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https://www.readbyqxmd.com/read/30174772/immersed-ac-electrospray-iace-for-monodispersed-aqueous-droplet-generation
#1
Zehao Pan, Yongfan Men, Satyajyoti Senapati, Hsueh-Chia Chang
We report a new immersed alternating current (AC) electrospray droplet generation method that can generate monodispersed water-in-oil droplets, with diameters ranging from 5  μ m to 150  μ m, in a stationary oil phase. This method offers high through-put, easy size tuning, and droplets with a viscous aqueous phase at high ionic strengths (raw physiological samples). Yet, it does not require coordinated flows of the dispersed/continuous phases or even a microfluidic chip. The design relies on a small constant back pressure (less than 0...
July 2018: Biomicrofluidics
https://www.readbyqxmd.com/read/30114955/ten-guidelines-for-the-design-of-non-assembly-mechanisms-the-case-of-3d-printed-prosthetic-hands
#2
Juan Sebastian Cuellar, Gerwin Smit, Amir A Zadpoor, Paul Breedveld
In developing countries, prosthetic workshops are limited, difficult to reach, or even non-existent. Especially, fabrication of active, multi-articulated, and personalized hand prosthetic devices is often seen as a time-consuming and demanding process. An active prosthetic hand made through the fused deposition modelling technology and fully assembled right after the end of the 3D printing process will increase accessibility of prosthetic devices by reducing or bypassing the current manufacturing and post-processing steps...
September 2018: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29776116/depletion-zones-and-crystallography-on-pinched-spheres
#3
Jingyuan Chen, Xiangjun Xing, Zhenwei Yao
Understanding the interplay between ordered structures and substrate curvature is an interesting problem with versatile applications, including functionalization of charged supramolecular surfaces and modern microfluidic technologies. In this work, we investigate the two-dimensional packing structures of charged particles confined on a pinched sphere. By continuously pinching the sphere, we observe cleavage of elongated scars into pleats, proliferation of disclinations, and subsequently, emergence of a depletion zone at the negatively curved waist that is completely void of particles...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29652042/-motor-learning-of-the-post-stroke-patients-presenting-with-upper-limb-paresis-on-the-mechanotherapeutic-system
#4
A E Khizhnikova, A S Klochkov, A M Kotov-Smolensky, L A Chernikova, N A Suponeva, M A Piradov
BACKGROUND: the relevance of this study arises from the high prevalence of upper limb motor impairment and pathological synergy in the post-stroke patients; these conditions are very difficult to correct with the use of the traditional rehabilitation methods. A promising but insufficiently studied approaches are the virtual reality (VR) technology as well as its combination with other techniques. AIM: The objective of the present study was to evaluate the influence of the training making use of the mechanotherapeutic system on the motor function of the paretic hand...
April 9, 2018: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29526460/orofacial-and-thumb-index-finger-ramp-and-hold-isometric-force-dynamics-in-young-neurotypical-adults
#5
Steven M Barlow, Mohsen Hozan, Jaehoon Lee, Jake Greenwood, Rebecca Custead, Brianna Wardyn, Kaytlin Tippin
The relation among several parameters of the ramp-and-hold isometric force contraction (peak force and dF/dtmax during the initial phase of force recruitment, and the proportion of hold-phase at target) was quantified for the right and left thumb-index finger pinch, and lower lip midline compression in 40 neurotypical right-handed young adults (20 female/20 males) using wireless force sensors and data acquisition technology developed in our laboratory. In this visuomotor control task, participants produced ramp-and-hold isometric forces as 'rapidly and accurately' as possible to end-point target levels at 0...
April 27, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29470557/design-of-a-3d-printed-open-source-wrist-driven-orthosis-for-individuals-with-spinal-cord-injury
#6
Alexandra A Portnova, Gaurav Mukherjee, Keshia M Peters, Ann Yamane, Katherine M Steele
Assistive technology, such as wrist-driven orthoses (WDOs), can be used by individuals with spinal cord injury to improve hand function. A lack of innovation and challenges in obtaining WDOs have limited their use. These orthoses can be heavy and uncomfortable for users and also time-consuming for orthotists to fabricate. The goal of this research was to design a WDO with user (N = 3) and orthotist (N = 6) feedback to improve the accessibility, customizability, and function of WDOs by harnessing advancements in 3D-printing...
