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https://www.readbyqxmd.com/read/29779295/neck-pain-what-if-it-is-not-musculoskeletal
#1
Nirosen Vijiaratnam, David R Williams, Kelly L Bertram
BACKGROUND: Neck pain is a common presentation in general practice, with muscle strain or osteoarthritis the most common diagnoses. A systematic approach for identifying red flags for alternative causes is required to appropriately investigate or refer for specialist opinion. OBJECTIVE: The aim of this article is to highlight features of neurological and other causes of neck pain in adults that may present in general practice, and to outline a quick and practical diagnostic approach...
May 2018: Australian journal of general practice
https://www.readbyqxmd.com/read/29779011/fifteen-minute-consultation-red-flags-for-metabolic-disease-in-routine-bloods
#2
Caroline Hart, James E Davison, Maureen A Cleary
No abstract text is available yet for this article.
May 19, 2018: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/29750288/recognizing-and-managing-children-with-a-pediatric-cancer-predisposition-syndrome-a-guide-for-the-pediatrician
#3
Stephanie A Coury, Katherine A Schneider, Jaclyn Schienda, Wen-Hann Tan
It is estimated that at least 8% to 10% of children diagnosed with cancer have an inherited cancer predisposition syndrome. Pediatricians may be called upon to (1) identify children with symptoms suggestive of cancer that require further diagnostic testing, (2) identify children who should be referred to cancer genetics based on their personal and family histories, and (3) provide primary care to children who have an inherited cancer syndrome. This review article provides a list of clinical warning signs suggestive of childhood malignancy, discusses the personal and family history "red flags" suggestive of hereditary cancer, offers checklists to help identify patients who are candidates for cancer genetics evaluation, and describes features of the major pediatric cancer syndromes involving solid tumors and surveillance guidelines...
May 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29742060/renal-involvement-in-autoinflammatory-diseases-and-inflammasome-mediated-chronic-kidney-damage
#4
REVIEW
Roberto Scarpioni, Laura Obici
Unprovoked activation of innate immune pathways and increased secretion of interleukin (IL)-1β and IL-18 are responsible for the protean clinical manifestations and the marked inflammatory response that characterise most hereditary autoinflammatory disorders. The kidney is a major target organ of this inflammatory process. The deposition of the acute-phase reactant serum amyloid A (SAA) as amyloid causes progressive glomerular and vascular damage and leads to organ failure. In this review we focus on the potential impact of hereditary autoinflammatory diseases on renal function, provide red flags that may guide the clinical suspicion of amyloid kidney damage and discuss the relevance of close renal monitoring for early diagnosis and prompt treatment...
January 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29739701/early-identification-of-epileptic-encephalopathy-with-continuous-spikes-and-waves-during-sleep-a-case-control-study
#5
Camille Desprairies, Blandine Dozières-Puyravel, Adina Ilea, Vanina Bellavoine, Hala Nasser, Catherine Delanöe, Stéphane Auvin
Epileptic encephalopathy with continuous spikes-and-waves during sleep (EE-CSWS) is a rare childhood epilepsy syndrome characterized by a regression in cognitive, behavioral and psychiatric functioning, seizures and a specific electroencephalographic pattern. An early recognition and an appropriate treatment might play a key role in the outcome of this epileptic encephalopathy. We conducted a case-control study to evaluate if there is any clinical or electroencephalographic sign suggestive of EE-CSWS after the first seizure...
April 27, 2018: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29732270/is-snapchat-dysmorphia-a-real-issue
#6
EDITORIAL
Kamleshun Ramphul, Stephanie G Mejias
It was observed that in early 2018, several newspapers raised a concern about the negative effects of social media applications, such as Snapchat and Instagram, on users related to the choice of plastic surgeries. Several plastic surgeons have shared their experiences whereby they encountered requests sounding similar to what a "filtered" Snapchat picture would look like, with one plastic surgeon even having a patient who actually produced a "filtered" image. There are several red flags to look out for in such patients, and proper management in those cases should include counseling and not plastic surgery...
March 3, 2018: Curēus
https://www.readbyqxmd.com/read/29730460/imaging-for-low-back-pain-is-clinical-use-consistent-with-guidelines-a-systematic-review-and-meta-analysis
#7
Hazel J Jenkins, Aron S Downie, Chris G Maher, Niamh A Moloney, John S Magnussen, Mark J Hancock
BACKGROUND CONTEXT: The problem of imaging patients with low back pain (LBP) when it is not indicated is well recognised. The converse is also possible, although rarely considered. The extent of these two problems is presently unclear. PURPOSE: To estimate how commonly overuse, and also underuse, of imaging occurs in the management of LBP, and how appropriate use of imaging is assessed. DESIGN: Systematic review and meta-analysis PATIENT SAMPLE: Patients with low back pain presenting to primary care...
