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Post-intensive care syndrome

Joanne McPeake, Mark E Mikkelsen
No abstract text is available yet for this article.
September 2018: Critical Care Medicine
Adel Elkbuli, Brandon Diaz, John D Ehrhardt, Shaikh Hai, Sean Kaufman, Mark McKenney, Dessy Boneva
INTRODUCTION: Clostridial toxic shock is a rare syndrome traditionally described in case studies and reviews as a uniformly fatal condition associated with post-partum and post-abortion. Clostridium sordellii was first mentioned in scientific literature as a human pathogen in 1922 when Argentinian microbiologist Alfredo Sordellii identified the organism in gangrenous wounds. Over the past century, there has been infrequent discussion and little awareness surrounding this serious condition...
July 29, 2018: International Journal of Surgery Case Reports
John A Ligon, Janna M Journeycake, Shellie C Josephs, Naureen G Tareen, Eduardo A Lindsay, Lawson A B Copley
BACKGROUND: Children with osteomyelitis are at risk for deep venous thrombosis (DVT). This study evaluates the characteristics of DVT among children to differentiate between those with and without osteomyelitis. METHODS: Children with DVT of any cause were studied between 2008 and 2016. Children with DVT and osteomyelitis were compared with those with DVT without osteomyelitis. Another comparison cohort included children with osteomyelitis but without DVT. Comorbidities, severity of illness (SOI), and clinical course were compared between cohorts...
August 4, 2018: Journal of Pediatric Orthopedics
Wei Gao, Na Li, Xiao-Guang Cui
OBJECTIVE: To evaluate the efficacy of Xuebijing Injection (, XBJ) on the lung injury induced by cardiopulmonary bypass (CPB). METHODS: Fifty patients undergoing CPB were randomized to either the saline group or XBJ group according to a random number table (25 cases in each group). The patients in the saline group received saline and patients in XBJ group received XBJ at 12 h prior to the operation, at the beginning of the operation, and at 12 h after the second injection...
July 31, 2018: Chinese Journal of Integrative Medicine
Rania Bouneb, Manel Mellouli, Houda Bensoltane, Jamila Baroudi, Imed Chouchene, Mohamed Boussarsar
Introduction: To describe all patients admitted to Tunisian intensive care unit with a diagnosis of influenza A/H1N1 virus infection after the 2009 influenza pandemic and to analyse their characteristics, predictors of complications and outcome. Methods: All patients with influenza > 18-years-old hospitalized to the ICU department of Tunisian University hospital of Sousse, between December 1, 2009 and March 31, 2016, with a positive influenza A/H1N1/09 reverse transcriptase polymerase chain reaction (RT-PCR) from a nasopharyngeal specimen were included, were included...
2018: Pan African Medical Journal
Ann Louise Bødker Hanifa, Anne Okkels Glæemose, Birgitte Schantz Laursen
OBJECTIVES: On an intensive care unit at a university hospital in Denmark patients are offered a nurse-led consultation three months post intensive care unit admission, to help them cope with Post Intensive Care Syndrome and identify opportunities for further intervention. The aim of the study was: 1) To describe former intensive care patients' experiences of the consultation, specifically regarding content and setting. 2) To explore the benefits of the consultation in regard to the individual patients' symptoms of Post Intensive Care Syndrome...
July 19, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
Hsin-Ju Tang, Hsin-Yi Jean Tang, Chia-Ming Chang, Pei-Fang Su, Ching-Huey Chen
Older ICU survivors are often challenged with clusters of geriatric syndromes and functional decline. The purpose of this study was (a) to assess patterns of geriatric syndromes and functional status from admission to 6 months post discharge and (b) to examine the predictors of longitudinal functional status. This is a prospective cohort study. Demographic information, clinical variables, geriatric syndromes, and functional status were collected longitudinally. A total of 192 medical ICU older adult survivors were included in the analysis...
July 1, 2018: Clinical Nursing Research
Patricia J Ohtake, Alan C Lee, Jacqueline Coffey Scott, Rana S Hinman, Naeem A Ali, Carl R Hinkson, Dale M Needham, Lori Shutter, Helene Smith-Gabai, Mary C Spires, Alecia Thiele, Clareen Wiencek, James M Smith
Background: Post-intensive care syndrome (PICS) is a constellation of new or worsening impairments in physical, mental, or cognitive abilities or a combination of these in individuals who have survived critical illness requiring intensive care. Purpose: The 2 purposes of this systematic review were to identify the scope and magnitude of physical problems associated with PICS during the first year after critical illness and to use the World Health Organization's International Classification of Functioning, Disability and Health (ICF) framework to elucidate impairments of body functions and structures, activity limitations, and participation restrictions associated with PICS...
