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https://www.readbyqxmd.com/read/28301396/can-hyper-realistic-physical-models-of-peripheral-vessel-exposure-and-fasciotomy-replace-cadavers-for-performance-assessment
#1
Jeremy Holzmacher, Babak Sarani, Adam Puche, Guinevere Granite, Valerie Shalin, Kristy Pugh, William Teeter, Samuel Tisherman, Stacy Shackelford, Colin F Mackenzie
BACKGROUND: Work-hour restrictions have reduced operative experience for residents. The Advanced Surgical Skills for Exposure in Trauma course fills this training gap. Cadaver use has limitations including cost and availability. Hyper-realistic synthetic models may provide an alternative to cadavers. We compared same surgeon performance between synthetic and cadaveric models to determine interchangeability for formative evaluation. METHODS: 40 residents (<4wks after ASSET) and 35 faculty (mean 2...
March 15, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28299536/associations-between-the-readiness-for-return-to-work-scale-and-return-to-work-a-prospective-study
#2
Lene Aasdahl, Kristine Pape, Chris Jensen, Ottar Vasseljen, Tore Braathen, Roar Johnsen, Marius Steiro Fimland
Purpose To explore the usefulness of the Readiness for return to work scale in individuals participating in occupational rehabilitation, by assessing the association between the scale and return to work (RTW), and comparing the scale to a question assessing individuals' expectations about length of sick leave. Method Prospective cohort study with 9 months follow-up. Participants took part in one of two randomized clinical trials. Associations between the Readiness for RTW scale and RTW was analyzed using linear and logistic regression, with adjustment for age, gender and education...
March 16, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28298689/postharvest-application-of-brassica-meal-derived-allyl-isothiocyanate-to-kiwifruit-effect-on-fruit-quality-nutraceutical-parameters-and-physiological-response
#3
Luisa Ugolini, Laura Righetti, Katya Carbone, Roberta Paris, Lorena Malaguti, Alessandra Di Francesco, Laura Micheli, Mariano Paliotta, Marta Mari, Luca Lazzeri
The use of natural compounds to preserve fruit quality and develop high value functional products deserves attention especially in the growing industry of processing and packaging ready-to-eat fresh-cut fruit. In this work, potential mechanisms underlying the effects of postharvest biofumigation with brassica meal-derived allyl-isothiocyanate on the physiological responses and quality of 'Hayward' kiwifruits were studied. Fruits were treated with 0.15 mg L(-1) of allyl-isothiocyanate vapours for 5 h and then stored in controlled atmosphere (2% O2, 4...
March 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28297425/investigation-on-using-high-energy-proton-beam-for-total-body-irradiation-tbi
#4
Miao Zhang, Nan Qin, Xun Jia, Wei J Zou, Atif Khan, Ning J Yue
This work investigated the possibility of using proton beam for total body irradiation (TBI). We hypothesized the broad-slow-rising entrance dose from a monoenergetic proton beam can deliver a uniform dose to patient with varied thickness. Comparing to photon-based TBI, it would not require any patient-specific compensator or beam spoiler. The hypothesis was first tested by simulating 250 MeV, 275 MeV, and 300 MeV protons irradiating a wedge-shaped water phantom in a paired opposing arrangement using Monte Carlo (MC) method...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297288/improving-treatment-plan-evaluation-with-automation
#5
Elizabeth L Covington, Xiaoping Chen, Kelly C Younge, Choonik Lee, Martha M Matuszak, Marc L Kessler, Wayne Keranen, Eduardo Acosta, Ashley M Dougherty, Stephanie E Filpansick, Jean M Moran
The goal of this work is to evaluate the effectiveness of Plan-Checker Tool (PCT) which was created to improve first-time plan quality, reduce patient delays, increase the efficiency of our electronic workflow, and standardize and automate the physics plan review in the treatment planning system (TPS). PCT uses an application programming interface to check and compare data from the TPS and treatment management system (TMS). PCT includes a comprehensive checklist of automated and manual checks that are documented when performed by the user as part of a plan readiness check for treatment...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28294008/nurses-are-human-beings-too
#6
Jimmy Neeson
Your story 'Thousands of nurses leave NHS posts to maintain work-life balance' (online news, 3 March) made me think. Maybe it would be better if employers didn't break the Working Time Directive, making us swap from a 12-hour night shift to a 14-hour day with no day off in-between, or two long days in a row with not enough time to go home, shower, sleep and get ready for work between them.
