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Infectious spondylitis

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https://www.readbyqxmd.com/read/29881952/-what-rheumatologists-can-learn-from-ophthalmologists
#1
REVIEW
M D Becker, R Max, A Dimitriou, T Saurenmann, H-M Lorenz, A Jansen, S Lortz, J Grulich-Henn, M Weber
Intraocular inflammation with the imprecise and broad umbrella term "uveitis" is a diagnostic and therapeutic challenge in ophthalmology. Uveitis is one of the most common causes of blindness worldwide and due to the associated costs is comparable to diabetic retinopathy. Patients can be affected by uveitis at any age. Any part of the eye may be affected. The symptoms range from complete absence of symptoms, through all types of vision deterioration up to a red and even very painful eye. Uveitis can be strictly unilateral (also alternating from the left to the right eye) or bilateral with a relapsing or chronic course...
June 7, 2018: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/29752214/evaluation-of-pneumococcal-and-influenza-vaccination-coverage-in-rheumatology-patients-receiving-biological-therapy-in-a-regional-referral-hospital
#2
María Fernández-Prada, Anahy María Brandy-García, Omar Darío Rodríguez-Fonseca, Ismael Huerta-González, Federico Fernández-Noval, Carmen Martínez-Ortega
OBJECTIVE: Vaccination coverage for seasonal influenza and pneumococcus in rheumatology patients receiving biological treatment. To identify variables that predict vaccination adherence. MATERIAL AND METHOD: Descriptive cross-sectional study. The study involved rheumatology patients who initiated biological therapy between 01/01/2016 and 12/31/2016 in a regional referral hospital. Variables included sociodemographic information, diagnostic data, treating physician, referral to the vaccine unit and vaccination against pneumococcus with 13-valent pneumococcal conjugate vaccine (PCV13) and 23-valent pneumococcal polysaccharide vaccine (PPSV23), as well as seasonal influenza (2016/17)...
May 8, 2018: Reumatología Clinica
https://www.readbyqxmd.com/read/29666980/epidemiology-of-uveitis-in-a-us-population-based-study
#3
Marta Mora González, Marissé Masís Solano, Travis C Porco, Catherine E Oldenburg, Nisha R Acharya, Shan C Lin, Matilda F Chan
BACKGROUND: The purpose of this study is to assess the relationship between self-reported uveitis and purported demographic and clinical risk factors, using an American adult population extracted from the National Health and Nutrition Examination Survey (NHANES) for the years 2009 and 2010. This is a cross-sectional, population-based study using a sample of 5106 subjects between 20 and 69 years old. The main outcome for our study was the self-report of a diagnosis of uveitis. The demographic analysis included age, gender, and ethnicity...
April 17, 2018: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/29660549/perineural-spread-along-spinal-and-obturator-nerves-in-primary-vaginal-carcinoma-a-case-report
#4
Eun Jee Song, Ji Seon Park, Kyung Nam Ryu, So Young Park, Wook Jin
BACKGROUND: Perineural spread is not an uncommon feature in carcinoma of the head and neck. On the contrary, perineural spread in pelvic malignancies has been rarely reported. This is the first report on perineural spread of the obturator nerve and the lumbosacral plexus from primary vaginal cancer. CASE DESCRIPTION: A 50-year-old woman diagnosed with infectious spondylitis at an outside hospital was referred to our institution. She presented with persistent lower back pain and right anterior thigh pain...
July 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29610700/pulmonary-sarcoidosis-following-etanercept-treatment-for-ankylosing-spondylitis-a-case-report-and-review-of-the-literature
#5
A Majjad, A Bezza, A Biyi, M R El Ochi, A El Maghraoui
Antitumor necrosis factor therapies have revolutionized the treatment of some inflammatory diseases. However, the use of these agents is associated with the development of many paradoxical autoimmune diseases. Less well-recognized is the association with sarcoidosis. We report a 55-year-old female with long-standing ankylosing spondylitis who developed persistent dry cough and dyspnea while receiving etanercept therapy. High-resolution computed tomography scanning showed mediastinal lymphadenopathy and multiple nodules in both lung fields developed two months after the administration of etanercept...
