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https://www.readbyqxmd.com/read/28811093/risk-factors-for-infective-endocarditis-in-children-with-congenital-heart-diseases-a-nationwide-population-based-case-control-study
#1
Li-Chuan Sun, Chih-Cheng Lai, Cheng-Yi Wang, Ya-Hui Wang, Jen-Yu Wang, Yo-Ling Hsu, Yin-Lan Hu, En-Ting Wu, Ming-Tai Lin, Leticia B Sy, Likwang Chen
BACKGROUND: Infective endocarditis (IE) is uncommon in childhood. Its associated epidemiological characteristics in patients with congenital heart disease (CHD) remain unclear. METHODS: The study population included children born in Taiwan during the years 1997 to 2005 who were diagnosed as having CHD before 3years of age. All children were followed up until the end year of 2010, the diagnosis of infective endocarditis, or death. The demographic characteristics of patients with and without IE, the invasive procedures performed during 6months before the index date, the prophylactic antibiotics related to dental procedures, and in-hospital mortality were collected...
August 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28782496/morphological-three-dimensional-analysis-of-papillary-muscles-in-borderline-left-ventricles
#2
Mari N Velasco Forte, Mohamed Nassar, Nick Byrne, Miguel Silva Vieira, Israel V Pérez, Bram Ruijsink, John Simpson, Tarique Hussain
OBJECTIVE: Mitral valve anatomy has a significant impact on potential surgical options for patients with hypoplastic or borderline left ventricle. Papillary muscle morphology is a major component regarding this aspect. The purpose of this study was to use cardiac magnetic resonance to describe the differences in papillary muscle anatomy between normal, borderline, and hypoplastic left ventricles. METHODS: We carried out a retrospective, observational cardiac magnetic resonance study of children (median age 5...
September 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28776389/congenital-aortic-stenosis-treatment-outcomes-in-a-nationwide-survey
#3
Merja Kallio, Otto Rahkonen, Ilkka Mattila, Jaana Pihkala
OBJECTIVE: To evaluate treatment outcomes of pediatric valvar aortic stenosis (AS) in a nationwide follow-up. DESIGN: Balloon aortic valvuloplasty (BAV) has been the preferred treatment for congenital AS in Finland since the year 2000. All children treated due to isolated AS during 2000-2014 were included in this retrospective study. Treatment outcomes were categorized into Optimal: residual gradient  ≤35 mmHg and trivial or no aortic regurgitation (AR), Adequate: gradient ≤35 mmHg with mild AR, or Inadequate: gradient >35 mmHg and/or moderate to severe AR...
August 4, 2017: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/28753736/can-quantity-of-amniotic-fluid-reliably-predict-postnatal-renal-function-in-boys-with-posterior-urethral-valves-a-decision-curve-analysis
#4
Luke Harper, Alice Waubant, Julien Vignes, Sara Amat, Eric Dobremez, Yan Lefevre, Cyril Ferdynus
OBJECTIVE: Prenatal management of male fetuses with suspected posterior urethral valves depends on reliable markers for postnatal long-term renal function. Whether ultrasound parameters, including the presence or absence of oligohydramnios, are reliable remains the subject of debate. We decided to evaluate the reliability of quantity of amniotic fluid to predict postnatal renal function using decision curve analysis (DCA), a method for evaluating the clinical utility of a diagnostic test...
July 28, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28751538/coronary-anatomy-in-children-with-bicuspid-aortic-valves-and-associated-congenital-heart-disease
#5
Wilke M C Koenraadt, Margot M Bartelings, Regina Bökenkamp, Adriana C Gittenberger-de Groot, Marco C DeRuiter, Martin J Schalij, Monique Rm Jongbloed
OBJECTIVE: In patients with bicuspid aortic valve (BAV), coronary anatomy is variable. High take-off coronary arteries have been described, but data are scarce, especially when associated with complex congenital heart disease (CHD). The purpose of this study was to describe coronary patterns in these patients. METHODS: In 84 postmortem heart specimens with BAV and associated CHD, position and height of the coronary ostia were studied and related to BAV morphology...
