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Non invasive ventilation ventilators

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https://www.readbyqxmd.com/read/30326162/interventions-for-preventing-and-treating-cardiac-complications-in-duchenne-and-becker-muscular-dystrophy-and-x-linked-dilated-cardiomyopathy
#1
REVIEW
John P Bourke, Teofila Bueser, Rosaline Quinlivan
BACKGROUND: The dystrophinopathies include Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), and X-linked dilated cardiomyopathy (XLDCM). In recent years, co-ordinated multidisciplinary management for these diseases has improved the quality of care, with early corticosteroid use prolonging independent ambulation, and the routine use of non-invasive ventilation signficantly increasing survival. The next target to improve outcomes is optimising treatments to delay the onset or slow the progression of cardiac involvement and so prolong survival further...
October 16, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/30322437/current-statement-of-intensive-care-units-in-turkey-data-obtained-from-67-centers
#2
Özlem Ediboğlu, Özlem Yazıcıoğlu Moçin, Ezgi Özyılmaz, Cüneyt Saltürk, Tuğba Önalan, Gülşah Seydaoğlu, Turgay Çelikel, Hüseyin Arıkan, Sena Ataman, Cenk Kıraklı, Zerrin Özçelik, Sema Kultufan, İskender Kara, Atilla Kara, Emine Dağlı, Selma Duru Bülbül, Kadriye Kahveci, Metin Dinçer, Nimet Şenoğlu, Hüseyin Özkarakaş, İlhan Bahar, Melike Cengiz, Atilla Ramazanoğlu, Burcu Çelik, Ümmügülsün Gaygısız, Gülay Kır, Ahmet Bindal, Belgin Akan, Işıl Özkoçak Turan, Fatma Yıldırım, Burcu Başarık, Zeliha Arslan Ulukan, Serdar Efe, Murat Sungur, Şahin Temel, Seval İzdeş, Derya Hoşgün, Nurhan Karadeniz, Eylem Tuncay, Nezihe Çiftarslan Gökşenoğlu, İlim Irmak, Utku Datlı, Avşar Zerman, Devrim Akdağ, Levent Özdemir, Gülseren Elay, Yücel Karaçayır, Arzu Topeli, Pervin Hancı, Esat Kıvanç Kaya, Pınar Güven, Hilal Sazak, Semih Aydemir, Gülbin Aygencel, Yusuf Aydemir, Zahide Doğanay, Özgür Kömürcü, Volkan Hancı, Emre Karakoç, Didem Sözütek, Güven Coşkun, Güngör Ateş, Civan Tiryaki, Ayşe Nur Soytürk, Nermin Kelebek Girgin, Gülbahar Çalışkan, Oben Bıyıklı, Necati Gökmen, Uğur Koca, Aydın Çiledağ, Kezban Özmen Süner, İsmail Cinel, Mustafa Kemal Arslantaş, Fethi Gül, Recai Ergün, Nafiye Yılmaz, Defne Altıntaş, Leyla Talan, Murat Yalçınsoy, Mehmet Nezir Güllü, Perihan Ergin Özcan, Günseli Orhun, Yusuf Savran, Murat Emre Tokur, Serdar Akpınar, Pelin Şen, Gül Gürsel, İrem Şerifoğlu, Ender Gedik, Öner Abidin Balbay, Türkay Akbaş, Sinem Cesur, Hülya Yolacan, Seda Beyhan Sağmen, Pervin Korkmaz Ekren, Feza Bacakoğlu, Begüm Ergan, Ersin Günay, Muzaffer Sarıaydın, Dursun Ali Sağlam, Sait Karakurt, Emel Eryüksel, Funda Öztuna, Emine Sevil Ayaydın Mürtezaoğlu, Hakan Cinemre, Ahmet Nalbant, Öznur Yağmurkaya, Tuğba Mandal, Belgin İkidağ
OBJECTIVES: We aimed to obtain information about the characteristics of the ICUs in our country via a point prevalence study. MATERIAL AND METHODS: This cross-sectional study was planned by the Respiratory Failure and Intensive Care Assembly of Turkish Thoracic Society. A questionnaire was prepared and invitations were sent from the association's communication channels to reach the whole country. Data were collected through all participating intensivists between the October 26, 2016 at 08:00 and October 27, 2016 at 08:00...
