Arash Kheradvar, Elliott M Groves, Lakshmi P Dasi, S Hamed Alavi, Robert Tranquillo, K Jane Grande-Allen, Craig A Simmons, Boyce Griffith, Ahmad Falahatpisheh, Craig J Goergen, Mohammad R K Mofrad, Frank Baaijens, Stephen H Little, Suncica Canic
As the first section of a multi-part review series, this section provides an overview of the ongoing research and development aimed at fabricating novel heart valve replacements beyond what is currently available for patients. Here we discuss heart valve replacement options that involve a biological component or process for creation, either in vitro or in vivo (tissue-engineered heart valves), and heart valves that are fabricated from polymeric material that are considered permanent inert materials that may suffice for adults where growth is not required...
April 2015: Annals of Biomedical Engineering