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https://www.readbyqxmd.com/read/30517714/intestinal-plasticity-in-response-to-nutrition-and-gastrointestinal-surgery
#1
Maude Le Gall, Sophie Thenet, Doriane Aguanno, Anne-Charlotte Jarry, Laurent Genser, Lara Ribeiro-Parenti, Francisca Joly, Séverine Ledoux, André Bado, Johanne Le Beyec
The plasticity of a material corresponds to its capacity to change its feature under the effect of an external action. Intestinal plasticity could be defined as the ability of the intestine to modify its size or thickness and intestinal cells to modulate their absorption and secretion functions in response to external or internal cues/signals. This review will focus on intestinal adaptation mechanisms in response to diet and nutritional status. These physiological mechanisms allow a fine and rapid adaptation of the gut to promote absorption of ingested food, but they can also lead to obesity in response to overnutrition...
December 5, 2018: Nutrition Reviews
https://www.readbyqxmd.com/read/30514220/a-case-of-hepatic-anisakiasis-caused-by-pseudoterranova-decipiens-mimicking-metastatic-liver-cancer
#2
Yasuhiro Murata, Katsuhiko Ando, Masanobu Usui, Hiromu Sugiyama, Akinobu Hayashi, Akihiro Tanemura, Hiroyuki Kato, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno, Hiroyuki Sakurai, Shuji Isaji
BACKGROUND: Anisakid nematodes (Anisakis spp. or Pseudoterranova spp.) usually infect gastric or intestinal walls, while they rarely infect in extra-gastrointestinal sites of human body. Generally, Anisakis spp. larvae are highly infected in fish intermediate hosts, whereas Pseudoterranova spp. larvae are very rarely infected. To the best of our knowledge, there have been no reports which have documented cases of hepatic anisakiasis caused by Pseudoterranova spp. This report describes the first documented case of hepatic anisakiasis due to infection with Pseudoterranova decipiens and clinical features of the hepatic anisakiasis through literature review...
December 4, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/30511046/effects-of-cdx2-on-prognosis-and-chemotherapy-responsiveness-in-mismatch-repair-deficient-colorectal-cancer
#3
É J Ryan, B Creavin, Y L Khaw, M E Kelly, H M Mohan, R Geraghty, E J Ryan, R Kennelly, A Hanly, S T Martin, D Fennelly, R McDermott, D Gibbons, P R O'Connell, K Sheahan, D C Winter
Background: Caudal-related homeobox transcription factor 2 (CDX2) is an intestine-specific transcription factor implicated in tumour differentiation, proliferation, cell adhesion and migration. Negative CDX2 status (CDX2-) is associated with worse prognosis in colorectal cancer and may identify high-risk stage II disease that benefits from adjuvant chemotherapy. This observational study investigated whether CDX2- is associated with prognosis or response to chemotherapy in the mismatch repair-deficient (dMMR) phenotype of colorectal cancer...
December 2018: BJS open
https://www.readbyqxmd.com/read/30510833/case-report-seaweed-bezoar-masquerading-as-a-malignant-obstruction
#4
E C Abboud, B Babic
Bezoars represent a rare cause of small bowel obstruction (SBO). Nonoperative management of bezoars includes use of endoscopy with mechanical or chemical dissolution methods. When obstruction persists, surgical intervention becomes necessary. Here, we present the case of an Asian woman with a SBO secondary to a phytobezoar masquerading as a malignancy. She presented with two days of acute-on-chronic abdominal pain that started after eating seaweed. Initial computed tomography (CT) scan showed a SBO with a jejunal transition point and ill-defined liver lesions, worrisome for a malignant obstruction with liver metastases...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/30510634/coexistence-of-duodenum-derived-aggressive-fibromatosis-and-paraduodenal-hydatid-cyst-a-case-report-and-review-of-literature
#5
Sami Akbulut, Mehmet Yilmaz, Saadet Alan, Mehmet Kolu, Nese Karadag
Intra-abdominal aggressive fibromatosis is a locally aggressive tumor mostly originating from the mesentery or retroperitoneal space, infiltrating adjacent tissues, and very rarely metastasizing to distant organs. There are only two case reports in the English language literature where intra-abdominal aggressive fibromatosis originated from the intestinal wall. In this study, we aimed to report a case of aggressive fibromatosis originating from the muscularis propria layer of the duodenum and invading pancreas...