September 13, 2018: Turkish Thoracic Journal
https://www.readbyqxmd.com/read/30321833/high-flow-nasal-therapy-vs-standard-oxygen-during-breaks-off-noninvasive-ventilation-for-acute-respiratory-failure-a-pilot-randomized-controlled-trial
#3
Giulia Spoletini, Chiara Mega, Lara Pisani, Mona Alotaibi, Alia Khoja, Lori Lyn Price, Francesco Blasi, Stefano Nava, Nicholas S Hill
PURPOSE: To assess the role of high-flow nasal therapy (HFNT) compared to standard oxygen (SO) as complementary therapy to non-invasive ventilation (NIV). METHODS: Multicenter trial including patients (n = 54) anticipated to receive NIV for ≥24 h due to acute or acute-on-chronic respiratory failure. Subjects were randomized (1:1) to SO or HFNT during breaks off NIV. Primary outcome was total time on and off NIV. Secondary outcomes were comfort and dyspnea, respiratory rate (RR), oxygen saturation (Sp O2 ), tolerance and side effects...
October 5, 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/30321228/epidemiology-clinical-presentation-and-respiratory-sequelae-of-adenovirus-pneumonia-in-children-in-kuala-lumpur-malaysia
#4
Li Min Lim, Yen Yen Woo, Jessie Anne de Bruyne, Anna Marie Nathan, Sze Ying Kee, Yoke Fun Chan, Chun Wei Chiam, Kah Peng Eg, Surendran Thavagnanam, I-Ching Sam
OBJECTIVES: To describe the severity, human adenovirus (HAdV) type and respiratory morbidity following adenovirus pneumonia in children. METHODOLOGY: Retrospective review of children under 12 years of age, admitted with HAdV pneumonia, between January 2011 and July 2013, in a single centre in Malaysia. HAdV isolated from nasopharyngeal secretions were typed by sequencing hypervariable regions 1-6 of the hexon gene. Patients were reviewed for respiratory complications...
2018: PloS One
https://www.readbyqxmd.com/read/30310018/-mechanical-ventilation
#5
Masayoshi Inoue
Mechanical ventilation is a useful treatment option for respiratory insufficiency following thoracic and cardiovascular surgery. Ventilation mode is classified as volume-controlled-ventilation(VCV) and pressure-controlled ventilation(PCV). Non-invasive ventilation(NIV) without tracheal intubation has been recently developed and is effective in patients with chronic obstructive pulmonary disease (COPD) exacerbation. Several pulmonary complications by mechanical ventilation such as ventilator-induced lung injury(VILI) or ventilator-associated pneumonia(VAP) could be avoided with NIV...
September 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/30306285/the-diagnostic-yield-safety-and-impact-of-flexible-bronchoscopy-in-non-hiv-immunocompromised-critically-ill-patients-in-the-intensive-care-unit
#6
Mazen O Al-Qadi, Rodrigo Cartin-Ceba, Rahul Kashyap, Sumanjit Kaur, Steve G Peters
BACKGROUND: Flexible bronchoscopy (FB) and bronchoalveolar lavage (BAL) have major roles in the evaluation of parenchymal lung diseases in immunocompromised patients. Given the limited evidence, lack of standardized practice, and variable perception of procedural safety, uncertainty still exists on what constitutes the best approach in critically ill patients with immunocompromised state who present with pulmonary infiltrates in the era of prophylactic antimicrobials and the presence of new diagnostic tests...
