keyword
https://read.qxmd.com/read/36227828/deep-learning-based-image-registration-in-dynamic-myocardial-perfusion-ct-imaging
#21
JOURNAL ARTICLE
A Lara-Hernandez, T Rienmuller, I Juarez, M Perez, F Reyna, D Baumgartner, V N Makarenko, O L Bockeria, M Maksudov, R Rienmuller, C Baumgartner
Registration of dynamic CT image sequences is a crucial preprocessing step for clinical evaluation of multiple physiological determinants in the heart such as global and regional myocardial perfusion. In this work, we present a deformable deep learning-based image registration method for quantitative myocardial perfusion CT examinations, which in contrast to previous approaches, takes into account some unique challenges such as low image quality with less accurate anatomical landmarks, dynamic changes of contrast agent concentration in the heart chambers and tissue, and misalignment caused by cardiac stress, respiration, and patient motion...
October 13, 2022: IEEE Transactions on Medical Imaging
https://read.qxmd.com/read/35926953/dynamic-simulation-of-aortic-valve-stenosis-using-a-lumped-parameter-cardiovascular-system-model-with-flow-regime-dependent-valve-pressure-loss-characteristics
#22
JOURNAL ARTICLE
Ryno Laubscher, Johan van der Merwe, Jacques Liebenberg, Philip Herbst
Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and obstructive lesions on the valve body can assist clinicians in preparing personalised treatments. In the present work, a multi-compartment lumped parameter model of the human cardiovascular system is developed, with a newly proposed valve modelling approach which accounts for geometry and flow regime dependent pressure drops along with the valve cusp motion...
August 2022: Medical Engineering & Physics
https://read.qxmd.com/read/35646225/dynaring-a-patient-specific-mitral-annuloplasty-ring-with-selective-stiffness-segments
#23
JOURNAL ARTICLE
Samuel Frishman, Ali Kight, Ileana Pirozzi, Sainiteesh Maddineni, Annabel M Imbrie-Moore, Zulekha Karachiwalla, Michael J Paulsen, Alexander D Kaiser, Y Joseph Woo, Mark R Cutkosky
Annuloplasty ring choice and design are critical to the long-term efficacy of mitral valve (MV) repair. DynaRing is a selectively compliant annuloplasty ring composed of varying stiffness elastomer segments, a shape-set nitinol core, and a cross diameter filament. The ring provides sufficient stiffness to stabilize a diseased annulus while allowing physiological annular dynamics. Moreover, adjusting elastomer properties provides a mechanism for effectively tuning key MV metrics to specific patients. We evaluate the ring embedded in porcine valves with an ex-vivo left heart simulator and perform a 150 million cycle fatigue test via a custom oscillatory system...
September 1, 2022: Journal of Medical Devices
https://read.qxmd.com/read/35567886/congenital-supravalvular-aortic-stenosis-in-a-kitten
#24
JOURNAL ARTICLE
V Szatmári
A three-month-old, male intact Norwegian forest cat without any clinical signs was referred to the cardiology service of the author's teaching hospital for evaluation of a cardiac murmur. The murmur was systolic with an intensity of 4 out of 6 with the point of maximal intensity at the left heart base. Echocardiography revealed a moderate mitral valve regurgitation and a moderate dynamic left ventricular outflow tract obstruction both resulting from systolic anterior motion of the mitral valve (SAM). Moreover, left ventricular concentric hypertrophy was noted...
June 2022: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://read.qxmd.com/read/35464518/a-rare-presentation-of-systolic-anterior-motion-occurring-eight-years-after-mitral-valve-replacement
#25
Olushola O Ogunleye, Hussain Dalal, Khalid Mahmood, Siyamek Neragi-Miandoab, Aarti Campo
Systolic anterior motion (SAM) is the dynamic displacement of mitral valve leaflets anteriorly toward the left ventricular outflow tract (LVOT) during systole. SAM-like physiology has been reported to occur shortly after mitral valve replacement (MVR) surgery; occurrence beyond two years after surgery is very rare. A 55-year-old woman who had bioprosthetic MVR eight years earlier for non-rheumatic mitral stenosis presented to the emergency room with progressive dyspnea and sudden-onset chest pressure. Physical examination noted a grade 3/6 systolic murmur at the cardiac apex, a soft diastolic murmur at the left sternal border, and diffuse expiratory wheezing...
