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Benoît Lamarche

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https://www.readbyqxmd.com/read/30261125/separate-effects-of-exercise-amount-and-intensity-on-adipose-tissue-and-skeletal-muscle-mass-in-adults-with-abdominal-obesity
#1
Theresa E Cowan, Andrea M Brennan, Paula J Stotz, John Clarke, Benoit Lamarche, Robert Ross
OBJECTIVE: To determine the effects of exercise amount (kilocalories per session) and intensity (percent of maximal oxygen consumption [% VO2 peak]) on adipose tissue (AT) and skeletal muscle (SM) in adults with abdominal obesity. METHODS: Participants (n = 103; 52.7 ± 7.6 years) were randomized to the following groups: control; low-amount, low-intensity exercise (180 kcal/session [women] and 300 kcal/session [men] at 50% VO2 peak); high-amount, low-intensity exercise (HALI; 360 kcal/session [women] and 600 kcal/session [men] at 50% VO2 peak); or high-amount, high-intensity exercise (HAHI; 360 kcal/session [women] and 600 kcal/session [men] at 75% VO2 peak) for 24 weeks...
September 27, 2018: Obesity
https://www.readbyqxmd.com/read/30217199/development-and-validation-of-a-dietary-screener-for-carbohydrate-intake-in-endurance-athletes
#2
Stéphanie Harrison, Élise Carbonneau, Denis Talbot, Simone Lemieux, Benoît Lamarche
BACKGROUND: Studies have shown that the majority of endurance athletes do not achieve the minimal recommended carbohydrate (CHO) intake of 6 g/kg of body weight (BW), with potentially negative impacts on recovery and performance. The purpose of this study was to develop and validate a rapid and easy to use dietary screener to identify athletes who do and do not achieve a CHO intake > 6 g/kg BW in the context of endurance sports. METHODS: The dietary screener was developed using multiple logistic regression modeling of data from a sample of 1571 non-athlete adults (826 women and 745 men, mean age 44...
September 14, 2018: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/30216237/individual-variability-in-waist-circumference-and-body-weight-in-response-to-exercise
#3
Brittany P Hammond, Paula J Stotz, Andrea M Brennan, Benoît Lamarche, Andrew G Day, Robert Ross
PURPOSE: To determine the magnitude of exercise-induced individual variability for waist circumference (WC) and body weight change after accounting for biological variability and measurement error. Determinants of response variability were also considered. METHODS: Participants (53 ± 7.5 years) were 181 (61% women) adults with abdominal obesity randomized to: control; low amount, low intensity (LALI); high amount, low intensity (HALI); or high amount, high intensity exercise (HAHI) for 24 weeks...
September 14, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/30213092/comparing-interviewer-administered-and-web-based-food-frequency-questionnaires-to-predict-energy-requirements-in-adults
#4
Didier Brassard, Simone Lemieux, Amélie Charest, Annie Lapointe, Patrick Couture, Marie-Ève Labonté, Benoît Lamarche
Traditional food frequency questionnaires (FFQs) are influenced by systematic error, but web-based FFQ (WEB-FFQs) may mitigate this source of error. The objective of this study was to compare the accuracy of interview-based and web-based FFQs to assess energy requirements (mERs). The mER was measured in a series of controlled feeding trials in which participants daily received all foods and caloric drinks to maintain stable body weight over 4 to 6 weeks. FFQs assessing dietary intakes and hence mean energy intake were either interviewer-administered by a registered dietitian (IA-FFQ, n = 127; control method) or self-administered using a web-based platform (WEB-FFQ, n = 200; test method), on a single occasion...
September 12, 2018: Nutrients
https://www.readbyqxmd.com/read/30195246/relative-validity-of-a-web-based-self-administered-24-h-dietary-recall-to-evaluate-adherence-to-canadian-dietary-guidelines
#5
Jacynthe Lafrenière, Catherine Laramée, Julie Robitaille, Benoît Lamarche, Simone Lemieux
OBJECTIVES: A new, web-based, 24-h recall (R24 W) was developed and programmed to assess adherence to Canadian dietary guidelines by automatically generating the Canadian Healthy Eating Index 2007 (C-HEI 2007). The aim of the present study was to determine the relative validity of the R24 W in terms of its ability to generate C-HEI 2007 scores that match those derived from a food record (FR). METHODS: A total of 57 women and 50 men filled a 3-d FR and three 24-h food recalls with the R24 W...
