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Aging Meta-analysis

Han Zhang, Chong-Yaw Wee, Joann S Poh, Qiang Wang, Lynette P Shek, Yap-Seng Chong, Marielle V Fortier, Michael J Meaney, Birit F P Broekman, Anqi Qiu
Early numeracy provides the foundation of acquiring mathematical skills that is essential for future academic success. This study examined numerical functional networks in relation to counting and number relational skills in preschoolers at 4 and 6 years of age. The counting and number relational skills were assessed using school readiness test (SRT). Resting-state fMRI (rs-fMRI) was acquired in 123 4-year-olds and 146 6-year-olds. Among them, 61 were scanned twice over the course of 2 years. Meta-analysis on existing task-based numeracy fMRI studies identified the left parietal-dominant network for both counting and number relational skills and the right parietal-dominant network only for number relational skills in adults...
October 12, 2018: Brain Structure & Function
Le Peng, Korbinian Weigl, Daniel Boakye, Hermann Brenner
OBJECTIVES: A systematic review and meta-analysis was performed to summarize the available evidence on risk scores for predicting advanced colorectal neoplasia (advanced adenomas and cancer) in average-risk and asymptomatic populations undergoing screening colonoscopy. METHODS: PubMed, EMBASE, and Web of Science databases were searched up to 28 March 2018. Studies that developed or validated a risk score to predict the risk of advanced colorectal neoplasia were included...
October 12, 2018: American Journal of Gastroenterology
Marta Krasuska, Thomas L Webb
OBJECTIVE: The present review sought to evaluate whether - and to what extent - targeting owners' behaviour is an effective way to reduce the problem of overweight and obesity among companion dogs. METHODS: A systematic search of electronic databases identified 14 studies that evaluated the effect of an intervention targeting owners' behaviour on (i) the owner's behaviour or (ii) the weight, (iii) body fat, or (iv) body condition of the dog. We coded aspects of the study design (e...
November 1, 2018: Preventive Veterinary Medicine
Ke Ma, Yangwei Fan, Yuan Hu
BACKGROUND: In the past 2 decades, metastasis-associated gene 1 (MTA1) has attracted attention for its close association with cancer progression and its roles in chromatin remodeling processes, making it a central gene in cancer. The present meta-analysis was performed to assess MTA1 expression in solid tumors. MATERIALS AND METHODS: This analysis identified studies that evaluated the relationship between MTA1 expression and clinical characteristics or prognosis of patients with solid tumors via the PubMed, Cochrane Library, and Embase electronic databases...
October 2018: Medicine (Baltimore)
Nirma Khatri Vadlamudi, Anna Chen, Fawziah Marra
BACKGROUND: A notable reduction of pneumococcal disease burden among adults was observed after introduction of 7 valent- pneumococcal conjugate vaccine in childhood immunization programs. In 2010, 13 valent-pneumococcal conjugate vaccine (PCV13) replaced PCV7 in many jurisdictions; a comparative assessment of PCV13's impact has not yet been performed. OBJECTIVE: To summarize available data and assess the change in the incidence of invasive pneumococcal disease (IPD) in adults after the introduction of PCV13 in childhood immunization programs...
October 12, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Jennifer A Hutcheon, Susan Moskosky, Cande V Ananth, Olga Basso, Peter A Briss, Cynthia D Ferré, Brittni N Frederiksen, Sam Harper, Sonia Hernández-Díaz, Ashley H Hirai, Russell S Kirby, Mark A Klebanoff, Laura Lindberg, Sunni L Mumford, Heidi D Nelson, Robert W Platt, Lauren M Rossen, Alison M Stuebe, Marie E Thoma, Catherine J Vladutiu, Katherine A Ahrens
BACKGROUND: Meta-analyses of observational studies have shown that women with a shorter interpregnancy interval (the time from delivery to start of a subsequent pregnancy) are more likely to experience adverse pregnancy outcomes, such as preterm delivery or small for gestational age birth, than women who space their births further apart. However, the studies used to inform these estimates have methodological shortcomings. METHODS: In this commentary, we summarise the discussions of an expert workgroup describing good practices for the design, analysis, and interpretation of observational studies of interpregnancy interval and adverse perinatal health outcomes...
October 12, 2018: Paediatric and Perinatal Epidemiology
Konstantinos Vazouras, Romain Basmaci, Julia Bielicki, Laura Folgori, Theoklis Zaoutis, Mike Sharland, Yingfen Hsia
PURPOSE: Urinary tract infections (UTIs) are common bacterial infections among children. OBJECTIVE: To systematically review the antimicrobials used for febrile UTIs in paediatric clinical trials and meta-analyse the observed cure rates and reasons for treatment failure. MATERIALS AND METHODS: We searched Medline, Embase and Cochrane central databases between January 1, 1990, and November 24, 2016, combining MeSH and free-text terms for: "urinary tract infections", AND "therapeutics", AND "clinical trials" in children (age range 0-18 years)...
