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Priyanka Singh, How Chuan Han
Labial adhesion is defined as complete or partial fusion of the labia minora in the midline through flimsy or dense adhesions. It may be congenital or acquired. Acquired cases are mainly seen in oestrogen deficiency states in prepubertal girls and postmenopausal women. Aggravating factors include chronic inflammation due to poor hygiene, eczema, lichen planus or sclerosus, seborrhic dermatitis, eczema, local trauma and recurrent urinary tract infections. Patients may be asymptomatic or present with urinary or vulval symptoms...
November 28, 2018: International Urogynecology Journal
Mark L Dreher
Less than 10% of most Western populations consume adequate levels of whole fruits and dietary fiber with typical intake being about half of the recommended levels. Evidence of the beneficial health effects of consuming adequate levels of whole fruits has been steadily growing, especially regarding their bioactive fiber prebiotic effects and role in improved weight control, wellness and healthy aging. The primary aim of this narrative review article is to examine the increasing number of health benefits which are associated with the adequate intake of whole fruits, especially fruit fiber, throughout the human lifecycle...
November 28, 2018: Nutrients
Andrew T Gabrielson, Tan V Le, Christopher Fontenot, Mustafa Usta, Wayne J G Hellstrom
INTRODUCTION: The dermatologic conditions affecting the male genitalia are diverse and range from normal variants and benign growths to overt malignancy. Unfortunately, there is a dearth of urologic dermatology training in most residency programs, and many dermatologic lesions with a classic appearance on other areas of the body may have atypical presentations on the genitalia. Patients may present to a variety of physicians without receiving a definitive diagnosis, which can be highly distressing to the afflicted individual...
November 17, 2018: Sexual Medicine Reviews
Amirreza Mahbod, Gerald Schaefer, Isabella Ellinger, Rupert Ecker, Alain Pitiot, Chunliang Wang
Malignant melanoma is one of the most aggressive forms of skin cancer. Early detection is important as it significantly improves survival rates. Consequently, accurate discrimination of malignant skin lesions from benign lesions such as seborrheic keratoses or benign nevi is crucial, while accurate computerised classification of skin lesion images is of great interest to support diagnosis. In this paper, we propose a fully automatic computerised method to classify skin lesions from dermoscopic images. Our approach is based on a novel ensemble scheme for convolutional neural networks (CNNs) that combines intra-architecture and inter-architecture network fusion...
November 3, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
Sha-Sha Yu, Yun Zhao, Hong Zhao, Jin-Yong Lin, Xin Tang
AIM: To describe the histopathologic and clinical features of eyelid tumor cases from Tianjin Eye Hospital during 2002 to 2015. METHODS: In this retrospective study, a total of 2228 cases of eyelid tumors with pathologic diagnoses were enrolled. The eyelid tumors were classified into three groups according to tumor origin: epidermal, adnexal and miscellaneous, including melanocytic, neural and vascular lesions. Inflammatory tumor-like lesions were excluded. The clinical characteristics of the eyelid tumors were analyzed, including age, gender and lesion location...
2018: International Journal of Ophthalmology
Xulei Yang, Hangxing Li, Li Wang, Si Yong Yeo, Yi Su, Zeng Zeng
Automatic skin lesion analysis involves two critical steps: lesion segmentation and lesion classification. In this work, we propose a novel multi-target deep convolutional neural network (DCNN) to simultaneously tackle the problem of segmentation and classification. Based on U-Net and GoogleNet, a single model is constructed with three different targets of both lesion segmentation and two independent binary lesion classifications (i.e., melanoma detection and seborrheic keratosis identification), aiming to explore the differences and commonalities over different target models...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
M Molina Anguita, F Abadín López, L Márquez Quero, A M Merino González, M J Salve Diaz Miguel
OBJECTIVE: To determine the degree of correlation between the clinical diagnosis prior to the minor surgery process and its concordance with the results of histopathology report, as well as to determine the surgical data of little clinical importance compared to that which is really necessary and cost-effective. MATERIAL AND METHOD: A descriptive, observational, retrospective and transversal study was conducted of the Minor Surgery Activities of a clinic in the Ciudad Real Health Centre I...
November 8, 2018: Semergen
(no author information available yet)
No abstract text is available yet for this article.
September 24, 2018: Medical Letter on Drugs and Therapeutics
D Boehmer, K Eyerich
No abstract text is available yet for this article.
November 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
Stacy R Smith, Shuai Xu, Esther Estes, Stuart D Shanler
OBJECTIVE: Seborrheic keratoses (SKs) may present in any non-glabrous skin, but data are limited on the response to treatment as based on the SK location. We aimed to understand the relationship between SK location and clearance with up to 2 treatments of 40% (w/w) hydrogen peroxide topical solution (HP40). METHODS: We conducted a sub-analysis of data pooled from two randomized, double-blind, vehicle (VEH)-controlled clinical trials, including 937 patients, each with 4 target SKs (N=3,748 SKs), with at least 1 on the face and 1 on the trunk or extremities...
October 1, 2018: Journal of Drugs in Dermatology: JDD
Tongyu C Wikramanayake, Penelope Hirt, Maram Almastadi, Hunter Mitchell, Marjana Tomic-Canic, Laura Romero, Denisse Garcia, Natasa Strbo
Seborrheic Dermatitis (SD) is a common inflammatory skin disorder, but its molecular pathogenesis remains elusive. Previously, we have established the Mpzl3 knockout (-/-) mice as a model for SD. In this study, we focused on early phases of skin inflammation and determined the cytokine profiles and identified immune cell types in the lesional skin in the Mpzl3 -/- mice. Using flow cytometry, we detected significant increase of CD45+ leukocytes, CD3+ T lymphocytes and especially γδ T cells but not αβ T cells in the lesional skin compared to control...
