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Non invasive ventilation ventilators

Eric Ka Cheong Wong, Philip Cheuk Shing Lee, Saidul Ansary, Stephen Asha, Keith Hw Wong, Brendon Yee, Andrew T Ng
BACKGROUND: Many patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have type 2 respiratory failure. Often arterial blood gases (ABG) are not performed and correlation with venous blood gases (VBG) is controversial. The venous pH and bicarbonate (HCO3 ) are useful,1 but VBG PCO2 (PvCO2 ) is considered too unpredictable. We examined the utility of VBGs in this cohort of patients. PATIENTS AND METHODS: A prospective study of AECOPD patients with type 2 respiratory failure presenting to ED was performed...
December 4, 2018: Internal Medicine Journal
J Ricoy, N Rodríguez-Núñez, J M Álvarez-Dobaño, M E Toubes, V Riveiro, L Valdés
The diaphragm is the main breathing muscle and contraction of the diaphragm is vital for ventilation so any disease that interferes with diaphragmatic innervation, contractile muscle function, or mechanical coupling to the chest wall can cause diaphragm dysfunction. Diaphragm dysfunction is associated with dyspnoea, intolerance to exercise, sleep disturbances, hypersomnia, with a potential impact on survival. Diagnosis of diaphragm dysfunction is based on static and dynamic imaging tests (especially ultrasound) and pulmonary function and phrenic nerve stimulation tests...
November 30, 2018: Pulmonology
Amanda Piper, Chung-Ming Chu
No abstract text is available yet for this article.
December 3, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
Zhifeng Liu, Qingyu Liu, Gongfa Wu, Haigang Li, Yue Wang, Rui Chen, Cai Wen, Qin Ling, Zhengfei Yang, Wanchun Tang
Background: Utilize quantitative computed tomography (QCT) to detect and evaluate the severity of lung injury after successful cardiopulmonary resuscitation (CPR) in a porcine cardiac arrest (CA) model with different downtimes. Methods: Twenty-one male domestic pigs weighing 38±3 kg were randomized into 3 groups: the sham group (n=5), the ventricular fibrillation (VF) 5 min (VF5) group (n=8), and the VF 10 min (VF10) group (n=8). VF was induced and untreated for 5 (VF5 group) or 10 (VF10 group) min before the commencement of manual CPR...
October 2018: Quantitative Imaging in Medicine and Surgery
Eduardo Borsini, Magalí Blanco, Glenda Ernst, Romina Ursino, Gabriela Robaina, Alejandro Salvado
Home mechanical ventilation represents a standard of care in the insufficiency of the ventilatory pump. The follow-up model could change the hospitalization rate. In order to study hospitalizations in patients with home mechanical ventilation, a descriptive study was designed on a systematic collection database. Participants were patients with non-invasive ventilation or invasive mechanical ventilation consecutively included in a day hospital program between July 2014 and December 2016. Hospitalizations and their modality one year before and after the program were analyzed...
2018: Medicina
Olga Archangelidi, Siobhán B Carr, Nicholas J Simmonds, Diana Bilton, Winston Banya, Paul Cullinan
BACKGROUND: Non-invasive ventilation (NIV) for respiratory failure and airway clearance is an established intervention in cystic fibrosis (CF), but its therapeutic benefit on lung function and survival remains under-investigated. METHODS: Using data from the UK CF Registry between 2007 and 2015, we explored the patterns of NIV use, and assessed changes in mean percent predicted FEV1 (ppFEV1 ) prior to and after NIV use, and the survival of patients on NIV. RESULTS: Among 11,079 patients, 1107 had at least one record of NIV treatment...
November 28, 2018: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
Sietske van der Leest, Marieke L Duiverman
Patients with end-stage chronic obstructive pulmonary disease (COPD) frequently develop chronic hypercapnic respiratory failure (CHRF), with disabling symptoms and poor survival. The use of long-term nocturnal non-invasive ventilation (NIV) to treat CHRF in COPD has long been subject of debate due to conflicting evidence. However, since the introduction of high-intensity NIV (HI-NIV) in COPD, physiological and clinical benefits have been shown. HI-NIV refers to specific ventilator settings used for NIV aimed at achieving normocapnia or the lowest partial arterial carbon dioxide pressure (PaCO2 ) values as possible...