October 11, 2018: Drugs
Stephanie Q Ko, Linda R Valsdottir, Jordan B Strom, Yu-Chen Cheng, Atsushi Hirayama, Po-Hong Liu, Naoki Yanagisawa, Hsuan Yen, Changyu Shen, Robert W Yeh
The duration and type of dual antiplatelet therapy (DAPT) prescribed to patients after percutaneous coronary intervention (PCI) involves carefully balancing reduced ischemia and increased bleeding risk for individual patients. Whereas multiple bleeding risk scores exist, the performance of these models to predict long-term bleeding in the setting of DAPT across different settings and populations is unclear. Therefore, we performed a systematic review and meta-analysis to compare the performance of current bleeding risk prediction scores for predicting major long-term bleeding events in patients on DAPT post-PCI...
September 8, 2018: American Journal of Cardiology
Thomas Drago, Patrick W O'Regan, Ivan Welaratne, Shane Rooney, Aoife O'Callaghan, Marissa Malkit, Elena Roman, Kirk J Levins, Lauren Alexander, Denis Barry, Erik O'Hanlon, Veronica O'Keane, Darren William Roddy
BACKGROUND: Magnetic resonance spectroscopy (MRS) is a non-invasive analytical technique that investigates the presence and concentrations of brain metabolites. In the context of major depressive disorder (MDD), MRS has revealed regional biochemical changes in GABA, glutamate, and choline across different brain compartments. Technical and methodological advances in MRS data acquisition, in particular proton-based 1 H-MRS, have resulted in a significant increase in the incidence of reports utilizing the technique for psychiatric disorder research and diagnosis...
October 12, 2018: Systematic Reviews
Shimona Prosad, Tivani P Mashamba-Thompson, Elizabeth Ojewole
BACKGROUND: According to the United Nations Trends in Contraceptive Use 2015 report, at least one in ten married or in-union women in most regions of the world has an unmet need for family planning. Family Planning 2020 reports an estimate of almost 134 million married or in-union women of reproductive age who have an unmet need for modern methods of contraception in 2016 in participating countries. Family planning has therefore been highlighted as a global unmet need. Initiatives such as Family Planning 2020 aim to promote contraceptive use through Implanon® contraceptive implant...
October 12, 2018: Systematic Reviews
María Isabel Gómez-Núñez, María Soledad Torregrosa, Cándido J Inglés, Nelly G Lagos San Martín, Ricardo Sanmartín, María Vicent, José Manuel García-Fernández
The purpose of this study is to adapt the Trait Meta-Mood Scale-24 (TMMS-24; Fernández-Berrocal, Extremera, & Ramos, 2004 , Spanish short version of the TMMS, Salovey, Mayer, Goldman, Turvey, & Palfai, 1995 ) to the Chilean adolescent population (13-17 years), analyzing the psychometric properties of the instrument through confirmatory factor analyses, factor invariance analysis, and latent mean differences. For this purpose, a sample of 3,255 secondary and high school students, between 12 and 18 years old (M = 15...
October 11, 2018: Journal of Personality Assessment
Marina Antillon, Neil J Saad, Stephen Baker, Andrew J Pollard, Virginia E Pitzer
Background: Blood culture is the standard diagnostic method for typhoid and paratyphoid (enteric) fever in surveillance studies and clinical trials, but sensitivity is widely acknowledged to be suboptimal. We conducted a systematic review and meta-analysis to examine sources of heterogeneity across studies and quantified the effect of blood volume. Methods: We searched the literature to identify all studies that performed blood culture alongside bone marrow culture (a gold standard) to detect cases of enteric fever...
October 11, 2018: Journal of Infectious Diseases
Qing Yu Zheng, Kim T Huynh, Wendy J van Zuylen, Maria E Craig, William D Rawlinson
Maternofetal transmission of cytomegalovirus (CMV) is the most common infectious cause of congenital malformation in developed countries. Maternal infection often results from close contact with infected children, and this may occur in day care centres (DCCs). A systematic review of observational studies was conducted to examine the prevalence of CMV infection among children attending DCCs. Meta-analysis using the random effect model was performed for studies including controls. Sources included PubMed, EMBASE (until August 2018), and references from identified publications...