October 10, 2018: Lung
https://www.readbyqxmd.com/read/30304909/transient-intubation-for-surfactant-administration-in-the-treatment-of-respiratory-distress-syndrome-in-extremely-premature-infants
#7
Ji Won Koh, Jong-Wan Kim, Young Pyo Chang
Purpose: To investigate the effectiveness of transient intubation for surfactant administration and extubated to nasal continuous positive pressure (INSURE) for treatment of respiratory distress syndrome (RDS) and to identify the factors associated with INSURE failure in extremely premature infants. Methods: Eighty-four infants with gestational age less than 28 weeks treated with surfactant administration for RDS for 8 years were included. Perinatal and neonatal characteristics were retrospectively reviewed, and major pulmonary outcomes such as duration of mechanical ventilation (MV) and bronchopulmonary dysplasia (BPD) plus death at 36 weeks postmenstrual age (PMA) were compared between INSURE (n=48) and prolonged MV groups (n=36)...
September 16, 2018: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/30302247/management-of-severe-acute-exacerbations-of-copd-an-updated-narrative-review
#8
REVIEW
Ernesto Crisafulli, Enric Barbeta, Antonella Ielpo, Antoni Torres
Background: Patients with chronic obstructive pulmonary disease (COPD) may experience an acute worsening of respiratory symptoms that results in additional therapy; this event is defined as a COPD exacerbation (AECOPD). Hospitalization for AECOPD is accompanied by a rapid decline in health status with a high risk of mortality or other negative outcomes such as need for endotracheal intubation or intensive care unit (ICU) admission. Treatments for AECOPD aim to minimize the negative impact of the current exacerbation and to prevent subsequent events, such as relapse or readmission to hospital...
2018: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/30296878/treatment-transport-and-primary-care-involvement-when-helicopter-emergency-medical-services-are-inaccessible-a-retrospective-study
#9
Dag Ståle Nystøyl, Steinar Hunskaar, Hans Johan Breidablik, Øyvind Østerås, Erik Zakariassen
OBJECTIVE: To examine handling of cancelled helicopter emergency medical services (HEMS) missions with a persisting medical indication. DESIGN: Retrospective observational study. SETTING AND SUBJECTS: Cancelled HEMS missions with persisting medical indication within Sogn og Fjordane county in Norway during the period of 2010-2013. Both primary and secondary missions were included. MAIN OUTCOME MEASURES: Primary care involvement, treatment and cooperation within the prehospital system...
October 8, 2018: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/30290642/a-case-report-of-legionella-and-mycoplasma-pneumonia-co-incidence-or-co-infection
#10
Lakshmi Saladi, Bushra Zaidi, Omesh Toolsie, Trupti Vakde, Muhammad Adrish
RATIONALE: Concurrent or sequential coinfections of Legionella pneumophila and Mycoplasma pneumoniae have been reported in the past though infrequently. Distinguishing a true co-infection from cross reactivity is often challenging as the diagnosis is mostly dependent on serological testing. PATIENT CONCERNS: A 77-year-old male presented with worsening dyspnea, cough with yellow sputum, diarrhea and fever of 2-days duration. Patient had history of chronic obstructive pulmonary disease (COPD) on home oxygen, bronchiectasis, rheumatoid arthritis (on methotrexate and leflunomide), treated pulmonary tuberculosis and 30-pack-year smoking...
October 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30290021/evidence-based-clinical-guidelines-on-analgesia-and-sedation-in-newborn-infants-undergoing-assisted-ventilation-and-endotracheal-intubation
#11
REVIEW
Gina Ancora, Paola Lago, Elisabetta Garetti, Daniele Merazzi, Patrizia Savant Levet, Carlo Valerio Bellieni, Luisa Pieragostini, Anna Pirelli
AIM: This review informed pain control guidelines for clinicians performing mechanical ventilation, nasal continuous positive airway pressure and endotracheal intubation on term and preterm newborn infants. METHODS: We reviewed literature published between 1986 and June 2017 on analgesia and sedation during assisted ventilation and before endotracheal intubation in newborn infants admitted to neonatal intensive care units. The subsequent guidelines were developed using the Grading of Recommendations Assessment, Development and Evaluation approach...