2018: Case Reports in Rheumatology
https://www.readbyqxmd.com/read/29354239/comparative-analysis-of-spontaneous-infectious-spondylitis-pyogenic-versus-tuberculous
#6
Yangwon Lee, Bum-Joon Kim, Se-Hoon Kim, Seung-Hwan Lee, Won-Hyung Kim, Sung-Won Jin
Objective: Spondylitis is often chemotherapy resistant and requires long-term treatment. Without adequate chemotherapy, the outcome can be fatal or result in severe neurologic damage. Therefore, differentiating the etiology of spondylitis is very important, particularly in spontaneous cases. As the prevalence of tuberculosis in Korea has decreased in recent years, updated clinical research about spondylitis is warranted. Methods: From April 2010 to March 2016, data from spondylitis patients were collected retrospectively...
January 2018: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29299700/emergent-spinal-mri-in-ivdu-patients-presenting-with-back-pain-do-we-need-an-mri-in-every-case
#7
Charles G Colip, Mina Lotfi, Karen Buch, Nagaraj Holalkere, Bindu N Setty
PURPOSE: Spinal MRI is the exam of choice for the workup of patients with suspected spinal infection. In this retrospective study, we assess the value of obtaining contrast-enhanced spinal MRI for patients presenting to the emergency department (ED) with acute back pain and a history of intravenous drug use (IVDU). METHODS: A retrospective IRB-approved, HIPAA compliant review of the imaging findings, reports and electronic charts of 167 consecutive IV drug-using patients (M/F = 96:71, mean age = 40 years) that presented to the ED with acute back pain over a 55-month period and underwent contrast-enhanced spinal MRI within 24 h...
June 2018: Emergency Radiology
https://www.readbyqxmd.com/read/28979855/single-stage-anterior-debridement-and-reconstruction-with-tantalum-mesh-cage-for-complicated-infectious-spondylitis
#8
Shih-Chieh Yang, Hung-Shu Chen, Yu-Hsien Kao, Yuan-Kun Tu
AIM: To evaluate the clinical and radiographic results of patients with complicated infectious spondylitis treated with single-stage anterior debridement and reconstruction using tantalum mesh cage (TaMC) followed by immediate instrumentation. METHODS: Single-stage radical debridement and subsequent reconstruction with TaMC instead of autograft or allograft were performed to treat 20 patients with spinal deformity or instability due to complicated infectious spondylitis...
September 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28976894/spontaneous-spondylodiscitis-epidemiology-clinical-features-diagnosis-and-treatment
#9
REVIEW
Aneta S Petkova, Christo B Zhelyazkov, Borislav D Kitov
Spontaneous spondylodiscitis is a rare but serious infectious disease which is a combination of an inflammatory process, involving one or more adjacent vertebral bodies (spondylitis), the intervertebral discs (discitis) and finally - the neighboring neural structures. In most cases the condition is due to a hematogenous infection and can affect all regions of the spinal cord, but it is usually localized in the lumbar area. The most common clinical symptom is a pronounced, constant and increasing nocturnal paravertebral pain, while consequently different degrees of residual neurological symptoms from nerve roots and/or spinal cord may appear...
September 1, 2017: Folia Medica
https://www.readbyqxmd.com/read/28697197/increased-and-normalized-uptake-of-18-f-fdg-in-a-case-of-bone-periprosthetic-infection-treated-by-antibiotics
#10
Valentina Lavelli, Cristina Ferrari, Artor Niccoli Asabella, Corinna Altini, Francesco Saverio Vella, Giuseppe Rubini
We report the case of a 69 years old man with left hip prosthesis, who presented clinical, biochemical and imaging signs of periprosthetic infection treated with linezolid, an antibacterial agent of the oxazolidinone class. Two weeks after this treatment, a fluorine-18-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) scan showed increased uptake in the skeleton and also increased uptake in several focal areas in the spine and near the prosthesis and the surgical wound on the left gluteus medius...
