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Arterial hypertension and age

Ilana E Green, Shareena A Rahman, Debra L Owens, Michèle M Sale, Lillian J Currie, Keith L Keene, Bradford B Worrall, Andrew M Southerland
BACKGROUND AND PURPOSE: The majority of published data in cervical artery dissection (CeAD), a common cause of stroke in young adults, derive from populations of European ancestry (EA), including a recent genome-wide study identifying an association with the rs9349379 polymorphism of the PHACTR1 gene. Little is known about CeAD in individuals of African ancestry (AA) despite robust epidemiological data showing increased risk of stroke at younger ages. We hypothesize that AA patients with CeAD have different epidemiology and clinical profiles compared to those of EA, and a different genetic architecture related to rs9349379 of the PHACTR1 gene...
December 5, 2018: Cerebrovascular Diseases
Deborah Carvalho Malta, Renata Patrícia Fonseca Gonçalves, Ísis Eloah Machado, Maria Imaculada de Fátima Freitas, Cimar Azeredo, Celia Landman Szwarcwald
OBJECTIVE: To determine the population prevalence of arterial hypertension in adults according to different diagnostic criteria. METHODS: This is a cross-sectional study, analyzing information from the Brazilian National Health Survey in 2013, consisted of interviews, physical and laboratory measurements (n = 60,202). The prevalence of hypertension was defined according to three diagnostic criteria: self-reported; measured by instrument (blood pressure ≥ 140/90 mmHg); measured and/or using medication...
November 29, 2018: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
Jane Laner Cardoso, Claudio Leone
INTRODUCTION: The prevalence of systemic arterial hypertension in childhood has increased progressively. OBJECTIVE: To analyze blood pressure and height reached by children in public schools in the South of Brazil. METHODS: This is a sectional study of a randomized sample of 1,082 students of six to seven and nine to ten years old used to evaluate blood pressure and height. Blood pressure levels were classified by percentile for gender, age and stature according to the North American reference of National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents...
October 2018: Revista da Associação Médica Brasileira
Duygu Koçyiğit, Lale Tokgözoğlu, Meral Kayıkçıoğlu, Servet Altay, Sinan Aydoğdu, Cem Barçın, Cem Bostan, Hüseyin Altuğ Çakmak, Alp Burak Çatakoğlu, Samim Emet, Oktay Ergene, Ali Kemal Kalkan, Barış Kaya, Cansın Kaya, Cihangir Kaymaz, Nevrez Koylan, Hakan Kültürsay, Aytekin Oğuz, Ebru Özpelit, Serkan Ünlü
OBJECTIVE: It has been reported that women receive fewer preventive recommendations regarding pharmacological treatment, lifestyle modifications, and cardiac rehabilitation compared with men who have a similar risk profile. This study was an investigation of the impact of gender on cardiovascular risk profile and secondary prevention measures for coronary artery disease (CAD) in the Turkish population. METHODS: Statistical analyses were based on the European Action on Secondary and Primary Prevention through Intervention to Reduce Events (EUROASPIRE)-IV cross-sectional survey data obtained from 17 centers in Turkey...
December 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
M Hrebenyk, L Zelenenka, L Zoria, S Maslii
The clinical experience implies poor prognosis in women with myocardial infarction (MI). We performed a retrospective cohort study of 1395 patients - 987 (70,75%) men and 408 (29,25%) women) aged of 64,63±11,43 years with myocardial infarction and comorbidity hospitalized between 2010-2016. This study shows an increase of mortality in women with myocardial infarction during the last 4 years from 23,1% to 34,2%. We observed more frequent cases of non-STEMI (p=0,014) and recurrent myocardial infarction in females compared with males (р<0,0001)...
October 2018: Georgian Medical News
Mustafa Dogdus, Evrim Simsek, Cahide Soydas Cinar
BACKGROUND AND AIM: Stable angina pectoris is a common disease that may cause disability. Some noninvasive new methods can be useful for the detection of early-stage coronary artery disease. The relationship between coronary artery disease (CAD) severity and resting 3-dimensional-speckle tracking echocardiography (3D-STE) in stable angina pectoris patients was evaluated in this study. METHODS: One hundred and twenty consecutive patients between 18-80 years of age and without a history of CAD to whom elective coronary angiography was planned after positive stress test or myocardial perfusion scintigraphy were enrolled in the study...