August 1, 2018: Physical Therapy
M Raurell-Torredà, S Arias-Rivera, J D Martí, M J Frade-Mera, I Zaragoza-García, E Gallart, T R Velasco-Sanz, A San José-Arribas, E Blázquez-Martínez
AIM: To evaluate the degree of implementation of protocols associated with the prevention of intensive-care-unit (ICU) acquired muscle weakness, and the presence of the physiotherapist in various ICU in Spain. METHOD: A descriptive, cross-sectional study performed in 86 adult ICU in Spain between March and June 2017. Neurosurgical and major burns ICU were excluded. A multiple-choice survey was used that included questions on protocols for glycaemia control, sedation, pain assessment, delirium prevention, delirium management and early mobilisation...
June 28, 2018: Enfermería Intensiva
Carla M Sevin, Sarah L Bloom, James C Jackson, Li Wang, E Wesley Ely, Joanna L Stollings
PURPOSE: To describe the design and initial implementation of an Intensive Care Unit Recovery Center (ICU-RC) in the United States. MATERIALS AND METHODS: A prospective, observational feasibility study was undertaken at an academic hospital between July 2012 and December 2015. Clinical criteria were used to develop the ICU-RC, identify patients at high risk for post intensive care syndrome (PICS), and offer them post-ICU care. RESULTS: 218/307 referred patients (71%) survived to hospital discharge; 62 (28% of survivors) were seen in clinic...
August 2018: Journal of Critical Care
Jaya Chandrasekhar, Amrita Gill, Roxana Mehran
Acute myocardial infarction (AMI) is the leading cause of death in women worldwide. Every year, in the USA alone, more than 30,000 young women <55 years of age are hospitalized with AMI. In recent decades, the incidence of AMI is increasing in younger women in the context of increasing metabolic syndrome, diabetes mellitus, and non-traditional risk factors such as stress, anxiety, and depression. Although women are classically considered to present with atypical chest pain, several observational data confirm that men and women experience similar rates of chest pain, with some differences in intensity, duration, radiation, and the choice of descriptors...
2018: International Journal of Women's Health
J L Pérez-Navero, C Merino-Cejas, I Ibarra de la Rosa, S Jaraba-Caballero, M Frias-Perez, E Gómez-Guzmán, M Gil-Campos, M J de la Torre-Aguilar
OBJECTIVE: To determine the predictive value of the inotropic score (IS) and vasoactive-inotropic score (VIS) in low cardiac output syndrome (LCOS) in children after congenital heart disease surgery involving cardiopulmonary bypass (CPB), and to establish whether mid-regional pro-adrenomedullin (MR-proADM) and cardiac troponin I (cTn-I), associated to the IS and VIS scores, increases the predictive capacity in LCOS. DESIGN: A prospective observational study was carried out...
June 14, 2018: Medicina Intensiva
Michelle Ma, Katie Falloon, Po-Hung Chen, Behnam Saberi, Aliaksei Pustavoitau, Elif Ozdogan, Zhiping Li, Benjamin Philosophe, Andrew M Cameron, Ahmet Gurakar
Acute alcoholic hepatitis is a syndrome of jaundice and hepatic decompensation that occurs with excessive alcohol consumption. The diagnosis can be made with a combination of clinical characteristics and laboratory studies, though biopsy may be required in unclear cases. Acute alcoholic hepatitis can range from mild to severe disease, as determined by a Maddrey discriminant function ≥32. Mild forms can be managed with supportive care and abstinence from alcohol. While mild form has an overall good prognosis, severe alcoholic hepatitis is associated with an extremely high short-term mortality of up to 50%...
January 1, 2018: Journal of Intensive Care Medicine
Zachary D Threlkeld, Yelena G Bodien, Eric S Rosenthal, Joseph T Giacino, Alfonso Nieto-Castanon, Ona Wu, Susan Whitfield-Gabrieli, Brian L Edlow
Integrity of the default mode network (DMN) is believed to be essential for human consciousness. However, the effects of acute severe traumatic brain injury (TBI) on DMN functional connectivity are poorly understood. Furthermore, the temporal dynamics of DMN reemergence during recovery of consciousness have not been studied longitudinally in patients with acute severe TBI. We performed resting-state functional magnetic resonance imaging (rs-fMRI) to measure DMN connectivity in 17 patients admitted to the intensive care unit (ICU) with acute severe TBI and in 16 healthy control subjects...
