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https://www.readbyqxmd.com/read/30531678/a-rare-case-of-thyrotoxic-periodic-paralysis-after-epidural-steroid-injection-a-case-report-and-literature-review
#1
Kwame Ofori Affram, Tanya Luke Reddy, Kofi M Osei
BACKGROUND Thyrotoxic periodic paralysis (TPP) is a rare cause of acute paralysis, which if not promptly recognized and treated, can lead to significant morbidity and mortality. TPP can be precipitated by several factors, including a high carbohydrate diet and exercise. This report is of a rare case of TPP after epidural steroid injection in a young man, with a review of the literature of previous cases. CASE REPORT A 36-year-old Asian man presented to the emergency department with sudden onset of paralysis of all his limbs following epidural steroid injection for traumatic low back pain...
December 8, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/30526785/-percutaneous-endoscopic-transforaminal-lumbar-interbody-fusion-for-lumbar-spinal-stenosis
#2
J C Yang, Y Hai, Y Ding, P Yin, Y S Zhang, C Liu, L M Zhang
Objective: To evaluate the clinical effects of percutaneous endoscopic transforaminal lumbar interbody fusion (PE-TLIF) for L(4/5) single-segment lumbar spinal stenosis. Methods: From September 2016 to March 2018, 7 patients with L(4/5) single-segment lumbar spinal stenosis were treated by PE-TLIF in the Department of Orthopedics, Beijing Chaoyang Hospital. There were 1 male and 6 females, with a mean age of (57±13) years(43-77 years). The operation time, intraoperative blood lose, blood transfusion and complications were recorded, and the pain relief effects were evaluated by visual analog scale (VAS) score and Oswestry dability index (ODI)...
December 4, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30525407/ultralight-superelastic-and-fatigue-resistant-graphene-aerogel-templated-by-graphene-oxide-liquid-crystal-stabilized-air-bubbles
#3
Xiaofang Zhang, Tongping Zhang, Zhi Wang, Zhongjie Ren, Shouke Yan, Yongxin Duan, Jianming Zhang
Graphene aerogel (GA) has attracted great attention due to its unique properties, such as ultralow density, superelasticity and multifunctionality. However, it is a great challenge to develop superelastic and fatigue resistant GA (SFGA) with ultralow density because it is generally contradictory to improve the mechanical properties with reducing density of GA. Herein, we report a simple and efficient approach to preparing ultralight SFGA templated by graphene oxide liquid crystal (GOLC) stabilized air bubbles...
December 10, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/30524381/a-new-role-of-ompr-in-acid-and-osmotic-stress-in-salmonella-and-e-coli
#4
Smarajit Chakraborty, Linda J Kenney
Bacteria survive and respond to diverse environmental conditions and during infection inside the host by systematic regulation of stress response genes. E. coli and S . Typhimurium can undergo large changes in intracellular osmolality (up to 1.8 Osmol/kg) and can tolerate cytoplasmic acidification to at least pHi 5.6. Recent analyses of single cells challenged a long held view that bacteria respond to extracellular acid stress by rapid acidification followed by a rapid recovery. It is now appreciated that both S ...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/30511904/the-reparative-effects-of-human-adipose-derived-mesenchymal-stem-cells-in-the-chemotherapy-damaged-thymus
#5
Ying Zhan, Lihua Wang, Guangyang Liu, Xiaohui Zhang, Jingci Yang, Yuxia Pan, Jianmin Luo
Hematological patients who accept chemotherapy always develop secondary tumor or even die of severe infections. As an important central lymphoid organ, the thymus is frequently damaged during chemotherapy. Previous studies showed that the mesenchymal stem cells (MSCs) can promote the proliferation and repair of epithelial cells in thymus. The purpose of our study is to investigate the reparative effects of human adipose-derived mesenchymal stem cells (hADMSCs) for chemotherapy treated damaged thymus. 80 mice were randomly divided into four groups: normal group, model control group, hADMSCs untreated group and hADMSCs treated group...
