Alexei A Kamshilin
Sympathetic vasomotor response is the most important part of the autonomic regulation of circulation, which determines the quality of life. It is disrupted in a number of diseases, particularly in patients with congestive heart failure (CHF). However, experimental evaluation of reflex vasoconstriction is still a non-trivial task due to the limited set of available technologies. The aim of this study is to assess the dynamics of vasomotor response of forearm vessels due to both the deactivation of cardiopulmonary baroreceptors and cold stress using a newly designed imaging plethysmograph (IPG) and compare its performance with classical air plethysmograph (APG)...
February 1, 2024: Biomedical Optics Express
https://read.qxmd.com/read/38403980/effectiveness-of-apg-and-honey-gauze-in-pressure-injury-of-elderly-a-randomized-control-trial
#11
JOURNAL ARTICLE
Lulu Xu, Xinmeng Wang, Yongmei Wu, Zhen Zhang, Xiafei Li, Jie Zhang
This study was designed to evaluate the efficiency of the combination of autologous platelet-rich plasma gel (APG) and Manuka honey gauze in the treatment of Stages 3-4 pressure injury of older adults. Patients were divided into four groups: Manuka honey gauze and APG (M + A), Manuka honey gauze (M), APG (A), and a control group (C). Different treatments were given, then wound bed coverage with granulation tissue, wound size reduction, and Pressure Ulcer Scale for Healing (PUSH) score were examined...
February 25, 2024: International Journal of Lower Extremity Wounds
https://read.qxmd.com/read/38397228/the-complete-mitochondrial-genome-of-paeonia-lactiflora-pall-saxifragales-paeoniaceae-evidence-of-gene-transfer-from-chloroplast-to-mitochondrial-genome
#12
JOURNAL ARTICLE
Pan Tang, Yang Ni, Jingling Li, Qianqi Lu, Chang Liu, Jinlin Guo
Paeonia lactiflora ( P. lactiflora ), a perennial plant renowned for its medicinal roots, provides a unique case for studying the phylogenetic relationships of species based on organelle genomes, as well as the transference of DNA across organelle genomes. In order to investigate this matter, we sequenced and characterized the mitochondrial genome (mitogenome) of P. lactiflora . Similar to the chloroplast genome (cpgenome), the mitogenome of P. lactiflora extends across 181,688 base pairs (bp). Its unique quadripartite structure results from a pair of extensive inverted repeats, each measuring 25,680 bp in length...
February 14, 2024: Genes
https://read.qxmd.com/read/38387315/sers-imaging-investigation-of-the-removal-efficiency-of-pesticide-on-vegetable-leaves-by-using-different-surfactants
#13
JOURNAL ARTICLE
Sugui Fang, Li Fan, Yulian Niu, Guoshuai Jiao, Haidong Jia, Feng Wang, Haifeng Yang, Yan Kang
Pesticide residues on vegetables could be removed by commercial detergents to guarantee food safety, but the removal efficiencies of different formulations of detergents need to be further investigated. In this work, surface enhanced Raman scattering (SERS) imaging method due to its good space resolution as well as high sensitivity is used to track the thiram residue, and evaluate the pesticide removing efficiencies by mixtures of several surfactants at different ratios. Sodium linear alkylbenzene sulphonate-alkyl glycoside (LAS-APG) with the ratio at 5:5 and the concentration at 0...
February 10, 2024: Food Chemistry
https://read.qxmd.com/read/38359328/a-feasibility-study-on-enhanced-oil-recovery-of-modified-janus-nano-calcium-carbonate-assisted-alkyl-polyglycoside-to-form-nanofluids-in-emulsification-flooding
#14
JOURNAL ARTICLE
Kaiping Tian, Wanfen Pu, Qianlong Wang, Mengke Xie, Dongdong Wang, Muming Wang, Shun Liu
Emulsification flooding can effectively enhance crude oil recovery to solve the problem of petroleum shortage. In this work, a modified Janus Nano Calcium carbonate (JNC-12) with a particle size of 30-150 nm was synthesized, and an in situ emulsification nanofluid (ISEN) was prepared with JNC-12 and alkyl polyglycoside (APG). Scanning electron microscope (SEM) showed that the dispersion of JNC-12 in air or APG solution was better than Nano Calcium carbonate (Nano CaCO3 ). The emulsification properties, interfacial tension, and expansion modulus of ISEN were studied, and the result showed that with the increase in salinity, the emulsification rate decreased, the water yield rate increased, the interfacial tension first decreased and then increased, and the expansion modulus first increased and then decreased...
February 15, 2024: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/38342074/rapid-and-label-free-a2-peptide-epitope-decorated-cofe-2-o-4-c60-nanocomposite-based-electrochemical-immunosensor-for-detecting-visceral-leishmaniasis
#15
JOURNAL ARTICLE
Darko Kwabena Adu, Zondi Nate, John Alake, Blessing Wisdom Ike, Mavela Cleopus Mahlalela, Sachin Balaso Mohite, Sithabile Mokoena, Ruchika Chauhan, Rajshekhar Karpoormath
Diagnosis of Visceral Leishmaniasis is challenging due to the shared clinical features with malaria, typhoid, and tuberculosis. A CoFe2 O4 -C60 nanocomposite-based immunosensor decorated with a sensitive A2 peptide antigen was fabricated to detect anti-A2 antibodies for application in visceral leishmaniasis diagnosis. The flame-synthesised nanocomposite was characterised using Fourier Transform Infrared spectroscopy (FTIR), X-ray diffraction spectroscopy (XRD), Scanning electron microscopy (SEM), Energy dispersive X-ray spectroscopy (EDX), Raman spectroscopy and electrochemical impedance spectroscopy (EIS) techniques...
