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https://www.readbyqxmd.com/read/28326433/application-of-electronic-algorithms-to-improve-diagnostic-evaluation-for-bladder-cancer
#1
Daniel R Murphy, Ashley N D Meyer, Viralkumar Vaghani, Elise Russo, Dean F Sittig, Kyle A Richards, Li Wei, Louis Wu, Hardeep Singh
BACKGROUND: Strategies to ensure timely diagnostic evaluation of hematuria are needed to reduce delays in bladder cancer diagnosis. OBJECTIVE: To evaluate the performance of electronic trigger algorithms to detect delays in hematuria follow-up. METHODS: We developed a computerized trigger to detect delayed follow-up action on a urinalysis result with high-grade hematuria (>50 red blood cells/high powered field). The trigger scanned clinical data within a Department of Veterans Affairs (VA) national data repository to identify all patient records with hematuria, then excluded those where follow-up was unnecessary (e...
March 22, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28325786/impact-on-hospital-resources-of-systematic-evaluation-and-management-of-suspected-nonaccidental-trauma-in-patients-less-than-4-years-of-age
#2
Bethann M Pflugeisen, Mauricio A Escobar, Dustin Haferbecker, Yolanda Duralde, Elizabeth Pohlson
OBJECTIVE: There has been an increasing movement worldwide to create systematic screening and management procedures for atypical injury patterns in children with the hope of better detecting and evaluating nonaccidental trauma (NAT). A legitimate concern for any hospital considering implementation of a systematic evaluation process is the impact on already burdened hospital resources. We hypothesized that implementation of a guideline that uses red flags related to history, physical, or radiologic findings to trigger a standardized NAT evaluation of patients <4 years would not negatively affect resource utilization at our level II pediatric trauma center...
March 21, 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/28325780/gps-are-warned-of-costs-of-missing-red-flags-for-spinal-condition
#3
Ingrid Torjesen
No abstract text is available yet for this article.
March 20, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28316289/post-stapedectomy-granuloma-a-devastating-complication
#4
E Watts, H R F Powell, S R Saeed, R M Irving
OBJECTIVES: This paper reports three cases of severe post-stapedectomy granuloma, emphasising the variable presentation of this devastating complication and the challenges of its management. METHODS: A retrospective review was conducted of three cases of post-stapedectomy granuloma requiring surgical debulking between 2010 and 2015. Clinical symptoms, serial imaging, histopathology and post-operative outcomes were considered. RESULTS: Intra-operatively, extensive granulation tissue with erosion of the otic capsule was found...
March 20, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28315047/putting-dementia-awareness-into-general-practice-the-cadif-approach
#5
Michael Pentzek, Horst Christian Vollmar, Stefan Wilm, Verena Leve
BACKGROUND: International studies show that dementia is often recognized at later stages in general practice. Pure knowledge-sharing interventions could not change this in a sustainable manner. Concepts for changing attitudes of general practitioners (GPs) are required. OBJECTIVES: What barriers affect GPs' recognition of and diagnostic approach to dementia? What recommendations for a GP-specific diagnostic procedure can be derived from this? METHODS: Metasynthesis of qualitative studies with GPs on barriers to dementia recognition, explication of the "frailty" concept and the diagnostic approach described therein and the development of an approach in cases of suspected cognitive decline in a multiprofessional team...
March 17, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28314419/eye-and-orbital-injuries-in-sports
#6
REVIEW
Jonathan A Micieli, Michael Easterbrook
Sports-related eye and orbital injuries continue to occur regularly and may have serious consequences. They are completely preventable when appropriate protection is worn, particularly with polycarbonate lenses. Eye protection is available for most sports and should be worn in accordance with the standards of regional authorities. It is important for first responders to identify red flags in the history and physical examination of an injured athlete for urgent referral to an ophthalmologist. Common sports-related eye injuries include corneal abrasion, subconjunctival hemorrhage, hyphema, vitreous hemorrhage, retinal tears and detachment...
April 2017: Clinics in Sports Medicine
https://www.readbyqxmd.com/read/28301580/deep-roots-delay-flowering-and-relax-the-impact-of-floral-traits-and-associated-pollinators-in-steppe-plants
#7
Rachda Berrached, Leila Kadik, Hocine Ait Mouheb, Andreas Prinzing
Strong seasonality in abiotic harshness and pollinator availability shape the reproductive success of plants. Plant species can avoid or can tolerate harsh abiotic conditions and can attract different pollinators, but it remains unknown (i) which of these capacities is most important for flowering phenology, (ii) whether tolerance/avoidance of abiotic harshness reinforces or relaxes the phenological differentiation of species attracting different pollinators. We assembled possibly the first functional trait database for a North African steppe covering 104 species...
