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https://www.readbyqxmd.com/read/30326482/perioperative-hypotensive-crisis-in-an-adolescent-with-a-pancreatic-vipoma-and-men1-gene-variant
#1
Alejandra Acosta-Gualandri, Kung-Ting Kao, Tiffany Wong, Eric Webber, Linlea Armstrong, Constadina Panagiotopoulos
BACKGROUND: Vasoactive intestinal peptide-secreting tumours (VIPomas) lead to high-volume secretory diarrhoea with hypokalaemia, as well as hyperglycaemia and hypercalcaemia. Diagnosis is often delayed. CASE DESCRIPTION: We present a 13-year-old girl with a distal pancreatic VIPoma diagnosed on her second hospital presentation who became severely hypotensive on anaesthetic induction prior to tumour removal, likely due to the vasodilatory effect of supraphysiological VIP levels...
October 16, 2018: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/30323269/smoking-status-at-diagnosis-and-subsequent-smoking-cessation-associations-with-corticosteroid-use-and-intestinal-resection-in-crohn-s-disease
#2
Christopher Alexakis, Sonia Saxena, Vivek Chhaya, Elizabeth Cecil, Azeem Majeed, Richard Pollok
BACKGROUND: The impact of smoking at diagnosis and subsequent smoking cessation on clinical outcomes in Crohn's disease (CD) has not been evaluated in a population-based cohort. METHODS: Using a nationally representative clinical research database, we identified incident cases of CD between 2005 and 2014. We compared the following outcomes: overall corticosteroid (CS) use; flares requiring CS; CS dependency and intestinal surgery between smokers and non-smokers at time of CD diagnosis...
October 15, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/30314526/operative-r0-resection-of-diffuse-large-b-cell-lymphoma-of-the-pelvis-a-case-report
#3
Valerie Wienerroither, Martin Sauerschnig, Christine Beham-Schmid, Erwin Mathew, Azab El-Shabrawi, Hans-Jörg Mischinger, Peter Kornprat
BACKGROUND: Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma with or without involvement of extranodal sites. Rituximab in combination with cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) therapy represents the current standard therapy, achieving a rather dissatisfying outcome in approximately 30-40% of all cases. CASE PRESENTATION: We present the case of a 43-year-old Austrian woman with an incidentally detected large pelvic mass which was diagnosed as diffuse large B-cell lymphoma...
October 13, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/30310366/comparison-of-the-clinicopathologic-characteristics-of-intraductal-papillary-neoplasm-of-the-bile-duct-according-to-morphological-and-anatomical-classifications
#4
Jae Ri Kim, Kyoung-Bun Lee, Wooil Kwon, Eunjung Kim, Sun-Whe Kim, Jin-Young Jang
Background: Intraductal papillary neoplasm of the bile duct (IPNB) is a recently defined entity and its clinical characteristics and classifications have yet to be established. We aimed to clarify the clinical features of IPNB and determine the optimal morphological classification criteria. Methods: From 2003 to 2016, 112 patients with IPNB who underwent surgery were included in the analysis. After pathologic reexamination by a specialized biliary-pancreas pathologist, previously suggested morphological and anatomical classifications were compared using the clinicopathologic characteristics of IPNB...
October 15, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/30310008/-lung-adenosquamous-cell-carcinoma-in-which-the-administration-of-nivolumab-became-untenable-due-to-bleeding-from-small-intestine-metastasis
#5
Nozomu Motono, Syun Iwai, Aika Funasaki, Atsushi Sekimura, Katsuo Usuda, Hidetaka Uramoto
A 59-year-old man who had postoperative recurrence of lung adenosquamous cell carcinoma was administered nivolumab as 3rd-line chemotherapy. Although nivolumab was considered effective, bleeding from a metastatic lesion at the jejunum was recognized by double-balloon enteroscopy, and partial resection was performed. Although the re-administration of nivolumab was planned, the patient died of acute respiratory failure 6 days postoperatively.
