keyword
https://read.qxmd.com/read/38531046/experience-with-laparoscopic-and-robotic-colon-surgery-together-with-other-major-minimally-invasive-procedures-for-unrelated-pathologies
#21
JOURNAL ARTICLE
Hugo J R Bonatti
Background: Indications for combined colon surgery together with other procedures include oncologic multivisceral resections and abdominal trauma. It is unclear if combining minimally invasive (MI) colon surgery with unrelated other procedures increases the risk for complications. Patients and Methods: The surgical database from two institutions during a 10-year period was queried for combined colon surgeries together with other interventions. All open cases, combined cases performed for one pathology and MI colectomies together with a minor procedure, were excluded...
March 27, 2024: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://read.qxmd.com/read/38530105/prevalence-and-predictors-of-colon-and-prostate-cancer-screening-among-volunteer-firefighters-the-united-states-firefighter-cancer-assessment-and-prevention-study
#22
JOURNAL ARTICLE
Nimit N Shah, Michael B Steinberg, Miriam M Calkins, Alberto J Caban-Martinez, Jefferey L Burgess, Elena Austin, Brittany S Hollerbach, Derrick L Edwards, Taylor M Black, Kathleen Black, Kaleigh M Hinton, Brian S Kubiel, Judith M Graber
BACKGROUND: Although firefighters have increased risk for colon and prostate cancer, limited information exists on screening practices for these cancers in volunteer firefighters who compose two-thirds of the US fire service. We estimated the prevalence of colon and prostate cancer screening among volunteer firefighters using eligibility criteria from 4 evidence-based screening recommendations and evaluated factors influencing screening. METHODS: We evaluated colon (n = 569) and prostate (n = 498) cancer screening prevalence in a sample of US volunteer firefighters using eligibility criteria from the US Preventive Services Taskforce (USPSTF), National Fire Protection Association, American Cancer Society, and National Comprehensive Cancer Network...
March 26, 2024: American Journal of Industrial Medicine
https://read.qxmd.com/read/38529850/right-sided-colonic-diverticulitis-short-and-long-term-surgical-outcomes-and-2-year-quality-of-life
#23
JOURNAL ARTICLE
Sara Lauricella, Francesco Brucchi, Dario Palmisano, Gianandrea Baldazzi, Luca Bottero, Diletta Cassini, Giuseppe Faillace
AIM: We aimed to investigate the short and the long-term outcomes and 2-year Quality of Life (QoL) of patients with right-sided colonic diverticulitis (RCD) surgically managed. METHOD: We conducted an ambidirectional cohort study of patients with RCD undergoing surgery between 2012/2022. A colonoscopy was performed at 1-year post surgery. The enrolled patients completed the EuroQoL (EQ-5D-3L) during a regular follow-up visit at 12 and 24 months after surgery...
February 2024: World Journal of Surgery
https://read.qxmd.com/read/38529438/unveiling-the-enigma-of-a-colonic-neuroendocrine-tumor-causing-ileocolic-intussusception-a-case-report
#24
Natalie Mesa, Lizis O Rodriguez, Mitchel Lacey, Rupa Seetharamaiah
Intussusception in adults is rare and is often associated with a pathologic lead point. While colonic adenocarcinoma is a common cause, well-differentiated colonic neuroendocrine tumors are exceedingly rare. We present a unique case of an ileocolic intussusception due to a distal ascending colonic neuroendocrine tumor, emphasizing the diagnostic challenges and importance of prompt intervention. A 60-year-old male with a previous screening colonoscopy in June of 2022 presented to the Emergency Department with two days of cramping, right upper abdominal pain with associated nausea and two episodes of emesis...
February 2024: Curēus
https://read.qxmd.com/read/38528786/genistein-enhances-trail-mediated-apoptosis-through-the-inhibition-of-xiap-and-dcr1-in-colon-carcinoma-cells-treated-with-5-fluorouracil
#25
JOURNAL ARTICLE
Tuğbagül Çal Doğan, Sevtap Aydın Dilsiz, Hande Canpınar, Ülkü Ündeğer Bucurgat
OBJECTIVES: Colorectal cancer is one of the most common cancers worldwide. However, surgical intervention and chemotherapy provide only limited benefits for the recovery and survival of patients. The anticarcinogenic effect of genistein has attracted attention because epidemiological studies have shown that soybean consumption is associated with a decrease in the incidence of cancer. There are limited studies on the effects of genistein in colorectal carcinoma cells. We aimed to investigate the cytotoxic, genotoxic, and apoptotic effects of genistein in SW480 and SW620 colon adenocarcinoma cells treated with 5-fluorouracil, the basis of chemotherapy, and the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) ligand, the mediator of apoptosis, both alone and in combination...