2017: PloS One
https://www.readbyqxmd.com/read/28297240/analytical-comparison-between-two-hematological-analyzer-systems-cal-8000-vs-xn-9000
#8
COMPARATIVE STUDY
S Buoro, T Mecca, M Seghezzi, B Manenti, G Azzarà, P Dominoni, A Crippa, C Ottomano, G Lippi
INTRODUCTION: This study was aimed to compare the analytical performance of traditional and new parameters and morphological flags of CAL-8000 and XN-9000. The automated differential leukocyte count (DIFF profile) and morphological flags were compared with optical microscopy (OM). METHODS: A total of 1025 peripheral blood samples, collected in K3 EDTA tubes, were analyzed by CAL-8000, by XN-9000, and by OM. Within-run imprecision was performed in low cellularity samples...
April 2017: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/28284822/-algorithms-and-urinary-incontinence-in-the-elderly-assessment-treatment-recommendations-and-levels-of-evidence-review
#9
P Meyer
OBJECTIVES: Search processing algorithms in a primary care setting, analyzing the specifics of care management for seniors suffering from urinary incontinence (UI), described the recommendations and levels of evidence of treatment. METHODS: A literature review carried out via PubMed(®) and websites of scientific societies with search keywords classified according to an algorithm. RESULTS: One hundred algorithms have been discovered in the field of evaluation and treatment of UI...
March 8, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28283964/recurrent-gastrointestinal-disturbance-abdominal-migraine-and-cyclic-vomiting-syndrome
#10
REVIEW
Samantha Irwin, Rebecca Barmherzig, Amy Gelfand
Primary headache disorders, including migraine, are some of the most common neurological disorders presenting to hospital. Episodic syndromes that may be associated with migraine, including recurrent gastrointestinal disturbances such as abdominal migraine and cyclic vomiting, often pre-date or co-occur with the onset of migraine in a child who is at risk of developing the headache condition. The purpose of this review is to evaluate the two most common episodic syndromes, abdominal migraine and cyclic vomiting syndrome, including their pathophysiology, common presentations, and diagnostic criteria...
March 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28283106/vogt-koyanagi-harada-syndrome-mimicking-multiple-sclerosis-a-case-report-and-review-of-the-literature
#11
REVIEW
Hussein Algahtani, Bader Shirah, Raghad Algahtani, Abdulah Alkahtani, Saeed Alwadie
Vogt Koyanagi Harada (VKH) Syndrome, also called uveomeningioencephalitis, is a chronic disorder characterized by inflammation of the uvea, meninges, auditory system, and integumentary system. The association between VKH syndrome and multiple sclerosis (MS) has been reported only once in the literature in a patient who developed VKH syndrome after two years of the diagnosis of MS. In this article, we report a case who was misdiagnosed and treated as MS until she was proven to have VKH syndrome, and a diagnosis of MS was excluded...
February 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28282809/how-i-do-it-clinical-application-of-brain-mri-in-the-diagnostic-work-up-of-parkinsonism
#12
Frederick J A Meijer, Bozena Goraj, Bastiaan R Bloem, Rianne A J Esselink
Differentiating Parkinson's disease and atypical parkinsonism on clinical parameters is challenging, especially in early disease courses. This is due to large overlap in symptoms and because the so called red flags, i.e. symptoms indicating atypical parkinsonism, have not (fully) developed. Brain MRI can aid to improve the accuracy and confidence about the diagnosis. The main purpose of brain MRI is to assess cerebrovascular damage, and to exclude other possible - and sometimes treatable - causes of parkinsonism, such as normal pressure hydrocephalus...
March 6, 2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/28282604/the-fecal-occult-blood-test-as-a-tool-for-improved-outpatient-qualification-for-colonoscopy-a-single-center-experience-and-10-year-follow-up-survey
#13
Zbigniew Banaszkiewicz, Jacek Budzyński, Krzysztof Tojek, Paweł Jarmocik, Jacek Frasz, Marcin Mrozowski, Maciej Świtoński, Arkadiusz Jawień
PURPOSE: Colonoscopy is not widely and easily available in all countries, even for symptomatic patients. This is one of the causes of tumors not being diagnosed until an advanced stage. The aim of this study was to estimate the efficacy of the fecal occult blood test (FOBT) in the diagnostic work-up of outpatients referred to a colorectal unit due to indistinct abdominal symptoms. PATIENTS/METHODS: Among 10418 consecutive symptomatic individuals referred to the outpatient clinic, an immunochemical FOBT (Hem-Check 1(®)) was recommended for 9432 patients with indistinct symptoms as a tool for qualifying them for colonoscopy...
