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Catrin Lewis, Neil P Roberts, Andrew Bethell, Lindsay Robertson, Jonathan I Bisson
BACKGROUND: Therapist-delivered trauma-focused psychological therapies are an effective treatment for post-traumatic stress disorder (PTSD). These have become the accepted first-line treatments for the disorder. Despite the established evidence-base for these therapies, they are not always widely available or accessible. Many barriers limit treatment uptake, such as the limited number of qualified therapists to deliver the interventions, cost, and compliance issues, such as time off work, childcare, and transportation, associated with the need to attend weekly appointments...
December 14, 2018: Cochrane Database of Systematic Reviews
Amy A Gorin, Jessica Gokee LaRose, Mark A Espeland, Deborah F Tate, Elissa Jelalian, Erica Robichaud, Pamela Coward, Karen E Hatley, Katelyn R Garcia, Wei Lang, Judy Bahnson, Cora E Lewis, Rena R Wing
OBJECTIVE: Self-regulation interventions encouraging daily weighing prevent weight gain in young adults; however, concerns have been raised that such interventions may have undesirable effects on eating pathology, depression, and health-related quality of life (HRQL). The present study examined whether self-regulation interventions and self-weighing frequency were associated with these indices in normal weight individuals and those with overweight or obesity. METHODS: Young adults ( n = 599), 18-35 years with a body mass index (BMI) 21...
December 13, 2018: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
Ludmila N Bakhireva, Maureen A Kane, Cynthia F Bearer, Adriana Bautista, Jace W Jones, Laura Garrison, Mae-Gilene Begay, Timothy Ozechowski, Johnnye Lewis
BACKGROUND: Although fetal alcohol spectrum disorders represent a significant public health problem, Native Americans are underrepresented in population and targeted screening programs. Prior reports suggest that Native American tribal communities may have a higher prevalence of alcohol use during pregnancy; however, systematic examination using ethanol biomarkers is lacking. METHODS: This study utilized data collected through the Navajo Birth Cohort Study (NBCS)-a birth cohort study of a Southwestern tribal community...
December 14, 2018: Birth Defects Research
David G Coughlin, Sharon X Xie, Mendy Liang, Andrew Williams, Claire Peterson, Daniel Weintraub, Corey T McMillan, David A Wolk, Rizwan S Akhtar, Howard Hurtig, H Branch Coslett, Roy Hamilton, Andrew Siderowf, John E Duda, Katya Rascovsky, Edward B Lee, Virginia M-Y Lee, Murray Grossman, John Q Trojanowski, David J Irwin
OBJECTIVE: To use digital histology in a large autopsy cohort of Lewy Body Disorder (LBD) patients with dementia to test the hypotheses that co-occurring Alzheimer's disease (AD) pathology impacts the anatomic distribution of α-synuclein (SYN) pathology and that co-occurring neocortical tau pathology in LBD associates with worse cognitive performance and occurs in a pattern differing from AD. METHODS: Fifty-five autopsy-confirmed LBD (PDD: 36, DLB:19) patients and 25 AD patients were studied...
December 14, 2018: Annals of Neurology
Andrea Deissenberger, Eileen Welz, Regina Drescher, Ivo Krummenacher, Rian Dewhurst, Bernd Engels, Holger Braunschweig
A new structural class of boron-based diradicals is prepared by Lewis-base addition to and reduction of singly CAAC-stabilised diborylalkenes. The diradicals feature a perpendicular olefinic bridge preventing delocalization between the B(CAAC) π systems, making the coupling between the spin centres very weak. DFT calculations indicate that the compounds are ground-state (open-shell) singlets, with triplet states negligibly higher in energy, thus making the latter easily populated thermally.
December 14, 2018: Angewandte Chemie
Frances Marcus Lewis, Kristin A Griffith, Zainab Alzawad, Patricia L Dawson, Ellen H Zahlis, Mary Ellen Shands
OBJECTIVE: To test the short-term efficacy of a brief, fully manualized marital communication and interpersonal support intervention for couples facing recently diagnosed breast cancer. METHODS: A total of 322 women diagnosed within 6 months with Stage 0-III breast cancer and their 322 spouse caregivers were enrolled. Spouses in the experimental group received five, 30 to 60-minute intervention sessions at 2-week intervals by Masters prepared patient educators; controls received the booklet, "What's Happening to the Woman I Love?" Outcomes were assessed at 3, 6 and 9 months using Linear Mixed Models within an intent to treat analysis...