May 3, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29730269/atrioesophageal-fistula-considerations-for-the-neurological-clinician
#8
Laura A Zima, Linden E Fornoff, Daniel L Surdell
Atrioesophageal fistula (AEF) is a rare complication of cardiac ablation for atrial fibrillation. It can present in many ways, but neurological signs and symptoms are common initial signs sometimes resulting in neurosurgeons and neurologists first evaluating patients with the condition. We present a case report of at 68-year-old female who presented with acute stroke symptoms and multifocal hemorrhages on MRI who was worked up through our neurosurgery department and diagnosed with AEF. This case highlights three clues to alert neurological clinicians to AEF as a possible diagnosis; clinical worsening of neurological symptoms in correlation to episodes of emesis, septic emboli on CT/MRI, and bacteremia caused by a gram positive oral or GI flora...
April 27, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29728151/development-and-validation-of-a-pre-hospital-red-flag-alert-for-activation-of-intra-hospital-haemorrhage-control-response-in-blunt-trauma
#9
Sophie Rym Hamada, Anne Rosa, Tobias Gauss, Jean-Philippe Desclefs, Mathieu Raux, Anatole Harrois, Arnaud Follin, Fabrice Cook, Mathieu Boutonnet, Arie Attias, Sylvain Ausset, Mathieu Boutonnet, Gilles Dhonneur, Jacques Duranteau, Olivier Langeron, Catherine Paugam-Burtz, Romain Pirracchio, Guillaume de St Maurice, Bernard Vigué, Alexandra Rouquette, Jacques Duranteau
BACKGROUND: Haemorrhagic shock is the leading cause of early preventable death in severe trauma. Delayed treatment is a recognized prognostic factor that can be prevented by efficient organization of care. This study aimed to develop and validate Red Flag, a binary alert identifying blunt trauma patients with high risk of severe haemorrhage (SH), to be used by the pre-hospital trauma team in order to trigger an adequate intra-hospital standardized haemorrhage control response: massive transfusion protocol and/or immediate haemostatic procedures...
May 5, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29724224/mog-encephalomyelitis-international-recommendations-on-diagnosis-and-antibody-testing
#10
REVIEW
S Jarius, F Paul, O Aktas, N Asgari, R C Dale, J de Seze, D Franciotta, K Fujihara, A Jacob, H J Kim, I Kleiter, T Kümpfel, M Levy, J Palace, K Ruprecht, A Saiz, C Trebst, B G Weinshenker, B Wildemann
Over the past few years, new-generation cell-based assays have demonstrated a robust association of autoantibodies to full-length human myelin oligodendrocyte glycoprotein (MOG-IgG) with (mostly recurrent) optic neuritis, myelitis and brainstem encephalitis, as well as with acute disseminated encephalomyelitis (ADEM)-like presentations. Most experts now consider MOG-IgG-associated encephalomyelitis (MOG-EM) a disease entity in its own right, immunopathogenetically distinct from both classic multiple sclerosis (MS) and aquaporin-4 (AQP4)-IgG-positive neuromyelitis optica spectrum disorders (NMOSD)...
May 3, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29724172/a-randomized-controlled-trial-testing-the-effectiveness-of-a-paramedic-delivered-care-transitions-intervention-to-reduce-emergency-department-revisits
#11
Ranran Mi, Matthew M Hollander, Courtney M C Jones, Eva H DuGoff, Thomas V Caprio, Jeremy T Cushman, Amy J H Kind, Michael Lohmeier, Manish N Shah
BACKGROUND: Approximately 20% of community-dwelling older adults discharged from the emergency department (ED) return to an ED within 30 days, an occurrence partially resulting from poor care transitions. Prior published interventions to improve the ED-to-home transition have either lacked feasibility or effectiveness. The Care Transitions Intervention (CTI) has been validated to decrease rehospitalization among patients transitioning from the hospital to the home but has never been tested for patients transitioning from the ED to the home...
May 3, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29716976/visual-diagnosis-visual-impairment-polydactyly-and-obesity-red-flags-in-a-child
#12
Hitesh Agrawal, Gunjan Dokania, Hugh D Allen
No abstract text is available yet for this article.
May 2018: Pediatrics in Review
https://www.readbyqxmd.com/read/29700039/nose-and-sinus-tumours-red-flags-and-referral
#13
Christopher A Slinger, Gerald W McGarry
No abstract text is available yet for this article.