March 7, 2017: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28261116/red-flags-clinical-signs-for-identifying-autoimmune-encephalitis-in-psychiatric-patients
#14
Julia Herken, Harald Prüss
Autoimmune mechanisms causing diverse psychiatric symptoms are increasingly recognized and brought about a paradigm shift in neuropsychiatry. Identification of underlying antibodies against neuronal ion channels or receptors led to the speculation that a number of patients go misdiagnosed with a primary psychiatric disease. However, there is no clear consensus which clinical signs in psychiatric patients should prompt further investigations including measurement of anti-neuronal autoantibodies. We therefore aimed to analyze the presenting symptoms in patients with autoimmune encephalitis and the time between symptom onset and initiation of antibody diagnostics...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28260272/lisfranc-injuries
#15
Sacha Wynter, Cameron Grigg
BACKGROUND: Injury to the tarsometatarsal joint is a relatively rare occurrence that is commonly missed, leading to debilitating outcomes. For this reason, it is considered a red flag in general practice. OBJECTIVE: This article reviews the current literature on tarsometatarsal injuries and describes clinical assessment, imaging and management. DISCUSSION: Lisfranc injuries refer to the displacement of the metatarsals from the tarsus, with special attention placed on the second tarsometa-tarsal joint and Lisfranc ligament...
March 2017: Australian Family Physician
https://www.readbyqxmd.com/read/28260265/managing-corneal-foreign-bodies-in-office-based-general-practice
#16
Alison Fraenkel, Lawrence R Lee, Graham A Lee
BACKGROUND: Patients with a corneal foreign body may first present to their general practitioner (GP). Safe and efficacious management of these presentations avoids sight-threatening and eye-threatening complications. Removal of a simple, superficial foreign body without a slit lamp is within The Royal Australian College of General Practitioners' (RACGP's) curriculum and scope of practice. Knowing the rele-vant procedural skills and indications for referral is equally important. OBJECTIVE: The objective of this article is to provide an evidence-based and expert-based guide to the management of corneal foreign bodies in the GP's office...
March 2017: Australian Family Physician
https://www.readbyqxmd.com/read/28257919/progressing-moodswings-the-upgrade-and-evaluation-of-moodswings-2-0-an-online-intervention-for-bipolar-disorder
#17
S Lauder, V E Cosgrove, E Gliddon, D Grimm, S Dodd, L Berk, D Castle, T S Suppes, M Berk
MoodSwings 2.0 is a self-guided online intervention for bipolar disorder. The intervention incorporates technological improvements on an earlier validated version of the intervention (MoodSwings 1.0). The previous MoodSwings trial provides this study with a unique opportunity to progress previous work, whilst being able to take into consideration lesson learnt, and technological enhancements. The structure and technology of MoodSwings 2.0 are described and the relevance to other online health interventions is highlighted...
February 28, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28254744/review-of-criterion-referenced-standards-for-cardiorespiratory-fitness-what-percentage-of-1%C3%A2-142%C3%A2-026-international-children-and-youth-are-apparently-healthy
#18
Justin J Lang, Mark S Tremblay, Francisco B Ortega, Jonatan R Ruiz, Grant R Tomkinson
PURPOSE: To identify criterion-referenced standards for cardiorespiratory fitness (CRF); to estimate the percentage of children and youth that met each standard; and to discuss strategies to help improve the utility of criterion-referenced standards for population health research. METHODS: A search of four databases was undertaken to identify papers that reported criterion-referenced CRF standards for children and youth generated using the receiver operating characteristic curve technique...
March 2, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28251880/choosing-wisely-canada%C3%A2-five-tests-procedures-and-treatments-to-question-in-emergency-medicine
#19
Amy H Y Cheng, Sam Campbell, Lucas B Chartier, Tom Goddard, Kirk Magee, Jill McEwen, Atul K Kapur, Brian R Holroyd, Suneel Upadhye, Stephanie Couperthwaite, Brian H Rowe
OBJECTIVES: Choosing Wisely Canada (CWC) is an initiative to encourage patient-physician discussions about the appropriate, evidence based use of medical tests, procedures and treatments. We present the Canadian Association of Emergency Physicians' (CAEP) top five list of recommendations, and the process undertaken to generate them. METHODS: The CAEP Expert Working Group (EWG) generated a candidate list of 52 tests, procedures, and treatments in emergency medicine whose value to care was questioned...
March 2, 2017: CJEM
https://www.readbyqxmd.com/read/28243926/comparing-three-different-modes-of-electroretinography-in-experimental-glaucoma-diagnostic-performance-and-correlation-to-structure
#20
Laura Wilsey, Sowjanya Gowrisankaran, Grant Cull, Christy Hardin, Claude F Burgoyne, Brad Fortune
PURPOSE: To compare diagnostic performance and structure-function correlations of multifocal electroretinogram (mfERG), full-field flash ERG (ff-ERG) photopic negative response (PhNR) and transient pattern-reversal ERG (PERG) in a non-human primate (NHP) model of experimental glaucoma (EG). METHODS: At baseline and after induction of chronic unilateral IOP elevation, 43 NHP had alternating weekly recordings of retinal nerve fiber layer thickness (RNFLT) by spectral domain OCT (Spectralis) and retinal function by mfERG (7F slow-sequence stimulus, VERIS), ff-ERG (red 0...
February 27, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
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