March 2022: Curēus
https://read.qxmd.com/read/35391837/ct-based-simulation-of-left-ventricular-hemodynamics-a-pilot-study-in-mitral-regurgitation-and-left-ventricle-aneurysm-patients
#26
JOURNAL ARTICLE
Lukas Obermeier, Katharina Vellguth, Adriano Schlief, Lennart Tautz, Jan Bruening, Christoph Knosalla, Titus Kuehne, Natalia Solowjowa, Leonid Goubergrits
Background: Cardiac CT (CCT) is well suited for a detailed analysis of heart structures due to its high spatial resolution, but in contrast to MRI and echocardiography, CCT does not allow an assessment of intracardiac flow. Computational fluid dynamics (CFD) can complement this shortcoming. It enables the computation of hemodynamics at a high spatio-temporal resolution based on medical images. The aim of this proposed study is to establish a CCT-based CFD methodology for the analysis of left ventricle (LV) hemodynamics and to assess the usability of the computational framework for clinical practice...
2022: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/35322461/retrospective-evaluation-of-hypertrophic-cardiomyopathy-in-68-dogs
#27
MULTICENTER STUDY
Karsten E Schober, Phillip R Fox, Jonathan Abbott, Etienne Côté, Virginia Luis-Fuentes, Jose Novo Matos, Joshua A Stern, Lance Visser, Katherine F Scollan, Valerie Chetboul, Donald Schrope, Tony Glaus, Roberto Santilli, Romain Pariaut, Rebecca Stepien, Vanessa Arqued-Soubeyran, Marco Baron Toaldo, Amara Estrada, Kristin MacDonald, Emily T Karlin, John Rush
BACKGROUND: There is a lack of clinical data on hypertrophic cardiomyopathy (HCM) in dogs. HYPOTHESIS/OBJECTIVES: To investigate signalment, clinical signs, diagnostic findings, and survival in dogs with HCM. ANIMALS: Sixty-eight client-owned dogs. METHODS: Retrospective multicenter study. Medical records were searched between 2003 and 2015. The diagnosis of left ventricular (LV) hypertrophy was made by echocardiographic examination...
May 2022: Journal of Veterinary Internal Medicine
https://read.qxmd.com/read/34917710/an-in-silico-benchmark-for-the-tricuspid-heart-valve-geometry-finite-element-mesh-abaqus-simulation-and-result-data-set
#28
JOURNAL ARTICLE
Devin W Laurence, Chung-Hao Lee, Emily L Johnson, Ming-Chen Hsu
This article provides Abaqus input files and user subroutines for performing finite element simulations of the tricuspid heart valve with an idealized geometry. Additional post-processing steps to obtain a ParaView visualization file (*.vtk) of the deformed geometry are also provided to allow the readers to use the included ParaView state file (*.pvsm) for customizable visualization and evaluation of the simulation results. We expect this first-of-its-kind in-silico benchmark dataset will facilitate user-friendly simulations considering material nonlinearity, leaflet-to-leaflet contact, and large deformations...
December 2021: Data in Brief
https://read.qxmd.com/read/34693811/the-feline-cardiomyopathies-2-hypertrophic-cardiomyopathy
#29
JOURNAL ARTICLE
Mark D Kittleson, Etienne Côté
PRACTICAL RELEVANCE: Hypertrophic cardiomyopathy (HCM) is the most common form of feline cardiomyopathy observed clinically and may affect up to approximately 15% of the domestic cat population, primarily as a subclinical disease. Fortunately, severe HCM, leading to heart failure or arterial thromboembolism (ATE), only occurs in a small proportion of these cats. PATIENT GROUP: Domestic cats of any age from 3 months upward, of either sex and of any breed, can be affected...
November 2021: Journal of Feline Medicine and Surgery
https://read.qxmd.com/read/34690809/detecting-aortic-valve-anomaly-from-induced-murmurs-insights-from-computational-hemodynamic-models
#30
JOURNAL ARTICLE
Shantanu Bailoor, Jung-Hee Seo, Stefano Schena, Rajat Mittal
Patients who receive transcatheter aortic valve replacement are at risk for leaflet thrombosis-related complications, and can benefit from continuous, longitudinal monitoring of the prosthesis. Conventional angiography modalities are expensive, hospital-centric and either invasive or employ potentially nephrotoxic contrast agents, which preclude their routine use. Heart sounds have been long recognized to contain valuable information about individual valve function, but the skill of auscultation is in decline due to its heavy reliance on the physician's proficiency leading to poor diagnostic repeatability...