December 13, 2018: Psycho-oncology
Masato Ishibashi, Noriyuki Kimura, Kaori Sumi, Yasuhiro Aso, Etsuro Matsubara
AIM: The aim of the present study was to examine the differences in the brain perfusion single-photon emission computed tomography patterns compared in dementia with Lewy bodies (DLB) with or without cingulate island sign (CIS). METHODS: A total of 43 patients with DLB and 63 patients with Alzheimer's disease (AD) were included in the study. The CIScore was determined based on the posterior cingulate area and the occipital cortex using the eZIS software. The CIScore was analyzed using receiver operating characteristic curve analysis...
December 12, 2018: Geriatrics & Gerontology International
Mark K L Wong, Benoit Guénard, Owen T Lewis
In focusing on how organisms' generalizable functional properties (traits) interact mechanistically with environments across spatial scales and levels of biological organization, trait-based approaches provide a powerful framework for attaining synthesis, generality and prediction. Trait-based research has considerably improved understanding of the assembly, structure and functioning of plant communities. Further advances in ecology may be achieved by exploring the trait-environment relationships of non-sessile, heterotrophic organisms such as terrestrial arthropods, which are geographically ubiquitous, ecologically diverse, and often important functional components of ecosystems...
December 13, 2018: Biological Reviews of the Cambridge Philosophical Society
Kaina Zhou, Minjie Li, Wen Wang, Jinghua An, Lanting Huo, Xiaole He, Jin Li, Guihua Zhuang, Xiaomei Li
RATIONALE, AIMS, AND OBJECTIVES: The psychometrics of the Short-Form 36 Health Survey version 2 (SF-36v2) in female breast cancer patients remains unknown. This study aimed to test the reliability, validity, and sensitivity of the Chinese SF-36v2 in women with breast cancer. METHODS: The sample included 326 eligible participants. The reliability and the item convergent and discriminant validity were estimated using Cronbach α (≥0.70) and the multi-trait multi-item matrix analysis, respectively...
December 12, 2018: Journal of Evaluation in Clinical Practice
Esther J Kim, Alexander B Aria, Kelly Wilmas, Daniel J Lewis, Carlos A Torres-Cabala, Cesar Nunez, Bouthaina S Dabaja, Madeleine Duvic
Primary cutaneous CD4+ small- to medium-sized pleomorphic T-cell lymphoproliferative disorder (PCSM-LPD) is a rare and low-grade form of cutaneous T-cell proliferation with the average age of diagnosis of 54 years. Because of its rarity, the etiology or exact clinicopathology of PCSM-LPD remains unclear, with < 10 pediatric cases reported. A 13-year-old boy presented to our clinic with a raised tumor with PCSM-LPD histology and was successfully treated with ultra-low-dose radiation therapy. While no standard of care has been established for pediatric PCSM-LPD, this report represents an example of achieving remission in a pediatric tumor with minimal potential for therapy-related long-term toxicity...
December 11, 2018: Pediatric Dermatology
Lewis D Blackman, Pathiraja A Gunatillake, Peter Cass, Katherine E S Locock
Zwitterionic polymers, including polyampholytes and polybetaines, are polymers with both positive and negative charges incorporated into their structure. They are a unique class of smart materials with great potential in a broad range of applications in nanotechnology, biomaterials science, nanomedicine and healthcare, as additives for bulk construction materials and crude oil, and in water remediation. In this Tutorial Review, we aim to highlight their structural diversity and design criteria, and their preparation using modern techniques...