December 4, 2018: Stem Cells and Development
https://www.readbyqxmd.com/read/30504705/hemodialysis-or-peritoneal-dialysis-which-is-better-for-patients-with-delayed-graft-function
#6
Ting Yan, Wenhan Peng, Junhao Lv, Jianyong Wu, Jianghua Chen
BACKGROUND/AIMS: Hemodialysis (HD) or peritoneal dialysis (PD) is an important renal replacement method in patients with delayed graft function (DGF) after kidney transplantation; however, it is not clear which dialysis modality is superior. This study determined the impact of different dialysis modalities on patients with DGF. METHODS: It was a single-center, retrospective and descriptive study. We performed 673 kidney transplants from donors after cardiac death (DCD) between January 2010 and December 2016 at our center and 138 (20...
November 30, 2018: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/30503306/decreasing-length-of-hospital-stay-and-postoperative-complications-after-primary-total-hip-arthroplasty-a-decade-analysis-from-2006-to-2016
#7
Matthew J Grosso, Alexander L Neuwirth, Venkat Boddapati, Roshan P Shah, H John Cooper, Jeffrey A Geller
BACKGROUND: In an attempt to decrease costs without increasing complication burden, the development of rapid recovery protocols has led to an increased push for decreased length of hospital stay (LOS) following total hip arthroplasty (THA). The purpose of this study was to analyze trends in LOS and complications following THA over a 10-year period. METHODS: Using the National Surgical Quality Improvement Program registry from 2006 to 2016, we identified all patients who underwent primary THA...
November 12, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/30499483/-the-application-of-combined-low-intensity-laser-therapy-for-the-treatment-of-the-patients-presenting-with-trophic-ulcers-associated-with-chronic-venous-insufficiency-of-the-lower-extremities
#8
E V Askhadulin, T V Konchugova, S V Moskvin
AIM: The objective of the present study was the evaluation of the effectiveness of the combined treatment of the patients presenting with trophic ulcers associated with chronic venous insufficiency of the lower extremities of venous etiology with the application of low-intensity laser therapy (LILT) at different wavelengths. MATERIAL AND METHODS: The study included the patients presenting with chronic venous insufficiency (CVI) (class C6 in accordance with the CEAP clinical classification)...
2018: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/30497334/a-preliminary-clinical-experience-using-hypothermic-oxygenated-machine-perfusion-for-rapid-recovery-of-octogenarian-liver-grafts
#9
Michel Rayar, Betty Maillot, Damien Bergeat, Christophe Camus, Pauline Houssel-Debry, Laurent Sulpice, Bernard Meunier, Karim Boudjema
No abstract text is available yet for this article.
November 29, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/30496903/endovascular-and-surgical-management-in-intact-splenic-artery-aneurysm
#10
Chenmou Zhu, Jichun Zhao, Ding Yuan, Bin Huang, Yi Yang, Yukui Ma, Fei Xiong
OBJECTIVE: This study aims to reveal the experience with endovascular and surgical management of intact splenic artery aneurysms in our single center. METHOD: Between January 2011 and June 2017, 42 patients with intact splenic artery aneurysm were enrolled in this study. Twenty patients undergoing surgical intervention were classified as the surgical group, and twenty-two patients who received endovascular repair were categorized as the endovascular group. Demographic data, preoperative comorbidities, and aneurysm anatomical characteristics were collected and analyzed...
November 26, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/30486621/retroperitoneal-extrapleural-approach-for-corpectomy-of-the-first-lumbar-vertebra-technique-and-outcome
#11
Ihab Zidan, Wael Khedr, Ahmed Abdelaziz Fayed, Ahmed Farhoud
Objective: Corpectomy of the first lumbar vertebra (L1) for the management of different L1 pathologies can be performed using either an anterior or posterior approach. The aim of this study was to evaluate the usefulness of a retroperitoneal extrapleural approach through the twelfth rib for performing L1 corpectomy. Methods: Thirty consecutive patients underwent L1 corpectomy between 2010 and 2016. The retroperitoneal extrapleural approach through the 12th rib was used in all cases to perform single-stage anterior L1 corpectomy, reconstruction and anterior instrumentation, except for in two recurrent cases in which posterior fixation was added...