November 30, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
Milena Tana, Alessandra Lio, Chiara Tirone, Claudia Aurilia, Eloisa Tiberi, Francesca Serrao, Velia Purcaro, Mirta Corsello, Piero Catenazzi, Vito D'Andrea, Giovanni Barone, Cinzia Ricci, Roberta Pastorino, Giovanni Vento
Objective: To evaluate if weaning from high-frequency oscillatory ventilation (HFOV) directly to a non-invasive mode of respiratory support is feasible and results in successful extubation in extremely low birth weight (ELBW) infants. Design: Prospective observational study. Setting: Tertiary neonatal intensive care unit. Patients: One hundred and eight ELBW infants of 26.2±1.4 weeks of gestational age (GA) directly extubated from HFOV...
2018: BMJ paediatrics open
Nicholas S West, Michael J Parkes, Christopher Snowden, James Prentis, Jill McKenna, Muhammad Shahid Iqbal, Christopher Walker
PURPOSE: Reducing respiratory motion during the delivery of radiotherapy reduces the volume of healthy tissues irradiated and may decrease radiation induced toxicity. The purpose of this study was to assess the potential for rapid shallow non-invasive mechanical ventilation to reduce internal anatomy motion for radiotherapy purposes. MATERIAL AND METHODS: Ten healthy volunteers (age 22-54years; mean 38years; 6 female and 4 male) were scanned on an MR scanner during normal breathing and at 2 ventilator induced frequencies; 20 and 25 breaths per minute for 3 minutes...
November 26, 2018: International Journal of Radiation Oncology, Biology, Physics
Farshid R Bashar, Amir Vahedian-Azimi, Behrooz Farzanegan, Reza Goharani, Seyedpouzhia Shojaei, Sevak Hatamian, Seyed M M Mosavinasab, Masoum Khoshfetrat, Mohammad A K Khatir, Anna Tomdio, Andrew C Miller
OBJECTIVE: To determine if non-invasive oxygenation indices, namely peripheral capillary oxygen saturation (Sp O2 )/fraction of inspired oxygen (Fi O2 ) and partial pressure of alveolar oxygen (PA O2 )/Fi O2 may be used as effective surrogates for the partial pressure of arterial oxygen (Pa O2 )/Fi O2 . Also, to determine the Sp O2 /Fi O2 and PA O2 /Fi O2 values that correspond to Pa O2 /Fi O2 thresholds for identifying acute respiratory distress syndrome (ARDS) in patients following coronary artery bypass graft (CABG) surgery...
November 27, 2018: Journal of Cardiothoracic Surgery
Zeyad Aljeboori, Alexandra Gorelik, Emily Jenkins, Thomas McFarlane, Jai Darvall
OBJECTIVES: There is an increasing incidence of invasive candidal infections in critically ill patients worldwide, which has prompted development of various risk prediction rules, both clinical and microbiological. To date, however, there is a lack of research into how cumulative risk factors over time affect transition to candidaemia. The aim of this study was to investigate the association of risk factor accumulation over time with candidaemia in a cohort of critically ill, non-neutropenic adult patients...
December 2018: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
Fulsen Bozkuş, Bora Bilal, Hafize Öksüz
Introduction: Ventilation treatment has proven success in acute respiratory distress syndrome (ARDS), while it still remains a challenge to utilize it with lower tidal volumes especially in subjects with respiratory acidosis. The concept of supporting conventional ventilation with extracorporeal carbondioxide removal (ECCO2R) may contribute in adjusting respiratory acidosis consequent to tidal volume reduction in protective ventilation setting. This method allows an easier management of ARDS due to its less invasive approach...
September 2018: Tüberküloz Ve Toraks
Josef Finsterer
Metabolic myopathies are a heterogeneous group of disorders characterized by inherited defects of enzymatic pathways involved in muscle fiber energetics. Diagnosing metabolic myopathies requires a thoroughly taken individual and family history, a meticulous neurologic exam, exercise tests, blood and urine tests, needle-electromyography, nerve-conduction studies, muscle biopsy, targeted genetic tests, or next-generation sequencing. There is limited evidence from the literature to guide treatment of metabolic myopathies...