November 27, 2018: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/30510366/probe-based-confocal-endomicroscopy-is-accurate-for-differentiating-gastric-lesions-in-patients-in-a-western-center
#6
Adriana Vaz Safatle-Ribeiro, Elisa Ryoka Baba, Rodrigo Corsato Scomparin, Sheila Friedrich Faraj, Marcelo Simas de Lima, Luciano Lenz, Bruno Costa Martins, Carla Gusmon, Fábio Shiguehissa Kawaguti, Caterina Pennacchi, Bruno Zilberstein, Ulysses Ribeiro, Fauze Maluf-Filho
Objective: Probe-based confocal laser endomicroscopy (pCLE) technique may improve the diagnosis of gastric mucosal lesions allowing acquisition of high-resolution in vivo images at the cellular and microvascular levels. This study aims to evaluate the accuracy of pCLE for the differential diagnosis of non-neoplastic and neoplastic gastric lesions. Methods: Twenty gastric mucosal lesions from 10 patients were evaluated during endoscopic procedure and were examined by pCLE...
October 2018: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/30510364/immunohistochemical-expression-of-thymidylate-synthase-and-prognosis-in-gastric-cancer-patients-submitted-to-fluoropyrimidine-based-chemotherapy
#7
Marina Alessandra Pereira, Marcus Fernando Kodama Pertille Ramos, Andre Roncon Dias, Sheila Friedrich Faraj, Cinthya Dos Santos Cirqueira, Evandro Sobroza de Mello, Bruno Zilberstein, Venancio Avancini Ferreira Alves, Ulysses Ribeiro
Objective: Adjuvant chemotherapy with 5-fluorouracil (5-FU) has been widely used in gastric cancer (GC) patients to prevent relapse after curative resection. 5-FU acts by inhibiting thymidylate synthase (TS), and high levels of TS correlate with resistance to treatment with fluoropyrimidines. The aim of this study was to evaluate the expression of TS in GC patients, and its relation with clinicopathological characteristics and prognosis in adjuvant chemotherapy with 5-FU. Methods: We retrospectively evaluated 285 patients who underwent D2-gastrectomy with curative intent...
October 2018: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/30508962/primary-small-bowel-mesentery-de-differentiated-liposarcoma-causing-torsion-with-no-recurrence-for-5-years-a-case-report-and-review-of-the-literature
#8
Kentaro Matsuo, Masaya Inoue, Yasutsugu Shirai, Tatsuki Kataoka, Shuji Kagota, Kohei Taniguchi, Sang-Woong Lee, Kazuhisa Uchiyama
RATIONALE: Liposarcoma (LPS) is a rare malignant soft-tissue tumor. Management of LPS is relatively difficult, because there are no characteristic symptoms, or biomarkers, nor any established effective treatment. Hence, the report of the accumulation of each LPS case is necessary. We experienced an extremely rare case of torsion caused by a primary small bowel mesentery LPS. PATIENT'S CONCERN: A 70-year-old male consulted our hospital with the complaints of abdominal pain and sudden vomiting...
November 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30508940/protein-losing-enteropathy-secondary-to-nonocclusive-mesenteric-ischemia-a-case-report
#9
Takafumi Shima, Maiko Ozeki, Takashi Kinoshita, Kotaro Honda, Hitoshi Inoue, Shinsho Morita
RATIONALE: Nonocclusive mesenteric ischemia (NOMI) is a life-threatening disorder; prompt diagnosis is vital. Surgical treatment is often required, but some cases can be treated conservatively. We herein report an extremely rare case wherein protein-losing enteropathy (PLE) developed after conservative treatment of NOMI. PATIENT CONCERNS: The patient was a 66-year-old man. He underwent laparoscopic super low anterior resection and temporary ileostomy for sigmoid colon cancer and rectum cancer...
November 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30506539/-analysis-of-clinical-features-and-prognostic-factors-on-reoperation-patients-with-postoperative-recurrence-or-metastasis-of-gastrointestinal-stromal-tumor
#10
Lingquan Wang, Wei Xu, Xuexin Yao, Chao Yan, Chen Li, Zhenggang Zhu, Wentao Liu, Min Yan
OBJECTIVE: To investigate the clinical characteristics and prognostic factors of reoperation patients with postoperative recurrence or metastasis of gastrointestinal stromal tumor (GIST). METHODS: A retrospective case-control study was performed on the clinical data of 31 patients with GIST who had recurrence or metastasis after the first surgery and underwent one or more operations again from February 2003 to January 2016 at Ruijin Hospital, Shanghai Jiaotong University School of Medicine...