2021: Frontiers in Physiology
https://read.qxmd.com/read/34460941/video-based-valve-motion-combined-with-computational-fluid-dynamics-gives-stable-and-accurate-simulations-of-blood-flow-in-the-realheart%C3%A2-total-artificial-heart
#31
JOURNAL ARTICLE
Nathaniel S Kelly, Danny McCree, Libera Fresiello, Nils Brynedal Ignell, Andrew N Cookson, Azad Najar, Ina Laura Perkins, Katharine H Fraser
BACKGROUND: Patients with end-stage, biventricular heart failure, and for whom heart transplantation is not an option, may be given a Total Artificial Heart (TAH). The Realheart® is a novel TAH which pumps blood by mimicking the native heart with translation of an atrioventricular plane. The aim of this work was to create a strategy for using Computational Fluid Dynamics (CFD) to simulate haemodynamics in the Realheart®, including motion of the atrioventricular plane and valves. METHODS: The accuracies of four different computational methods for simulating fluid-structure interaction of the prosthetic valves were assessed by comparison of chamber pressures and flow rates with experimental measurements...
August 30, 2021: Artificial Organs
https://read.qxmd.com/read/34362020/dynamic-left-intraventricular-obstruction-phenotype-in-takotsubo-syndrome
#32
REVIEW
Davide Di Vece, Angelo Silverio, Michele Bellino, Gennaro Galasso, Carmine Vecchione, Giovanni La Canna, Rodolfo Citro
Takotsubo syndrome (TTS) is characterized by acute, generally transient left ventricular (LV) dysfunction. Although TTS has been long regarded as a benign condition, recent evidence showed that rate of acute complications and in-hospital mortality is comparable to that of patients with acute coronary syndrome. In particular, the prevalence of cardiogenic shock ranges between 6% and 20%. In this setting, detection of mechanisms leading to cardiogenic shock can be challenging. Besides a severely impaired systolic function, onset of LV outflow tract obstruction (LVOTO) together with mitral regurgitation related to systolic anterior motion of mitral valve leaflets can lead to hemodynamic instability...
July 22, 2021: Journal of Clinical Medicine
https://read.qxmd.com/read/34149063/a-sharp-interface-lagrangian-eulerian-method-for-rigid-body-fluid-structure-interaction
#33
JOURNAL ARTICLE
E M Kolahdouz, A P S Bhalla, L N Scotten, B A Craven, B E Griffith
This paper introduces a sharp interface method to simulate fluid-structure interaction (FSI) involving rigid bodies immersed in viscous incompressible fluids. The capabilities of this methodology are benchmarked using a range of test cases and demonstrated using large-scale models of biomedical FSI. The numerical approach developed herein, which we refer to as an immersed Lagrangian-Eulerian (ILE) method, integrates aspects of partitioned and immersed FSI formulations by solving separate momentum equations for the fluid and solid subdomains, as in a partitioned formulation, while also using non-conforming discretizations of the dynamic fluid and structure regions, as in an immersed formulation...
October 15, 2021: Journal of Computational Physics
https://read.qxmd.com/read/34064421/multimodality-imaging-of-the-anatomy-of-the-aortic-root
#34
REVIEW
Vera Lucia Paiocchi, Francesco F Faletra, Enrico Ferrari, Susanne Anna Schlossbauer, Laura Anna Leo, Francesco Maisano
The aortic root has long been considered an inert unidirectional conduit between the left ventricle and the ascending aorta. In the classical definition, the aortic valve leaflets (similar to what is perceived for the atrioventricular valves) have also been considered inactive structures, and their motion was thought to be entirely passive-just driven by the fluctuations of ventricular-aortic gradients. It was not until the advent of aortic valve-sparing surgery and of transcatheter aortic valve implantation that the interest on the anatomy of the aortic root again took momentum...
May 4, 2021: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/33914716/regression-of-systolic-anterior-motion-in-progressive-hypertrophic-cardiomyopathy
#35
JOURNAL ARTICLE
Ofir Koren, Scott Ehrenberg, Lev Bloch, Ehud Rozner, Yoav Turgeman, Sari Naddaf
BACKGROUND Systolic anterior motion (SAM) is the dynamic anteriorly directed movement of the anterior mitral valve leaflet during systole toward the left ventricular outflow tract (LVOT). The history of SAM in progressive hypertrophic cardiomyopathy (HCM) is unclear. It is believed that SAM is an irreversible process that progresses as the gradient over the LVOT increases. We present a case where SAM regressed after extensive left atrial (LA) and left ventricle (LV) remodeling in a patient with progressive HCM...