May 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28612240/clinical-characteristics-of-peripheral-spondyloarthritis-without-psoriasis-inflammatory-enteropathy-or-preceding-infection-from-a-single-rheumatology-clinic-in-northern-india
#11
Anand Narayan Malaviya, Neha Agrawal, Nilesh Sahebrao Patil
The objective of this study was to characterise the peripheral arthritis of spondyloarthritis (pSpA) excluding psoriatic-, inflammatory enteropathy-related, post-infectious reactive-SpA and arthritis associated with axial SpA/ankylosing spondylitis (axSpA/AS). Patients presenting with the clinical features of the broad spectrum of SpA were screened for the presence of peripheral arthritis using the Assessment of SpondyloArthritis International Society (ASAS) criteria. The other conditions that could cause pSpA, e...
November 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28583781/-macrophage-activation-syndrome-and-kawasaki-disease-four-new-cases
#12
B Dumont, P Jeannoel, L Trapes, E Rolland, C Gay, J-L Stephan
Macrophage activation syndrome (MAS) is a rarely reported complication of Kawasaki disease (KD). It must be sought during KD with unusual clinical signs, such as enlargement of the liver or spleen, cytopenia (including thrombocytopenia), and elevated serum triglycerides. Here, we report four cases from a single center. The first is the description of a case of KD occurring in an 11-month-old child 15 days after the occurrence of infectious spondylitis. For the second, acute myocarditis heralded KD in a 5-year-old child...
July 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28299317/application-of-intraoperative-ct-guided-navigation-in-simultaneous-minimally-invasive-anterior-and-posterior-surgery-for-infectious-spondylitis
#13
Meng-Huang Wu, Navneet Kumar Dubey, Ching-Yu Lee, Yen-Yao Li, Chin-Chang Cheng, Chung-Sheng Shi, Tsung-Jen Huang
This study was aimed at evaluating the safety and efficacy of using intraoperative computed tomography- (iCT-) guided navigation in simultaneous minimally invasive anterior and posterior surgery for infectious spondylitis. Nine patients with infectious spondylitis were enrolled in this study. The average operative time was 327.6 min (range, 210-490) and intraoperative blood loss was 407 cc (range, 50-1,200). The average duration of hospital stay was 48.9 days (range, 11-76). Out of a total of 54 pedicle screws employed, 53 screws (98...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28298562/deaths-associated-with-ankylosing-spondylitis-in-france-from-1969-to-2009
#14
Clément Prati, Marc Puyraveau, Xavier Guillot, Franck Verhoeven, Daniel Wendling
OBJECTIVE: To describe deaths for which ankylosing spondylitis (AS) was on death certificates in France. METHODS: Death certificates in which AS was indicated were evaluated. Standard mortality ratio (SMR) was assessed. RESULTS: AS appeared in 2940 death certificates. The mortality rate of AS seemed stable. The most frequent initial causes were diseases of the circulatory system [28.3% in the International Classification of Diseases, 10th ed (ICD-10)]...
May 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28264814/risk-of-serious-infections-associated-with-use-of-immunosuppressive-agents-in-pregnant-women-with-autoimmune-inflammatory-conditions-cohort-study
#15
Rishi J Desai, Brian T Bateman, Krista F Huybrechts, Elisabetta Patorno, Sonia Hernandez-Diaz, Yoonyoung Park, Sara Z Dejene, Jacqueline Cohen, Helen Mogun, Seoyoung C Kim
Objective To compare the risk of serious infections associated with use of systemic steroids, non-biologic agents, or tumor necrosis factor α (TNF) inhibitors in pregnancy.Design Observational cohort study.Setting Public (Medicaid, 2001-10) or private (Optum Clinformatics, 2004-15) health insurance programs in the US.Participants 4961 pregnant women treated with immunosuppressive drugs for rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis, psoriatic arthritis, or inflammatory bowel disease...