December 14, 2018: Chemical Society Reviews
Greg Hapgood, Janey M Stone, Diana Zannino, Anup George, Paula Marlton, Henry Miles Prince, Chi-Hung Hui, Ian Prosser, Ian D Lewis, Kenneth Bradstock, John F Seymour
To improve complete remission (CR) rates by reducing toxicity and enhancing delivery, we created a modified hyper-CVAD/MA regimen (cyclophosphamide, vincristine, doxorubicin, dexamethasone/methotrexate, cytarabine) by reducing the cytarabine dose (3 g/m2 to 2 g/m2 ) and number of cycles (eight to six). We conducted a phase II trial in the pre-rituximab era in the intermediate-high international prognostic index (IPI) (≥2) de novo diffuse large B-cell lymphoma (DLBCL) and peripheral T-cell lymphoma (PTCL) (ACTRN12605000105640)...
December 14, 2018: Leukemia & Lymphoma
A Adare, C Aidala, N N Ajitanand, Y Akiba, M Alfred, V Andrieux, K Aoki, N Apadula, H Asano, C Ayuso, B Azmoun, V Babintsev, M Bai, N S Bandara, B Bannier, K N Barish, S Bathe, A Bazilevsky, M Beaumier, S Beckman, R Belmont, A Berdnikov, Y Berdnikov, D S Blau, M Boer, J S Bok, K Boyle, M L Brooks, J Bryslawskyj, V Bumazhnov, C Butler, S Campbell, V Canoa Roman, R Cervantes, C-H Chen, C Y Chi, M Chiu, I J Choi, J B Choi, T Chujo, Z Citron, M Connors, N Cronin, M Csanád, T Csörgő, T W Danley, A Datta, M S Daugherity, G David, K DeBlasio, K Dehmelt, A Denisov, A Deshpande, E J Desmond, A Dion, P B Diss, D Dixit, J H Do, A Drees, K A Drees, M Dumancic, J M Durham, A Durum, T Elder, A Enokizono, H En'yo, S Esumi, B Fadem, W Fan, N Feege, D E Fields, M Finger, M Finger, S L Fokin, J E Frantz, A Franz, A D Frawley, Y Fukuda, C Gal, P Gallus, P Garg, H Ge, F Giordano, A Glenn, Y Goto, N Grau, S V Greene, M Grosse Perdekamp, T Gunji, H Guragain, T Hachiya, J S Haggerty, K I Hahn, H Hamagaki, H F Hamilton, S Y Han, J Hanks, S Hasegawa, T O S Haseler, K Hashimoto, X He, T K Hemmick, J C Hill, K Hill, A Hodges, R S Hollis, K Homma, B Hong, T Hoshino, N Hotvedt, J Huang, S Huang, K Imai, J Imrek, M Inaba, A Iordanova, D Isenhower, Y Ito, D Ivanishchev, B V Jacak, M Jezghani, Z Ji, J Jia, X Jiang, B M Johnson, V Jorjadze, D Jouan, D S Jumper, S Kanda, J H Kang, D Kapukchyan, S Karthas, D Kawall, A V Kazantsev, J A Key, V Khachatryan, A Khanzadeev, C Kim, D J Kim, E-J Kim, G W Kim, M Kim, M H Kim, B Kimelman, D Kincses, E Kistenev, R Kitamura, J Klatsky, D Kleinjan, P Kline, T Koblesky, B Komkov, D Kotov, S Kudo, B Kurgyis, K Kurita, M Kurosawa, Y Kwon, R Lacey, J G Lajoie, E O Lallow, A Lebedev, S Lee, S H Lee, M J Leitch, Y H Leung, N A Lewis, X Li, X Li, S H Lim, L D Liu, M X Liu, V-R Loggins, S Lökös, K Lovasz, D Lynch, T Majoros, Y I Makdisi, M Makek, M Malaev, A Manion, V I Manko, E Mannel, H Masuda, M McCumber, P L McGaughey, D McGlinchey, C McKinney, A Meles, M Mendoza, W J Metzger, A C Mignerey, D E Mihalik, A Milov, D K Mishra, J T Mitchell, I Mitrankov, G Mitsuka, S Miyasaka, S Mizuno, A K Mohanty, P Montuenga, T Moon, D P Morrison, S I Morrow, T V Moukhanova, T Murakami, J Murata, A Mwai, K Nagai, K Nagashima, T Nagashima, J L Nagle, M I Nagy, I Nakagawa, H Nakagomi, K Nakano, C Nattrass, P K Netrakanti, T Niida, S Nishimura, R Nishitani, R Nouicer, T Novák, N Novitzky, R Novotny, A S Nyanin, E O'Brien, C A Ogilvie, J D Orjuela Koop, J D Osborn, A Oskarsson, G J Ottino, K Ozawa, R Pak, V Pantuev, V Papavassiliou, J S Park, S Park, S F Pate, M