pinch Technology

With the growing demand for robots in the industrial field, robot-related technologies with various functions have been introduced. One notable development is the implementation of robots that operate in collaboration with human workers to share tasks, without the need of any physical barriers such as safety fences. The realization of such collaborative operations in practice necessitates the assurance of safety if humans and robots collide. Thus, it is important to establish criteria for such collision scenarios to ensure robot safety and prevent injuries...

BACKGROUND AND OBJECTIVE: The brain-computer interface (BCI) system based on steady-state visual evoked potentials (SSVEP) is expected to help disabled patients achieve alternative prosthetic hand assistance. However, the existing study still has some shortcomings in interaction aspects such as stimulus paradigm and control logic. The purpose of this study is to innovate the visual stimulus paradigm and asynchronous decoding/control strategy by integrating augmented reality technology, and propose an asynchronous pattern recognition algorithm, thereby improving the interaction logic and practical application capabilities of the prosthetic hand with the BCI system...

This study includes an examination of the design, fabrication, and experimentation of a rudimentary droplet generator. The device has potential applications in on-demand double and higher-order emulsions as well as tailored emulsions with numerous cores. The phenomenon of a pendant double droplet creation is observed when an inner phase is transported through a capillary, while a middle phase envelops the external surface of the capillary. This leads to the occurrence of a pinching-off process at the tip of the pulled capillary...

The separation of specific cell populations is instrumental in gaining insights into cellular processes, elucidating disease mechanisms, and advancing applications in tissue engineering, regenerative medicine, diagnostics, and cell therapies. Microfluidic methods for cell separation have propelled the field forward, benefitting from miniaturization, advanced fabrication technologies, a profound understanding of fluid dynamics governing particle separation mechanisms, and a surge in interdisciplinary investigations focused on diverse applications...

Research on scientific/intellectual movements, and social movements generally, tends to focus on resources and conditions outside the substance of the movements, such as funding and publication opportunities or the prestige and networks of movement actors. Drawing on Pinch's theory of technologies as institutions, I argue that research methods can also serve as resources for scientific movements by institutionalizing their ideas in research practice. I demonstrate the argument with the case of neuroscience, where the adoption of machine learning changed how scientists think about measurement and modeling of group difference...

INTRODUCTION: Upper extremity injuries are common, and often treated by occupational therapists. The need to evaluate the effectiveness of occupational therapy interventions to guide practice is pertinent. This systematic review and meta-analysis investigate the effectiveness of occupational therapy-led computer-aided interventions among adults with conditions of the hand, wrist, and forearm. METHODS: A systematic literature search of five databases was undertaken for randomized studies examining occupational therapy-led computer-aided interventions for the treatment of hand, wrist, and forearm conditions...

This study aimed to improve hand performance and play behavior in children with developmental disabilities (DD) using a remodeled glove puppetry approach. Overall, 62 children with DD were randomly assigned to experimental and control groups ( n  = 31 each). The experimental group underwent a 12-week rehabilitation program by playing with the remodeled glove puppetry, while the children in the control group played with non-remodeled glove puppetry. The Chinese puppet was remodeled using a Lego EV3® robot...

BACKGROUND: The development of touchscreen-based assessments of upper extremity function could benefit people with multiple sclerosis (MS) by allowing convenient, quantitative assessment of their condition. The Pinching Test forms a part of the Floodlight smartphone app (F. Hoffmann-La Roche Ltd, Basel, Switzerland) for people with MS and was designed to capture upper extremity function. OBJECTIVE: This study aimed to evaluate the Pinching Test as a tool for remotely assessing upper extremity function in people with MS...

We investigated the dynamics of liquid jets engendered by the impact of droplets on a fractal superhydrophobic surface. Depending on the impact conditions, jets emanate from the free liquid surface with several different shapes and velocities, sometimes accompanied by droplet ejection. Experimental outcomes exhibit two different regimes: the singular jet and columnar jet. We found that droplet impacts at a lower impact velocity and low viscosity result in singular jets, attaining a maximum velocity nearly 20-fold higher than the impact velocity...

Bread waste (BW), which is a rich source of fermentable carbohydrates, has the potential to be a sustainable feedstock for the production of Lactic acid (LA). In our previous work, LA concentration of 155.4 g/L was produced from BW via enzymatic hydrolysis, which was followed by techno-economic analysis of the bioprocess. This work evaluates the relative environmental performance of two scenarios - neutral and low pH fermentation processes for LA production from BW using a cradle to gate life cycle assessment (LCA)...

BACKGROUND: Over the past decade, the body shaping market has seen steady growth. In order to improve procedures to reduce localized fat deposits, a novel method specifically targeting subcutaneous adipose tissue was developed. OBJECTIVE: The objective of this study is to demonstrate that a novel microwave device with a frequency of 2.45 GHz achieves visible results with greater safety and consistency in reducing adipose tissue. MATERIALS AND METHODS: In all, 19 healthy patients (10 women and 9 men; age 24-55 years, average age 39 years) and visible abdominal fat received three microwave treatment sessions (each 4 weeks apart) using the new Onda Plus Body Shaping System (DEKA, Italy)...