May 24, 2018: Nutrition
https://www.readbyqxmd.com/read/30065355/assessing-the-impact-of-the-diet-on-cardiometabolic-outcomes-are-multiple-measurements-post-intervention-necessary
#6
Janie Allaire, Denis Talbot, Patrick Couture, André Tchernof, Peter J H Jones, Penny Kris-Etherton, Sheila G West, Philip W Connelly, David J A Jenkins, Benoît Lamarche
The purpose of this study was to examine how using the mean of two consecutive measurements vs. one measurement post-treatment influences the sample size required to detect changes in cardiometabolic risk factors in dietary studies. For a given statistical power, using the mean of two measurements taken on consecutive days post-treatment instead of a single measurement significantly reduces the sample size required to observe changes in triglyceride, total apolipoprotein B100, and C-reactive protein concentrations in the context of a supplementation study...
July 31, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/30065157/genetic-and-common-environmental-contributions-to-familial-resemblances-in-plasma-carotenoid-concentrations-in-healthy-families
#7
Bénédicte L Tremblay, Frédéric Guénard, Benoît Lamarche, Louis Pérusse, Marie-Claude Vohl
Carotenoids have shown an interindividual variability that may be due to genetic factors. The only study that has reported heritability of serum α- and β-carotene has not considered the environmental component. This study aimed to estimate the contribution of both genetic and common environmental effects to the variance of carotenoid concentrations and to test whether their phenotypic correlations with cardiometabolic risk factors are explained by shared genetic and environmental effects. Plasma carotenoid concentrations (α-carotene, β-carotene, β-cryptoxanthin, lutein, lycopene, zeaxanthin, and total carotenoids) of 48 healthy subjects were measured...
July 31, 2018: Nutrients
https://www.readbyqxmd.com/read/30053283/diets-low-in-saturated-fat-with-different-unsaturated-fatty-acid-profiles-similarly-increase-serum-mediated-cholesterol-efflux-from-thp-1-macrophages-in-a-population-with-or-at-risk-for-metabolic-syndrome-the-canola-oil-multicenter-intervention-trial
#8
Xiaoran Liu, Josephine Garban, Peter J Jones, Jack Vanden Heuvel, Benoît Lamarche, David J Jenkins, Philip W Connelly, Patrick Couture, Shuaihua Pu, Jennifer A Fleming, Sheila G West, Penny M Kris-Etherton
Background: Cholesterol efflux plays an important role in preventing atherosclerosis progression. Vegetable oils with varying unsaturated fatty acid profiles favorably affect multiple cardiovascular disease risk factors; however, their effects on cholesterol efflux remain unclear. Objective: The objectives of this study were to examine the effects of diets low in saturated fatty acids (SFAs) with varying unsaturated fatty acid profiles on serum-mediated cholesterol efflux and its association with the plasma lipophilic index and central obesity...
May 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29976261/assessing-the-relative-validity-of-a-new-web-based-self-administered-24-h-dietary-recall-in-a-french-canadian-population
#9
Jacynthe Lafrenière, Catherine Laramée, Julie Robitaille, Benoît Lamarche, Simone Lemieux
OBJECTIVE: To assess the relative validity of a new, web-based, self-administered 24 h dietary recall, the R24W, for assessment of energy and nutrient intakes among French Canadians. DESIGN: Each participant completed a 3d food record (FR) and the R24W on three occasions over a 4-week period. Intakes of energy and of twenty-four selected nutrients assessed by both methods were compared. SETTING: Québec City metropolitan area. SUBJECTS: Fifty-seven women and fifty men (mean (sd) age: 47·2 (13·3) years)...
October 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29946054/plasma-pcsk9-correlates-with-apob-48-containing-triglyceride-rich-lipoprotein-production-in-men-with-insulin-resistance
#10
Jean-Philippe Drouin-Chartier, André J Tremblay, Jean-Charles Hogue, Valéry Lemelin, Benoît Lamarche, Patrick Couture
Intestinal triglyceride (TG)-rich lipoproteins (TRLs) are important in the pathogenesis of atherosclerosis in insulin resistance (IR). We investigated the association of plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) concentrations with apoB-48-containing TRL metabolism in 148 men displaying various degrees of IR by measuring in vivo kinetics of TRL apoB-48 during a constant-fed state after a primed-constant infusion of L-[5,5,5-D3]leucine. Plasma PCSK9 concentrations positively correlated with TRL apoB-48 pool size ( r = 0...