October 10, 2018: Reviews in Medical Virology
Spyridon N Papageorgiou, Theodore Eliades, Christoph H F Hämmerle
OBJECTIVES: The aim of this systematic review was to assess clinical evidence on adverse effects of osseointegrated implants placed among natural teeth of a residual dentition. METHODS: Seven databases were searched without restrictions up to January 2018 for clinical studies on implant infraposition (IIP) or proximal contact point (PCP) loss to the adjacent teeth. After duplicate selection, data extraction, and risk of bias assessment according to the Cochrane guidelines, random-effects meta-analyses of odds ratios (OR) or mean differences (MD) and their 95% confidence intervals (CI) were performed, followed by meta-regression and sensitivity analyses...
October 2018: Clinical Oral Implants Research
Morris Gordon, Elena Biagioli, Miriam Sorrenti, Carla Lingua, Lorenzo Moja, Shel Sc Banks, Simone Ceratto, Francesco Savino
BACKGROUND: Infantile colic is typically defined as full-force crying for at least three hours per day, on at least three days per week, for at least three weeks. This condition appears to be more frequent in the first six weeks of life (prevalence range of 17% to 25%), depending on the specific location reported and definitions used, and it usually resolves by three months of age. The aetiopathogenesis of infantile colic is unclear but most likely multifactorial. A number of psychological, behavioural and biological components (food hypersensitivity, allergy or both; gut microflora and dysmotility) are thought to contribute to its manifestation...
October 10, 2018: Cochrane Database of Systematic Reviews
Louis McCusky Gendron, Andre Nyberg, Didier Saey, François Maltais, Yves Lacasse
BACKGROUND: Active mind-body movement therapies (AMBMTs), including but not limited to yoga, tai chi, and qigong, have been applied as exercise modalities for people with chronic obstructive pulmonary disease (COPD). AMBMT strategies have been found to be more effective than usual care; however, whether AMBMT is inferior, equivalent, or superior to pulmonary rehabilitation (PR) in people with COPD remains to be determined. OBJECTIVES: To assess the effects of AMBMTs compared with, or in addition to, PR in the management of COPD...
October 10, 2018: Cochrane Database of Systematic Reviews
T Vilaca, J Walsh, R Eastell
To clarify if the peripheral microarchitectural abnormalities described in diabetics have clinical consequences, we evaluated the risk of wrist and ankle fractures. The meta-analysis resulted in an increase in the risk of ankle fractures and a decrease in wrist fractures risk, suggesting that microarchitecture may not be the major fracture determinant. INTRODUCTION: There is evidence for an increase in the risk of hip fractures in diabetes (both in type 1 and 2), but the risk is not established for other skeletal sites...
October 10, 2018: Osteoporosis International
Barbara Joschtel, Sjaan R Gomersall, Sean Tweedy, Helen Petsky, Anne B Chang, Stewart G Trost
Introduction: Chronic disease in children is increasing, including the prevalence of chronic respiratory diseases such as asthma, cystic fibrosis (CF), bronchiectasis and bronchopulmonary dysplasia (BPD). The aim of this systematic review and meta-analysis was to evaluate the effects of exercise training on health outcomes in children with chronic respiratory disease. Method: Five databases were searched for randomised controlled trials investigating the effects of exercise training on children with chronic respiratory disease...
2018: BMJ Open Sport & Exercise Medicine
Tanya J Major, Ruth K Topless, Nicola Dalbeth, Tony R Merriman
OBJECTIVE: To systematically test dietary components for association with serum urate levels and to evaluate the relative contributions of estimates of diet pattern and inherited genetic variants to population variance in serum urate levels. DESIGN: Meta-analysis of cross sectional data from the United States. DATA SOURCES: Five cohort studies. REVIEW METHODS: 16 760 individuals of European ancestry (8414 men and 8346 women) from the US were included in analyses...
October 10, 2018: BMJ: British Medical Journal
Ester di Giacomo, Micheal Krausz, Fabrizia Colmegna, Flora Aspesi, Massimo Clerici
Importance: Suicide is the second-leading cause of death among adolescents. Sexual minority individuals are at a higher risk of suicide and attempted suicide, but a precise and systematic evaluation of this risk among sexual minority youths has not been documented to our knowledge. Objective: To examine the risk of attempted suicide among sexual minority adolescents, differentiating for each sexual minority group. Data Sources: Electronic databases (PubMed, Embase, and PsycINFO) were searched for articles published through April 30, 2017, with the following search terms: heterosexual, homosexual, bisexual, transgender, adolescents, teens, and attempted suicide...
October 8, 2018: JAMA Pediatrics
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