March 25, 2024: Turkish journal of pharmaceutical sciences
https://read.qxmd.com/read/38528113/a-randomized-controlled-study-to-assess-the-effect-of-mosapride-citrate-on-intestinal-recovery-following-gastrectomy
#26
RANDOMIZED CONTROLLED TRIAL
Shiyeol Jun, Seyeol Oh, Ji Eun Jung, In Gyu Kwon, Sung Hoon Noh
The enhanced recovery after surgery (ERAS) protocol, including prokinetic medications, is commonly used to prevent postoperative ileus. Prospective studies evaluating the effectiveness of mosapride citrate, a prokinetic 5-hydroxytryptamine 4 receptor agonist, in patients undergoing gastrectomy within the ERAS framework are lacking. This double-blind randomized trial included patients who were scheduled for laparoscopic or robotic gastrectomy for gastric cancer. Participants were randomly assigned to either a control (placebo) or experimental (mosapride citrate) group, with drugs administered on postoperative days 1-5...
March 25, 2024: Scientific Reports
https://read.qxmd.com/read/38527938/safety-and-feasibility-of-colonoscopy-in-nonagenarians-a-systematic-review-meta-analysis-and-meta-regression-analysis
#27
REVIEW
Shahab Hajibandeh, Shahin Hajibandeh, Azel Regan, Jennifer Waterman, Christopher M B Stewart, James Ansell, James Horwood, Simon Phillips, Michael Davies
AIM: The aim of this work was to evaluate the safety and feasibility of performing colonoscopy in patients aged 90 years or over. METHOD: In compliance with PRISMA statement standards, a systematic review of studies reporting the outcomes of colonoscopy in patients aged ≥90 years was conducted. A proportional meta-analysis model was constructed to quantify the risk of outcomes and a direct comparison meta-analysis model was constructed to compare outcomes between nonagenarians and patients aged between 50 and 89 years via random-effects models...
March 25, 2024: Colorectal Disease
https://read.qxmd.com/read/38527929/perioperative-outcomes-of-ileorectal-anastomosis-an-analysis-of-823-patients
#28
JOURNAL ARTICLE
Adam Truong, Katherine Hu, David Liska, Michael Valente, Tracy Hull, Scott R Steele, Stefan D Holubar
AIM: Ileorectal anastomosis (IRA) following total abdominal colectomy (TAC) allows for resortation of bowel continuity but prior studies have reported rates of anastomotic leak (AL) to be as high as 23%. We aimed to report rates of AL and complications in a large cohort of patients undergoing IRA. We hypothesized that AL rates were lower than previously reported and that selective use of diverting loop ileostomy (DLI) is associated with decreased AL rates. METHOD: Patients undergoing TAC or end-ileostomy reversal with IRA, with or without DLI, between 1980 and 2021 were identified from a prospectively maintained institutional database and retrospectively analysed...
March 25, 2024: Colorectal Disease
https://read.qxmd.com/read/38526815/analysis-and-identification-of-phenolic-compounds-with-antiproliferative-activity-from-chinese-olive-canarium-album-l-fruit-extract-by-hplc-dad-spe-tt-nmr
#29
JOURNAL ARTICLE
Yu-Te Yeh, Chien-Kuang Chen, Yi-Chun Liao, Shoei-Sheng Lee, Shu-Chen Hsieh
Chinese olives (Canarium album L.) are rich in phenolic compounds, exhibiting a broad spectrum of potential clinical applications. This study is the first report on the isolation and elucidation of bioactive compounds with high antiproliferative activity from the ethyl acetate fraction of a Chinese olive fruit methanolic extract (CO-EtOAc). We used the WST-1 assay to determine which subfractions of CO-EtOAc had significant antiproliferative activity using the murine colon cancer cell line CT26. Subsequently, the functional compounds were characterized by the hyphenated technique and high-performance liquid chromatography-diode array detector-solid phase extraction-transfer tube-nuclear magnetic resonance (HPLC-DAD-SPE-TT-NMR)...
December 15, 2023: Journal of Food and Drug Analysis
https://read.qxmd.com/read/38526696/a-sice-societ%C3%A3-italiana-di-chirurgia-endoscopica-e-nuove-tecnologie-observational-prospective-multicenter-study-on-anatomical-variants-of-the-superior-mesenteric-artery-intraoperative-analysis-during-laparoscopic-right-hemicolectomy-codig-2-database-colondx
#30
JOURNAL ARTICLE
G Anania, A Campagnaro, M Chiozza, J Randolph, G Resta, S Marino, S Pedon, A Agrusa, D Cuccurullo, R Cirocchi
Colorectal cancer, the third most common cancer worldwide, affects 40-45% of patients on the right side. Surgery, especially minimally invasive methods such as laparoscopic and robotic procedures, is the preferred treatment. However, these techniques present technical complications. The anatomical complexity and variations in vessel branching patterns pose challenges, particularly for less experienced surgeons. The CoDIG 2 is a nationwide observational study involving 76 specialized Italian general surgery departments focused on colorectal surgery...