August 2018: Journal of Lipid Research
https://www.readbyqxmd.com/read/29920211/the-combination-of-single-nucleotide-polymorphisms-rs6720173-abcg5-rs3808607-cyp7a1-and-rs760241-dhcr7-is-associated-with-differing-serum-cholesterol-responses-to-dairy-consumption
#11
Mohammad M H Abdullah, Peter K Eck, Patrick Couture, Benoît Lamarche, Peter J H Jones
Existing evidence on the influence of genetic architecture on serum cholesterol responsiveness to dietary interventions focuses on individual single nucleotide polymorphisms and single nutrients. We associated the combination of ABCG5 rs6720173-C, CYP7A1 rs3808607-TT, and DHCR7 rs760241-GG genotypes with lower low-density lipoprotein cholesterol concentrations relative to the combination of rs6720173-GG, rs3808607-G, and rs760241-A genotypes (-0.37 ± 0.12 (n = 9) vs. +0.38 ± 0.14 mmol/L (n = 7), p = 0.0016) following a blended dairy (3 servings/day for 4 weeks) intervention...
October 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29846653/high-dose-dha-has-more-profound-effects-on-ldl-related-features-than-high-dose-epa-the-compared-study
#12
Janie Allaire, Cécile Vors, André J Tremblay, Johanne Marin, Amélie Charest, André Tchernof, Patrick Couture, Benoît Lamarche
Context: Supplementation with high-dose docosahexaenoic acid (DHA) increases serum low-density lipoprotein (LDL) cholesterol (LDL-C) concentrations more than high-dose eicosapentaenoic acid (EPA). The mechanisms underlying this difference are unknown. Objective: To examine the phenotypic change in LDL and mechanisms responsible for the differential LDL-C response to EPA and DHA supplementation in men and women at risk of cardiovascular disease. Design, Setting, Participants, and Intervention: In a double-blind, controlled, crossover study, 48 men and 106 women with abdominal obesity and subclinical inflammation were randomized to a sequence of three treatment phases: phase 1, 2...
August 1, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29804555/social-support-for-healthy-eating-development-and-validation-of-a-questionnaire-for-the-french-canadian-population
#13
Elise Carbonneau, Maude Bradette-Laplante, Benoît Lamarche, Véronique Provencher, Catherine Bégin, Julie Robitaille, Sophie Desroches, Marie-Claude Vohl, Louise Corneau, Simone Lemieux
OBJECTIVE: The present study aimed to develop and validate a questionnaire assessing social support for healthy eating in a French-Canadian population. DESIGN: A twenty-one-item questionnaire was developed. For each item, participants were asked to rate the frequency, in the past month, with which the actions described had been done by family and friends in two different environments: (i) at home and (ii) outside of home. The content was evaluated by an expert panel...
September 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29789878/nuts-as-a-replacement-for-carbohydrates-in-the-diabetic-diet-a-reanalysis-of-a-randomised-controlled-trial
#14
David J A Jenkins, Cyril W C Kendall, Benoît Lamarche, Monica S Banach, Korbua Srichaikul, Edward Vidgen, Sandy Mitchell, Tina Parker, Stephanie Nishi, Balachandran Bashyam, Russell J de Souza, Christopher Ireland, Sathish C Pichika, Joseph Beyene, John L Sievenpiper, Robert G Josse
AIMS/HYPOTHESIS: In line with current advice, we assessed the effect of replacing carbohydrate consumption with mixed nut consumption, as a source of unsaturated fat, on cardiovascular risk factors and HbA1c in type 2 diabetes. The data presented here are from a paper that was retracted at the authors' request ( https://doi.org/10.2337/dc16-rt02 ) owing to lack of adjustment for repeated measures in the same individual. Our aim, therefore, was to fix the error and add new complementary data of interest, including information on clotting factors and LDL particle size...
August 2018: Diabetologia
https://www.readbyqxmd.com/read/29703154/familial-resemblances-in-human-whole-blood-transcriptome
#15
Bénédicte L Tremblay, Frédéric Guénard, Benoît Lamarche, Louis Pérusse, Marie-Claude Vohl
BACKGROUND: Considering the implication of gene expression in the susceptibility of chronic diseases and the familial clustering of chronic diseases, the study of familial resemblances in gene expression levels is then highly relevant. Few studies have considered the contribution of both genetic and common environmental effects to familial resemblances in whole blood gene expression levels. The objective is to quantify the contribution of genetic and common environmental effects in the familial resemblances of whole blood genome-wide gene expression levels...
