Wenfeng Zhu, Weilong Wang, Wenjie Zheng, Xiaolong Chen, Xiaowen Wang, Juping Xie, Shijie Jiang, Haoqi Chen, Shuguang Zhu, Ping Xue, Xiaofeng Jiang, Hua Li, Genshu Wang
Protein induced by vitamin K absence or antagonist II (PIVKA-II) plays a critical role in the diagnosis of hepatocellular carcinoma (HCC), however, studies on its efficacy in diagnosing recurrent HCC were rarely found. A multicenter, retrospective, and observational study was conducted. During the overall follow-up of 5 years, HCC patients who had curative resection were monitored every 3 months in the first year post-surgery and every 6 months thereafter if no recurrence occurred. Tumor markers were collected at the diagnosis of recurrence for those with recurrence and at the last follow-up for those without recurrence...
April 10, 2024: Scientific Reports