July 27, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28745221/rheumatic-heart-disease-pathogenesis-and-vaccine
#6
L Guilherme, S Freschi de Barros, K F Köhler, S R Santos, F Morais Ferreira, W R Silva, R Alencar, E Postol, J Kalil
Rheumatic fever (RF) and rheumatic heart disease (RHD) follow untreated S. pyogenes throat infections in children who present susceptible genes that favor the development of autoimmune reactions. In this review, we focus on the genes that confer susceptibility and on the autoimmune reactions that occur due to molecular mimicry between human-tissue proteins and streptococcal M protein. Polyarthritis is the initial manifestation, which can evolve to carditis and severe valve damage; these culminate in rheumatic heart disease (RHD) or Sydenham's chorea, which affects the central nervous system...
July 25, 2017: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/28745124/dysfunction-of-the-foetal-arterial-duct-results-in-a-wide-spectrum-of-cardiovascular-pathology
#7
Marc Gewillig, Stephen C Brown, Mieke Roggen, Benedicte Eyskens, Ruth Heying, Patrice Givron, Bjorn Cools, Luc de Catte
OBJECTIVE: Foetal ductal problems may have various cardiopulmonary consequences. This study aimed to identify the spectrum of ductus arteriosus (DA) dysfunction (closure, constriction, kinking, aneurysm and thrombosis) and the resultant clinical and echocardiographic presentation in foetuses and neonates. METHODS AND RESULTS: This is a retrospective analysis of serial pre- and post-natal data of 27 cases of foetal ductal dysfunction diagnosed at a median gestational age of 33 weeks (range 20-39)...
July 26, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28743383/successful-atrioventricular-valve-repair-improves-long-term-outcomes-in-children-with-unbalanced-atrioventricular-septal-defect
#8
Edward Buratto, Xin Tao Ye, Christian P Brizard, Johann Brink, Yves d'Udekem, Igor E Konstantinov
BACKGROUND: Atrioventricular valve regurgitation is a significant cause of morbidity and mortality in patients with unbalanced atrioventricular septal defect. However, knowledge of the outcomes of atrioventricular valve repair in children with unbalanced atrioventricular septal defect and univentricular physiology is limited. METHODS: We conducted a retrospective review of all patients with unbalanced atrioventricular septal defect treated with single-ventricle palliation who underwent atrioventricular valve surgery at The Royal Children's Hospital...
June 28, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28730981/bartonella-quintana-an-unrecognized-cause-of-infective-endocarditis-in-children-in-ethiopia
#9
Diana Tasher, Alona Raucher-Sternfeld, Akiva Tamir, Michael Giladi, Eli Somekh
Bartonella quintana endocarditis, a common cause of culture-negative endocarditis in adults, has rarely been reported in children. We describe 5 patients 7-16 years of age from Ethiopia with heart defects and endocarditis; 4 cases were caused by infection with B. quintana and 1 by Bartonella of undetermined species. All 5 patients were afebrile and oligosymptomatic, although 3 had heart failure. C-reactive protein was normal or slightly elevated, and erythrocyte sedimentation rate was high. The diagnosis was confirmed by echocardiographic demonstration of vegetations, the presence of high Bartonella IgG titers, and identification of B...
August 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28725923/assessing-3d-t2-fse-sequence-for-identification-of-the-normal-appendix-working-toward-a-single-sequence-mr-appendicitis-protocol
#10
Nattinee Leelakanok, Andrew S Phelps, Matthew A Zapala, Kambrie Kato, Michael Ohliger, Yi Li, Jesse Courtier
PURPOSES: To assess the ability of a single isotropic 3D T2 FSE sequence to identify the normal appendix in children with potential implication as alternative second-line modality in pediatric appendicitis. MATERIALS AND METHODS: Retrospective review of MR abdomino-pelvis or pelvis in children from Oct 2014-Dec 2016 was done. Only exams with 3D T2 FSE sequence performed on a single scanner type were selected. Patients with history of post appendectomy, studies in which field of view did not include ileocecal valve, with technical and protocol errors, or with fat-saturated acquisition were excluded...