April 27, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29698057/differential-associations-between-plasma-concentrations-of-insulin-and-glucose-and-intestinal-expression-of-key-genes-involved-in-chylomicron-metabolism
#16
Jean-Philippe Drouin-Chartier, André J Tremblay, Valéry Lemelin, Benoît Lamarche, Patrick Couture
The mechanisms underlying the oversecretion of apolipoprotein (apo)B-48-containing triglyceride-rich lipoproteins (TRL) in insulin-resistance (IR) states in humans remain to be fully understood. The objective of this study was to evaluate the association between the plasma levels of insulin and glucose and the intestinal expression of key genes involved in chylomicron metabolism in a large sample of nondiabetic men displaying various degrees of IR. Duodenal biopsies were obtained by gastroduodenoscopy in 127 men free of intestinal disease...
August 1, 2018: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29659963/saturated-fats-from-butter-but-not-from-cheese-increase-hdl-mediated-cholesterol-efflux-capacity-from-j774-macrophages-in-men-and-women-with-abdominal-obesity
#17
Didier Brassard, Benoît J Arsenault, Marjorie Boyer, Daniela Bernic, Maude Tessier-Grenier, Denis Talbot, Angelo Tremblay, Emile Levy, Bela Asztalos, Peter J H Jones, Patrick Couture, Benoît Lamarche
Background: Recent evidence suggests that the association between dietary saturated fatty acids (SFAs) and coronary artery disease risk varies according to food sources. How SFAs from butter and cheese influence HDL-mediated cholesterol efflux capacity (CEC), a key process in reverse cholesterol transport, is currently unknown. Objective: In a predefined secondary analysis of a previously published trial, we have examined how diets rich in SFAs from either cheese or butter influence HDL-mediated CEC, compared with diets rich in either monounsaturated fatty acids (MUFAs) or polyunsaturated fatty acids (PUFAs)...
April 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29546309/supplementation-with-resveratrol-and-curcumin-does-not-affect-the-inflammatory-response-to-a-high-fat-meal-in-older-adults-with-abdominal-obesity-a-randomized-placebo-controlled-crossover-trial
#18
Cécile Vors, Charles Couillard, Marie-Eve Paradis, Iris Gigleux, Johanne Marin, Marie-Claude Vohl, Patrick Couture, Benoît Lamarche
Background: High-fat meals induce postprandial inflammation. Resveratrol is a polyphenol known to prevent comorbidities associated with cardiovascular disease and exerts an anti-inflammatory action. There is also an increasing body of evidence supporting the role of curcumin, a polyphenol from the curcuminoid family, as a modulator of proinflammatory processes. Objective: The objectives of this study were to investigate the following: 1) the bioavailability of resveratrol consumed in combination with curcumin after consumption of a high-fat meal; and 2) the acute combined effects of this combination on the postprandial inflammatory response of subjects with abdominal obesity...
March 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29407885/high-serum-triglyceride-concentrations-in-patients-with-homozygous-familial-hypercholesterolemia-attenuate-the-efficacy-of-lipoprotein-apheresis-by-dextran-sulfate-adsorption
#19
Jean-Philippe Drouin-Chartier, André J Tremblay, Jean Bergeron, Benoît Lamarche, Patrick Couture
BACKGROUND AND AIMS: Maximizing the acute reduction of LDL-cholesterol (C) and lipoprotein (a) (Lp(a)) concentrations in patients with homozygous familial hypercholesterolemia (HoFH) is the main goal of lipoprotein apheresis (LA). The objective of this study was to examine how the pre-LA serum TG concentrations influence the efficacy of LA to acutely reduce LDL-C and Lp(a) concentrations in HoFH patients. METHODS: Data from 1761 LA treatments of HoFH patients (n = 10) and compound heterozygous patients (n = 5) collected between 2008 and 2016 were analyzed...
March 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29381796/substitution-of-dietary-%C3%AF-6-polyunsaturated-fatty-acids-for-saturated-fatty-acids-decreases-ldl-apolipoprotein-b-100-production-rate-in-men-with-dyslipidemia-associated-with-insulin-resistance-a-randomized-controlled-trial
#20
Jean-Philippe Drouin-Chartier, André J Tremblay, Marie-Claude Lépine, Valéry Lemelin, Benoît Lamarche, Patrick Couture
Background: The substitution of omega (ω)-6 (n-6) polyunsaturated fatty acids (PUFAs) for saturated fatty acids (SFAs) is advocated in cardiovascular disease prevention. The impact of this substitution on lipoprotein metabolism in subjects with dyslipidemia associated with insulin resistance (IR) remains unknown. Objective: In men with dyslipidemia and IR, we evaluated the impact of substituting ω-6 PUFAs for SFAs on the in vivo kinetics of apolipoprotein (apo) B-containing lipoproteins and on the intestinal expression of key genes involved in lipoprotein metabolism...
January 1, 2018: American Journal of Clinical Nutrition
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