October 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/30309733/the-effect-of-intravenous-lipid-emulsions-and-mucosal-adaptation-following-massive-bowel-resection
#6
Shun Onishi, Tatsuru Kaji, Seiro Machigashira, Waka Yamada, Ryuta Masuya, Kazuhiko Nakame, Masato Kawano, Keisuke Yano, Koji Yamada, Takafumi Kawano, Motoi Mukai, Takako Yoshioka, Akihide Tanimoto, Satoshi Ieiri
AIMS AND OBJECTIVES: Fish oil (FO) lipid emulsion and a new lipid emulsion (SMOF) are important treatments for intestinal failure-associated liver disease. We evaluated the efficacy of FO and SMOF lipid emulsion on intestinal mucosal adaptation using a total parenteral nutrition (TPN)-supported rat model of short bowel syndrome. MATERIAL & METHODS: Sprague-Dawley rats underwent jugular vein catheterization and 90% small bowel resection and were divided into three groups: TPN with soy bean oil lipid emulsion (SO group), FO lipid emulsion (FO group), or SMOF (SMOF group)...
October 1, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/30303885/intra-abdominal-sepsis-after-ileocolic-resection-in-crohn-s-disease-the-role-of-combination-immunosuppression
#7
Nicholas P McKenna, Elizabeth B Habermann, Amy E Glasgow, Eric J Dozois, Amy L Lightner
BACKGROUND: Intra-abdominal sepsis complicates <10% of ileocolic resections for Crohn's disease, but the impact of combination immunosuppression and repeat resection on its development remains unknown. OBJECTIVE: The purpose of this study was to determine risk factors for intra-abdominal sepsis after ileocolic resection, specifically examining the role of combination immunosuppression and repeat intestinal resection. DESIGN: This was a retrospective review of patient records from 2007 to 2017...
October 9, 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/30302163/diagnosis-and-treatment-of-early-gastric-cancer-experience-of-one-center
#8
Zbigniew K Kula, Wojciech Zegarski, Wojciech Jóźwicki
Introduction: Gastric cancer is one of the most common malignant neoplasms in the world. Currently it constitutes the third cause of death among all malignancies. New endoscopic techniques have a potential to improve treatment results due to more frequent detection of early gastric cancer. Aim: To summarize our experience in diagnosis and treatment of early gastric cancer patients. Material and methods: We analyzed the results of endoscopic examination, histopathological findings and treatment methods in 16 patients who were diagnosed with early gastric cancer in the Endoscopy Unit of the Oncology Center in Bydgoszcz between 2014 and 2016...
2018: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/30301467/infant-progressive-colonic-stenosis-caused-by-antibiotic-related-clostridium-difficile-colitis-a-case-report-and-literature-review
#9
Xiaolong Xie, Bo Xiang, Yang Wu, Yiyang Zhao, Qi Wang, Xiaoping Jiang
BACKGROUND: Colonic stenosis is a rare cause of pediatric intestinal obstruction. The root cause underlying colonic stenosis is unclear and there is no fixed operation. CASE PRESENTATION: We reported on a male infant with progressive colonic stenosis caused by antibiotic-related colitis. The infant was admitted to our hospital with pneumonia but developed progressive abdominal distension and diarrhea following antibiotic treatment with meropenem. Initial testing of stool culture showed a Clostridium difficile infection...
October 9, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/30300980/buried-barrett-s-esophagus-with-high-grade-dysplasia-after-radiofrequency-ablation
#10
Joana Castela, Miguel Serrano, Susana Mão de Ferro, Daniela Vinha Pereira, Paula Chaves, António Dias Pereira
Radiofrequency ablation therapy is an effective endoscopic option for the eradication of Barrett's esophagus that appears to reduce the risk of esophageal cancer. A concern associated with this technique is the development of subsquamous/buried intestinal metaplasia, whose clinical relevance and malignant potential have not yet been fully elucidated. Fewer than 20 cases of subsquamous neoplasia after the successful radiofrequency ablation of Barrett's esophagus have been reported to date. Here, we describe a new case of subsquamous neoplasia (high-grade dysplasia) following radiofrequency ablation that was managed with endoscopic resection...
