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https://www.readbyqxmd.com/read/30066277/visual-cortex-neural-activity-alteration-in-cervical-spondylotic-myelopathy-patients-a-resting-state-fmri-study
#1
Zhao Chen, Qiu Wang, Meng Liang, Rui Zhao, Jiajia Zhu, Wuyi Xiong, Zhe Su, Chunshui Yu, Yuan Xue
PURPOSE: We sought to investigate visual cortex neural activity and functional connectivity (FC) alterations in cervical spondylotic myelopathy (CSM) patients using resting-state fMRI (rs-fMRI) and to explore the relationships of these alterations with visual disorder. METHODS: Twenty-seven CSM patients and 11 healthy controls were recruited as the study and control groups. The amplitude of low-frequency fluctuations (ALFF) and regional homogeneity (ReHo) values were calculated to represent neural activity, seed-based correlation analysis (SCA) was performed to analyze the FC of visual cortex, and the outcomes were compared between groups...
July 31, 2018: Neuroradiology
https://www.readbyqxmd.com/read/29574593/longitudinal-brain-activation-changes-related-to-electrophysiological-findings-in-patients-with-cervical-spondylotic-myelopathy-before-and-after-spinal-cord-decompression-an-fmri-study
#2
Lumír Hrabálek, Pavel Hok, Petr Hluštík, Eva Čecháková, Tomáš Wanek, Pavel Otruba, Miroslav Vaverka, Petr Kaňovský
BACKGROUND: Cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord dysfunction, potentially leading to severe disability. Abnormal cervical spine magnetic resonance imaging (MRI) and motor evoked potentials (MEPs) are independent predictors of disease progression. Abnormal MRI is accompanied by various activation changes in functional brain MRI (fMRI), whereas preoperative and postoperative fMRI adaptations associated with abnormal preoperative MEP remain unknown...
May 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28716297/on-the-relative-merits-of-invasive-and-non-invasive-pre-surgical-brain-mapping-new-tools-in-ablative-epilepsy-surgery
#3
Andrew C Papanicolaou, Roozbeh Rezaie, Shalini Narayana, Asim F Choudhri, Abbas-Babajani-Feremi, Frederick A Boop, James W Wheless
Cortical Stimulation Mapping (CSM) and the Wada procedure have long been considered the gold standard for localizing motor and language-related cortical areas and for determining the language and memory-dominant hemisphere, respectively. In recent years, however, non-invasive methods such as magnetoencephalography (MEG), functional magnetic resonance imaging (fMRI), and transcranial magnetic stimulation (TMS) have emerged as promising alternatives to the aforementioned procedures, particularly in cases where the invasive localization of eloquent cortex has proven to be challenging...
May 2018: Epilepsy Research
https://www.readbyqxmd.com/read/27907060/amplitude-of-low-frequency-fluctuation-alff-in-the-cervical-spinal-cord-with-stenosis-a-resting-state-fmri-study
#4
Xiaojia Liu, Wenshu Qian, Richu Jin, Xiang Li, Keith Dk Luk, Ed X Wu, Yong Hu
Cervical spondylotic myelopathy (CSM) is a common spinal cord dysfunction disease with complex symptoms in clinical presentation. Resting state fMRI (rsfMRI) has been introduced to study the mechanism of neural development of CSM. However, most of those studies focused on intrinsic functional connectivity rather than intrinsic regional neural activity level which is also frequently analyzed in rsfMRI studies. Thus, this study aims to explore whether the level of neural activity changes on the myelopathic cervical cord and evaluate the possible relationship between this change and clinical symptoms through amplitude of low frequency fluctuation (ALFF)...
2016: PloS One
https://www.readbyqxmd.com/read/27246485/functional-cortical-reorganization-in-cases-of-cervical-spondylotic-myelopathy-and-changes-associated-with-surgery
#5
Indira Devi Bhagavatula, Dhaval Shukla, Nishanth Sadashiva, Praveen Saligoudar, Chandrajit Prasad, Dhananjaya I Bhat
OBJECTIVE The physiological mechanisms underlying the recovery of motor function after cervical spondylotic myelopathy (CSM) surgery are poorly understood. Neuronal plasticity allows neurons to compensate for injury and disease and to adjust their activities in response to new situations or changes in their environment. Cortical reorganization as well as improvement in corticospinal conduction happens during motor recovery after stroke and spinal cord injury. In this study the authors aimed to understand the cortical changes that occur due to CSM and following CSM surgery and to correlate these changes with functional recovery by using blood oxygen level-dependent (BOLD) functional MRI (fMRI)...
June 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/26787180/-influence-of-cervical-spondylotic-spinal-cord-compression-on-cerebral-cortical-adaptation-radiological-study
#6
L Hrabálek, P Hluštík, P Hok, E Čecháková, T Wanek, P Otruba, M Vaverka, P Kaňovský
PURPOSE OF THE STUDY: The aim of the study was to measure the sensorimotor brain adaptation activity, shown on functional magnetic resonance images (fMRI), in relation to the degree and extent of spinal cord compression or cervical spondylotic myelopathy (CSM) detected by cervical spine MRI. MATERIAL AND METHODS: Twenty-one patients (average age, 57 years; 9 men and 12 women) with anterior cervical cord compression detected on cervical MRI scans were included. On the images, the degree of spinal canal stenosis, the spinal cord compression based on the antero-posterior diameter of the spinal canal and on transverse areas of the cervical spinal cord and cervical spinal canal, and changes in spinal cord signal intensity were identified...
