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https://www.readbyqxmd.com/read/29338075/lkb1-ampk-mediated-regulation-by-gentiopicroside-ameliorates-p2x7r-dependent-alcoholic-hepatosteatosis
#1
Xia Li, Yu Zhang, Quan Jin, Kai-Li Xia, Min Jiang, Ben-Wen Cui, Yan-Ling Wu, Shun-Zong Song, Li-Hua Lian, Ji-Xing Nan
BACKGROUND AND PURPOSE: Regulating P2x7R-NLRP3 inflammasome activation might be a potential therapeutic strategy to treat alcoholic hepatosteatosis. We investigated whether this process would be modulated by gentiopicroside (GPS), which is the main active secoiridoid glycoside from Gentiana manshurica Kitagawa. EXPERIMENTAL APPROACH: In vivo models of acute and chronic alcoholic hepatosteatosis were established by intragastrically administrated ethanol or using chronic plus binge ethanol feeding of Lieber-DeCarli liquid diet to male C57BL/6 mice...
January 16, 2018: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29326391/zoonotic-bacteria-and-parasites-found-in-raw-meat-based-diets-for-cats-and-dogs
#2
Freek P J van Bree, Gertie C A M Bokken, Robin Mineur, Frits Franssen, Marieke Opsteegh, Joke W B van der Giessen, Len J A Lipman, Paul A M Overgaauw
Feeding raw meat-based diets (RMBDs) to companion animals has become increasingly popular. Since these diets may be contaminated with bacteria and parasites, they may pose a risk to both animal and human health. The purpose of this study was to test for the presence of zoonotic bacterial and parasitic pathogens in Dutch commercial RMBDs. We analysed 35 commercial frozen RMBDs from eight different brands. Escherichia coli serotype O157:H7 was isolated from eight products (23 per cent) and extended-spectrum beta-lactamases-producing E coli was found in 28 products (80 per cent)...
January 13, 2018: Veterinary Record
https://www.readbyqxmd.com/read/29326390/the-trend-of-raw-meat-based-diets-risks-to-people-and-animals
#3
Barbara Hinney
No abstract text is available yet for this article.
January 13, 2018: Veterinary Record
https://www.readbyqxmd.com/read/29315588/the-health-nutrition-dimension-a-methodological-approach-to-asses-the-nutritional-sustainability-of-the-typical-agro-food-products-and-the-mediterranean-diet
#4
Elena Azzini, Giuseppe Maiani, Aida Turrini, Federica Intorre, Gabriella Lo Feudo, Roberto Capone, Francesco Bottalico, Hamid El Bilali, Angela Polito
BACKGROUND: The aim of this paper is to work out a methodological approach for the evaluation nutritional sustainability of typical agro-food products, representing the Mediterranean eating habits and included in the Mediterranean food pyramid. RESULTS: For each group of foods, were identified different suitable and easily measurable indicators. Two macro-indicators were used to assess the nutritional sustainability of each product. The first macro-indicator called "business distinctiveness" takes into account the application of different regulations and standards regarding quality, safety and traceability as well as the origin of raw materials...
January 9, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29285134/sicyos-angulatus-ameliorates-atherosclerosis-through-downregulation-of-aortic-inflammatory-responses-in-apolipoprotein-e-deficient-mice
#5
Yong-Hoon Kim, Jung-Ran Noh, Jung Hwan Hwang, Kyoung-Shim Kim, Dong-Hee Choi, Jin-Pyo An, Won-Keun Oh, Chul-Ho Lee
Sicyos angulatus (SA), a summer annual vine originating from Northeastern USA, is a widely distributed noxious invasive plant. However, the clinical application of SA has not been investigated previously. The purpose of present study was to determine the effects of SA on atherosclerosis and its underlying mechanism. Atherosclerosis was induced by feeding apolipoprotein E-deficient (apoE-/-) mice with an atherogenic diet for 8 weeks. SA was administered daily by oral gavage during induction of atherosclerosis...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29282153/under-control-how-a-dietary-additive-can-restore-the-gut-microbiome-and-proteomic-profile-and-improve-disease-resilience-in-a-marine-teleostean-fish-fed-vegetable-diets
#6
María Carla Piazzon, Josep Alvar Calduch-Giner, Belén Fouz, Itziar Estensoro, Paula Simó-Mirabet, Mónica Puyalto, Vasileios Karalazos, Oswaldo Palenzuela, Ariadna Sitjà-Bobadilla, Jaume Pérez-Sánchez
BACKGROUND: The constant increase of aquaculture production and wealthy seafood consumption has forced the industry to explore alternative and more sustainable raw aquafeed materials, and plant ingredients have been used to replace marine feedstuffs in many farmed fish. The objective of the present study was to assess whether plant-based diets can induce changes in the intestinal mucus proteome, gut autochthonous microbiota and disease susceptibility of fish, and whether these changes could be reversed by the addition of sodium butyrate to the diets...