October 5, 2018: Clinical Endoscopy
https://www.readbyqxmd.com/read/30298207/choline-and-choline-related-nutrients-in-regular-and-preterm-infant-growth
#11
REVIEW
Wolfgang Bernhard, Christian F Poets, Axel R Franz
BACKGROUND: Choline is an essential nutrient, with increased requirements during development. It forms the headgroup of phosphatidylcholine and sphingomyelin in all membranes and many secretions. Phosphatidylcholine is linked to cell signaling as a phosphocholine donor to synthesize sphingomyelin from ceramide, a trigger of apoptosis, and is the major carrier of arachidonic and docosahexaenoic acid in plasma. Acetylcholine is important for neurodevelopment and the placental storage form for fetal choline supply...
October 8, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/30294683/surgical-treatment-of-jejunal-artery-aneurysm
#12
Teppei Toya, Kyokun Uehara, Yusuke Ito, Hiroaki Sasaki, Hitoshi Matsuda
Introduction: A jejunal artery aneurysm (JAA) is rare and has few specific symptoms. Endovascular repair is widely used in the treatment of jejunal artery aneurysms; however, some patients still require open repair. Report: A 59 year old man underwent open surgery with resection of the aneurysm and reconstruction using a saphenous vein graft. Histopathological examination revealed heterotopic pancreas around the aneurysm. Discussion: Inflammation as a result of heterotopic pancreas was suspected as the cause of JAA...
2018: EJVES Short Reports
https://www.readbyqxmd.com/read/30293133/gut-microbiota-imbalance-can-be-associated-with-non-malabsorptive-small-bowel-shortening-regardless-of-blind-loop
#13
Eduardo Lemos de Souza Bastos, Ana Maria Alvim Liberatore, Roberto Carlos Tedesco, Ivan Hong Jun Koh
INTRODUCTION: Some traditional bariatric surgery procedures may lead to functional gut shortening, which may unsettle the fine-tuned gastrointestinal physiology and affect gut microbiota balance. PURPOSE: Evaluate the gut microbiota behavior in rat models facing gut shortening due to intestinal bypass. MATERIALS AND METHODS: Wistar rats (n = 17) were randomly distributed in three groups: (1) sham group (n = 5); (2) blind loop group (n = 6); and (3) resection group (n = 6)...
October 6, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/30292093/cystic-mixed-adenoneuroendocrine-carcinoma-of-the-pancreas-a-case-report
#14
Nao Shimada, Shiro Miwa, Takuma Arai, Noriyuki Kitagawa, Shingo Akita, Nobuyoshi Iinuma, Keiko Ishii
INTRODUCTION: Pancreatic mixed adenoneuroendocrine carcinoma (MANEC) is a rare tumor. We report herein a case of pancreatic MANEC with cystic features. PRESENTATION OF CASE: A 67-year-old woman presented with jaundice. A CT scan revealed an 18-mm mass at the pancreatic head that obstructed the common bile duct and another 35-mm cystic lesion containing a mural nodule in the pancreatic body, which was suspected to be an intraductal papillary mucinous carcinoma. A biopsy of the head mass led to the diagnosis of adenocarcinoma...
September 23, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/30291440/linked-color-imaging-can-enhance-recognition-of-early-gastric-cancer-by-high-color-contrast-to-surrounding-gastric-intestinal-metaplasia
#15
Hisashi Fukuda, Yoshimasa Miura, Hiroyuki Osawa, Takahito Takezawa, Yuji Ino, Masahiro Okada, Tsevelnorov Khurelbaatar, Alan Kawarai Lefor, Hironori Yamamoto
BACKGROUND: Linked color imaging (LCI) increases the visibility of early gastric cancers, which may be associated with characteristic findings including background purple mucosae. These lesions are found in areas of chronic gastritis and surrounding mucosa. The aim of this study is to objectively characterize these lesions by color differences and color component values using LCI. METHODS: Fifty-two patients with early gastric cancer were enrolled. Color differences were calculated prospectively in malignant lesions and adjacent mucosa and compared with histological findings in resected specimens...