July 19, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28712168/justification-for-re-look-cystoscopy-after-posterior-urethral-valve-fulguration
#11
Gul Nawaz, Ijaz Hussain, Shujah Muhammad, Muhammad Imran Jamil, Asad Ur Rehman, Nadeem Iqbal, Saeed Akhter
BACKGROUND: Posterior urethral valve (PUV) is life-threatening congenital anomaly of the urinary tract that results in vesicoureteric reflux, recurrent UTI, voiding dysfunction and renal insufficiency if not treat timely. Endoscopic ablation of posterior urethral valves using cold knife or laser is the current gold standard therapy. Many urologists go for repeat cystoscopy to see residual valve or stricture while others repeat VCUG to measure the posterior to anterior urethral ratio for residual obstruction...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28711964/utility-of-echocardiography-in-detecting-silent-complications-after-pediatric-catheter-ablations
#12
Shahnawaz M Amdani, Salaam Sallaam, Peter P Karpawich, Sanjeev Aggarwal
Although transcatheter arrhythmia ablation (TCA) has been performed in children for over two decades, guidelines for routine use of post-ablation transthoracic echocardiography (TTE) are absent. We sought to determine the efficacy of TTE after apparently uneventful TCA procedures in detecting adverse findings and identify predisposing factors. A retrospective review of clinical and procedural data on patients who underwent TCA for supraventricular arrhythmias from 2000 to 2015 was performed. Pre- and post-ablation TTE data were reviewed...
July 15, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28704916/three-dimensional-echocardiography-in-adult-congenital-heart-disease
#13
REVIEW
Hyun Suk Yang
Congenital heart disease (CHD) is now more common in adults than in children due to improvements in fetal echo, neonatal and pediatric care, and surgical techniques leading to dramatically increased survivability into adulthood. Adult patients with CHD, regardless of prior cardiac surgery, experience further cardiac problems or therapeutic challenges; therefore, a non-invasive, easily accessible echocardiographic examination is an essential follow-up tool. Among echocardiographic modalities, three-dimensional (3D) echocardiography provides better delineation of spatial relationships in complex cardiac geometries and more accurate volumetric information without geometric assumptions...
July 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28700992/natural-history-of-fetal-lower-urinary-tract-obstruction-with-normal-amniotic-fluid-volume-at-initial-diagnosis
#14
Mark P Johnson, Enrico Danzer, Jamie Koh, William Polzin, Chris Harman, Richard O'Shaughnessy, Richard Brown, Michael V Zaretsky
OBJECTIVE: The aim of this study was to define the natural history of lower urinary tract obstruction (LUTO) with normal midgestational amniotic fluid volumes. MATERIALS AND METHODS: We performed a retrospective review of 32 consecutive patients with LUTO with normal midgestational amniotic fluid volume followed at 11 North American Fetal Therapy Network (NAFTNet) centers from August 2007 to May 2012. Normal amniotic fluid volume was defined as an amniotic fluid index (AFI) of ≥9 cm...
July 13, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28679899/intelligent-phonocardiography-for-screening-ventricular-septal-defect-using-time-growing-neural-network
#15
Arash Gharehbaghi, Amir A Sepehri, Maria Lindén, Ankica Babic
This paper presents results of a study on the applicability of the intelligent phonocardiography in discriminating between Ventricular Spetal Defect (VSD) and regurgitation of the atrioventricular valves. An original machine learning method, based on the Time Growing Neural Network (TGNN), is employed for classifying the phonocardiographic recordings collected from the pediatric referrals to a children hospital. 90 individuals, 30 VSD, 30 with the valvular regurgitation, and 30 healthy subjects, participated in the study after obtaining the informed consents...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28666918/urinary-tract-infection-after-retrograde-urethrogram-in-children-a-multicenter-study
#16
Neha R Malhotra, Jared R Green, Cynthia K Rigsby, Jane L Holl, Earl Y Cheng, Emilie K Johnson
INTRODUCTION: The risk of post-procedural urinary tract infection (ppUTI) after retrograde urethrogram (RUG) has not been well quantified. Prophylactic antibiotics may reduce the risk, but must be weighed against the risks of antibiotic resistance. Prior research has shown that this risk is variable after voiding cystourethrogram (0-42% reported ppUTI rate) and appears to be low after urodynamics (0-4.8%) but this risk has not been well documented for patients undergoing RUG. OBJECTIVE: We aimed to (1) describe the rate of ppUTI after RUG, and (2) examine factors associated with use of antibiotics at the time of RUG...