December 28, 2017: Microbiome
https://www.readbyqxmd.com/read/29258552/effects-of-stevia-on-synaptic-plasticity-and-nadph-oxidase-level-of-cns-in-conditions-of-metabolic-disorders-caused-by-fructose
#7
V A Chavushyan, K V Simonyan, R M Simonyan, A S Isoyan, G M Simonyan, M A Babakhanyan, L E Hovhannisyian, Kh H Nahapetyan, L G Avetisyan, M A Simonyan
BACKGROUND: Excess dietary fructose intake associated with metabolic syndrome and insulin resistance and increased risk of developing type 2 diabetes. Previous animal studies have reported that diabetic animals have significantly impaired behavioural and cognitive functions, pathological synaptic function and impaired expression of glutamate receptors. Correction of the antioxidant status of laboratory rodents largely prevents the development of fructose-induced plurimetabolic changes in the nervous system...
December 19, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29248026/prevalence-of-food-neophobia-in-pre-school-children-from-southern-poland-and-its-association-with-eating-habits-dietary-intake-and-anthropometric-parameters-a-cross-sectional-study
#8
Agnieszka Kozioł-Kozakowska, Beata Piórecka, Małgorzata Schlegel-Zawadzka
OBJECTIVES: The present study aimed to assess the prevalence of food neophobia in pre-school children and its association with eating habits, dietary intake and anthropometric parameters. DESIGN: Cross-sectional survey performed in 2012-2013. The Child Food Neophobia Scale (CFNS) adapted by Wardle, Carnell and Cooke was used to assess the level of food neophobia. Dietary intake was measured using an FFQ and dietary records from three days. Anthropometric measurements were taken to determine children's nutritional status and BMI was computed based on Polish growth charts...
December 18, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29241580/in-vitro-fermented-raw-and-roasted-walnuts-induce-expression-of-cat-and-gstt2-genes-growth-inhibition-and-apoptosis-in-lt97-colon-adenoma-cells
#9
W Schlörmann, J Lamberty, D Ludwig, S Lorkowski, M Glei
Walnuts are rich in bioactive compounds such as polyunsaturated fatty acids, polyphenols, and dietary fiber. Therefore, the consumption of walnuts can contribute to a healthy diet and may reduce the risk for colon cancer. Heat treatment like roasting may change the chemical composition of walnuts and therefore their chemopreventive properties. Therefore, the hypothesis of the present study is that different roasting conditions (RCs) alter the chemopreventive effects of walnuts. Thus, the aim of the present study was to investigate whether different RCs (RC1=139...
November 2017: Nutrition Research
https://www.readbyqxmd.com/read/29224876/effect-of-different-forage-types-on-the-volatile-and-sensory-properties-of-bovine-milk
#10
Hope Faulkner, Tom F O'Callaghan, Stephen McAuliffe, Deirdre Hennessy, Catherine Stanton, Maurice G O'Sullivan, Joseph P Kerry, Kieran N Kilcawley
The effect of 3 diets (grass, grass/clover, and total mixed ration) on the volatile and sensory properties of bovine milk was assessed over an entire lactation season. Little evidence was found of direct transfer of terpenes into raw milk from the different diets, and it is likely that the monocultures of ryegrass used with and without white clover were factors as these contained very few terpenes. Evidence of direct transfer of nonterpene volatiles from forage to the subsequent raw milks was probable; however, differences in the protein carbohydrate availability and digestion in the rumen appeared to have a greater contribution to volatile profiles...