November 30, 2018: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/30474446/biotechnological-management-of-angiopathic-wounds-challenges-and-perspectives
#12
Yufeng Jiang, Meirong Li, Xiaobing Fu
Angiopathic wound is a wound that develops as a result of a local vascular lesion. Angiogenesis is an important aspect underlying repair, and increased angiogenesis could accelerate and improve the healing outcome. Biotherapy has been used more and more in clinic and brings hope for angiopathic wound treatment, through the rapid recovery of angiogenesis and regulation and correction of the whole wound microenvironment. In this article, we discuss the advantages and disadvantages of various technologies ranging from presentation of angiogenic growth factors, genetic strategies, stem cells, and biomaterials engineering in angiopathic wound treatment...
November 25, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/30463162/seasonal-time-series-reveal-the-impact-and-rapid-recovery-in-richness-abundance-and-community-structure-of-benthic-macroinvertebrates-following-catchment-wildfire
#13
Kieran A Monaghan, Ana L Machado, Margarida Corado, Frederick J Wrona, Amadeu M V M Soares
Catchment wildfire can decimate freshwater benthos when burnt material washes through river channels. We conducted detailed seasonal surveys over the course of one-year at N = 9 sites following summer-time wildfire in 2009 and N = 3 sites following summer-time wildfire in 2010 (constituting one-year time-series of 9 ∗ 5 and 3 ∗ 5 samples, respectively). Basic one-year-on surveys were conducted at an additional 12 sites following 2009 wildfires (Sumpostfire :Sum+one.yr ; N = 12 ∗ 2)...
February 15, 2019: Science of the Total Environment
https://www.readbyqxmd.com/read/30451775/bone-marrow-aspirate-concentrate-for-orthopaedic-use
#14
Jorge Chahla, Jeremy A Alland, Nikhil N Verma
Biological-based therapies are rapidly expanding for different musculoskeletal conditions because of their potential benefits including their minimal invasiveness, capacity for unprecedented healing, and potential for rapid recovery. In this regard, although several approaches have been reported in the literature, most of the body of the literature is increasingly based on platelet-rich plasma, bone marrow aspirate concentrate, and cell-based therapy studies. Although further basic science and clinical research is needed to elucidate the long-term outcome of these therapies in the treatment of several injuries, there is compelling evidence for their use for certain indications...
November 2018: Orthopaedic Nursing
https://www.readbyqxmd.com/read/30445967/severe-plasmodium-vivax-malaria-hiv-tuberculosis-co-infection-in-a-sri-lankan-traveller-case-management-and-challenges-during-the-prevention-of-malaria-reintroduction-phase
#15
Dewanee Ranaweera, R M J Kanchana Rajapaksha, Priyanganie Silva, Raja Hettiarachchi, W M Kumudu T de A W Gunasekera, Hemantha Herath, Deepika Fernando
BACKGROUND: The country received malaria-free certification from WHO in September 2016, becoming only the second country in the WHO South East Asia region to be declared malaria-free. Imported malaria cases continue to be reported, with 278 cases reported between 2013 and 2017. The diagnosis of a severe Plasmodium vivax patient co-infected with HIV and tuberculosis is discussed with an overview of the rapid response mounted by the Anti Malaria Campaign (AMC), Sri Lanka. CASE PRESENTATION: A Sri Lankan gem miner who returned from Madagascar on the 6th of April 2018 presented to a private hospital for a malaria diagnostic test on the 21st April, 2 days after the onset of fever...
November 16, 2018: Malaria Journal
https://www.readbyqxmd.com/read/30440104/management-of-sacrococcygeal-pilonidal-sinus-disease
#16
Rhiannon L Harries, Abdullah Al-Qallaf, Jared Torkington, Keith G Harding
The ideal treatment for patients who suffer from pilonidal sinus disease should lead to a cure with a rapid recovery period allowing a return to normal daily activities, with a low level of associated morbidity. A variety of different surgical techniques have been described for the primary treatment of pilonidal sinus disease and current practice remains variable and contentious. Whilst some management options have improved outcomes for some patients, the complications of surgery, particularly related to wound healing, often remain worse than the primary disease...