May 12, 2018: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Nicolas Mongardon, Guillaume Savary, Guillaume Geri, Marie-Rose El Bejjani, Stéphane Silvera, Florence Dumas, Julien Charpentier, Frédéric Pène, Jean-Paul Mira, Alain Cariou
BACKGROUND: Adrenal gland volume is associated with survival in septic shock. As sepsis and post-cardiac arrest syndrome share many pathophysiological features, we assessed the association between adrenal gland volume measured by computerized tomography (CT)-scan and post-cardiac arrest shock and intensive care unit (ICU) mortality, in a large cohort of out-of-hospital cardiac arrest (OHCA) patients. We also investigated the association between adrenal hormonal function and both adrenal gland volume and outcomes...
August 2018: Resuscitation
Philip A Efron, Alicia M Mohr, Azra Bihorac, Hiroyuki Horiguchi, McKenzie K Hollen, Mark S Segal, Henry V Baker, Christiaan Leeuwenburgh, Lyle L Moldawer, Frederick A Moore, Scott C Brakenridge
As early as the 1990s, chronic critical illness, a distinct syndrome of persistent high-acuity illness requiring management in the ICU, was reported under a variety of descriptive terms including the "neuropathy of critical illness," "myopathy of critical illness," "ICU-acquired weakness," and most recently "post-intensive care unit syndrome." The widespread implementation of targeted shock resuscitation, improved organ support modalities, and evidence-based protocolized ICU care has resulted in significantly decreased in-hospital mortality within surgical ICUs, specifically by reducing early multiple organ failure deaths...
August 2018: Surgery
S Zullino, T Simoncini
SSRIs are the first choice for the treatment of mood disorders during pregnancy and lactation. Despite the known side effects, the benefits/risks balance suggests their use. Hypertensive disorders of pregnancy (HDP) and Intrauterine growth restriction (IUGR) are the main vascular effects of these drugs, with mechanisms that involves endothelial dysfunction in feto-placental system. These data are supported by animal models, even if preliminary findings are not yet adequately supported by molecular and clinical data...
September 2018: Vascular Pharmacology
Jason J Heavner, Kathleen M Akgün, Mojdeh S Heavner, Claire C Eng, Matthew Drew, Peter Jackson, David Pritchard, Shyoko Honiden
STUDY OBJECTIVE: Alcohol use disorders are prevalent and put patients at risk for developing alcohol withdrawal syndrome (AWS). Treatment of AWS with a symptom-triggered protocol standardizes management and may avoid AWS-related complications. The objective of this study was to evaluate whether implementation of a specific intensive care unit (ICU) symptom-triggered protocol for the management of AWS was associated with improved clinical outcomes and, in particular, would reduce the risk of patients with AWS requiring mechanical ventilation...
May 25, 2018: Pharmacotherapy
S S Mørch, S Tantholdt-Hansen, N E Pedersen, C L Duus, J A Petersen, C Ø Andersen, J O Jarløv, C S Meyhoff
BACKGROUND: Post-operative sepsis considerably increases mortality, but the extent of pre-operative sepsis in hip fracture patients and its consequences are sparsely elucidated. The aim of this study was to assess the association between pre-operative sepsis and 30-day mortality after hip fracture surgery. METHODS: We conducted a retrospective analysis of data collected among 1894 patients who underwent hip fracture surgery in the Capital Region of Denmark in 2014 (NCT03201679)...
May 24, 2018: Acta Anaesthesiologica Scandinavica
Annachiara Marra, Pratik P Pandharipande, Timothy D Girard, Mayur B Patel, Christopher G Hughes, James C Jackson, Jennifer L Thompson, Rameela Chandrasekhar, Eugene Wesley Ely, Nathan E Brummel
OBJECTIVES: To describe the frequency of cooccurring newly acquired cognitive impairment, disability in activities of daily livings, and depression among survivors of a critical illness and to evaluate predictors of being free of post-intensive care syndrome problems. DESIGN: Prospective cohort study. SETTING: Medical and surgical ICUs from five U.S. centers. PATIENTS: Patients with respiratory failure or shock, excluding those with preexisting cognitive impairment or disability in activities of daily livings...
May 21, 2018: Critical Care Medicine
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