October 5, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/30279867/primary-cardiac-myc-bcl6-double-hit-non-hodgkin-lymphoma
#12
Ombretta Annibali, Antonio Nenna, Raffaele Barbato, Massimo Chello, Pietro Sedati, Antonella Bianchi, Giuseppe Deda, Giuseppe Avvisati
Cardiac and pericardial involvement by malignant lymphoma is a rare condition. The present case report describes a case of primary cardiac MYC/BCL6 double hit non-Hodgkin lymphoma in the pericardium, and highlights the importance of a prompt diagnosis and aggressive pharmacologic treatment of this disease. In a symptomatic patient, a minimally invasive 3 cm sub-xiphoidal incision was performed under deep sedation with spontaneous ventilation to perform a pericardial biopsy. A 5 cm × 3 cm portion of pericardium was removed from above the right ventricle, thus ameliorating the extrinsic compression on the right chambers...
March 2018: Journal of Cardiology Cases
https://www.readbyqxmd.com/read/30278498/treatment-outcomes-of-patients-with-non-bacteremic-pneumonia-caused-by-extensively-drug-resistant-acinetobacter-calcoaceticus-acinetobacter-baumannii-complex-isolates-is-there-any-benefit-of-adding-tigecycline-to-aerosolized-colistimethate-sodium
#13
Shio-Shin Jean, Tai-Chin Hsieh, Wen-Sen Lee, Po-Ren Hsueh, Chin-Wan Hsu, Carlos Lam
Few therapeutic options exist for various infections caused by extensively drug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii (XDR-Acb) complex isolates, including pneumonia. This study investigated the clinical efficacy between aerosolized colistimethate sodium (AS-CMS, 2 million units thrice a day) treatment alone or in combination with standard-dose tigecycline (TGC) in patients with non-bacteremic pneumonia due to XDR-Acb, and explored the factors influencing patients' 30-day mortality.A 1:1 case (n = 106; receiving TGC plus AS-CMS) control (receiving AS-CMS alone with matching scores) observational study was conducted among adult patients with non-bacteremic XDR-Acb complex pneumonia in a Taiwanese medical center from January 2014 through December 2016...
September 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30267802/herpes-simplex-virus-hsv-pneumonia-in-the-non-ventilated-immunocompromised-host-burden-and-predictors
#14
Luzzati Roberto, D'Agaro Pierlanfranco, Busca Annalisa, Maurel Cristina, Martellani Fulvia, Rosin Chiara, Segat Ludovica, Gatti Giuseppe, Mascarello Marta, Confalonieri Marco
OBJECTIVES: To evaluate burden and predictors of HSV pneumonia among immunocompromised patients not undergoing invasive mechanical ventilation according to a tailored diagnostic algorithm. METHODS: This prospective, observational study included immunocompromised adults with pneumonia non-responding to empirical antibiotic therapy. Bronchoalveolar lavage (BAL) specimens were cultured for bacteria, mycobacteria and fungi. Real-time PCR for Herpesviruses and other microorganisms were performed on BAL and other specimens...
September 26, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30265147/very-late-onset-amyotrophic-lateral-sclerosis-in-a-portuguese-cohort
#15
Miguel Oliveira Santos, Marta Gromicho, Susana Pinto, Mamede de Carvalho
OBJECTIVE: Although amyotrophic lateral sclerosis (ALS) incidence has been stable among Western countries, population-ageing effect will probably increase the proportion of very-old ALS patients. We aim to study this population. METHODS: A retrospective study was performed, including 1083 ALS patients followed longitudinally in our ALS unit from January 1995 to December 2017. The patients were divided in two groups, according to age at disease onset (</≥80 years)...
September 28, 2018: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/30263856/building-on-the-shoulders-of-giants-is-the-use-of-early-spontaneous-ventilation-in-the-setting-of-severe-diffuse-acute-respiratory-distress-syndrome-actually-heretical
#16
REVIEW
Fabrice Petitjeans, Cyrille Pichot, Marco Ghignone, Luc Quintin
Acute respiratory distress syndrome (ARDS) is not a failure of the neurological command of the ventilatory muscles or of the ventilatory muscles; it is an oxygenation defect. As positive pressure ventilation impedes the cardiac function, paralysis under general anaesthesia and controlled mandatory ventilation should be restricted to the interval needed to control the acute cardio-ventilatory distress observed upon admission into the critical care unit (CCU; "salvage therapy" during "shock state")...