December 4, 2018: Echocardiography
Stylianos Panopoulos, Maria Tektonidou, Alexandros A Drosos, Stamatis-Nick Liossis, Theodoros Dimitroulas, Alexandros Garyfallos, Lazaros Sakkas, Dimitrios Boumpas, Paraskevi V Voulgari, Dimitrios Daoussis, Konstantinos Thomas, Georgios Georgiopoulos, Georgios Vosvotekas, Dimitrios Vassilopoulos, Petros P Sfikakis
BACKGROUND: Comorbidities are common in chronic systemic connective tissue diseases and are associated with adverse outcomes, increased morbidity and mortality. Although the prevalence of comorbidities has been well-studied in isolated diseases, comparative studies between different autoimmune diseases are limited. In this study, we compared the prevalence of common comorbidities between patients with systemic sclerosis (SSc) and patients with rheumatoid arthritis (RA). METHODS: Between 2016 and 2017, 408 consecutive patients with SSc, aged 59 ± 13 years (87% women), were matched 1:1 for age and gender with 408 patients with RA; mean disease duration was 10 ± 8 and 9 ± 8 years, respectively...
December 4, 2018: Arthritis Research & Therapy
C Antza, I Doundoulakis, M Natsis, V Kotsis
Artery disease can be identified from ankle-brachial index (peripheral artery disease), pulse wave velocity (arterial stiffness), carotid intima media thickness (atherosclerosis) and flow-mediated dilation (endothelial disfunction). Arterial stiffness is a marker of cardiovascular disease associated with cardiovascular events. Increased vascular ageing is the acceleration of arterial stiffness inappropriate for the given chronological age. Treatment of early vascular ageing seems to be important if we target on primary cardiovascular prevention...
December 4, 2018: Current Pharmaceutical Design
Laura Roli, Agnese Veronesi, Maria C De Santis, Enrica Baraldi
BACKGROUND: Sparse metanephrines reference intervals in pediatric populations are available and different study designs and technologies/ assays used in these studies lead to hardly transferable data from a laboratory to another. The objective of the study was to update pediatric reference intervals of total fractionated metanephrines in spot urine samples, using a commercial extraction kit run on a specific high pressure liquid chromatograph coupled with an electrochemical detector. METHODS: 452 spot pediatric urinary samples previously submitted to urinalysis were consecutively included in the study with the exclusion of children's samples with diagnosis or clinical suspicion of paraganglioma/pheochromocytoma, kidney diseases and arterial hypertension...
December 3, 2018: Minerva Pediatrica
Maryam Tayefi, Niloofar Shabani, Maryam Saberi-Karimian, Mohammadreza Oladi, Mohsen Mouhebati, Zahra Farjami, Zeinab Sadat Hoseini, Maryam Mohammadi-Bajgyran, Ali Asghar Mahmoudi, Marzieh Eidi Doustabad, Gordon A Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan
Hypertension (HTN) is a major risk factor for coronary artery disease. Its frequency is increasing globally. The aim of our study was to evaluate the reference range of blood pressure (BP) in the Iranian population stratified for age and gender. A total of 1449 subjects without diabetes, CVD, dyslipidemia, HTN history and with a normal BMI (18.5 ≤ BMI<25) were recruited in the present study. Participants were enrolled from the Mashhad stroke and heart atherosclerotic disorder study. Anthropometric indices and demographic data were collected by two health care specialists...
November 22, 2018: Journal of the American Society of Hypertension: JASH
Martin G Schultz, Chloe Park, Abigail Fraser, Laura D Howe, Siana Jones, Alicja Rapala, George Davey Smith, James E Sharman, Deborah A Lawlor, Nish Chaturvedi, John Deanfield, Alun D Hughes
PURPOSE: Dynamic exercise results in increased systolic blood pressure (BP). Irrespective of resting BP, some individuals may experience exaggerated rise in systolic BP with exercise, which in adulthood is associated with risk of hypertension, and cardiovascular (CV) disease. It is unknown if exercise BP is associated with markers of CV structure during adolescence. We examined this question in a large adolescent cohort taking account of the possible confounding effect of body composition and BP status...
January 15, 2019: International Journal of Cardiology
Ralphe Bou Chebl, Gilbert Abou Dagher, Jeffrey Wuhantu, Rana Bachir, Jennifer Carnell
BACKGROUND: Fluid responsiveness is an important topic for clinicians. Aggressive hydration has been shown to lead to worse outcomes. The aim of this study was to investigate the sensitivity and specificity of mitral valve (MV) velocity time integral (VTI) as a non-invasive marker of volume responsiveness. METHODS: This was a prospective observational study conducted in a tertiary emergency department. End-stage renal disease patients presenting to the emergency department requiring emergent hemodialysis were enrolled...
December 2, 2018: Critical Ultrasound Journal
Xue Yu, Zhiwei Huang, Yi Zhang, Zhihong Liu, Qin Luo, Zhihui Zhao, Qing Zhao, Liu Gao, Qi Jin, Lu Yan
Background: Due to its effects, like an exaggerated negative intrathoracic pressure, sympathetic activation, systemic inflammation, oxidative stress, and endothelial dysfunction, obstructive sleep apnea (OSA) has been involved as a cause in multiple cardiovascular diseases. These diseases include coronary artery disease, hypertension, heart failure, and pulmonary hypertension (PH). Furthermore, OSA often coexists with chronic thromboembolic pulmonary hypertension (CTEPH) in clinical practice...