May 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/29686538/hymenoptera-sting-reactions-in-southern-italy-forestry-workers-our-experience-compared-to-reported-data
#14
Luisa Ricciardi, Francesco Papia, Giuseppe Cataldo, Mario Giorgianni, Giovanna Spatari, Sebastiano Gangemi
Background: Hymenoptera sting reactions are among life-threatening causes of allergy. Several epidemiology studies have assessed the risk of these kind of reactions, among the general population, around 3% of adults. This incidence increases among highly at risk populations such as outdoor workers. Hymenoptera stings among forestry workers (FW) are occupational triggers but it has not yet been well defined which is the real incidence of anaphylaxis in these workers, not even in Italy...
2018: Clinical and Molecular Allergy: CMA
https://www.readbyqxmd.com/read/29686480/physical-therapy-clinical-specialization-and-management-of-red-and-yellow-flags-in-patients-with-low-back-pain-in-the-united-states
#15
Carlos E Ladeira
Objectives: Physical therapists (PTs) may practice in direct access or act as primary care practitioners, which necessitate patients' screening and management for red, orange and yellow flags. The objective of the project was to assess the American PT's ability to manage red, orange and yellow flags in patients with low back pain (LBP), and to compare this ability among PTs with different qualifications. Methods: The project was an electronic cross-sectional survey...
May 2018: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/29679174/sleep-abnormalities-in-multiplesystem-atrophy
#16
REVIEW
Valérie Cochen De Cock
PURPOSE OF REVIEW: The purpose of this review was to explore the different sleep disorders associated with MSA, their mechanisms, and their treatments. RECENT FINDINGS: Stridor is a red flag for the diagnosis of MSA. Recent findings show that its presence in early stage of the disease is associated with a reduction in life expectancy. Its management should be fast and adapted. Its treatment with continuous positive airway pressure or tracheostomy is efficacious...
April 20, 2018: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/29676831/correlations-between-histopathologic-and-dermoscopic-findings-in-korean-actinic-keratosis
#17
Dong Won Lee, Dae Yeon Kim, Ji Hyuck Hong, Soo Hong Seo, Young Chul Kye, Hyo Hyun Ahn
Skin biopsy for AK diagnosis is usually performed on only a limited part of the whole lesion. Therefore, a clinical diagnosis is important. According to a study, there is no significant correlation between histopathological and clinical classification system. We examined the correlation between microscopic information and dermoscopic findings to deduce if dermoscopic information reflects histopathologic grade severity. Forty seven patients with histologically confirmed AK were enrolled and positive ratio of red pseudonetwork, rosette, red background and targetoid signs, white-to-yellow scale, white structureless area, and pigmentation from dermoscopic findings were investigated...
April 20, 2018: Microscopy Research and Technique
https://www.readbyqxmd.com/read/29675548/exercise-headache-a-review
#18
REVIEW
Claire H Sandoe, William Kingston
PURPOSE OF REVIEW: Exercise headache refers to headache that is triggered by exercise or exertion. Although secondary causes must be excluded, most cases of exercise headache are benign, idiopathic, and self-limited. This article reviews the revised diagnostic criteria for primary exercise headache (PEH) and discusses recent research into the clinical presentation, epidemiology, pathophysiology, suggested workup, and treatment of this condition. RECENT FINDINGS: Recent studies estimate that PEH affects from 1 to 26% of the adult population...
April 19, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29673820/extra-osseous-ewing-s-sarcoma-of-sciatic-nerve-masquerading-as-benign-nerve-sheath-tumor-and-presented-as-lumbar-radiculopathy
#19
Jung Soo Bang, Nitin Adsul, Jae-Hyeon Lim, Il-Tae Jang
BACKGROUND: Extraosseous Ewing Sarcoma (EES) arising from peripheral nerves is extremely rare with only 11 cases, mentioned in the literature. It poses a diagnostic challenge to the clinicians due to its nonspecific presentation and rare occurrence. CASE DESCRIPTION: A 56-year-old woman came with a history of low back pain and intractable right leg pain. Physical examination revealed the normal motor power of both lower limbs with decreased sensation along the lateral aspect of the foot with decreased ankle reflex...
April 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29663282/the-frozen-brain-state-of-cryptococcus-gattii-a-globe-trotting-tropical-neurotropic-fungus
#20
Paul T Akins, Brian Jian
Initially reported in tropical regions, Cryptococcus gattii infection is now diagnosed globally. METHODS: case report; Literature review. Although initial reports described outbreaks of pulmonary and central nervous system (CNS) disease in tropical regions such as Australia and New Guinea, it is now clear that Cryptococcus gattii is a global, neurotropic pathogen. In contrast with C. neoformans, C. gattii patients are more likely to present with cryptococcomas in the brain and lungs and are often HIV negative...
April 16, 2018: Neurocritical Care
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