September 2018: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/30263122/salivary-biomarkers-may-measure-stress-responses-in-critically-ill-children
#17
Despoina Tzira, Anargyroula Prezerakou, Ioannis Papadatos, Artemis Vintila, Anastasia Bartzeliotou, Filia Apostolakou, Ioannis Papassotiriou, Vassiliki Papaevangelou
Objective: Measurement of salivary biomarkers can provide important information regarding hypothalamic-pituitary-adrenal axis activity both under normal conditions as well as in response to psychological or physical stress. Our aim was to correlate salivary stress markers, such as cortisol, α-amylase and immunoglobulin A, with the Pediatric Risk Index Score of Mortality, underlying disease (pathologic, trauma and postoperative), need for mechanical ventilation/sedation and time lag between onset of illness and admission in children admitted in the pediatric intensive care unit...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/30263094/oxygenation-non-invasive-ventilation-strategy-and-risk-for-intubation-in-immunocompromised-patients-with-hypoxemic-acute-respiratory-failure
#18
Guillaume Dumas, Sylvie Chevret, Virginie Lemiale, Frédéric Pène, Alexandre Demoule, Julien Mayaux, Achille Kouatchet, Martine Nyunga, Pierre Perez, Laurent Argaud, François Barbier, François Vincent, Fabrice Bruneel, Kada Klouche, Loay Kontar, Anne-Sophie Moreau, Jean Reignier, Laurent Papazian, Yves Cohen, Djamel Mokart, Elie Azoulay
We investigated how the initial ventilation/oxygenation management may influence the need for intubation on the coming day in a cohort of immunocompromised patients with acute hypoxemic respiratory failure (ARF). Data from 847 immunocompromised patients with ARF were used to estimate the probability of intubation at day+1 within the first 3 days of ICU admission, according to oxygenation management. First, noninvasive ventilation (NIV) was compared to oxygen therapy whatever the administration device; then standard oxygen was compared to High Flow Nasal Cannula therapy alone (HFNC), NIV alone or NIV+HFNC...
September 14, 2018: Oncotarget
https://www.readbyqxmd.com/read/30262577/development-and-validation-of-a-simple-tool-for-the-assessment-of-home-niv-the-s-3-niv-questionnaire
#19
Elise Dupuis-Lozeron, Grégoire Gex, Patrick Pasquina, Pierre-Olivier Bridevaux, Jean-Christian Borel, Paola Gasche-Soccal, Wolfram Windisch, Jean-Louis Pépin, Jean-Paul Janssens, Dan Adler
Patient-centered outcomes are significantly modified by long-term home non-invasive ventilation (NIV), but a short, self-administered, specific tool for routine clinical assessment is lacking. The aim of this study was to develop and validate the S3 -NIV questionnaire, a short questionnaire to measure respiratory <u>s</u> ymptoms, <u>s</u> leep quality and NIV-related <u>s</u> ide-effects.Stable patients under long-term home NIV were recruited from three outpatient NIV services...
September 27, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/30251225/validation-of-new-marker-of-fluid-responsiveness-based-on-doppler-assessment-of-blood-flow-velocity-in-superior-vena-cava-in-mechanically-ventilated-pigs
#20
Tomas Kovarnik, Miroslav Navratil, Jan Belohlavek, Mikulas Mlcek, Martin Chval, Zhi Chen, Stepan Jerabek, Otomar Kittnar, Ales Linhart
BACKGROUND: We studied a novel approach for the evaluation and management of volemia: minimally invasive monitoring of respiratory blood flow variations in the superior vena cava (SVC). We performed an experiment with 10 crossbred (Landrace × large white) female pigs (Sus scrofa domestica). METHODS: Hypovolemia was induced by bleeding from a femoral artery, in six stages. This was followed by blood return and then an infusion of 1000 ml saline, resulting in hypervolemia...
September 24, 2018: Intensive Care Medicine Experimental
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