October 2018: Journal of Thoracic Disease
Iyad Farah, Amjad M Ahmed, Raed Odeh, Eltayyeb Alameen, May Al-Khateeb, Elias Fadel, Raid Rabai, Dalia Ali, Bassam Bdeir, Mouaz H Al-Mallah
Background: Despite the availability of new potent medical therapies, the rate of progression of angiographic coronary artery disease (CAD) is not well described. The aim of this analysis is to describe the rate and predictors of progression of CAD among patients with recurrent symptoms. Materials and Methods: We reviewed 259 patients (mean age 61 ± 11 years, 70% males) who underwent two coronary angiograms between 2008 and 2013. Progressive CAD was defined as obstructive CAD in a previously disease-free segment or new obstruction in a previously nonobstructive segment...
April 2018: Heart Views: the Official Journal of the Gulf Heart Association
Małgorzata Kurpaska, Paweł Krzesiński, Grzegorz Gielerak, Beata Uziębło-Życzkowska, Małgorzata Banak, Adam Stańczyk, Katarzyna Piotrowicz
Patients with arterial hypertension (AH), especially women, often report exercise intolerance and dyspnea. However, these symptoms are not frequently reflected in standard assessments. The aim of the study was to evaluate the clinical value of impedance cardiography (ICG) in the hemodynamic assessment of patients with AH during exercise, particularly the differences between subgroups based on sex and the presence of dyspnea. Ninety-eight patients with AH (52 women; 54.5 ± 8.2 years of age) were evaluated for levels of N-terminal pro-B-type brain natriuretic peptide (NT-proBNP), exercise capacity (cardiopulmonary exercise testing (CPET) and the 6-min walk test (6MWT)), and exercise ICG...
November 30, 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
Bo Yang, Qi Wang, Rui Wang, Tao Xu
BACKGROUND/AIMS: Cardiovascular complications are the most common cause of death in individuals with autosomal dominant polycystic kidney disease (ADPKD), yet there is no substantial data concerning the clinical characteristics of acute myocardial infarction (AMI) in this population. This study thus aimed to investigate AMI in persons with ADPKD. METHODS: A retrospective analysis of ADPKD patients admitted to our hospital over a 13 year period was conducted. Age and gender-matched control patients without ADPKD were also selected at a ratio of 1: 10...
November 30, 2018: Kidney & Blood Pressure Research
Benjamin Strauss, Yassine Sassi, Carlos Bueno-Beti, Zeki Ilkan, Nour Raad, Marine Cacheux, Malik Bisserier, Irene C Turnbull, Erik Kohlbrenner, Roger J Hajjar, Lahouaria Hadri, Fadi G Akar
BACKGROUND: Pulmonary arterial hypertension (PAH) results in right ventricular (RV) failure, electro-mechanical dysfunction and heightened risk of sudden cardiac death (SCD), although exact mechanisms and predisposing factors remain unclear. Because impaired chronotropic response to exercise is a strong predictor of early mortality in patients with PAH, we hypothesized that progressive elevation in heart rate can unmask ventricular tachyarrhythmias (VT) in a rodent model of monocrotaline (MCT)-induced PAH...
November 28, 2018: Journal of Molecular and Cellular Cardiology
Jidong Sung, Soo Jin Cho, Kyong Pyo Hong
BACKGROUND: There is a well-established relationship between cardiorespiratory fitness (CRF) and arterial stiffness. However, it is unclear whether this relationship differs significantly between hypertensive and non-hypertensive patients. METHODS: Adults without a history of ischemic heart disease or stroke and normal exercise test results who underwent health screening were included. Cardiopulmonary function test was performed using the Bruce protocol. Peak oxygen consumption (VO2peak) was measured...
November 30, 2018: Clinical and Experimental Hypertension: CHE
O D Ostroumova
Essential arterial hypertension (AH) is one of the main risk factors for the development of cognitive impairment and dementia. Cognitive decline is an early sign of brain damage as a target organ of hypertension, it occurs even in patients with uncomplicated hypertension with minimal duration of disease. Cognitive impairment progresses with increasing age and hypertension duration, as well as in non-controlled AH. In patients with hypertension, the prevalence of emotional disorders - anxiety and depression is also high...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
William P Shutze, Ryan Shutze, Paul Dhot, Moses Forge, Alejandro Salazar, Gerald O Ogola
BACKGROUND: Several vascular surgical procedures, including repair of abdominal aortic aneurysms (AAAs), show poorer outcomes for women than for men. We evaluated the impact of sex-based demographic differences on survival after endovascular aneurysm repair (EVAR). METHODS: We reviewed EVARs performed at our institution between 2003 and 2009 and assessed aortic neck variables (length, diameter, angulation, and calcification), iliac artery variables (length, tortuosity, angulation, and calcification), and AAA diameter...
November 26, 2018: Journal of Vascular Surgery
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