This work presents a flux-controlled memristor structure employing a Current-Controlled Current Differencing Transconductance Amplifier (CCCDTA) with a grounded capacitor. The proposed emulator's invariant and variant parts can be safely adjustable, showing promising characteristics of up to 1.5 MHz operating frequency. Furthermore, there is no need for an additional circuit, switching mechanism or changing the circuit topology for the changing of operation modes. To justify the performance of the emulator with incremental and decremental mode operations, a Monte Carlo and temperature analysis are validated using TSMC 0...

Characterising the small intestine absorptive membrane is essential to enable prediction of the systemic exposure of oral formulations. In particular, the ontogeny of key intestinal Drug Metabolising Enzymes and Transporter (DMET) proteins involved in drug disposition needs to be elucidated to allow for accurate prediction of the PK profile of drugs in the paediatric cohort. Using pinch biopsies from the paediatric duodenum (n=36; aged 11 months to 15 years), the abundance of 21 DMET proteins and two enterocyte markers were quantified via LC-MS/MS...

Injuries involving the nervous system, such as a brachial plexus palsy or traumatic brain injury, can lead to impairment in the functionality of the hand. Assistive robotics have been proposed as a possible method to improve patient outcomes in rehabilitation. The work presented here evaluates the FLEXotendon Glove-III, a 5 degree-of-freedom, voice-controlled, tendon-driven soft robotic hand exoskeleton, with two human subjects with hand impairments and four able-bodied subjects. The FLEXotendon Glove-III was evaluated on four unimpaired subjects, in conjunction with EMG sensor data, to determine the quantitative performance of the glove in applied pinch force, perturbation resistance, and exertion reduction...

Cell fragmentation is commonly observed in human preimplantation embryos and is associated with poor prognosis during assisted reproductive technology (ART) procedures. However, the mechanisms leading to cell fragmentation remain largely unknown. Here, light sheet microscopy imaging of mouse embryos reveals that inefficient chromosome separation due to spindle defects, caused by dysfunctional molecular motors Myo1c or dynein, leads to fragmentation during mitosis. Extended exposure of the cell cortex to chromosomes locally triggers actomyosin contractility and pinches off cell fragments...

INTRODUCTION: It would be valuable if home-based rehabilitation training technologies could automatically assess arm impairment after stroke. Here, we tested whether a simple measure-the repetition rate (or "rep rate") when performing specific exercises as measured with simple sensors-can be used to estimate Upper Extremity Fugl-Meyer (UEFM) score. METHODS: 41 individuals with arm impairment after stroke performed 12 sensor-guided exercises under therapist supervision using a commercial sensor system comprised of two pucks that use force and motion sensing to measure the start and end of each exercise repetition...

Microbial production of 2,3-butanediol (BDO) has received considerable attention as a promising alternate to fossil-derived BDO. In our previous work, BDO concentration >100 g/L was accumulated using brewer's spent grain (BSG) via microbial routes which was followed by techno-economic analysis of the bioprocess. In the present work, a life cycle assessment (LCA) was conducted for BDO production from the fermentation of BSG to identify the associated environmental impacts. The LCA was based on an industrial-scale biorefinery processing of 100 metric tons BSG per day modeled using ASPEN plus integrated with pinch technology, a tool for achieving maximum thermal efficiency and heat recovery from the process...

The main challenges of liquid hydrogen (H2 ) storage as one of the most promising techniques for large-scale transport and long-term storage include its high specific energy consumption (SEC), low exergy efficiency, high total expenses, and boil-off gas losses. This article reviews different approaches to improving H2 liquefaction methods, including the implementation of absorption cooling cycles (ACCs), ejector cooling units, liquid nitrogen/liquid natural gas (LNG)/liquid air cold energy recovery, cascade liquefaction processes, mixed refrigerant systems, integration with other structures, optimization algorithms, combined with renewable energy sources, and the pinch strategy...

Arthropods are known to transmit a variety of viruses of medical and agricultural importance through their hemolymph, which is essential for virus transmission. Hemolymph collection is the basic technology for studying virus-vector interactions. Here, we describe a novel and simple method for the quantitative collection of hemolymph from small arthropods using Laodelphax striatellus (the small brown planthopper, SBPH) as a research model, as this arthropod is the main vector of rice stripe virus (RSV). In this protocol, the process begins by gently pinching off one leg of the frozen arthropod with fine-tipped tweezers and pressing the hemolymph out of the wound...

Microfluidics is a widely used tool to generate droplets and vesicles of various kinds in a controlled and high-throughput manner. Liposomes are simplistic cellular mimics composed of an aqueous interior surrounded by a lipid bilayer; they are valuable in designing synthetic cells and understanding the fundamentals of biological cells in an in vitro fashion and are important for applied sciences, such as cargo delivery for therapeutic applications. This article describes a detailed working protocol for an on-chip microfluidic technique, octanol-assisted liposome assembly (OLA), to produce monodispersed, micron-sized, biocompatible liposomes...