Read by QxMD icon Read

2D Analysis

Yawen Hong, Tiejin Ying
A water-soluble polysaccharide WSP1 was extracted from the fruiting body of Termitornyces albuminosus. Its molecular weight, monosaccharide composition and molecular structure were determined by GPC, GC-MS, UV spectroscopy, FT-IR spectroscopy, methylation analysis, NMR (1D and 2D) and AFM. Moreover, the antioxidant activity of WSP1 was evaluated in vitro by the tests of reducing power, scavenging ability on DPPH radical and hydroxyl radical, and chelating ability on ferrous ion. The results indicated that the molecular weight of WSP1 was 9 kDa, and it was mainly composed of fucose and galactose in a molar ratio of 1:3...
October 13, 2018: International Journal of Biological Macromolecules
Liyang Jia, Gehong Su, Qiang Yuan, Xueqian Zhang, Tao Zhou
The difference in the micro-dynamics mechanism between aromatic nylon and aliphatic nylon during water absorption was studied to explore the reason for the significantly smaller decline of barrier performance of poly(m-xylene adipamide) (MXD6) film than that of polyamide 6 (PA6) film under high humidity. Attenuated total reflection (ATR) FTIR, combined with scaling moving-window 2D correlation spectroscopy (scaling-MW2D) and generalized 2D correlation analysis, was used. The scaling-MW2D confirmed that the water absorption of MXD6 comprises two processes, designated process I (2...
October 16, 2018: Physical Chemistry Chemical Physics: PCCP
Maryam Ranjpour, Saima Wajid, Swatantra Kumar Jain
Identification of events leading to HCC progression is essential for understanding its pathophysiology. Present study was designed to identify differentially expressed proteins in serum of HCC-bearing rats vis-a-vis controls during cancer initiation, progression and tumorigenesis. HCC was chemically induced by administering N-Nitrosodiethylamine and 2-aminoacetylfluorine to male Wistar rats. Carcinogen administration caused inflammation leading to liver injury and HCC development. Liver inflammation was confirmed by increase in levels of IL-6 and TNF-α in carcinogen treated rats...
October 15, 2018: Anti-cancer Agents in Medicinal Chemistry
Youli Qiu, Yu Li
A highly sensitive method for the detection of phthalate acid ester (PAE) derivatives by fluorescence spectroscopy based on a double-substitution modification is reported. The fluorescence intensities of 18 PAE derivatives and the template PAEs after docking with the protein bovine serum albumin (BSA) are compared; the fluorescence intensities of the PAE derivatives increase significantly (28.20 to 110.00 times) with high sensitivities, but the functionalities (stability and insulation) are not affected. The persistence, mobility, and toxicity of the PAE derivatives are reduced by varying degrees, and their amounts of bioaccumulation are not significantly changed, indicating that the derivatives are more environmentally friendly...
October 15, 2018: Environmental Science and Pollution Research International
Gopinath Danda, Marija Drndić
Two-dimensional (2D) materials from graphene to metal dichalcogenides and beyond, have interesting electrical, optical and mechanical properties. Recent advances in their growth, transfer and device physics have led to the shrinking of 2D material-based devices to the atomic scale and expanding their functionality. Single or multiple nanometer-scale holes, as small as single-atom vacancies, can be introduced in suspended atomically-thin 2D membranes, giving rise to nanopore and nanoporous devices, respectively...
October 12, 2018: Current Opinion in Biotechnology
Sushant Kumar Behera, Pritam Deb
The first-order standard perturbation theory combined with ab initio projector augmented wave operator challenges the realization of the standard Sternheimer equation with linear computational efficiency. This efficiency motivates us to describe the electron-phonon interaction in a two-dimensional (2D) black phosphorous monolayer using generalized density functional perturbation theory (DFPT) with Boltzmann transport theory (BTE). Subsequently, linear response phonon dynamic behaviours in terms of conductivities, Seebeck coefficients and transport properties are studied for the thermoelectric application...
October 15, 2018: Physical Chemistry Chemical Physics: PCCP
Maciej Majka, Albrecht Serfling, Paweł Czembor, Aurelia Ślusarkiewicz-Jarzina, Michał Tomasz Kwiatek, Frank Ordon, Halina Wiśniewska
Leaf rust caused by Puccinia triticina Eriks belongs to the most important fungal pathogens of wheat ( Triticum aestivum L.) and triticale (× Triticosecale ). Effective resistance to leaf rust is both, cost-effective and environmentally safe. Many wild Aegilops species carry unknown resistances against fungal diseases and are characterized by a high genetic variability. The main goal of this work was to examine the resistance of ( Aegilops tauschii × Secale cereale ) × Triticosecale hybrids to leaf rust in inoculation tests with different races of P ...