Patel, J-C Peng, W Peng, D V Perepelitsa, G D N Perera, D Yu Peressounko, C E PerezLara, J Perry, R Petti, M Phipps, C Pinkenburg, R Pinson, R P Pisani, A Pun, M L Purschke, P V Radzevich, J Rak, B J Ramson, I Ravinovich, K F Read, D Reynolds, V Riabov, Y Riabov, D Richford, T Rinn, S D Rolnick, M Rosati, Z Rowan, J G Rubin, J Runchey, A S Safonov, B Sahlmueller, N Saito, T Sakaguchi, H Sako, V Samsonov, M Sarsour, K Sato, S Sato, B Schaefer, B K Schmoll, K Sedgwick, R Seidl, A Sen, R Seto, P Sett, A Sexton, D Sharma, I Shein, T-A Shibata, K Shigaki, M Shimomura, T Shioya, P Shukla, A Sickles, C L Silva, D Silvermyr, B K Singh, C P Singh, V Singh, M J Skoby, M Slunečka, K L Smith, M Snowball, R A Soltz, W E Sondheim, S P Sorensen, I V Sourikova, P W Stankus, M Stepanov, S P Stoll, T Sugitate, A Sukhanov, T Sumita, J Sun, Z Sun, S Suzuki, S Syed, J Sziklai, A Takeda, A Taketani, K Tanida, M J Tannenbaum, S Tarafdar, A Taranenko, G Tarnai, R Tieulent, A Timilsina, T Todoroki, M Tomášek, C L Towell, R Towell, R S Towell, I Tserruya, Y Ueda, B Ujvari, H W van Hecke, S Vazquez-Carson, J Velkovska, M Virius, V Vrba, N Vukman, X R Wang, Z Wang, Y Watanabe, Y S Watanabe, F Wei, A S White, C P Wong, C L Woody, M Wysocki, B Xia, C Xu, Q Xu, L Xue, S Yalcin, Y L Yamaguchi, H Yamamoto, A Yanovich, P Yin, J H Yoo, I Yoon, H Yu, I E Yushmanov, W A Zajc, A Zelenski, S Zharko, S Zhou, L Zou
Asymmetric nuclear collisions of p+Al, p+Au, d+Au, and ^{3}He+Au at sqrt[s_{NN}]=200  GeV provide an excellent laboratory for understanding particle production, as well as exploring interactions among these particles after their initial creation in the collision. We present measurements of charged hadron production dN_{ch}/dη in all such collision systems over a broad pseudorapidity range and as a function of collision multiplicity. A simple wounded quark model is remarkably successful at describing the full data set...
November 30, 2018: Physical Review Letters
Xiang-Long Qu, Bing Yan
A novel three-dimensional microporous framework, [Tb(pddb)phen(ox)0.5 ] n (Tb-MOF), was synthesized hydrothermally with V-shaped 4,4'-(pyridine-2,6-diyl)dibenzoic acid (H2 pddb), oxalate (ox), and 1,10-phenanthroline (phen). The framework of Tb-MOF features one-dimensional channels functionalized with pyridine-N Lewis base groups and the absence of coordinated and lattice water molecules in the structure. The Tb-MOF exhibits high thermostability (up to 385 °C) and chemical stability in a wide pH range (4-11) and common organic solvents as well as boiling water...
December 14, 2018: Inorganic Chemistry
Nicole E Arsenault, Zhen Xu, Michael O Wolf
Metal-functionalized flexible Lewis pair (flexLP) complexes are described. Platinum(II) terpyridine (Pt-tpy) units added to a flexLP backbone through copper(I)-catalyzed coupling reactions yield monometallic (1) and bimetallic (2) Pt-tpy flexLP complexes. NMR and UV-vis absorption studies demonstrate that the complexes switch between the open unbound Lewis pair and closed Lewis adduct with solvents of varying hydrogen-bond-donating (HBD) strength as well as varying temperature. The charge-transfer (CT) energies of the complexes can be tuned by controlling the equilibrium between open and closed forms, demonstrating the ability to alter the photophysical behavior of the metal complexes by stimuli-responsive flexLP ligands...