November 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/30506536/-effect-of-bladder-training-on-bladder-function-recovery-in-the-male-patients-after-mid-low-rectal-cancer-surgery-a-prospective-open-randomized-controlled-study
#11
Yuhong Xie, Xiaojie Wang, Zhifen Chen, Pan Chi, Guoxian Guan, Huiming Lin, Xingrong Lu, Ying Huang, Zhengqiong Wang, Mingxing Wang, Jie Chen, Xiuying Li, Min Wang, Xuezhen Zheng, Ximei Zheng, Ran Li, Qianqian Lin
OBJECTIVE: To investigate the efficacy and safety of the bladder training in male patients before urinary catheter removal after mid-low rectal cancer surgery. METHODS: This was a prospective, open, randomized controlled study. INCLUSION CRITERIA: male patients; pathologically diagnosed as mid-low rectal adenocarcinoma; distance from tumor lower edge to anal margin ≤10 cm; standard radical surgery for rectal cancer, including intestinal resection and regional lymph node dissection...
November 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/30506535/-application-of-overlapped-delta-shaped-anastomosis-technique-in-totally-laparoscopic-right-hemicolectomy
#12
Xuewei Wang, Peng Wang, Jun Hong, Hao Su, Jianwei Liang, Xishan Wang, Qian Liu, Haitao Zhou, Zhixiang Zhou
OBJECTIVE: To explore the safety and feasibility of the overlapped delta-shaped anastomosis (ODA) technique for cases undergoing totally laparoscopic right hemicolectomy (TLRH). METHODS: Clinical data of patients who underwent TLRH using the ODA technique or the modified delta-shaped anastomosis (MDA) technique at Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College from January 2016 to December 2017 were retrospectively analyzed...
November 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/30499415/long-term-outcome-of-infants-with-nec
#13
S Federici, L De Biagi
Necrotizing enterocolitis (NEC) is a significant complication for premature newborns. Infants who survive NEC are at increased risk of having poor long-term physiological and neurodevelopmental growth. The objective of this paper is to give a comprehensive description of the long-term consequences of NEC. Despite the rise in incidence of NEC there is a paucity of data regarding long-term outcomes of these infants that can be divided into two groups. The first group includes gastrointestinal complications that could occur in relation to the bowel disease, the surgical treatment and quality of the residual bowel...
November 30, 2018: Current Pediatric Reviews
https://www.readbyqxmd.com/read/30498853/enterocutaneous-fistula-in-severely-active-crohn-s-disease-preoperative-anti-tnf-alpha-treatment-to-limit-bowel-resection-report-of-a-case
#14
Peter Wilhelm, Andreas Kirschniak, Jonas Johannink, Sascha Kaufmann, Thomas Klag, Jan Wehkamp, Claudius Falch
PURPOSE: Strategies for limiting the extent of bowel resection in cases of enterocutaneous or interenteric fistulas in severely active Crohn's disease are urgently necessary. Anti-inflammatory therapy with tumor necrosis factor alpha (anti-TNF alpha) inhibitors has positive impact on fistulizing Crohn's disease. We describe a case of a 32-year-old male suffering from enterocutaneous fistula in severely active Crohn's disease. METHODS: The patient's clinical course and data of therapy monitoring before bowel resection were reviewed and compared to the pretherapeutic findings...
November 29, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/30483587/risk-factors-for-postoperative-infection-after-gastrointestinal-surgery-among-adult-patients-with-inflammatory-bowel-disease-findings-from-a-large-observational-us-cohort-study
#15
Huifang Liang, Baoguo Jiang, Sudhakar Manne, Trevor Lissoos, Dimitri Bennett, Paul Dolin
Background and Aim: Postoperative infection (POI) is a major source of morbidity and prolongation of hospitalization in inflammatory bowel disease (IBD) patients. This large observational study was conducted to further describe risk factors and to quantify the proportion of POIs that are preventable. Methods: We conducted a retrospective cohort analysis of the Optum US health insurance claims database. The study population included adults with ulcerative colitis (UC) or Crohn's disease (CD) who underwent lower gastrointestinal (GI) surgery of small intestine, colon, rectum, or anus during September 2014 to September 2016...
