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https://www.readbyqxmd.com/read/30328957/noninvasive-brain-stimulation-in-psychiatric-disorders-a-primer
#1
Andre R Brunoni, Bernardo Sampaio-Junior, Adriano H Moffa, Luana V Aparício, Pedro Gordon, Izio Klein, Rosa M Rios, Lais B Razza, Colleen Loo, Frank Padberg, Leandro Valiengo
OBJECTIVE: Noninvasive brain stimulation (NIBS) techniques, such as transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS), are increasingly being used to treat mental disorders, particularly major depression. The aim of this comprehensive review is to summarize the main advances, limitations, and perspectives of the field. METHODS: We searched PubMed and other databases from inception to July 2017 for articles, particularly systematic reviews and meta-analyses, evaluating the use of NIBS in psychiatric disorders...
October 11, 2018: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/30312634/the-dynamic-duo-combining-noninvasive-brain-stimulation-with-cognitive-interventions
#2
REVIEW
Aakash V Sathappan, Bruce M Luber, Sarah H Lisanby
Pharmacotherapy, psychotherapy, and non-invasive brain stimulation (NIBS)1 each show efficacy in the treatment of psychiatric disorders; however, more efficacious interventions are needed as reflected by an overall unmet need in mental health care. While each modality has typically been studied and developed as a monotherapy, in practice they are typically used in combination. Research has begun to emerge studying the potential synergistic actions of multi-modal, combination therapies. For example, NIBS combined with rehabilitation strategies have demonstrated some success for speech and motor rehabilitation in stroke patients...
October 9, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/30295660/the-combined-use-of-transcranial-direct-current-stimulation-and-robotic-therapy-for-the-upper-limb
#3
Marcus Yu Bin Pai, Thais Tavares Terranova, Marcel Simis, Felipe Fregni, Linamara Rizzo Battistella
Neurologic disorders such as stroke and cerebral palsy are leading causes of long-term disability and can lead to severe incapacity and restriction of daily activities due to lower and upper limb impairments. Intensive physical and occupational therapy are still considered main treatments, but new adjunct therapies to standard rehabilitation that may optimize functional outcomes are being studied. Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that polarizes underlying brain regions through the application of weak direct currents through electrodes on the scalp, modulating cortical excitability...
September 23, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/30264605/gambling-disorder-and-bilateral-transcranial-direct-current-stimulation-a-case-report
#4
Giovanni Martinotti, Eleonora Chillemi, Matteo Lupi, Luisa De Risio, Mauro Pettorruso, Massimo Di Giannantonio
INTRODUCTION: Gambling disorder (GD) is a major public health concern with currently no validated and efficacious treatments approved. In this single case study, we report the short- and long-term effect of bilateral transcranial direct current stimulation (tDCS) of dorsolateral prefrontal cortex (DLPFC) on craving and impulse control in a subject with GD. METHODS: The patient is a 26-year-old Caucasian male with an 8-year history of GD as well as alcohol and cocaine misuse...
September 1, 2018: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/30244001/deontological-morality-can-be-experimentally-enhanced-by-increasing-disgust-a-transcranial-direct-current-stimulation-study
#5
Cristina Ottaviani, Francesco Mancini, Samantha Provenzano, Alberto Collazzoni, Francesca D'Olimpio
Previous studies empirically support the existence of a distinctive association between deontological (but not altruistic) guilt and both disgust and obsessive-compulsive (OC) symptoms. Given that the neural substrate underlying deontological guilt comprises brain regions strictly implicated in the emotion of disgust (i.e. the insula), the present study aimed to test the hypothesis that indirect stimulation of the insula via transcranial direct current stimulation (tDCS) would enhance disgust and morality in the deontological domain...
October 2018: Neuropsychologia
https://www.readbyqxmd.com/read/30235920/hypomania-induced-by-bifrontal-transcranial-direct-current-stimulation-in-a-patient-with-bipolar-depression
#6
Pei-Chun Chao, Chuan-Chia Chang, Hsin-An Chang
Transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique, has been increasingly used to treat bipolar depression. Researchers recently noticed the risk of tDCS-emergent mania/hypomania in depressed patients and started to evaluate this risk by launching a meta-analysis. Here we present a female with bipolar II depression who rapidly developed hypomanic switching during bifrontal tDCS.