April 29, 2021: American Journal of Case Reports
https://read.qxmd.com/read/33762278/dynamic-left-ventricular-outflow-tract-obstruction-in-takotsubo-cardiomyopathy-resulting-in-cardiogenic-shock
#36
JOURNAL ARTICLE
Paulina M Conradi, Ramon B van Loon, M Louis Handoko
We report a case of a 73-year-old female patient, who was admitted to the coronary care unit due to chest pain, malaise and near syncope. During physical examination, the patient was hypotensive and there were signs of left-sided heart failure and a loud systolic murmur. Echocardiogram showed apical ballooning with dynamic left ventricular outflow tract obstruction, based on systolic anterior motion of the mitral valve with important mitral valve regurgitation. In the acute setting, the cardiogenic shock was treated cautiously with fluid resuscitation and intravenous metoprolol, resulting in direct stabilisation of her haemodynamic condition...
March 24, 2021: BMJ Case Reports
https://read.qxmd.com/read/33717471/aortic-and-mitral-flow-quantification-using-dynamic-valve-tracking-and-machine-learning-prospective-study-assessing-static-and-dynamic-plane-repeatability-variability-and-agreement
#37
JOURNAL ARTICLE
Julio Garcia, Kailey Beckie, Ali F Hassanabad, Alireza Sojoudi, James A White
Background: Blood flow is a crucial measurement in the assessment of heart valve disease. Time-resolved flow using magnetic resonance imaging (4 D flow MRI) can provide a comprehensive assessment of heart valve hemodynamics but it relies in manual plane analysis. In this study, we aimed to demonstrate the feasibility of automate the detection and tracking of aortic and mitral valve planes to assess blood flow from 4 D flow MRI. Methods: In this prospective study, a total of n  = 106 subjects were enrolled: 19 patients with mitral disease, 65 aortic disease patients and 22 healthy controls...
January 2021: JRSM Cardiovascular Disease
https://read.qxmd.com/read/33638029/transcatheter-heart-valve-downstream-fluid-dynamics-in-an-accelerated-evaluation-environment
#38
JOURNAL ARTICLE
Sailahari V Ponnaluri, Steven Deutsch, Michael S Sacks, Keefe B Manning
Transcatheter aortic valve replacements (TAVRs) provide minimally invasive delivery of bioprosthetic heart valves (BHVs) for the treatment of aortic valve disease. While surgical BHVs show efficacy for 8-10 years, long-term TAVR durability remains unknown. Pre-clinical testing evaluates BHV durability in an ISO:5840 compliant accelerated wear tester (AWT), yet, the design and development of AWTs and their accuracy in predicting in vivo performance, is unclear. As a result of limited knowledge on AWT environment and BHV loading, durability assessment of candidate valves remains fundamentally empirical...
February 26, 2021: Annals of Biomedical Engineering
https://read.qxmd.com/read/33598628/haemodynamic-collapse-immediately-after-transcatheter-aortic-valve-implantation-due-to-dynamic-intraventricular-gradient-a-case-report-and-review-of-the-literature
#39
JOURNAL ARTICLE
Nana Endo, Hisao Otsuki, Satoru Domoto, Junichi Yamaguchi
Background: Dynamic intraventricular obstruction after transcatheter aortic valve implantation (TAVI) has been previously reported. There is a risk of haemodynamic collapse in the case of left ventricular outflow tract (LVOT) obstruction due to systolic anterior motion (SAM) of the mitral valve. Case summary: An 83-year-old woman with aortic stenosis (AS) was referred to our hospital for TAVI. Transthoracic echocardiography revealed a severely calcified aortic valve with a peak velocity of 6...
February 2021: European Heart Journal. Case Reports
https://read.qxmd.com/read/33550364/blood-flow-characteristics-after-aortic-valve-neocuspidization-in-paediatric-patients-a-comparison-with-the-ross-procedure
#40
JOURNAL ARTICLE
Aurelio Secinaro, Elena Giulia Milano, Paolo Ciancarella, Matteo Trezzi, Claudio Capelli, Paolo Ciliberti, Enrico Cetrano, Davide Curione, Teresa Pia Santangelo, Carmela Napolitano, Sonia B Albanese, Adriano Carotti
AIMS: The aortic valve (AV) neocuspidization (Ozaki procedure) is a novel surgical technique for AV disease that preserves the natural motion and cardiodynamics of the aortic root. In this study, we sought to evaluate, by 4D-flow magnetic resonance imaging, the aortic blood flow characteristics after AV neocuspidization in paediatric patients. METHODS AND RESULTS: Aortic root and ascending aorta haemodynamics were evaluated in a population of patients treated with the Ozaki procedure; results were compared with those of a group of patients operated with the Ross technique...
February 7, 2021: European Heart Journal Cardiovascular Imaging
keyword
keyword
16707
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.