March 25, 2024: Updates in Surgery
https://read.qxmd.com/read/38525960/unveiling-the-hidden-consequences-the-initial-impact-of-covid-19-on-colorectal-cancer-operation
#31
JOURNAL ARTICLE
Davide Ferrari, Tommaso Violante, Courtney N Day, Nicholas P McKenna, Kellie L Mathis, Eric J Dozois, David W Larson
BACKGROUND: The COVID-19 pandemic has severely affected healthcare systems globally, resulting in significant delays and challenges in various medical treatments, particularly in cancer care. This study aims to investigate the repercussions of the pandemic on surgical interventions for colorectal cancer in the United States, using data from the National Cancer Database (NCDB). METHODS: We conducted a retrospective analysis of the NCDB, encompassing adult patients who underwent surgical procedures for colon and rectal cancer in 2019 (pre-COVID) and 2020 (COVID)...
March 25, 2024: Journal of the American College of Surgeons
https://read.qxmd.com/read/38525799/how-have-us-colorectal-cancer-mortality-trends-changed-in-the-past-20%C3%A2-years
#32
JOURNAL ARTICLE
Jia Yi Tan, Yong-Hao Yeo, Wern Lynn Ng, Zhi Ven Fong, Justin T Brady
In the last two decades, colorectal cancer (CRC) mortality has been decreasing in the United States. However, the mortality trends for the different subtypes of CRC, including different sides of colon, rectosigmoid, and rectal cancer remain unclear. We analyzed the mortality trends of different subtypes of CRC based on Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research data from 1999 to 2020. We calculated age-adjusted mortality rates (AAMR) per 100,000 individuals and examined the trends over time by estimating the average annual percent change (AAPC) using the Joinpoint Regression Program...
March 25, 2024: International Journal of Cancer. Journal International du Cancer
https://read.qxmd.com/read/38525722/an-assessment-of-knowledge-attitude-and-practice-kap-of-colorectal-cancer-among-community-pharmacists-in-the-qassim-region-of-saudi-arabia
#33
JOURNAL ARTICLE
Mohammed Alshammari, Saleh Al-Maktoum, Abdulrahman Alsharidah, Abubakar Siddique, Mohammed Anaam, Saud Alsahali, Yasser Almogbel, Ali Alkhoshaiban
Background : The global burden of colorectal cancer remains a major public health issue and one of the leading causes of death worldwide. In Saudi Arabia, it continues to be a health concern. Any delays in diagnosis for any reason may contribute to advanced complications; therefore, pharmacists' knowledge and awareness of colorectal cancer are crucial for the welfare of society. Studies of colon cancer-related knowledge, attitude, and practice (KAP) among community pharmacists have not previously been conducted in the Al-Qassim region of Saudi Arabia...
February 27, 2024: Pharmacy (Basel, Switzerland)
https://read.qxmd.com/read/38525292/cmnet-deep-learning-model-for-colon-polyp-segmentation-based-on-dual-branch-structure
#34
JOURNAL ARTICLE
Xuguang Cao, Kefeng Fan, Cun Xu, Huilin Ma, Kaijie Jiao
PURPOSE: Colon cancer is one of the top three diseases in gastrointestinal cancers, and colon polyps are an important trigger of colon cancer. Early diagnosis and removal of colon polyps can avoid the incidence of colon cancer. Currently, colon polyp removal surgery is mainly based on artificial-intelligence (AI) colonoscopy, supplemented by deep-learning technology to help doctors remove colon polyps. With the development of deep learning, the use of advanced AI technology to assist in medical diagnosis has become mainstream and can maximize the doctor's diagnostic time and help doctors to better formulate medical plans...
March 2024: Journal of Medical Imaging
https://read.qxmd.com/read/38524743/the-frequency-of-nras-mutation-in-stool-samples-of-iranian-colorectal-cancers-compared-to-finnish-patients
#35
JOURNAL ARTICLE
Farideh Saberi, Omar Youssef, Arto Kokkola, Mahsa Khodadoostan, Pauli Puolakkainen, Rasoul Salehi, Sakari Knuutila
BACKGROUND: Stools from colorectal cancer patients are noninvasive samples that could be used to compare the frequency of hotspot mutations between two different ethnic cohorts. MATERIALS AND METHODS: We collected stool samples from the Iranian cohort (52 patients and 49 controls) and the Finnish cohort (40 patients and 14 controls). Following stool DNA extraction, we used the AmpliSeq Colon and Lung Cancer panel to prepare DNA libraries before sequencing. RESULTS: The Iranian cohort exhibited 35 hotspot mutations in the BRAF , ERBB4 , FBXW7 , FGFR1 , FGFR3 , KRAS , MAP2K , MET , NRAS , PIK3C , SMAD4 , and TP53 genes...