November 15, 2018: International Wound Journal
https://www.readbyqxmd.com/read/30431127/conditioned-medium-from-human-palatine-tonsil-mesenchymal-stem-cells-attenuates-acute-graft%C3%A2-vs-%C3%A2-host-disease-in-mice
#17
Kyung-Ah Cho, Yu-Hee Kim, Minhwa Park, Hye Ji Kim, So-Youn Woo, Joo-Won Park, Kyung-Ha Ryu
Graft-vs.-host disease (GVHD) is a severe and potentially life-threatening complication of hematopoietic stem cell transplantation. Approximately 50% of patients exhibiting GVHD will not benefit from conventional steroid treatment. Although several second‑line treatments are available for these patients, their prognoses remain poor due to the increased risk of infection, immunosuppression-mediated toxicity and incomplete GVHD remission, which occurs in the majority of cases. Mesenchymal stem cells (MSCs), a multipotent cell population, possess broad immunosuppressive activity and are a reportedly effective treatment of GVHD...
November 13, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/30411088/activity-and-circadian-rhythm-of-sepsis-patients-in-the-intensive-care-unit
#18
Anis Davoudi, Duane B Corbett, Tezcan Ozrazgat-Baslanti, Azra Bihorac, Scott C Brakenridge, Todd M Manini, Parisa Rashidi
Early mobilization of critically ill patients in the Intensive Care Unit (ICU) can prevent adverse outcomes such as delirium and post-discharge physical impairment. To date, no studies have characterized activity of sepsis patients in the ICU using granular actigraphy data. This study characterizes the activity of sepsis patients in the ICU to aid in future mobility interventions. We have compared the actigraphy features of 24 patients in four groups: Chronic Critical Illness (CCI) sepsis patients in the ICU, Rapid Recovery (RR) sepsis patients in the ICU, non-sepsis ICU patients (control-ICU), and healthy subjects...
March 2018: IEEE-EMBS International Conference on Biomedical and Health Informatics
https://www.readbyqxmd.com/read/30399420/phase-i-ii-trial-of-a-combination-of-anti-cd3-cd7-immunotoxins-for-steroid-refractory-acute-graft-versus-host-disease
#19
Christoph Groth, Lenneke F J van Groningen, Tiago R Matos, Manita E Bremmers, Frank W M B Preijers, Harry Dolstra, Christian Reicherts, Nicolaas P M Schaap, Eric H G van Hooren, Joanna IntHout, Rosalinde Masereeuw, Mihai G Netea, John E Levine, George Morales, James L Ferrara, Nicole M A Blijlevens, Ypke V J M van Oosterhout, Matthias Stelljes, Walter J F M van der Velden
Effective therapies for treating patients with steroid-refractory acute graft-versus-host-disease (SR-aGVHD), particularly strategies that reduce the duration of immunosuppression following remission, are urgently needed. The investigated immunotoxin combination consists of a mixture of anti-CD3 and anti-CD7 antibodies separately conjugated to recombinant ricin A (CD3/CD7-IT), which induces in vivo depletion of T cells and natural killer (NK) cells and suppresses T cell receptor activation. We conducted a phase I/II trial to examine the safety and efficacy of CD3/CD7-IT in 20 patients with SR-aGVHD; 17 of these patients (85%) had severe SR-aGVHD, and all 20 patients had visceral organ involvement, including 18 (90%) with gastrointestinal (GI) involvement and 5 (25%) with liver involvement...
November 3, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/30389073/pediatric-electroconvulsive-therapy-an-anesthesiologist-s-perspective
#20
REVIEW
Andrew D Franklin, Jenna H Sobey, Eric T Stickles
Proper planning and communication between psychiatry and anesthesiology teams is vital to conferring the greatest therapeutic benefit to children presenting for electroconvulsive therapy while minimizing risk. Anesthesia for the child undergoing electroconvulsive therapy should ideally provide deep hypnosis, ensure muscle relaxation to reduce injury, have minimal effect on seizure dynamics, and allow for rapid recovery to baseline neurologic and cardiopulmonary status. Unique factors for pediatric electroconvulsive therapy include the potential need for preoperative anxiolytic and inhalational induction of anesthesia, which must be weighed against the detrimental effects of anesthetic agents on the evoked seizure quality required for a successful treatment...
January 2019: Child and Adolescent Psychiatric Clinics of North America
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