December 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29221725/protective-effects-of-polyphenol-rich-infusions-from-carob-ceratonia-siliqua-leaves-and-cladodes-of-opuntia-ficus-indica-against-inflammation-associated-with-diet-induced-obesity-and-dss-induced-colitis-in-swiss-mice
#11
Ikram Aboura, Abdelhafid Nani, Meriem Belarbi, Babar Murtaza, Aurélie Fluckiger, Adélie Dumont, Chahid Benammar, Moufida Saidani Tounsi, François Ghiringhelli, Mickaël Rialland, Naim Akhtar Khan, Aziz Hichami
In the present study, we have investigated the effects of polyphenol-rich infusions from carob leaves and OFI-cladodes on inflammation associated with obesity and dextran sulfate sodium (DSS)-induced ulcerative colitis in Swiss mice. In vitro studies revealed that aqueous extracts of carob leaves and OFI-cladodes exhibited anti-inflammatory properties marked by the inhibition of IL-6, TNF-α and nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells concomitant with NF-κβ nucleus translocation inhibition...
December 6, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29207478/phenolic-content-and-antioxidant-activity-in-raw-and-denatured-aqueous-extracts-from-sprouts-and-wheatgrass-of-einkorn-and-emmer-obtained-under-salinity
#12
Beatrice Falcinelli, Paolo Benincasa, Isabella Calzuola, Lilia Gigliarelli, Stanley Lutts, Valeria Marsili
Total phenolic content (TPC), reducing power (RP), superoxide radical scavenging (RS), and thiobarbituric acid reactive substances (TBARS) production inhibition were measured in raw and denatured aqueous extracts from sprouts and wheatgrass of einkorn and emmer obtained at increasing salinity. Grains were incubated and kept at 0, 25, 50, and 100 mM NaCl until either sprout or wheatgrass stage. Additionally, a recovery treatment was included, in which sprouts obtained at 100 mM NaCl were then transferred at 0 mM NaCl until wheatgrass stage...
December 2, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29201150/differences-in-the-gut-microbiota-of-dogs-canis-lupus-familiaris-fed-a-natural-diet-or-a-commercial-feed-revealed-by-the-illumina-miseq-platform
#13
Junhyung Kim, Jae-Uk An, Woohyun Kim, Soomin Lee, Seongbeom Cho
Background: Recent advances in next-generation sequencing technologies have enabled comprehensive analysis of the gut microbiota, which is closely linked to the health of the host. Consequently, several studies have explored the factors affecting gut microbiota composition. In recent years, increasing number of dog owners are feeding their pets a natural diet i.e., one consisting of bones, raw meat (such as chicken and beef), and vegetables, instead of commercial feed. However, the effect of these diets on the microbiota of dogs (Canis lupus familiaris) is unclear...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/29197280/occurrence-of-cyclic-imines-in-european-commercial-seafood-and-consumers-risk-assessment
#14
Maria Rambla-Alegre, Christopher O Miles, Pablo de la Iglesia, Margarita Fernandez-Tejedor, Silke Jacobs, Isabelle Sioen, Wim Verbeke, Ingunn A Samdal, Morten Sandvik, Vera Barbosa, Alice Tediosi, Eneko Madorran, Kit Granby, Michiel Kotterman, Tanja Calis, Jorge Diogene
Cyclic imines constitute a quite recently discovered group of marine biotoxins that act on neural receptors and that bioaccumulate in seafood. They are grouped together due to the imino group functioning as their common pharmacore, responsible for acute neurotoxicity in mice. Cyclic imines (CIs) have not been linked yet to human poisoning and are not regulated in the European Union (EU), although the European Food Safety Authority (EFSA) requires more data to perform conclusive risk assessment for consumers...
November 29, 2017: Environmental Research
https://www.readbyqxmd.com/read/29194641/chemometric-analysis-of-minerals-in-gluten-free-products
#15
Anna Gliszczyńska-Świgło, Inga Klimczak, Iga Rybicka
BACKGROUND: Numerous studies indicate mineral deficiencies in people on a gluten-free (GF) diet. These deficiencies may indicate that GF products are less valuable source of minerals than gluten-containing products. In the study, the nutritional quality of fifty GF products is discussed taking into account the nutritional requirements for minerals expressed as % Recommended Daily Allowance (%RDA) or % Adequate Intake (%AI) for a model celiac patient. Analysed elements were: calcium, potassium, magnesium, sodium, copper, iron, manganese, and zinc...