2018: PloS One
https://www.readbyqxmd.com/read/29391500/resistance-switching-and-memristive-hysteresis-in-visible-light-activated-adsorbed-zno-thin-films
#7
Benjamin Kerr Barnes, Kausik S Das
The discovery of resistance switching memristors marks a paradigm shift in the search for alternative non-volatile memory components in the semiconductor industry. Normally a dielectric in these bistable memory cells changes its resistance with an applied electric field or current, albeit retaining the resistive state based on the history of the applied field. Despite showing immense potential, sustainable growth of this new memory technology is bogged down by several factors including cost, intricacies of design, lack of efficient tunability, and issues with scalability and eco-friendliness...
February 1, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29334198/enzyme-based-glucose-sensor-from-invasive-to-wearable-device
#8
REVIEW
Hyunjae Lee, Yongseok Joseph Hong, Seungmin Baik, Taeghwan Hyeon, Dae-Hyeong Kim
Blood glucose concentration is a key indicator of patients' health, particularly for symptoms associated with diabetes mellitus. Because of the large number of diabetic patients, many approaches for glucose measurement have been studied to enable continuous and accurate glucose level monitoring. Among them, electrochemical analysis is prominent because it is simple and quantitative. This technology has been incorporated into commercialized and research-level devices from simple test strips to wearable devices and implantable systems...
April 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28975786/correlation-of-ion-transport-hysteresis-with-the-nanogeometry-and-surface-factors-in-single-conical-nanopores
#9
Dengchao Wang, Warren Brown, Yan Li, Maksim Kvetny, Juan Liu, Gangli Wang
Better understanding in the dynamics of ion transport through nanopores or nanochannels is important for sensing, nucleic acid sequencing and energy technology. In this paper, the intriguing nonzero cross point, resolved from the pinched hysteresis current-potential (i-V) curves in conical nanopore electrokinetic measurements, is quantitatively correlated to the surface and geometric properties by simulation studies. The analytical descriptions of the conductance and potential at the cross point are developed: the cross-point conductance includes both the surface and volumetric conductance; the cross-point potential represent the overall/averaged surface potential difference across the nanopore...
November 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28604664/quantum-tunnelling-and-charge-accumulation-in-organic-ferroelectric-memory-diodes
#10
Matteo Ghittorelli, Thomas Lenz, Hamed Sharifi Dehsari, Dong Zhao, Kamal Asadi, Paul W M Blom, Zsolt M Kovács-Vajna, Dago M de Leeuw, Fabrizio Torricelli
Non-volatile memories-providing the information storage functionality-are crucial circuit components. Solution-processed organic ferroelectric memory diodes are the non-volatile memory candidate for flexible electronics, as witnessed by the industrial demonstration of a 1 kbit reconfigurable memory fabricated on a plastic foil. Further progress, however, is limited owing to the lack of understanding of the device physics, which is required for the technological implementation of high-density arrays. Here we show that ferroelectric diodes operate as vertical field-effect transistors at the pinch-off...
June 12, 2017: Nature Communications
https://www.readbyqxmd.com/read/28467317/deep-learning-based-artificial-vision-for-grasp-classification-in-myoelectric-hands
#11
Ghazal Ghazaei, Ali Alameer, Patrick Degenaar, Graham Morgan, Kianoush Nazarpour
OBJECTIVE: Computer vision-based assistive technology solutions can revolutionise the quality of care for people with sensorimotor disorders. The goal of this work was to enable trans-radial amputees to use a simple, yet efficient, computer vision system to grasp and move common household objects with a two-channel myoelectric prosthetic hand. APPROACH: We developed a deep learning-based artificial vision system to augment the grasp functionality of a commercial prosthesis...