2018: Frontiers in Plant Science
Martina Bonacini, Alessandra Soriano, Alessandro Zerbini, Eleonora Calò, Luca Cimino, Francesco Muratore, Luigi Fontana, Luca Braglia, Maria Parmeggiani, Carlo Salvarani, Stefania Croci
Behçet disease (BD) is an inflammatory systemic disease with a fluctuating course, which can affect the skin, eyes, central nervous system, musculoskeletal, gastrointestinal, and vascular systems. No laboratory tests are currently available for the diagnosis of BD and monitoring disease activity. Moreover there is a lack of knowledge on BD pathogenesis. This study focused on circulating Natural Killer (NK), NKT and T cells evaluated as CD3neg CD56pos , CD3pos CD56pos , and CD3pos CD56neg . Peripheral blood mononuclear cells (PBMCs) were collected from 38 BD patients and 20 healthy controls (HC)...
2018: Frontiers in Immunology
Michael Weißl, Thomas Rath, Jürgen Sattelkow, Harald Plank, Samuel Eyley, Wim Thielemans, Gregor Trimmel, Stefan Spirk
A generic procedure for the manufacturing of cellulose-metal sulfide multilayered sandwich type thin films is demonstrated at the example of copper indium sulfide. These multilayers were created by alternate spin coating steps of precursors, followed by their conversion using either acidic vapors, or heat treatment. As precursors, cellulose xanthate, a widely available cellulose derivative employed in viscose fiber manufacturing and commercial copper and indium xanthates were used. After conversion of the single layers into cellulose and copper indium sulfide, the film properties (structure, thickness, photoelectric activity) of the single and multilayer systems consisting of alternate layers of cellulose and copper indium sulfide were studied...
January 1, 2019: Carbohydrate Polymers
N Ramalakshmi, A Puratchikody, Vignesh Muralidharan, Mukesh Doble, Arunkumar Subramani
The Quantitative structure activity relationship for thirty two novel substituted quinoxalines was performed for their antitubercular (Mycobacterium tuberculosis H37Rv) and antileptospiral (Leptospirainterrogans) activities. The quinoxalines were substituted with azetidinones, thiazolidinones and fluoroquinolones. Several compounds exhibited good activity against both the infections and they all possess fluoroquinolone moiety with the quinoxaline. The models developed showed good linear relationship (r2 = 0...
October 11, 2018: Current Computer-aided Drug Design
Mary Rajathei David, Parthasarathy Subbiah, Selvaraj Samuel
BACKGROUND: Vortioxetine is a multimodal antidepressant drug with combined effects on SERT as inhibitor, 5-HT1A as agonist and 5-HT3A as antagonist. Series of vortioxetine analogs have been reported as multi antidepressant compounds and they block serotonin transport into the neuronal cells, activate the postsynaptic 5-HT1A receptors and eliminate the low activity of 5-HT3A receptors. OBJECTIVE: To explore the important properties of vortioxetine analogs involved in antidepressant activity by developing 2D QSAR models...
October 11, 2018: Current Computer-aided Drug Design
Ali Afzali, Farshid Babapour Mofrad, Majid Pouladian
Detailed knowledge of anatomical lung variation is very important in medical image processing. Normal variations of lung consistent with the maintenance of pulmonary health and abnormal lung variations can be as a result of a pulmonary disease. Inter-patient lung variations can be due to the several factors such as sex, age, height, weight and type of disease. This study tries to show the inter-patient lung variations by using one of the shape-based descriptions techniques which is called Fourier descriptors...
October 13, 2018: Journal of Medical Systems
Shaun R Yockelson, Stephen B Heitner, Sarah Click, Gemechu Geleto, Miriam M Treggiari, Michael P Hutchens
OBJECTIVE: An association between central venous pressure and acute kidney injury (AKI) has been observed following cardiac surgery, but it is unknown whether this reflects intravascular volume status or impaired right ventricular (RV) myocardial performance. This study was performed to test the hypothesis that decreased RV peak longitudinal strain (PLSS), as measured by 2-dimensional speckle-tracking echocardiography, is associated with AKI following cardiac surgery. DESIGN: Retrospective observational cohort study...
September 12, 2018: Journal of Cardiothoracic and Vascular Anesthesia
Ferhat Can Özkaya, Weaam Ebrahim, Mona El-Neketi, T Tansel Tanrıkul, Rainer Kalscheuer, Werner E G Müller, Zhiyong Guo, Kun Zou, Zhen Liu, Peter Proksch
A comparative study on the metabolic profile of the sponge-associated fungus Aspergillus carneus using the OSMAC approach was conducted. The fungal strain was fermented on three different media including solid rice medium with or without sea salt and modified Czapek medium. Three new natural products, isopropylchaetominine (1), isoterrelumamide A (2) and 5'-epi-averufanin (3), together with fourteen known compounds (4-17) were isolated. The structures of the new compounds were established by 1D and 2D NMR spectroscopic analysis as well as by HRESIMS...