November 30, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29190664/a-systematic-review-of-zoonotic-enteric-parasitic-diseases-among-nomadic-and-pastoral-people
#16
Amber N Barnes, Anu Davaasuren, Uyanga Baasandagva, Gregory C Gray
INTRODUCTION: Zoonotic enteric parasites are ubiquitous and remain a public health threat to humans due to our close relationship with domestic animals and wildlife, inadequate water, sanitation, and hygiene practices and diet. While most communities are now sedentary, nomadic and pastoral populations still exist and experience unique exposure risks for acquiring zoonotic enteric parasites. Through this systematic review we sought to summarize published research regarding pathogens present in nomadic populations and to identify the risk factors for their infection...
2017: PloS One
https://www.readbyqxmd.com/read/29189903/comparison-of-food-consumption-and-nutrient-intake-assessed-with-three-dietary-assessment-methods-results-of-the-german-national-nutrition-survey-ii
#17
Andrea Straßburg, Marianne Eisinger-Watzl, Carolin Krems, Alexander Roth, Ingrid Hoffmann
PURPOSE: Comparison of food consumption, nutrient intake and underreporting of diet history interviews, 24-h recalls and weighed food records to gain further insight into specific strength and limitations of each method and to support the choice of the adequate dietary assessment method. METHODS: For 677 participants (14-80 years) of the German National Nutrition Survey II confidence intervals for food consumption and nutrient intake were calculated on basis of bootstrapping samples, Cohen's d for the relevance of differences, and intraclass correlation coefficients for the degree of agreement of dietary assessment methods...
November 30, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/29189183/ige-sensitization-to-anisakis-simplex-and-diet-recommendation-in-a-polycentric-study
#18
Rosalba Buquicchio, Maria Teresa Ventura, Pier Luigi Traetta, Saverio Nenna, Giuseppe Iadarola, Thea Magrone
BACKGROUND: Allergy to Anisakis simplex (s.) is spreading due to the increased consumption of raw, smoked or marinated fish. In humans, Anisakis s. can directly attack the gastrointestinal mucosa, provoking a parasitosis known as anisakiasis, or giving rise to the formation of IgE and, finally, inducing IgE-mediated reactions like urticaria, angioedema and anaphylactic shock. During recent years, a dietary approach to Anisakis s. infestation has also been addressed. METHODS: A total of 620 patients with urticaria, angioedema, or both and a history of anaphylaxis following consumption of raw, smoked or marinated fish were recruited, evaluated for specific IgE levels to Anisakis s...
November 29, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29183405/socio-economic-factors-associated-with-an-increase-in-fruit-and-vegetable-consumption-a-12-year-study-in-women-from-the-e3n-epic-study
#19
Aurélie Affret, Gianluca Severi, Courtney Dow, Francesca Romana Mancini, Grégoire Rey, Cyrille Delpierre, Françoise Clavel-Chapelon, Marie-Christine Boutron-Ruault, Guy Fagherazzi
OBJECTIVE: To identify individual and contextual socio-economic factors associated with an increase in fruit and vegetable (F&V) consumption over a 12-year period and evaluate if some socio-economic factors were differentially associated with the change in consumption of some types of F&V. DESIGN: Associations between increased F&V consumption and socio-economic factors were studied with multivariate logistic regression. SETTING: E3N, a French prospective cohort study of 98 995 women...
November 29, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29181579/mediterranean-diet-fresh-herbs-and-fresh-vegetables-decrease-the-risk-of-androgenetic-alopecia-in-males
#20
Cristina Fortes, S Mastroeni, T Mannooranparampil, D Abeni, A Panebianco
It is well established that Androgenetic Alopecia (AGA) occurs in genetically predisposed individuals but little is known of its non-genetic risk factors. The aim of the study was to investigate the role of the Mediterranean diet in determining the risk of AGA. A hospital-based case-control study was conducted in the outpatient clinics of the hospital "Istituto Dermopatico dell'Immacolata, Rome, Italy". We included 104 males and 108 controls not affected by AGA. Controls were frequency matched to cases. Information on socio-demographic characteristics, medical history, smoking and diet were collected for all patients...
November 27, 2017: Archives of Dermatological Research
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