March 15, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28290949/dod-supported-overseas-training-rotations-in-tropical-medicine-and-global-health-2000-2015
#7
James D Mancuso, Patrick W Hickey, Rodney L Coldren, Amy K Korman, Lisa W Keep, Robert F DeFraites, Maria Smith, Luke J Mancuso, Jose L Sanchez
In 1999, the Department of Defense developed a tropical medicine training program (TMTP) to train military physicians, medical students, and scientists in performing surveillance activities in an overseas environment. This review describes the competencies, educational approach, program participants, institutional collaborations, and process outcomes of the TMTP from 2000 to 2015. TMTP-sponsored rotations addressed a wide variety of interdisciplinary competencies, many of which have military-unique applications...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28290931/prophylactic-ankle-bracing-in-military-settings-a-review-of-the-literature
#8
Thomas M Newman, Michael R Gay, W E Buckley
BACKGROUND: Within athletics and the military, ankle sprains are one of the most common injuries with the potential for long-term functional deficits. Incidence rates for ankle sprains within the military are one of the leading causes of limited duty days, especially during basic combat training, parachute training exercises, and in cadet populations. In 2008, the Department of Defense U.S. Army Center for Health Promotion and Preventative Medicine report recommended that military personnel should wear semirigid ankle braces during parachuting, basketball, soccer, and other similar high-risk activities to reduce ankle sprain injuries...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28290677/molecular-insights-into-the-translesion-synthesis-of-benzyl-guanine-from-molecular-dynamics-simulations-structural-evidence-for-mutagenic-and-non-mutagenic-replication
#9
Katie A Wilson, Stacey D Wetmore
DNA can be damaged by many compounds in our environment and the resulting damaged DNA is commonly replicated by translesion synthesis (TLS) polymerases. Since the mechanism and efficiency of TLS is affected by the type of DNA damage, obtaining information for a variety of DNA adducts is critical. However, there is no structural information for the insertion of a dNTP opposite an O6-dG adduct, which is a particularly harmful class of DNA lesions. The current work uses molecular dynamics (MD) simulations to investigate structural and energetic parameters that dictate preferred dNTP insertion opposite O6-benzyl-guanine (Bz-dG) by DNA polymerase IV (Dpo4), a prototypical TLS polymerase...
March 14, 2017: Biochemistry
https://www.readbyqxmd.com/read/28289678/improving-community-health-using-an-outcome-oriented-cqi-approach-to-community-engaged-health-professions-education
#10
Amy Clithero, Simone Jacquelyn Ross, Lyn Middleton, Carole Reeve, Andre-Jacques Neusy
Health professionals providing health-care services must have the relevant competencies and clinical experiences needed to improve population health outcomes in different contexts. Current models of health profession education often fail to produce a fit-for-purpose workforce ready and willing to provide relevant, quality care to underserved communities. Evidence is emerging that community-engaged and socially accountable health workforce education, i.e., aligned with priority health needs, produces a workforce ready and willing to work in partnership with underserved regions...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28278228/bids-apps-improving-ease-of-use-accessibility-and-reproducibility-of-neuroimaging-data-analysis-methods
#11
Krzysztof J Gorgolewski, Fidel Alfaro-Almagro, Tibor Auer, Pierre Bellec, Mihai Capotă, M Mallar Chakravarty, Nathan W Churchill, Alexander Li Cohen, R Cameron Craddock, Gabriel A Devenyi, Anders Eklund, Oscar Esteban, Guillaume Flandin, Satrajit S Ghosh, J Swaroop Guntupalli, Mark Jenkinson, Anisha Keshavan, Gregory Kiar, Franziskus Liem, Pradeep Reddy Raamana, David Raffelt, Christopher J Steele, Pierre-Olivier Quirion, Robert E Smith, Stephen C Strother, Gaël Varoquaux, Yida Wang, Tal Yarkoni, Russell A Poldrack
The rate of progress in human neurosciences is limited by the inability to easily apply a wide range of analysis methods to the plethora of different datasets acquired in labs around the world. In this work, we introduce a framework for creating, testing, versioning and archiving portable applications for analyzing neuroimaging data organized and described in compliance with the Brain Imaging Data Structure (BIDS). The portability of these applications (BIDS Apps) is achieved by using container technologies that encapsulate all binary and other dependencies in one convenient package...
March 9, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28277202/facilitative-components-of-collaborative-learning-a-review-of-nine-health-research-networks
#12
Lisa Leroy, Jessica Levin Rittner, Karin E Johnson, Jessie Gerteis, Therese Miller
OBJECTIVE: Collaborative research networks are increasingly used as an effective mechanism for accelerating knowledge transfer into policy and practice. This paper explored the characteristics and collaborative learning approaches of nine health research networks. DATA SOURCES/STUDY SETTING: Semi-structured interviews with representatives from eight diverse US health services research networks conducted between November 2012 and January 2013 and program evaluation data from a ninth...
February 2017: Healthcare Policy, Politiques de Santé
https://www.readbyqxmd.com/read/28271111/syntheses-of-c17-c27-fragments-of-20-deoxybryostatins-for-assembly-using-julia-and-metathesis-reactions
#13
Matthew Ball, Thomas Gregson, Hiroki Omori, Eric J Thomas
Two approaches to the synthesis of compounds corresponding to the C17-C27 fragment of the 20-deoxybryostatins are described. The first approach is based on the palladium(0) catalysed coupling of tin enolates, generated in situ from enol acetates using tributyltin methoxide, with vinylic bromides. The vinylic bromides were prepared using the Sharpless asymmetric dihydroxylation to introduce the hydroxyl groups corresponding to those at C25 and C26 in the bryostatins. Following several steps to introduce alkynyl ester functionality, the stereoselective addition of a tributyltin cuprate followed by tributyltin-bromine exchange gave the required vinylic bromides...