March 6, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28253945/-pyogenic-spinal-infections-in-adults-a-5-year-experience-from-a-tertiary-care-centre
#16
O Džupová, R Cihlářová
PURPOSE OF THE STUDY To describe epidemiological and clinical features of pyogenic spinal infections in patients treated at the Department of Infectious, Parasitic and Tropical Diseases of the Hospital Na Bulovce in 2010-2014, and to analyse a predictive significance of selected variables. MATERIAL AND METHODS A single-centre retrospective cohort study carried out from 1.1.2010 to 31.12.2014 enrolled adult patients with septic spondylitis, discitis and facet joint infections. Recorded parameters included: demographics, chronic comorbidities, time to diagnosis, radiological work-up, anatomical level of spinal infection, source of infection, etiological agent, complications, treatment and outcomes...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28244282/descriptive-epidemiology-of-patients-undergoing-total-hip-arthroplasty-in-korea-with-focus-on-incidence-of-femoroacetabular-impingement-single-center-study
#17
Woo Yong Lee, Deuk Soo Hwang, Chang Kyun Noh
We analyzed the causes leading to total hip arthroplasty (THA), aimed to clarify the incidence of femoroacetabular impingement (FAI) among the causes, and compared the incidence in Korea with those in other countries. From January 2000 to December 2014, 1,206 hips of 818 patients who underwent primary THA at our institute were reviewed retrospectively in terms of radiographs and electronic charts. The radiographs and radiographic parameters were reviewed and measured by 2 of the authors, who are orthopedic surgeons...
April 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28149665/seronegative-brucellosis-of-the-spine-a-case-of-psoas-abscess-secondary-to-brucellar-spondylitis
#18
Gülnur Taşcı Bozbaş, Ayşe İyiyapıcı Ünübol, Gülcan Gürer
Brucellosis is an infectious disease that affects many organ systems. Osteoarticular involvement, especially spondylitis, is the most common complication of brucellosis, but psoas abscess is very rare. Serological tests at diagnosis of the disease are very valuable and most widely used. Herein, we report a case of psoas abscess secondary to brucellar spondylitis. In this case, interestingly, the serological test results were negative, and the diagnosis could be made by abscess culture. In patients, particularly those who live in areas endemic for brucellosis, as in our case, it should be kept in mind that a negative serological test result should not exclude the diagnosis of brucellosis...
December 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/27956325/profile-of-patients-with-uveitis-referred-to-a-multidisciplinary-unit-in-northern-spain
#19
COMPARATIVE STUDY
P Fanlo, H Heras, D Pérez, G Tiberio, G Espinosa, A Adan
OBJECTIVE: To describe the main characteristics of a cohort of patients with uveitis referred to a multidisciplinary unit in northern Spain. MATERIAL AND METHODS: Retrospective analysis of clinical records of patients evaluated in the Multidisciplinary Unit of the Navarra Hospital Complex from the period January 2010 until March 2015. An analysis was performed on the demographic characteristics, origin, types of uveitis, laterality, and aetiology. The present series was also compared with 2 previous series from Castilla y León and Barcelona...
May 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27924643/risk-of-infections-using-anti-tnf-agents-in-rheumatoid-arthritis-psoriatic-arthritis-and-ankylosing-spondylitis-a-systematic-review-and-meta-analysis
#20
REVIEW
Silvia Minozzi, Stefanos Bonovas, Theodore Lytras, Valentina Pecoraro, Marien González-Lorenzo, Anan Judina Bastiampillai, Eugenia Maria Gabrielli, Andrea Carlo Lonati, Lorenzo Moja, Michela Cinquini, Valentina Marino, Andrea Matucci, Giuseppe Maria Milano, Giuliano Tocci, Raffaele Scarpa, Delia Goletti, Fabrizio Cantini
Five anti-tumor necrosis factor (anti-TNF) agents have received regulatory approval for use in rheumatology: adalimumab, golimumab, infliximab, certolizumab, and etanercept. Apart from their well-documented therapeutic value, it is still uncertain to what extent they are associated with an increased risk of infectious adverse events. Areas covered: We conducted a systematic review and meta-analysis of published randomized studies to determine the effect of anti-TNF drugs on the occurrence of infectious adverse events (serious infections; tuberculosis; opportunistic infections; any infection)...
December 2016: Expert Opinion on Drug Safety
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