October 5, 2018: Journal of Gastroenterology
https://www.readbyqxmd.com/read/30284199/the-impact-of-a-multivisceral-resection-and-adjuvant-therapy-in-locally-advanced-colon-cancer
#16
Lieve G J Leijssen, Anne M Dinaux, R Amri, Hiroko Kunitake, Liliana G Bordeianou, David L Berger
BACKGROUND: Multivisceral resection for locally advanced colon cancer is mandatory to achieve complete tumor resection. We aimed to determine if local multivisceral resections (LMR) for pT4 and pT3 tumors impact perioperative and long-term oncological outcomes. METHODS: All stage II or III colon cancer patients who had surgery between 2004 and 2014 were identified. We analyzed patients with non-multivisceral resections (NMR) for pT4 tumors vs. pT4-LMR. In addition, outcomes were compared to both NMR and LMR pT3 patients...
October 3, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/30283802/unusual-complication-in-patient-with-gardner-s-syndrome-coexistence-of-triple-gastrointestinal-perforation-and-lower-gastrointestinal-bleeding-a-case-report-and-review-of-literature
#17
Sami Akbulut, Cemalettin Koc, Abuzer Dirican
Gardner's syndrome (GS) is a rare syndrome with autosomal dominant inheritance, which is characterized by multiple intestinal polyps, dental anomalies, desmoid tumors, and soft tissue tumors. All gastrointestinal symptoms seen in GS are associated with the underlying familial adenomatosis polyposis and abdominal desmoid tumors, with the most common symptoms being anemia, lower gastrointestinal bleeding, abdominal pain, diarrhea, obstruction, and mucous defecation. To our best knowledge, no case of GS that has presented with gastrointestinal perforation and bleeding has ever been reported in the English language medical literature...
September 26, 2018: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/30283599/endoscopic-therapy-for-barrett-s-esophagus-and-early-esophageal-cancer-where-do-we-go-from-here
#18
REVIEW
Tavankit Singh, Madhusudhan R Sanaka, Prashanthi N Thota
Since Barrett's esophagus is a precancerous condition, efforts have been made for its eradication by various ablative techniques. Initially, laser ablation was attempted in non-dysplastic Barrett's esophagus and subsequently, endoscopic ablation using photodynamic therapy was used in Barrett's patients with high-grade dysplasia who were poor surgical candidates. Since then, various ablative therapies have been developed with radiofrequency ablation having the best quality of evidence. Resection of dysplastic areas only without complete removal of entire Barrett's segment is associated with high risk of developing metachronous neoplasia...
September 16, 2018: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/30283288/jejunal-serrated-adenoma-diagnosed-and-treated-by-double-balloon-enteroscopy
#19
Anning Yin, Zhi Zeng, Xinyue Wan, Honggang Yu, Liang Zhao
Serrated polyps are most commonly located in the colorectum and have been well recognized as an important precursor lesion for colorectal cancer. Serrated adenoma in the small intestine has been reported more rarely but may represent a distinct morphological and biological subtype with malignant potential. Here, we present the case of a 65-year-old female who underwent double-balloon enteroscopy due to obscure gastrointestinal bleeding. A polyp sized 3.5 × 2.0 cm with a long pedicle in the jejunum, located 50 cm distal to the Treitz ligament, was detected...
May 2018: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/30282432/sinonasal-intestinal-type-adenocarcinoma-in-the-frontal-sinus
#20
Jaewoo Kim, Hak Chang, Euicheol C Jeong
Sinonasal intestinal-type adenocarcinoma is a rare neoplasm which can be diagnosed by pathologic report. Nasal obstruction, epistaxis, and rhinorrhea are common symptoms, but presenting with a benign-looking palpable mass is also possible. This is a report of our experience in diagnosing and treating a sinonasal intestinal-type low grade adenocarcinoma. A 63-year-old man initially presented with a rapidly growing palpable mass in the glabella region for 4 months. A malignancy of sinus origin was suspected on imaging studies...
September 2018: Archives of Craniofacial Surgery
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