2015: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/26679420/language-mapping-using-high-gamma-electrocorticography-fmri-and-tms-versus-electrocortical-stimulation
#7
Abbas Babajani-Feremi, Shalini Narayana, Roozbeh Rezaie, Asim F Choudhri, Stephen P Fulton, Frederick A Boop, James W Wheless, Andrew C Papanicolaou
OBJECTIVE: The aim of the present study was to compare localization of the language cortex using cortical stimulation mapping (CSM), high gamma electrocorticography (hgECoG), functional magnetic resonance imaging (fMRI), and transcranial magnetic stimulation (TMS). METHODS: Language mapping using CSM, hgECoG, fMRI, and TMS were compared in nine patients with epilepsy. Considering CSM as reference, we compared language mapping approaches based on hgECoG, fMRI, and TMS using their sensitivity, specificity, and the results of receiver operating characteristic (ROC) analyses...
March 2016: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/26605335/alteration-of-regional-homogeneity-within-the-sensorimotor-network-after-spinal-cord-decompression-in-cervical-spondylotic-myelopathy-a-resting-state-fmri-study
#8
Yongming Tan, Fuqing Zhou, Lin Wu, Zhili Liu, Xianjun Zeng, Honghan Gong, Laichang He
There is a lack of longitudinal research to evaluate the function of neurons' adaptive changes within the sensorimotor network (SMN) following recovery after cervical cord decompression. Regional homogeneity (ReHo) may provide information that is critical to fully understand CSM-related functional neural synchrony alterations. The purpose of this study was to assess the ReHo alterations of resting state-functional MRI (rs-fMRI) within pre- and postdecompression CSM and healthy controls (HC) and its correlations with clinical indices...
2015: BioMed Research International
https://www.readbyqxmd.com/read/25418940/-effects-of-spinal-cord-decompression-in-patients-with-cervical-spondylotic-myelopathy-oncortical-brain-activations
#9
L Hrabálek, P Hluštík, P Hok, T Wanek, P Otruba, E Cecháková, M Vaverka, P Kaňovský
INTRODUCTION: The aim of this project was to compare and evaluate cortical sensorimotor adaptations as measured by brain fMRI (functional magnetic resonance imaging) in patients before and after surgery for cervical spondylotic myelopathy (CSM), i.e., after spinal cord decompression. MATERIAL AND METHODS: Study inclusion required evidence of CSM on MRI of the cervical spine, anterior compression of the spinal cord by osteophytes, or disc herniation. We measured the antero-posterior diameter of the spinal canal stenosis before and 3 months after surgery...
November 2014: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/24815217/cortical-cartography-reveals-political-and-physical-maps
#10
COMPARATIVE STUDY
David W Loring, William Davis Gaillard, Susan Y Bookheimer, Kimford J Meador, Jeffrey G Ojemann
Advances in functional imaging have provided noninvasive techniques to probe brain organization of multiple constructs including language and memory. Because of high overall rates of agreements with older techniques, including Wada testing and cortical stimulation mapping (CSM), some have proposed that those approaches should be largely abandoned because of their invasiveness, and replaced with noninvasive functional imaging methods. High overall agreement, however, is based largely on concordant language lateralization in series dominated by cases of typical cerebral dominance...
May 2014: Epilepsia
https://www.readbyqxmd.com/read/11725858/the-neural-representation-of-language-in-users-of-american-sign-language
#11
D P Corina, S L McBurney
UNLABELLED: Studies of American Sign Language (ASL) offer unique insights into the fundamental properties of human language. Neurolinguistic studies explore the effects of left and right hemisphere lesions on the production and comprehension of signed language. Following damage to the left hemisphere perisylvian regions, signers, like users of spoken languages, exhibit frank aphasic disturbances. Sign language paraphasia illustrates the linguistic specificity of impairment. A case study involving cortical stimulation mapping (CSM) in a deaf signer provides evidence for the specialization of Broca's area in sign language production...
November 2001: Journal of Communication Disorders
https://www.readbyqxmd.com/read/11169872/detection-of-fmri-activation-using-cortical-surface-mapping
#12
COMPARATIVE STUDY
A Andrade, F Kherif, J F Mangin, K J Worsley, A L Paradis, O Simon, S Dehaene, D Le Bihan, J B Poline
A methodology for fMRI data analysis confined to the cortex, Cortical Surface Mapping (CSM), is presented. CSM retains the flexibility of the General Linear Model based estimation, but the procedures involved are adapted to operate on the cortical surface, while avoiding to resort to explicit flattening. The methodology is tested by means of simulations and application to a real fMRI protocol. The results are compared with those obtained with a standard, volume-oriented approach (SPM), and it is shown that CSM leads to local differences in sensitivity, with generally higher sensitivity for CSM in two of the three subjects studied...
February 2001: Human Brain Mapping
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