2024: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://read.qxmd.com/read/38524662/utility-of-articulating-instruments-as-an-alternative-to-robotic-devices-in-laparoscopic-right-hemicolectomy
#36
JOURNAL ARTICLE
Yusuke Sakamoto, Yoshiro Itatani, Kazuhiro Nishiyama, Yusuke Fujita, Nobuaki Hoshino, Ryosuke Okamura, Tatsuto Nishigori, Shigeo Hisamori, Shigeru Tsunoda, Koya Hida, Kazutaka Obama
UNLABELLED: Laparoscopic complete mesocolic excision with central vessel ligation has been widely accepted for its oncological benefits in colon cancer surgery. However, laparoscopic right hemicolectomy involves a risk for vascular injury during dissection around the surgical trunk. This technical difficulty has been attributed to the limited movement of conventional laparoscopic forceps. Although robotic devices can overcome the restricted motion of laparoscopic devices, they are not yet widely used...
April 2024: International cancer conference journal
https://read.qxmd.com/read/38524654/giant-retroperitoneal-myolipoma-mimicking-liposarcoma-report-of-a-resected-case-and-review-of-the-literature
#37
JOURNAL ARTICLE
Kosuke Mori, Takamichi Igarashi, Akira Noguchi, Miki Ito, Yasuhiro Nagaoka, Chitaru Takeshita, Naoya Takeda, Toru Watanabe, Isaku Yoshioka, Kenichi Hirabayashi, Tsutomu Fujii
Myolipomas are rare tumors that are often difficult to differentiate from liposarcoma. Herein, we report a case of resected giant myolipoma preoperatively diagnosed as liposarcoma. A 63-year-old woman was suspected of having a large retroperitoneal liposarcoma on October 202X. The patient was referred to our department for tumor resection and a histological diagnosis. After consultation with the urology, obstetric and gynecology, and vascular surgery departments, tumor resection was planned, including the potential resection of other organs...
April 2024: International cancer conference journal
https://read.qxmd.com/read/38524649/intratumoral-metastasis-of-sigmoid-colon-cancer-to-chromophobe-renal-cell-carcinoma-a-case-report
#38
JOURNAL ARTICLE
Suzuna Sakai, Kojiro Ohba, Kazunari Migita, Ichiro Sekine, Yasuto Yamazaki
We herein report an extremely rare case of intratumoral metastasis of colon cancer to chromophobe renal cell carcinoma. A 71-year-old woman was diagnosed with lung metastasis of sigmoid colon cancer and underwent sigmoid colon resection with D3 lymph node dissection. Preoperative contrast-enhanced computed tomography (CT) revealed a left renal tumor; however, colon resection was prioritized, and the renal tumor was placed under observation. Two years later, CT revealed enlargement of the left renal tumor, and laparoscopic partial left nephrectomy was performed 1 month later...
April 2024: International cancer conference journal
https://read.qxmd.com/read/38524092/varicella-zoster-meningitis-and-myelitis-after-herpes-zoster-dermatitis-treatment-with-amenamevir-a-case-series-and-literature-review
#39
Satoru Tada, Yuta Kaito, Akihiro Watanabe, Yukio Sugiyama, Akira Nishigaichi, Takashi Miwa, Kotaro Watanabe, Takanori Hazama, Daisuke Takahashi
Varicella-zoster virus (VZV), known for causing chickenpox, establishes latent infections in neural tissues. Reactivation of VZV can lead to herpes zoster (HZ) and various neurological complications. In this report, we present four cases of VZV meningitis and myelitis following amenamevir treatment for HZ dermatitis with positive VZV DNA in cerebrospinal fluid (CSF) revealed by polymerase chain reaction (PCR). Three of them were considered immunocompromised hosts given the fact that two of these patients were taking immunosuppressive drugs for rheumatoid arthritis, and one patient had a history of sigmoid colon cancer (four months after resection)...
February 2024: Curēus
https://read.qxmd.com/read/38524003/an-unusual-and-protracted-course-of-a-haggitt-3-malignant-polyp-recurrence
#40
Pratik Raichurkar, Tae Jun Kim, Christopher Byrne
Timely detection of colorectal cancer recurrence is paramount, as treatment of early-stage recurrence greatly improves survival and outcomes. Current guidelines outline post-resection surveillance through endoscopy, CT imaging, and tumor markers for five years; however, there is minimal data to guide follow-up beyond this. We present the case of a 60-year-old female with locoregional recurrence 15 years after endoscopic mucosal resection of a low-grade Haggit level 3 sigmoid colon polyp. Unusually the recurrence was noted as an incidental finding following investigation of an elevated alpha-fetoprotein level post liver transplant, and a retrospective review of imaging revealed a calcified sigmoid mesentery mass...
February 2024: Curēus
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