February 7, 2024: Bioelectrochemistry
https://read.qxmd.com/read/38322842/assessing-local-people-s-perceptions-of-ecosystem-services-to-support-land-management-plans-in-arid-desert-regions-northwest-china
#16
JOURNAL ARTICLE
Qi Tan, Siru A, Wenying Lang
Deserts play a significant role in terrestrial ecosystems, but their importance is often underestimated in research due to the undervaluation of ecosystem services (ES), particularly the absence of environmental stakeholder perspectives. This study utilized the social science research methodology to investigate the identification and perceptions of desert ES, and the perceived changes in the significance and accessibility of these services following land use alteration among two groups with distinct livelihood strategies in the arid desert region of Northwest China...
February 15, 2024: Heliyon
https://read.qxmd.com/read/38293513/audience-participation-fighting-game-exploring-social-facilitation-for-an-enhanced-apg-experience
#17
JOURNAL ARTICLE
Pujana Paliyawan, Ruck Thawonmas, Kingkarn Sookhanaphibarn, Worawat Choensawat
This paper discusses the popularity of live streaming video games and its potential to address psychological challenges, especially during the COVID-19 pandemic. An audience participation game (APG) that involve massive audiences in gameplay, blurring the lines between viewers and players, is introduced. The game highlights the dynamic adjustment of AI character strengths based on audience inputs, specifically cheering and jeering. The study examines factors that influence user experience (UX) and activeness in APG...
January 30, 2024: Heliyon
https://read.qxmd.com/read/38288358/the-potential-of-autologous-platelet-rich-plasma-gel-for-diabetic-foot-ulcer-care-among-older-adults-a-systematic-review-and-meta-analysis
#18
REVIEW
Hesti Platini, Keyzha Amartya Adammayanti, Sidik Maulana, Putu Moradha Kharisma Putri, Welly Grivin Layuk, Juan Alessandro Jeremis Maruli Nura Lele, Hartiah Haroen, Sri Hartati Pratiwi, Faizal Musthofa, Arpit Mago
INTRODUCTION: Poorly controlled diabetes mellitus can lead to the development of diabetic foot ulcers (DFU), which is a frequent complication in patients. However, several diabetes management guidelines for older adults do not mention the occurrence of DFUs. Nowadays, Autologous Platelet-Rich Gel (APG) is being used for treating diabetic ulcers. APG is an innovative platelet-derived product with many advantages, such as being low-cost, easy to produce, and readily available materials...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38275903/rationale-for-increasing-oncological-vigilance-in-relation-to-clinical-findings-in-accessory-parotid-gland-observations-based-on-2192-cases-of-the-polish-salivary-network-database
#19
JOURNAL ARTICLE
Małgorzata Wierzbicka, Ewelina Bartkowiak, Wioleta Pietruszewska, Dominik Stodulski, Jarosław Markowski, Paweł Burduk, Izabela Olejniczak, Aleksandra Piernicka-Dybich, Małgorzata Wierzchowska, Katarzyna Amernik, Alicja Chańko, Daniel Majszyk, Antoni Bruzgielewicz, Patrycja Gazinska, Bogusław Mikaszewski
The accessory parotid gland (APG, Vth level) differs in histological structure from main parotid tissue. This gives rise to the hypothesis, mirrored in clinical observations, that the representation of tumours is different than in the rest of the gland. The aim of the study was to analyse the epidemiological and histological differences of parotid tumours located in regions I-V, with particular emphasis on the distinctiveness of region V. To define the epidemiological factors that will indicate the risk of histological malignancy from clinically benign appearance, multicentre prospective studies conducted between 2017-2021 by five Head and Neck Surgery University Departments, cooperating within the Polish Salivary Network Database 1929 patients (1048 women and 881 men), were included...
January 22, 2024: Cancers
https://read.qxmd.com/read/38257121/diagnostic-ultrasound-based-investigation-of-central-vs-peripheral-arterial-changes-consequent-to-low-dose-caffeine-ingestion
#20
JOURNAL ARTICLE
Yu-Bin Jin, Jeong-Hyeon Kim, Chae-Hyeon Song, Chansol Park, Chang-Ki Kang
Caffeine is present in various foods and medicines and is highly accessible through various routes, regardless of age. However, most studies on caffeine have focused on the effects of high-dose caffeine ingestion based on the recommended daily amount for adults. In this study, we examined the physiological changes in the central and peripheral vessels that may occur when ingesting low-dose caffeine due to its high accessibility, with the aim of creating an environment of safe caffeine ingestion. This study included 26 healthy participants in their 20s...
January 10, 2024: Nutrients
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