October 11, 2018: Experimental Dermatology
Lindsey West, Matthew Carlson, Luke Wallis, Heather W Goff
BACKGROUND: The sign of Leser-Trelát is controversial and rarely reported in gynecologic malignancies. It is characterized by rapid development of new or enlarging seborrheic keratoses. CASE: A 78-year-old woman presented with unintentional weight loss and new-onset erythematous patches and plaques with thickened, rugated skin and stuck-on brown waxy papules on the chest and back. Her symptoms were concerning for a paraneoplastic eruption; workup revealed an elevated CA 125 level and an ovarian mass on abdominal computed tomography scan...
October 5, 2018: Obstetrics and Gynecology
Anna Kołodziejczak, Angelika Wieczorek, Helena Rotsztejn
OBJECTIVE: The aim of this study was to assess objectively the effects of the combination of corundum microdermabrasion and cavitation peeling in the therapy of seborrheic skin with visible symptoms of acne punctata. MATERIAL AND METHODS: The study involved a group of nine women. A series of six treatments with the combination of microdermabrasion and cavitation peeling were performed within facial skin at 10-14 days intervals. Corneometric measurements examining skin hydration level and sebumetric measurements analyzing skin sebum level were made before the series of treatments and after second, fourth and sixth procedure in five facial areas...
October 9, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Thomas George Olsen, B Hunter Jackson, Theresa Ann Feeser, Michael N Kent, John C Moad, Smita Krishnamurthy, Denise D Lunsford, Rajath E Soans
Background: Artificial intelligence is advancing at an accelerated pace into clinical applications, providing opportunities for increased efficiency, improved accuracy, and cost savings through computer-aided diagnostics. Dermatopathology, with emphasis on pattern recognition, offers a unique opportunity for testing deep learning algorithms. Aims: This study aims to determine the accuracy of deep learning algorithms to diagnose three common dermatopathology diagnoses...
2018: Journal of Pathology Informatics
Bruno Gualtieri, Salvatore Panduri, Andrea Chiricozzi, Marco Romanelli
No abstract text is available yet for this article.
September 20, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
Bareqa Salah, Mohamad Mahseeri, Zaid Al-Ali, Ata Gaith, Tareq Aldwan, Baeth Al-Rawashdeh
INTRODUCTION: Seborrheic keratosis is one of the most common benign epidermal cutaneous lesions encountered by dermatologists and plastic surgeons in their daily practice. PRESENTATION OF THE CASE: A 66-year-old man was presented with a large verrucous mass on the sacrum and perianal area of 10 years duration. After the diagnosis of SK was confirmed, a complete excision of the lesion was done with coverage of the defect with a partial thikness skin graft, with a good outcome...
2018: International Journal of Surgery Case Reports
Stephanie Kao, Alexi Kiss, Tatiana Efimova, Adam J Friedman
Seborrheic keratosis (SK) is the most common skin tumor seen by dermatologists in everyday practice. Although the lesions are mostly benign, many patients still elect to have asymptomatic SK removed. The historical standards of treatment are cryosurgery and electrocautery, two surgical options that are effective at lesion removal but have high rates of postoperative adverse events such as treatment-site scarring and pigmentary alterations. The cosmetic outcomes of SK treatment modalities are of keen interest to dermatologists, as the American population becomes increasingly more diverse...
September 1, 2018: Journal of Drugs in Dermatology: JDD
Daniel Flood, Amanda Lezanski-Gujda, Nathanial R Miletta
Pemphigus foliaceus (PF) is an autoimmune dermatologic disease that typically presents with painful, superficial blisters that evolve into scaling erosions in a seborrheic distribution. This case study intends to demonstrate that due to the relative scarcity of the disease and its distribution on the body, PF can easily be misdiagnosed. We present a 43-year-old African American male that presented to the dermatology clinic with an 18-month history of non-pruritic, violaceous, scaling patches and plaques most prominent on the malar cheeks, upper chest and upper back...
September 12, 2018: Military Medicine
Heidi Oi-Yee Li, Sophia Colantonio, Nordau Kanigsberg
Darier's disease, an autosomal dominant genodermatosis, arises from a mutation in the ATP2A2 gene that codes for sarco/endoplasmic reticulum Ca2+ -ATPase in the endoplasmic reticulum and is characterized by greasy keratotic papules commonly found in seborrheic regions. Conventional treatments, including topical corticosteroids, antibiotics, antifungals and retinoids, often have limited efficacy. The present article reports the novel use of oral magnesium chloride supplementation (300 mg daily) in the treatment of Darier disease...
2018: SAGE Open Medical Case Reports
N Brankov, R Z Conic, N Atanaskova-Mesinkovska, M Piliang, W F Bergfeld
Background: Lichen planopilaris (LPP) is a rare, cicatricial, lymphocyte-mediated alopecia that is thought to have an autoimmune pathogenesis and possibly related to other autoimmune diseases. However, data are limited and studies that examine comorbid conditions are lacking. Objectives: We sought to determine the prevalence of systemic comorbid conditions, nutritional deficiencies, psychological problems, and skin cancers in patients with LPP. Methods: We identified 334 patients with LPP who were seen in the Department of Dermatology at the Cleveland Clinic Foundation between 2000 and 2016...
September 2018: International Journal of Women's Dermatology
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