June 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28280725/biotechnological-processes-in-microbial-amylase-production
#12
REVIEW
Subash C B Gopinath, Periasamy Anbu, M K Md Arshad, Thangavel Lakshmipriya, Chun Hong Voon, Uda Hashim, Suresh V Chinni
Amylase is an important and indispensable enzyme that plays a pivotal role in the field of biotechnology. It is produced mainly from microbial sources and is used in many industries. Industrial sectors with top-down and bottom-up approaches are currently focusing on improving microbial amylase production levels by implementing bioengineering technologies. The further support of energy consumption studies, such as those on thermodynamics, pinch technology, and environment-friendly technologies, has hastened the large-scale production of the enzyme...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28251246/the-unseeing-state-how-ideals-of-modernity-have-undermined-innovation-in-africa-s-urban-water-systems
#13
David Nilsson
In contrast to the European historical experience, Africa's urban infrastructural systems are characterised by stagnation long before demand has been saturated. Water infrastructures have been stabilised as systems predominantly providing services for elites, with millions of poor people lacking basic services in the cities. What is puzzling is that so little emphasis has been placed on innovation and the adaptation of the colonial technological paradigm to better suit the local and current socio-economic contexts...
December 2016: NTM
https://www.readbyqxmd.com/read/28148667/the-effect-of-two-different-orthoses-on-pain-hand-function-patient-satisfaction-and-preference-in-patients-with-thumb-carpometacarpal-osteoarthritis-a-multicentre-crossover-randomised-controlled-trial
#14
RANDOMIZED CONTROLLED TRIAL
A E van der Vegt, R Grond, J S Grüschke, M F Boomsma, C H Emmelot, P U Dijkstra, C K van der Sluis
AIMS: The aim of this study was to compare the Push Ortho Thumb Brace CMC and a custom-made orthosis in the treatment of patients with primary osteoarthritis of the carpometacarpal joint of the thumb. Our outcome measures were pain scores, tests of hand function, patient satisfaction and patient preference. PATIENTS AND METHODS: A multicentre crossover randomised controlled trial was conducted which included 63 patients (44 women) with primary osteoarthritis of the carpometacarpal joint of the thumb...
February 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28104717/clinical-targeted-exome-based-sequencing-in-combination-with-genome-wide-copy-number-profiling-precision-medicine-analysis-of-203-pediatric-brain-tumors
#15
Shakti H Ramkissoon, Pratiti Bandopadhayay, Jaeho Hwang, Lori A Ramkissoon, Noah F Greenwald, Steven E Schumacher, Ryan O'Rourke, Nathan Pinches, Patricia Ho, Hayley Malkin, Claire Sinai, Mariella Filbin, Ashley Plant, Wenya Linda Bi, Michael S Chang, Edward Yang, Karen D Wright, Peter E Manley, Matthew Ducar, Sanda Alexandrescu, Hart Lidov, Ivana Delalle, Liliana C Goumnerova, Alanna J Church, Katherine A Janeway, Marian H Harris, Laura E MacConaill, Rebecca D Folkerth, Neal I Lindeman, Charles D Stiles, Mark W Kieran, Azra H Ligon, Sandro Santagata, Adrian M Dubuc, Susan N Chi, Rameen Beroukhim, Keith L Ligon
Background: Clinical genomics platforms are needed to identify targetable alterations, but implementation of these technologies and best practices in routine clinical pediatric oncology practice are not yet well established. Methods: Profile is an institution-wide prospective clinical research initiative that uses targeted sequencing to identify targetable alterations in tumors. OncoPanel, a multiplexed targeted exome-sequencing platform that includes 300 cancer-causing genes, was used to assess single nucleotide variants and rearrangements/indels...
