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Vitamin surgery

Mahdieh Abbasalizad Farhangi, Mahdi Najafi
AIMS: Recently, the clinical importance of total antioxidant capacity (TAC) and its protective role against several chronic diseases like cardiovascular disease, osteoporosis and several types of cancers has been reported. However, its association with cardio-metabolic risk factors among patients candidate for coronary artery bypass graft surgery (CABG) has not been evaluated yet. CABG is associated with increased oxidative stress and free radicals; so, the current study was aimed to evaluate the potential association of TAC with cardiovascular risk factors among patients candidate for CABG...
2018: PloS One
Tomas K Kuprys, Leah M Steinmetz, Charla R Fischer, Themistocles S Protopsaltis, Peter G Passias, