keyword
https://read.qxmd.com/read/38634154/enhancing-assisted-diagnostic-accuracy-in-scalp-psoriasis-a-multi-network-fusion-object-detection-framework-for-dermoscopic-pattern-diagnosis
#1
JOURNAL ARTICLE
Honghai Ji, Jiaqi Li, Xiaoyang Zhu, Lingling Fan, Weiwei Jiang, Yang Chen
BACKGROUND: Dermoscopy is a common method of scalp psoriasis diagnosis, and several artificial intelligence techniques have been used to assist dermoscopy in the diagnosis of nail fungus disease, the most commonly used being the convolutional neural network algorithm; however, convolutional neural networks are only the most basic algorithm, and the use of object detection algorithms to assist dermoscopy in the diagnosis of scalp psoriasis has not been reported. OBJECTIVES: Establishment of a dermoscopic modality diagnostic framework for scalp psoriasis based on object detection technology and image enhancement to improve diagnostic efficiency and accuracy...
April 2024: Skin Research and Technology
https://read.qxmd.com/read/38628046/therapeutic-textiles-a-promising-approach-for-human-skin-dysbiosis
#2
REVIEW
Cláudia Suellen Ferro de Oliveira, Freni Kekhasharú Tavaria
The close interaction between skin and clothing has become an attractive cornerstone for the development of therapeutic textiles able to alleviate skin disorders, namely those correlated to microbiota dysregulation. Skin microbiota imbalance is known in several skin diseases, including atopic dermatitis (AD), psoriasis, seborrheic dermatitis, rosacea, acne and hidradenitis suppurative (HS). Such microbiota dysregulation is usually correlated with inflammation, discomfort and pruritus. Although conventional treatments, that is, the administration of steroids and antibiotics, have shown some efficacy in treating and alleviating these symptoms, there are still disadvantages that need to be overcome...
April 2024: Experimental Dermatology
https://read.qxmd.com/read/38613429/sebaceous-gland-atrophy-due-to-seborrheic-dermatitis-in-a-patient-with-alopecia-a-potential-pitfall
#3
Sena Zengin, Jacey Guthrie, Nicholas Zoumberos, Mugahed Hamza, Sara C Shalin
Seborrheic dermatitis is an inflammatory condition that usually presents with erythema, scaly greasy papules, and plaques affecting sebaceous gland-rich areas and predominantly involving the face and scalp. The diagnosis of seborrheic dermatitis can often be rendered based on the clinical presentation. However, in certain cases, a biopsy can be useful to distinguish it from clinical mimics such as psoriasis, discoid lupus, and rosacea. Prominent sebaceous gland atrophy without scarring has been well-described as an important and relatively specific clue for psoriatic or drug-induced alopecia...
April 13, 2024: Journal of Cutaneous Pathology
https://read.qxmd.com/read/38612631/zinc-copper-and-iron-in-selected-skin-diseases
#4
REVIEW
Aleksandra Podgórska, Aleksandra Kicman, Sylwia Naliwajko, Marta Wacewicz-Muczyńska, Marek Niczyporuk
Trace elements are essential for maintaining the body's homeostasis, and their special role has been demonstrated in skin physiology. Among the most important trace elements are zinc, copper, and iron. A deficiency or excess of trace elements can be associated with an increased risk of skin diseases, so increasing their supplementation or limiting intake can be helpful in dermatological treatment. In addition, determinations of their levels in various types of biological material can be useful as additional tests in dermatological treatment...
March 29, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38601387/interprofessional-collaboration-differentiating-netherton-syndrome-and-atopic-dermatitis-in-an-african-american-infant
#5
Erin G Park, Kylie Besly, Juan J Campos, Ahmed Rezk
Netherton syndrome is a rare, autosomal recessive disorder that clinically presents with a triad of congenital ichthyosiform erythroderma, hair shaft abnormalities, and immune dysregulation, which is confirmed with genetic testing for mutations in the serine protease inhibitor Kazal-type 5 (SPINK5) gene. This diagnosis was included in our differential due to the patient's recurring and unimproving rash with desquamating skin. While eczema was included in our differential diagnoses, the patient's systemic symptoms, including failure to thrive, prompted our team to consider other diagnoses...
March 2024: Curēus
https://read.qxmd.com/read/38593092/impact-of-ketogenic-and-low-glycemic-diets-on-inflammatory-skin-conditions
#6
REVIEW
Katie Roster, Lillian Xie, Terry Nguyen, Shari R Lipner
Diet plays an emerging role in dermatologic therapy. The ketogenic and low-glycemic diets have potential anti-inflammatory and metabolic effects, making them attractive for treating inflammatory skin conditions. We provide an overview of the current evidence on the effects of ketogenic and low-glycemic diets on inflammatory skin conditions including acne, psoriasis, seborrheic dermatitis (SD), atopic dermatitis (AD), and hidradenitis suppurativa (HS). We conclude that low-glycemic diets show promise for treating acne, while the evidence for ketogenic diets in treating other inflammatory skin conditions is limited...
February 2024: Cutis; Cutaneous Medicine for the Practitioner
https://read.qxmd.com/read/38576246/facial-dermatoses-associated-with-mask-wearing-in-the-covid-19-era-a-nationwide-cross-sectional-multicenter-questionnaire-based-study
#7
JOURNAL ARTICLE
Myoung Eun Choi, Woo Jin Lee, Joo Yeon Ko, Kwang Joong Kim, Jung Eun Kim, Hei Sung Kim, Kui Young Park, Mi Youn Park, Dae Hun Suh, Kihyuk Shin, Min Kyung Shin, Hyo Hyun Ahn, Weon Ju Lee, Jee Bum Lee, Hee Jung Lee, Min Soo Jang, Seung Hyun Cheong, Soyun Cho, Yu Sung Choi, You Won Choi, Hoon Choi, Mi Woo Lee
BACKGROUND: Daily usage of facial masks during coronavirus disease 2019 pandemic influenced on facial dermatoses. OBJECTIVE: This study investigated the impact of mask-wearing habits on facial dermatoses. METHODS: A nationwide, observational, questionnaire-based survey was conducted from July through August 2021, involving 20 hospitals in Korea. RESULTS: Among 1,958 facial dermatoses, 75.9% of patients experienced aggravation or development of new-onset facial dermatoses after wearing masks...
April 2024: Annals of Dermatology
https://read.qxmd.com/read/38576147/roflumilast-foam-zoryve-for-seborrheic-dermatitis
#8
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
April 15, 2024: Medical Letter on Drugs and Therapeutics
https://read.qxmd.com/read/38572028/is-seborrheic-keratosis-really-benign-a-case-report-of-seborrheic-keratosis-with-malignant-transformation
#9
JOURNAL ARTICLE
Aishwarya Muddebihal, Ayesha Khatoon, Sandip Mohanty
No abstract text is available yet for this article.
2024: Indian Journal of Dermatology
https://read.qxmd.com/read/38563541/-clinical-therapeutic-and-pathophysiological-aspects-of-darier-s-disease
#10
JOURNAL ARTICLE
Pauline Bernard, Maël Blanchard, Marie-Anne Morren, Emmanuella Guenova
Darier Disease is a rare autosomal dominant inherited skin disorder classified as an acantholytic dermatosis. It manifests around puberty as brownish keratotic papules of skin folds and seborrheic areas, associated with onychopathy and mucosal involvementand have a chronic relapsing-remitting course with frequent exacerbations triggered by sun exposure, heat, friction, or infections. Darier patients have an increased risk of neuropsychiatric disorders, type 1 diabetes and heart failure. Short-term management relies on antibiotics/antiviral, topical corticosteroids and/or retinoids...
March 27, 2024: Revue Médicale Suisse
https://read.qxmd.com/read/38563487/recurrent-inverse-necrotizing-infundibular-crystalline-folliculitis
#11
Marina Kristy Ibraheim, Leslie Storey, Jeffrey P North
Necrotizing infundibular crystalline folliculitis (NICF) is a rare type of necrotizing folliculitis. The disease typically manifests as folliculocentric papules arising in a seborrheic distribution. Only 23 cases exist in the literature. Most reported cases have arisen spontaneously, but a small number of drug-induced cases in the setting of epidermal-derived growth factor, vascular endothelial-derived growth factor, or PD-1 inhibitor therapy have been reported. Colonization by bacteria and/or yeast occurs frequently...
April 2, 2024: Journal of Cutaneous Pathology
https://read.qxmd.com/read/38546769/improving-access-to-dermatology-specialist-care-review-of-a-dermatologist-and-general-practitioner-integrated-clinic-model
#12
JOURNAL ARTICLE
Neakiry Kivi, Louise Reiche, Tanira Kingi, Christina Elder, Alex Semprini
Introduction This study presents an innovative model of integrated dermatology service delivery. Kauri HealthCare (KHC) is a general practice serving around 19 000 patients in Palmerston North, New Zealand. A 'mini clinic' is provided by an on-site dermatologist that is available for patients of KHC. Referring practitioners are required to attend with the patient to present their case and seek dermatologist input. This allows for patients to receive a specialist opinion, as well as for the referrer to receive practical and academic teaching, record findings, and arrange any further investigations, follow-up, or management...
March 2024: Journal of Primary Health Care
https://read.qxmd.com/read/38543166/-cassia-alata-l-a-study-of-antifungal-activity-against-malassezia-furfur-identification-of-major-compounds-and-molecular-docking-to-lanosterol-14-alpha-demethylase
#13
JOURNAL ARTICLE
Nyi Mekar Saptarini, Resmi Mustarichie, Silviana Hasanuddin, Mary Jho-Anne Tolentino Corpuz
Empirically, in Indonesia, the leaves of Cassia alata L. (candle bush or ketepeng cina) have been used as a topical antifungal agent. Malassezia furfur is a natural microorganism found in the human body. It is among the factors contributing to conditions such as pityriasis versicolor, a common, benign, superficial fungal infection of the skin that is closely associated with seborrheic dermatitis and dandruff. This study aimed to explore C. alata leaves, starting from determining antifungal activity against M...
March 16, 2024: Pharmaceuticals
https://read.qxmd.com/read/38542014/dermoscopy-of-umbilical-lesions-a-systematic-review
#14
REVIEW
Jakub Żółkiewicz, Martyna Sławińska, Urszula Maińska, Roman J Nowicki, Michał Sobjanek, Luc Thomas
Background : The umbilicus is a fibrous remnant located in the centre of the abdomen. Various entities may be encountered in this special anatomical location; however, little is known about their dermoscopic presentation. The aim of this study was to provide a comprehensive summary of existing evidence on dermoscopic features of umbilical lesions. Methods : Studies assessing dermoscopic images of umbilical lesions were included in this study. No age, ethnicity or skin phototype restrictions were applied. Papers assessing lesions outside of the umbilical area, lacking dermoscopic images and/or dermoscopic description and not related to the topic were excluded...
March 20, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38536168/persistent-cutaneous-lesions-of-darier-disease-and-second-hit-somatic-variants-in-atp2a2-gene
#15
JOURNAL ARTICLE
Lihi Atzmony, Fadia Zagairy, Banan Mawassi, Majd Shehade, Yasmin Tatour, Nada Danial-Farran, Morad Khayat, Nassim Warrour, Roni Dodiuk-Gad, Eran Cohen-Barak
IMPORTANCE: Darier disease (DD) is a rare genetic skin disorder caused by heterozygous variants in the ATP2A2 gene. Clinical manifestations include recurrent hyperkeratotic papules and plaques that occur mainly in seborrheic areas. Although some of the lesions wax and wane in response to environmental factors, others are severe and respond poorly to therapy. OBJECTIVE: To investigate the molecular mechanism underlying the persistency of skin lesions in DD. DESIGN, SETTING, AND PARTICIPANTS: In this case series, DNA was extracted from unaffected skin, transient and persistent lesional skin, and blood from 9 patients with DD...
March 27, 2024: JAMA Dermatology
https://read.qxmd.com/read/38527980/immunoexpression-of-ki67-p16-and-beta-catenin-in-precursor-lesions-of-cutaneous-squamous-cell-carcinoma
#16
JOURNAL ARTICLE
Alina Maria Vîlcea, Loredana Elena Stoica, Bianca Cătălina Andreiana, Cecil Sorin Mirea, Tiberiu Ştefăniţă Ţenea Cojan, Ioana Cristina Vîlcea, Claudiu Mărgăritescu
Cutaneous squamous cell carcinoma (CSCC) is the second most common type of skin cancer, after basal cell carcinoma, representing about 10-20% of all malignant skin tumors. The mortality rates of CSCC approach those of renal and oropharyngeal carcinomas, as well as melanoma, with the increasing of the risk once metastases and perineural invasion occur. Both actinic keratosis (AK) and Bowen's disease (BD) are direct precursors with the potential for progression to CSCC. In this study, we analyzed the expression of Ki67, P16 and Beta-catenin in the precursor lesions of CSCC in relation to histological prognostic parameters, respectively between them, with the aim of identifying possible correlations with a role in prognosis...
2024: Romanian Journal of Morphology and Embryology
https://read.qxmd.com/read/38524395/use-of-topical-corticosteroids-in-the-treatment-of-noninfectious-inflammatory-dermatoses-of-the-scalp-a-survey-of-practicing-dermatologists-and-dermatology-residents-using-delphi-methodology
#17
JOURNAL ARTICLE
Juan Francisco Mir-Bonafé, Jaime Piquero-Casals, Ludmila Prudkin, Jesus Delgado, Julia Santamaria Martínez, Vicente Garcia-Patos Briones
BACKGROUND: Noninfectious inflammatory dermatoses of the scalp are common, and their symptomsin particular, those affecting appearance, can have a psychological effect that may be disproportionate to their clinical severity. Effective, cosmetically acceptable treatments are important to manage these conditions. Topical corticosteroids form the cornerstone of acute treatment for many of these conditions. We surveyed practicing dermatologists and dermatology residents to determine the current clinical practice in prescribing topical corticosteroids for these disorders in their various preparation formats...
2024: Clinical, Cosmetic and Investigational Dermatology
https://read.qxmd.com/read/38513115/onychocytic-matricoma-a-clinical-dermoscopic-and-pathological-analysis-of-14-cases
#18
JOURNAL ARTICLE
Christophe Perrin, Michael Coutts, Feriel Boukari, Damien Ambrosetti
Onychocytic matricoma (OCM) is a benign neoplasm of the nail matrix. Only 18 cases of this tumor have been reported in the literature to date. We retrospectively analyzed the clinical features of 14 patients with OCM. The most common clinical feature was longitudinal xanthopachyonychia (n = 9), followed by longitudinal leukopachyonychia (=3) and longitudinal pachymelanonychia (n = 2). The most common clinical findings identified following dermoscopy and analysis at high magnification of classical photographs were free-edge thickening of the nail plate without pitting (n = 14), longitudinal ridging (n = 7), round white clods (n = 7), white dots (n = 7), and filiform hemorrhages (n = 7), followed by oval and linear white clods (n = 5), fuzzy lateral border (n = 5), and red-purple blood clods (n = 3)...
March 19, 2024: American Journal of Dermatopathology
https://read.qxmd.com/read/38478647/red-crusty-plaques-in-a-young-man
#19
JOURNAL ARTICLE
Mishma Farsi, Cassandra M Johnson, Kelly Segars, Jonathan Rhim
Pemphigus foliaceus is a superficial blistering disorder characterized by erosions and scaling in a seborrheic distribution. The condition typically occurs in healthy individuals but issues arise from delayed diagnosis. Many cases remain undiagnosed or misdiagnosed due to the lack of awareness of the condition. With use of common diagnostic tools, pemphigus foliaceus can be easily identified and monitored. Histological analysis exhibits "chicken wire" patterning along keratinocytes in the upper epidermis, whereas immunofluorescence study displays subcorneal acantholysis...
October 15, 2023: Dermatology Online Journal
https://read.qxmd.com/read/38472524/more-yeast-more-problems-reevaluating-the-role-of-malassezia-in-seborrheic-dermatitis
#20
REVIEW
Christy H Chang, Raj Chovatiya
Seborrheic dermatitis (SD) is an inflammatory skin disorder and eczema subtype increasingly recognized to be associated with significant physical, psychosocial, and financial burden. The full spectrum of SD, including dandruff localized to the scalp, is estimated to affect half of the world's population. Despite such high prevalence, the exact etiopathogenesis of SD remains unclear. Historically, many researchers have theorized a central, causative role of Malassezia spp. based on prior studies including the proliferation of Malassezia yeast on lesional skin of some SD patients and empiric clinical response to antifungal therapy...
March 12, 2024: Archives of Dermatological Research
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