June 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28666489/atresia-of-the-descending-aorta-in-a-young-woman-requiring-bypass-graft
#17
Adcasdc Sadfasdf Dsc, Ammarah Mashhood, Taimur Asif Ali, Saulat Hasnain Fatimi
Congenital aortic atresia is a malformation accounting for 4 - 6% of all congenital heart diseases in children. Left ventricular outflow obstruction due to atresia is common at the aortic valve but rarely has atresia been identified in the descending aorta. We report the case of a 25-year woman who was evaluated for headache and uncontrolled hypertension. CTscan chest showed a short atretic segment in the descending aorta at the isthmus, distal to the takeoff of the subclavian artery. She underwent surgery; a 22 mm Dacron graft was taken and jump graft was placed between the arch of the aorta and the descending aorta, using partial occlusion clamps...
November 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28659821/candidate-gene-resequencing-in-a-large-bicuspid-aortic-valve-associated-thoracic-aortic-aneurysm-cohort-smad6-as-an-important-contributor
#18
Elisabeth Gillis, Ajay A Kumar, Ilse Luyckx, Christoph Preuss, Elyssa Cannaerts, Gerarda van de Beek, Björn Wieschendorf, Maaike Alaerts, Nikhita Bolar, Geert Vandeweyer, Josephina Meester, Florian Wünnemann, Russell A Gould, Rustam Zhurayev, Dmytro Zerbino, Salah A Mohamed, Seema Mital, Luc Mertens, Hanna M Björck, Anders Franco-Cereceda, Andrew S McCallion, Lut Van Laer, Judith M A Verhagen, Ingrid M B H van de Laar, Marja W Wessels, Emmanuel Messas, Guillaume Goudot, Michaela Nemcikova, Alice Krebsova, Marlies Kempers, Simone Salemink, Toon Duijnhouwer, Xavier Jeunemaitre, Juliette Albuisson, Per Eriksson, Gregor Andelfinger, Harry C Dietz, Aline Verstraeten, Bart L Loeys
Bicuspid aortic valve (BAV) is the most common congenital heart defect. Although many BAV patients remain asymptomatic, at least 20% develop thoracic aortic aneurysm (TAA). Historically, BAV-related TAA was considered as a hemodynamic consequence of the valve defect. Multiple lines of evidence currently suggest that genetic determinants contribute to the pathogenesis of both BAV and TAA in affected individuals. Despite high heritability, only very few genes have been linked to BAV or BAV/TAA, such as NOTCH1, SMAD6, and MAT2A...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28655532/surgical-relief-of-left-ventricular-outflow-tract-obstruction-in-adults-with-congenital-aortic-stenosis-and-associated-aortic-annulus-hypoplasia-and-or-subaortic-obstruction
#19
Tanveer Ahmad, Amalan Thuraisingam, Marco Larobina, Peter Skillington
BACKGROUND: In children and adolescents, a Ross/Konno operation is commonly done to both enlarge the aortic root and provide a competent aortic valve with relief of left ventricular outflow tract obstruction (LVOTO). Optimum management is not so straightforward in adults. METHODS: Between 1995 and 2014, 16 patients of mean age 39.4 years (18-57 years) with hypoplastic aortic annulus (AA) measuring 20mm and less, and mean aortic valve/LVOT gradient of 61mmHg (30-70mmHg) presented for surgery...
June 3, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28651802/echocardiographic-diagnosis-surgical-treatment-and-outcomes-of-anomalous-left-coronary-artery-from-the-pulmonary-artery
#20
Shivani G Patel, Michele A Frommelt, Peter C Frommelt, Shelby Kutty, Jonathan W Cramer
BACKGROUND: Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare condition that can be difficult to diagnose by echocardiography alone. The purpose of this study was to describe the clinical and echocardiographic presentation of ALCAPA, create a set of critical echocardiographic diagnostic criteria, and report outcomes. METHODS: A retrospective review was conducted of all patients diagnosed with isolated ALCAPA at two major cardiac centers between 1990 and 2015...
June 23, 2017: Journal of the American Society of Echocardiography
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