March 8, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28265798/the-role-of-a-hospital-ethics-consultation-service-in-decision-making-for-unrepresented-patients
#14
Andrew M Courtwright, Joshua Abrams, Ellen M Robinson
Despite increased calls for hospital ethics committees to serve as default decision-makers about life-sustaining treatment (LST) for unrepresented patients who lack decision-making capacity or a surrogate decision-maker and whose wishes regarding medical care are not known, little is known about how committees currently function in these cases. This was a retrospective cohort study of all ethics committee consultations involving decision-making about LST for unrepresented patients at a large academic hospital from 2007 to 2013...
March 6, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28259736/health-care-professionals-readiness-for-an-interprofessional-orthogeriatric-unit-a-cross-sectional-survey
#15
Charlotte Abrahamsen, Birgitte Nørgaard, Eva Draborg
An assessment of readiness for change can set the stage for the implementation by providing information regarding staff members' beliefs and attitudes prior to an organizational change. We conducted a cross-sectional survey to assess readiness for change (N = 113 employees) in a hospital on the verge of implementing an interprofessional, co-managed orthogeriatric unit. Staff members from three departments with roles related to orthogeriatric patients were invited to answer a web-based questionnaire. Our survey demonstrates that health care professionals are confident that interprofessional collaboration will be promoted by the implementation of orthogeriatric care...
November 11, 2016: International Journal of Orthopaedic and Trauma Nursing
https://www.readbyqxmd.com/read/28259522/intensive-care-nurses-experiences-and-perceptions-of-delirium-and-delirium-care
#16
Katarzyna Zamoscik, Rosemary Godbold, Pauline Freeman
OBJECTIVE: To explore nurses' experiences and perceptions of delirium, managing delirious patients, and screening for delirium, five years after introduction of the Confusion Assessment Method for Intensive Care into standard practice. RESEARCH DESIGN AND SETTING: Twelve nurses from a medical-surgical intensive care unit in a large teaching hospital attended two focus group sessions. The collected qualitative data was thematically analysed using Braun and Clarke's framework (2006)...
March 1, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28248626/ready-for-ehealth-health-professionals-acceptance-and-adoption-of-ehealth-interventions-in-inpatient-routine-care
#17
Severin Hennemann, Manfred E Beutel, Rüdiger Zwerenz
eHealth interventions can be effective in treating health problems. However, adoption in inpatient routine care seems limited. The present study therefore aimed to investigate barriers and facilitators to acceptance of eHealth interventions and of online aftercare in particular in health professionals of inpatient treatment. A total of 152 out of 287 health professionals of various professional groups in four inpatient rehabilitation facilities filled out a self-administered web-based questionnaire (response rate: 53%); 128 individuals were eligible for further data analysis...
March 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/28239485/protocol-for-the-evaluation-of-a-digital-storytelling-approach-to-address-stigma-and-improve-readiness-to-seek-services-among-veterans
#18
Brian E Bunnell, Tatiana M Davidson, Jessica L Hamblen, Danna L Cook, Anouk L Grubaugh, Brian E Lozano, Peter W Tuerk, Kenneth J Ruggiero
BACKGROUND: Research suggests that at least 10% of veterans returning from Iraq and Afghanistan meet criteria for posttraumatic stress disorder (PTSD) related to their military experiences. National dissemination initiatives have increased veterans' access to best-practice interventions. However, treatment-seeking remains low among veterans with PTSD, often due to perceived stigma and other associated barriers. The National Center for PTSD recently developed and launched AboutFace, a digital storytelling (DST) resource designed to help veterans recognize PTSD and motivate them to seek evidence-based treatment...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28236389/early-mobilization-of-mechanically-ventilated-patients
#19
REVIEW
Pam Hruska
Critically ill patients requiring mechanical ventilation are least likely to be mobilized and, as a result, are at-risk for prolonged complications from weakness. The use of bed rest and sedation when caring for mechanically ventilated patients is likely shaped by historical practice; however, this review demonstrates early mobilization, with little to no sedation, is possible and safe. Assessing readiness for mobilization in context of progressing patients from passive to active activities can lead to long-term benefits and has been achievable with resource-efficient implementations and team work...
December 2016: Critical Care Nursing Clinics of North America
https://www.readbyqxmd.com/read/28231289/rehr-an-r-package-for-manipulating-and-analysing-electronic-health-record-data
#20
David A Springate, Rosa Parisi, Ivan Olier, David Reeves, Evangelos Kontopantelis
Research with structured Electronic Health Records (EHRs) is expanding as data becomes more accessible; analytic methods advance; and the scientific validity of such studies is increasingly accepted. However, data science methodology to enable the rapid searching/extraction, cleaning and analysis of these large, often complex, datasets is less well developed. In addition, commonly used software is inadequate, resulting in bottlenecks in research workflows and in obstacles to increased transparency and reproducibility of the research...
2017: PloS One
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