September 2018: Psychiatry Investigation
https://www.readbyqxmd.com/read/30218585/nicotine-modulates-human-brain-plasticity-via-calcium-dependent-mechanisms
#7
Jessica Grundey, Jerick Barlay, Giorgi Batsikadze, Min-Fang Kuo, Walter Paulus, Michael Nitsche
KEY POINTS: Nicotine (NIC) modulates cognition and memory function by targeting the nicotinic ACh receptor and releasing different transmitter systems postsynaptically. With both NIC-generated mechanisms, calcium influx and calcium permeability can be regulated, which is a key requirement for the induction of long-term potentiation, comprising the physiological basis of learning and memory function. We attempt to unmask the underlying mechanism of nicotinic effects on anodal transcranial direct current stimulation (tDCS)-induced long-term potentiation-like plasticity based on the hypothesis of calcium-dependency...
September 15, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/30153360/feasibility-of-computerized-cognitive-behavioral-therapy-combined-with-bifrontal-transcranial-direct-current-stimulation-for-treatment-of-major-depression
#8
Emma S Welch, Anne Weigand, Julia E Hooker, Noah S Philip, Audrey R Tyrka, Daniel Z Press, Linda L Carpenter
BACKGROUND: Cognitive behavioral therapy (CBT) is effective in the treatment of major depressive disorder (MDD). Transcranial Direct Current Stimulation (tDCS) has demonstrated preliminary antidepressant effects and beneficial effects on cognitive function. OBJECTIVE: We investigated the feasibility and acceptability of using tDCS to enhance the effects of computer-based CBT for treatment of MDD. MATERIALS AND METHODS: In a randomized, double-blind, sham-controlled study, 14 patients with MDD on stable or no pharmacotherapy received active or sham bifrontal tDCS for four weeks with concurrent CBT...
August 28, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30147655/optimizing-electrode-montages-of-transcranial-direct-current-stimulation-for-attentional-bias-modification-in-early-abstinent-methamphetamine-users
#9
Alireza Shahbabaie, Javad Hatami, Ali Farhoudian, Hamed Ekhtiari, Ali Khatibi, Michael A Nitsche
Introduction: Chronic use of most psychoactive drugs may lead to substance dependence and drug addiction. Drug addiction is a chronically relapsing disorder, and current pharmacological and behavioral therapies are not fully efficient. Attentional bias (AB) is hypothesized to have a causal contribution to substance abuse, addiction development and, maintenance. Transcranial direct current stimulation (tDCS) has been of increasing interest in the past few years as a means for modulating neuroplasticity of the human brain...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/30145715/increased-interhemispheric-synchrony-underlying-the-improved-athletic-performance-of-rowing-athletes-by-transcranial-direct-current-stimulation
#10
Xiaoyun Liu, Xi Yang, Zhenghua Hou, Ming Ma, Wenhao Jiang, Caiyun Wang, Yuqun Zhang, Yonggui Yuan
To explore the mechanism of transcranial direct current stimulation (tDCS) on the improved performance of professional rowing athletes. Twelve male professional rowing athletes were randomly divided into two groups (low-stimulation group, 1 mA, n = 6; high-stimulation group, 2 mA, n = 6), and they accepted tDCS for two consecutive weeks while undergoing regular training (20 min each time, five times a week, totally ten times). The assessments of depression, anxiety, executive function, fatigue perception, lactate threshold power (LTP) and isokinetic muscle strength as well as the collection of functional magnetic resonance imaging (fMRI) data were performed at baseline and at follow-up (the end of the fourth week)...
August 25, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/30132389/transcranial-direct-current-stimulation-may-improve-cognitive-motor-function-in-functionally-limited-older-adults
#11
Brad Manor, Junhong Zhou, Rachel Harrison, On-Yee Lo, Thomas G Travison, Jeffrey M Hausdorff, Alvaro Pascual-Leone, Lewis Lipsitz
OBJECTIVE: To determine the effects of a transcranial direct current stimulation (tDCS) intervention with the anode placed over the left dorsolateral prefrontal cortex (dlPFC) and cathode over the right supraorbital region, on cognition, mobility, and "dual-task" standing and walking in older adults with mild-to-moderate motor and cognitive impairments. METHODS: A double-blinded, block-randomized, sham-controlled trial was conducted in 18 nondemented, ambulatory adults aged ⩾65 years with slow walking speed (⩽1...