December 14, 2018: Inorganic Chemistry
Jeffrey L Van Eps, Anuj Chaudhry, Joseph S Fernandez-Moure, Christian Boada, Vishwanath Chegireddy, Fernando J Cabrera, Songyuan Tang, Ennio Tasciotti, Raffaella Righetti
BACKGROUND: Complications of ventral hernia repair (VHR) may be investigated by computed tomography or ultrasound (US) but neither modality gives a quantifiable metric of repair quality short of identifying hernia recurrence. Platelet-rich plasma (PRP), a growth factor-rich autologous blood product, has been shown to improve incorporation of native tissue with bioprosthetics. In this study, we investigate the effect of PRP on the incorporation and mechanical integrity of a non-crosslinked porcine acellular dermal matrix (pADM) in a rodent model of VHR and the correlative ability of ultrasound shear wave elastography (US-SWE) to assess repair quality...
December 13, 2018: Surgical Endoscopy
Lauren Lewis, Beth Dolph, Meriem Said, Thomas H Feeley, Liise K Kayler
BACKGROUND: Racial disparities in access to kidney transplantation (KTX) among African Americans (AAs) have been attributed in part to insufficient patient education. Interventions are needed to provide AAs with culturally sensitive, understandable information that increases their capacity to pursue KTX. Research about the factors that activated patients to pursue KTX is necessary to inform such interventions; however, few studies have yielded this type of information. METHODS: We conducted focus groups and one-on-one interviews with 26 AA referred, listed, or transplanted patients and 3 nephrologists to explore decisional factors that foster pursuit of KTX...
December 13, 2018: Journal of Racial and Ethnic Health Disparities
Thomas C Erren, Philip Lewis
Circadian disruption (CD) was implicated in chains of cancer causation when the International Agency for Research on Cancer classified shift-work involving circadian disruption as probably carcinogenic in 2007. In the following decade, epidemiological studies into causal concepts associated with circadian disruption were inconclusive. Unappreciated complexity with an exclusive focus on shift-work, light-at-night, sleep, and melatonin in regard to circadian disruption may be accountable. With compelling non-epidemiological evidence, we posit that ubiquitous circadian disruption causes cancer and, moreover, that this is unexplored epidemiologically...
December 13, 2018: European Journal of Epidemiology
Natalie Shoham, Gemma Lewis, Graziella Favarato, Claudia Cooper
PURPOSE: Anxiety disorders are common. Prevalence is likely to be raised in people with hearing impairment, who experience higher rates of associated risk factors. We conducted, to our knowledge, the first systematic review of the prevalence and correlates of anxiety in people with hearing impairment. METHODS: We searched electronic databases and references of included studies, using predetermined criteria to retrieve original research reporting prevalence of anxiety disorders or symptoms in adult, hearing impaired populations...
December 13, 2018: Social Psychiatry and Psychiatric Epidemiology
Koshiro Nakamura, Akihito Okuda, Kiyotaka Ohta, Hitoshi Matsubara, Kazu Okumura, Kana Yamamoto, Ryosuke Itagaki, Satoshi Suganuma, Etsushi Tsuji, Naonobu Katada
Cobalt-loaded MFI zeolite showed distinct activity for direct methylation of benzene with methane into toluene. High activity was found at around 0.6 of Co/Al molar ratio. Incorporation of carbon from methane into the methyl group of toluene was confirmed with isotope tracer experiments and mass spectroscopy. Ammonia infrared-mass spectroscopy temperature-programmed desorption, transmission electron microscopy, X-ray absorption near edge spectroscopy and extended X-ray absorption fine structure indicated that Lewis acidic divalent (+II of oxidation state) Co species mono-atomically dispersed on the ion exchange site of MFI zeolite was the active species...
September 7, 2018: ChemCatChem
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