July 1, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28078196/prosthetic-jamming-terminal-device-a-case-study-of-untethered-soft-robotics
#16
Nadia Cheng, John Amend, Todd Farrell, Debra Latour, Carlos Martinez, Jen Johansson, Anthony McNicoll, Marek Wartenberg, Samuel Naseef, William Hanson, William Culley
This article illuminates the major and often overlooked challenge of untethering soft robotic systems through the context of recent work, in which soft robotic gripper technology enabled by jamming of granular media was applied to a prosthetic jamming terminal device (PJTD). The PJTD's technical and market feasibility was evaluated in a pilot study with two upper-limb amputees. A PJTD prototype was tested against a commercial device (Motion Control electric terminal service with a one degree-of-freedom pinching mechanism) using two existing hand function tests: the first quantified the device's speed in picking and placing small blocks and the second evaluated a person's ability to perform activities of daily living (ADLs)...
December 1, 2016: Soft Robotics
https://www.readbyqxmd.com/read/27883955/prospects-for-energy-recovery-during-hydrothermal-and-biological-processing-of-waste-biomass
#17
Léda Gerber Van Doren, Roy Posmanik, Felipe A Bicalho, Jefferson W Tester, Deborah L Sills
Thermochemical and biological processes represent promising technologies for converting wet biomasses, such as animal manure, organic waste, or algae, to energy. To convert biomass to energy and bio-chemicals in an economical manner, internal energy recovery should be maximized to reduce the use of external heat and power. In this study, two conversion pathways that couple hydrothermal liquefaction with anaerobic digestion or catalytic hydrothermal gasification were compared. Each of these platforms is followed by two alternative processes for gas utilization: 1) combined heat and power; and 2) combustion in a boiler...
February 2017: Bioresource Technology
https://www.readbyqxmd.com/read/27676880/assessment-of-a-shoulder-orthosis-prototype-setting-the-upper-limb-in-a-functional-posture-a-single-case-report
#18
Mounir Beldjerd, Marie Belle, Claire Baradat, Magali Pradié, Claire Villepinte, Sylvie Hidalgo, Emilie Catella, Baptiste Gentilhomme, Thierry Cornier, David Gasq, Evelyne Castel-Lacanal, Philippe Marque, Xavier de Boissezon
OBJECTIVE: The shoulder is painful in 70% of post-stroke patients. Sling and shoulder orthosis are important for medical care. However, series slings have not proved efficiency to improve upper limb function. We realize (with OCTO31 company) a custom-made shoulder orthosis prototype (EO31) to set the upper limb in a posture with an elbow flexion, a forearm supination and, by the way, a finger extension. The objective is to facilitate the upper limb function and to decrease shoulder pain...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27671899/proctors-exploit-three-dimensional-ghost-tools-during-clinical-like-training-scenarios-a-preliminary-study
#19
COMPARATIVE STUDY
Anthony M Jarc, Andrew A Stanley, Thomas Clifford, Inderbir S Gill, Andrew J Hung
PURPOSE: In this study, we examine three-dimensional (3D) proctoring tools (i.e., semitransparent ghost tools overlaid on the surgeon's field of view) on realistic surgical tasks. Additionally, we develop novel, quantitative measures of whether proctors exploit the additional capabilities offered by ghost tools. METHODS: Seven proctor-trainee pairs completed realistic surgical tasks such as tissue dissection and suturing in a live porcine model using 3D ghost tools on the da Vinci Xi Surgical System...
June 2017: World Journal of Urology
https://www.readbyqxmd.com/read/27508341/the-pitt-innovation-challenge-pinch-driving-innovation-in-translational-research-through-an-incentive-based-problem-focused-competition
#20
Nicole Edgar Fitzpatrick, John Maier, Laurel Yasko, David Mathias, Kacy Qua, Erika Wagner, Elizabeth Miller, Steven E Reis
PROBLEM: Translational research aims to move scientific discoveries across the biomedical spectrum from the laboratory to humans, and to ultimately transform clinical practice and public health policies. Despite efforts to accelerate translational research through national initiatives, several major hurdles remain. APPROACH: The authors created the Pitt Innovation Challenge (PInCh) as an incentive-based, problem-focused approach to solving identified clinical or public health problems at the University of Pittsburgh Clinical and Translational Science Institute in spring 2014...
May 2017: Academic Medicine: Journal of the Association of American Medical Colleges
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