September 2018: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/30128947/anodal-frontal-tdcs-for-chronic-cluster-headache-treatment-a-proof-of-concept-trial-targeting-the-anterior-cingulate-cortex-and-searching-for-nociceptive-correlates
#12
Delphine Magis, Kevin D'Ostilio, Marco Lisicki, Chany Lee, Jean Schoenen
BACKGROUND: Percutaneous occipital nerve stimulation (ONS) is effective in refractory chronic cluster headache (rCCH) patients. Responders to ONS differ from non-responders by greater glucose metabolism in subgenual anterior cingulate cortex (sgACC). We reasoned that transcranial direct current stimulation (tDCS), a non-invasive approach, might be able to activate this area and thus improve rCCH patients. Our objective was to explore in a pilot trial the therapeutic potential of tDCS (anode at Fz, cathode over C7) and its possible effects on pain perception, frontal executive functions and mood in rCCH patients...
August 20, 2018: Journal of Headache and Pain
https://www.readbyqxmd.com/read/30110930/transcranial-direct-current-stimulation-tdcs-for-depression-during-pregnancy-scientific-evidence-and-what-is-being-said-in-the-media-a-systematic-review
#13
REVIEW
Anna Katharina Kurzeck, Beatrice Kirsch, Elif Weidinger, Frank Padberg, Ulrich Palm
Major depression is the most frequent morbidity in pregnancy. The first-line therapies, psychopharmacologic treatment and psychotherapy, are either insufficient or may cause severe or teratogenic adverse events. As a result of its local limitation to the patient's brain, transcranial direct current stimulation (tDCS) could potentially be an ideal treatment for pregnant women with depression. A literature search was conducted in medical databases, globally published newspapers, search engines, and clinical trial registers to collect all articles on tDCS for the treatment of depression during pregnancy...
August 14, 2018: Brain Sciences
https://www.readbyqxmd.com/read/30098657/transcranial-direct-current-stimulation-in-psychiatric-disorders-a-comprehensive-review
#14
REVIEW
Adriano H Moffa, Andre R Brunoni, Stevan Nikolin, Colleen K Loo
Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that has been gaining favor as a viable tool in Psychiatry. The purpose of this review is to summarize the evidence of tDCS as a treatment of disorders such as depression, schizophrenia, and obsessive-compulsive disorder (OCD). Current findings indicate that tDCS is probably effective in non-treatment-resistant depressive patients. Regarding schizophrenia and OCD, present evidence is not robust enough, although preliminary results indicate that tDCS is a promising technique...
September 2018: Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/30056141/transcranial-direct-current-stimulation-combined-with-cognitive-training-for-the-treatment-of-parkinson-disease-a-randomized-placebo-controlled-study
#15
Rosa Manenti, Maria Sofia Cotelli, Chiara Cobelli, Elena Gobbi, Michela Brambilla, Danila Rusich, Antonella Alberici, Alessandro Padovani, Barbara Borroni, Maria Cotelli
BACKGROUND: A number of non-motor symptoms occurs in Parkinson Disease (PD), cognitive decline and mood disturbances representing the most prevalent. Recent studies reported that cognitive training could potentially help to attenuate cognitive deficits in patients with PD and several researches demonstrated a beneficial effect of active transcranial Direct Current Stimulation (tDCS) over the left dorsolateral prefrontal cortex (anode over left dorsolateral prefrontal cortex, cathode over right supraorbital area) on cognitive deficits and mood disturbances...