October 9, 2018: Fitoterapia
Dalton T Snyder, Lucas J Szalwinski, J Mitchell Wells, R Graham Cooks
A new set of operations for tandem mass spectrometry in a linear ion trap is described. Logical MS/MS operations categorize compounds in mixtures based on characteristic structural features as revealed by MS/MS behavior recorded in multiple fragmentation pathways. This approach is a conceptual extension of tandem mass spectrometry in which interrogation of the full data domain is performed by simultaneous implementation of precursor and neutral loss scans. This process can be thought of as moving through the 2D MS/MS data domain along multiple scan lines simultaneously, which allows experiments that explore the 2D data domain of MS/MS to be couched in terms of logical operations, AND, NAND (not and), OR (inclusive or), XOR (exclusive or), NOT, etc...
October 12, 2018: Analyst
Bhawna Dhruv, Neetu Mittal, Megha Modi
Medical field has highly evolved with advancements in the technologies which prove to be beneficial for radiologists and patients for better diagnosis. The era of medical science provides best healthcare solutions with the help of medical images. Till now, 2D MRIs played a prominent role in early detection of disease but with latest technologies taking over the charge, 3D MRIs are highly effective and great in demand now-a-days. With the aid of advanced techniques such as edge detection, segmentation and texture analysis on these images the disease detection may become much easier...
October 12, 2018: International Journal of Neuroscience
Yucheng Fu, Rong Liu, Yang Liu, Jiawei Lu
Understanding intertrochanteric fracture distribution is an important topic in orthopedics due to its high morbidity and mortality. The intertrochanteric fracture can contain high-dimensional information including complicated 3D fracture lines, which often make it difficult to visualize or to obtain valuable statistics for clinical diagnosis and prognosis applications. This paper proposed a map projection technique to map the high-dimensional information into a 2D parametric space. This method can preserve the 3D proximal femur surface and structure while visualizing the entire fracture line with a single plot/view...
October 12, 2018: Medical & Biological Engineering & Computing
Krithika Hariharan, Harald Stachelscheid, Bella Rossbach, Su-Jun Oh, Nancy Mah, Kai Schmidt-Ott, Andreas Kurtz, Petra Reinke
Human pluripotent stem cells (hPSCs) provide a source for the generation of defined kidney cells and renal organoids applicable in regenerative medicine, disease modeling, and drug screening. These applications require the provision of hPSC-derived renal cells by reproducible, scalable, and efficient methods. We established a chemically defined protocol by application of Activin A, BMP4, and Retinoic acid followed by GDNF, which steered hPSCs to the renal lineage and resulted in populations of SIX2+ /CITED1+ metanephric mesenchyme- (MM) and of HOXB7+ /GRHL2+ ureteric bud (UB)-like cells already by 6 days...
October 11, 2018: Cellular and Molecular Life Sciences: CMLS
Juan Ma, Bei-Bei Wang, Xiao-Yan Ma, Wei-Ping Deng, Li-Shu Xu, Wei-Hong Sha
AIM: To identify functional proteins involved in pancreatic-duodenal homeobox-1 (PDX1)-mediated effects on gastric carcinogenesis. METHODS: A PDX1-overexpressed model was established by transfecting gastric cancer cell line SGC7901 with pcDNA3.1(+)-PDX1 vector (SGC-PDX1). Transfection with empty pcDNA3.1 vector (SGC-pcDNA) served as control. Comparative protein profiles of the two groups were analyzed by two-dimensional electrophoresis based-proteomics (2DE gel-based proteomics)...
October 7, 2018: World Journal of Gastroenterology: WJG
M R Amans, H Haraldsson, E Kao, S Kefayati, K Meisel, R Khangura, J Leach, N D Jani, F Faraji, M Ballweber, W Smith, D Saloner
BACKGROUND AND PURPOSE: Case reports demonstrate that coiling of a sigmoid sinus diverticulum can treat pulsatile tinnitus. We hypothesized that MR imaging 4D flow and computational fluid dynamics would reveal distinct blood flow patterns in the venous outflow tract in these patients. MATERIALS AND METHODS: Patients with pulsatile tinnitus of suspected venous etiology underwent MR imaging at 3T, using venous phase contrast-enhanced MR angiography, 4D flow, and 2D phase contrast...
October 11, 2018: AJNR. American Journal of Neuroradiology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"