December 2018: Expert Review of Neurotherapeutics
Pascaline M Alix, Flora Brunner, Anne Jolivot, Muriel Doret, Laurent Juillard
Pregnancy in women with end-stage renal disease is rare. Multiple pregnancies carry a high risk of complications even in healthy individuals. We report the case of a 36-year-old woman who had four pregnancies while she was on dialysis, including one twin pregnancy. The last pregnancy occurred while in the 14th year of hemodialysis. At 8 weeks of gestation (WG), ultrasonography diagnosed a dichorionic diamniotic twin pregnancy. The frequency of dialysis was increased from 3 to 6 times a week and each session lasted 4 h...
November 26, 2018: Journal of Nephrology
Davinia E Withington, Razaz Mujallid, Zainab Al Sabaa
BACKGROUND/AIMS: As little as 30 minutes of exposure to anesthetic and sedative agents may adversely affect the developing brain. Safe, humane management of critically ill infants requires the use of sedative agents, often for prolonged periods. We sought to identify two comparable groups of critical care patients who did or did not receive sedatives, with the aim of designing a long-term neuro-development follow-up study. This feasibility study aimed to determine if two comparable groups could be found...
November 25, 2018: Paediatric Anaesthesia
Mark W Elliott
Audits and case reviews of the acute delivery of non-invasive ventilation (NIV) have shown that the results achieved in real life often fall short of those achieved in research trials. Factors include inappropriate selection of patients for NIV and failure to apply NIV correctly. This highlights the need for proper training of all involved individuals. This article addresses the different skills needed in a team to provide an effective NIV service. Some detail is given in each of the key areas but it is not comprehensive and should stimulate further learning (reading, attendance on courses, e-learning, etc...
November 23, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
Leonardo Nava-Guerra, Bradley A Edwards, Philip I Terrill, Scott A Sands, Raouf S Amin, James S Kemp, Michael C K Khoo
RATIONALE: Ventilatory control instability is an important factor contributing to the pathogenesis of periodic breathing (PB) and other forms of sleep-related breathing disorders (SRBD). The development of tools for the quantification of such instabilities from non-invasive respiratory measurements during sleep could be useful to clinicians in identifying subjects that are at risk of developing SRBD. OBJECTIVES: To present and compare two different mathematical modeling approaches that allow the quantification of ventilatory control stability from the ventilatory responses to spontaneous sighs...
November 22, 2018: Physiological Measurement
Christian Karagiannidis, Stephan Strassmann, Jens Callegari, Matthias Kochanek, Uwe Janssens, Wolfram Windisch
BACKGROUND:  Home mechanical ventilation is dramatically evolving in Germany. Patients with non-invasive and invasive ventilation are increasingly treated at home. In-hospital treatment of these patients is also necessary either for control visits or the management of acute medical problems. However, the development of in-hospital patient care, morbidity and mortality of these patients is unknown. METHODS:  All patients with long-term dependence on mechanical ventilation for more than three months requiring hospitalisation between 2006 and 2016 were analysed (data obtained from the Federal Statistical Office of Germany)...
November 21, 2018: Deutsche Medizinische Wochenschrift
M Wirth, A Naud, G Caputo, J M Hascoët
AIM: We evaluated the weight, insulin-like growth factor-1, neonatal, retinopathy of prematurity (WINROP) algorithm for very premature infants. METHOD: Infants born before 32 weeks who had undergone fundus examinations in the neonatal intensive care unit at the University Hospital of Nancy were included in this French retrospective cohort study from July 2012 to July 2016. We evaluated how well the WINROP software predicted threshold retinopathy of prematurity (ROP)...
November 21, 2018: Acta Paediatrica
Michelle Tsao, Angelica A Vargas, John Hajduk, Renee Singh, Narasimhan Jagannathan
Structural and physiologic differences between a pediatric and an adult patient can make management of the pediatric airway a challenge. The majority of initial designs for airway devices were modeled for adult patients and simply downsized for the pediatric population. This paper reviews the last decade's design improvements in video laryngoscopes and supraglottic airway devices, as well as advances in the development of non-invasive oxygenation/ventilation techniques for pediatric airway management. Areas covered: Topic areas reviewed include basic principles of common and newer devices for video laryngoscopy, supraglottic airway management, and alternate ventilation techniques...
November 19, 2018: Expert Review of Medical Devices
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