October 2018: JGH open: an open access journal of gastroenterology and hepatology
https://www.readbyqxmd.com/read/30483583/histoplasmosis-induced-ileal-perforation-in-a-patient-with-acquired-immune-deficiency-syndrome-case-report
#16
Alvaro Bellido-Caparó, Sandra Delgado Málaga, Carlos Garcia Encinas, Jorge Luis Espinoza-Rios, Jaime Cáceres Pizarro, Martin Tagle Arróspide
Intestinal involvement with disseminated histoplasmosis is common in some populations infected with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS), especially in those who come from tropical zones. We report the case of a 29-year-old male patient, from a tropical zone, with HIV infection and a CD4 value less than 50 cells/mm3 , with a history of abdominal pain, fever, diarrhea, and weight loss. On presentation, he was pale, sweaty, and had abdominal rebound tenderness. Laboratory findings demonstrated microcitic hipocromic anemia, azoemia, and hypoalbuminemia...
August 2018: JGH open: an open access journal of gastroenterology and hepatology
https://www.readbyqxmd.com/read/30482824/high-grade-gastrointestinal-neuroendocrine-carcinoma-management-and-outcomes-a-national-cancer-database-study
#17
Olatunji B Alese, Renjian Jiang, Walid Shaib, Christina Wu, Mehmet Akce, Madhusmita Behera, Bassel F El-Rayes
BACKGROUND: High-grade neuroendocrine carcinomas are rare in the gastrointestinal tract. However, treatment patterns and outcomes have not been well described. SUBJECTS, MATERIALS, AND METHODS: The National Cancer Database was analyzed. The primary objective was to describe the clinical outcomes and identify prognostic factors. Univariate and multivariate analyses were done to identify factors associated with patient outcome. RESULTS: A total of 1,861 patients were identified between 2004 and 2013...
November 27, 2018: Oncologist
https://www.readbyqxmd.com/read/30482184/spigelian-hernia-in-the-right-upper-abdominal-wall-a-case-report
#18
Zhou Ye, Mo-Jin Wang, Li-Fen Bai, Han-Xiang Zhuang, Wen Zhuang
BACKGROUND: Spigelian hernia (SH) is rare and constitutes less than 2% of all hernias. It is reported that more than 90% of SHs lie in the "Spigelian belt", but SH in the upper abdominal wall is extremely uncommon. Here, we report a case of SH in the right upper quadrant of abdomen. CASE PRESENTATION: A 38-year-old female was admitted to hospital with complaints of abdominal pain and right upper quadrant mass for 10 days. Contrast-enhanced computed tomography (CECT) of abdomen revealed the dilated small intestine between the swelling ventral muscles in the right upper abdominal wall which suggested a ventral hernia...
November 27, 2018: BMC Surgery
https://www.readbyqxmd.com/read/30475602/a-novel-near-infrared-fluorescent-probe-tmtp1-peg4-icg-for-in-vivo-tumor-imaging
#19
Ying Zhou, Jiang Guiying, Wei Wang, Rui Wei, Xi Chen, Xueqian Wang, Juncheng Wei, Ding Ma, Fei Li, Ling Xi
Molecular imaging agents are considered to be promising tracers for tumor imaging and guided therapy. TMTP1 was screened through the FliTrx bacterial peptide display system in our laboratory previously and shown to specifically target to primary tumors and metastatic foci. In this study, Small peptide TMTP1 was designed to conjugate to a near-infrared fluorescent agent ICG derivative ICG-OSu through PEG4, forming the novel probe TMTP1-PEG4-ICG. It was successfully synthesized and certificated. CCK-8 assay showed it was nontoxic to normal cells and cancerous cells...
November 26, 2018: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/30474492/rate-of-anastomotic-leakage-after-rectal-anastomosis-depends-on-the-definition-pelvic-abscesses-are-significant
#20
B C Olsen, S T Sakkestad, F Pfeffer, A Karliczek
BACKGROUND AND AIMS: The International Study Group of Rectal Cancer has proposed that a pelvic abscess in the proximity of the anastomosis is considered an anastomotic leak, whether or not its point of origin is detectable. This study describes how the inclusion of pelvic abscesses alters the leakage rate. MATERIAL AND METHODS: Risk factors and postoperative complications in patients with visible anastomotic leakage ("direct leakage"), pelvic abscesses alone in the vicinity of a visibly intact anastomosis ("abscess leakage"), and no leakage were retrospectively evaluated...
November 25, 2018: Scandinavian Journal of Surgery: SJS
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