July 18, 2018: Brain Stimulation
https://www.readbyqxmd.com/read/30019630/effects-of-electrical-stimulation-in-tinnitus-patients-conventional-versus-high-definition-tdcs
#16
Laure Jacquemin, Giriraj Singh Shekhawat, Paul Van de Heyning, Griet Mertens, Erik Fransen, Vincent Van Rompaey, Vedat Topsakal, Julie Moyaert, Jolien Beyers, Annick Gilles
BACKGROUND: Contradictory results have been reported for transcranial direct current stimulation (tDCS) as treatment for tinnitus. The recently developed high-definition tDCS (HD tDCS) uses smaller electrodes to limit the excitation to the desired brain areas. OBJECTIVE: The current study consisted of a retrospective part and a prospective part, aiming to compare 2 tDCS electrode placements and to explore effects of HD tDCS by matched pairs analyses. METHODS: Two groups of 39 patients received tDCS of the dorsolateral prefrontal cortex (DLPFC) or tDCS of the right supraorbital-left temporal area (RSO-LTA)...
August 2018: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29983706/test-retest-reliability-of-homeostatic-plasticity-in-the-human-primary-motor-cortex
#17
Tribikram Thapa, Siobhan M Schabrun
Homeostatic plasticity regulates synaptic activity by preventing uncontrolled increases (long-term potentiation) or decreases (long-term depression) in synaptic efficacy. Homeostatic plasticity can be induced and assessed in the human primary motor cortex (M1) using noninvasive brain stimulation. However, the reliability of this methodology has not been investigated. Here, we examined the test-retest reliability of homeostatic plasticity induced and assessed in M1 using noninvasive brain stimulation in ten, right-handed, healthy volunteers on days 0, 2, 7, and 14...
2018: Neural Plasticity
https://www.readbyqxmd.com/read/29974333/prefrontal-tdcs-attenuates-medial-prefrontal-connectivity-upon-being-criticized-in-individuals-scoring-high-on-perceived-criticism
#18
Josefien Dedoncker, Marie-Anne Vanderhasselt, Jonathan Remue, Sara De Witte, Guo-Rong Wu, Jill M Hooley, Rudi De Raedt, Chris Baeken
The mechanisms by which transcranial direct current stimulation (tDCS) influences emotional processing - and whether this is related to individual vulnerability for psychopathology - are still poorly understood. The present study aimed to investigate if one prefrontal tDCS session modulates mood and neural functional connectivity after being exposed to negative information differently in individuals low or high in perceived criticism (PC), which has been related to vulnerability for psychiatric illness. In a randomized cross-over design, one session of MRI-compatible prefrontal tDCS (neuronavigated placement of the anodal electrode at the left dorsolateral prefrontal cortex and the cathodal electrode at the right supraorbital region; vs...
July 4, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29967673/normal-electrical-activity-of-the-brain-in-obsessive-compulsive-patients-after-anodal-stimulation-of-the-left-dorsolateral-prefrontal-cortex
#19
Hamidreza Ghaffari, Ali Yoonessi, Mohammad Javad Darvishi, Akbar Ahmadi
Introduction: Transcranial Direct Current Stimulation (tDCS) has been used as a non-invasive method to increase the plasticity of brain. Growing evidence has shown several brain disorders such as depression, anxiety disorders, and chronic pain syndrome are improved following tDCS. In patients with Obsessive-Compulsive Disorder (OCD), increased brain rhythm activity particularly in the frontal lobe has been reported in several studies using Eectroencephalogram (EEG). To our knowledge, no research has been done on the effects of electrical stimulation on brain signals of patients with OCD...
March 2018: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/29950986/non-invasive-brain-stimulation-probing-intracortical-circuits-and-improving-cognition-in-the-aging-brain
#20
REVIEW
Joyce Gomes-Osman, Aprinda Indahlastari, Peter J Fried, Danylo L F Cabral, Jordyn Rice, Nicole R Nissim, Serkan Aksu, Molly E McLaren, Adam J Woods
The impact of cognitive aging on brain function and structure is complex, and the relationship between aging-related structural changes and cognitive function are not fully understood. Physiological and pathological changes to the aging brain are highly variable, making it difficult to estimate a cognitive trajectory with which to monitor the conversion to cognitive decline. Beyond the information on the structural and functional consequences of cognitive aging gained from brain imaging and neuropsychological studies, non-invasive brain stimulation techniques such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) can enable stimulation of the human brain in vivo , offering useful insights into the functional integrity of intracortical circuits using electrophysiology and neuromodulation...
2018: Frontiers in Aging Neuroscience
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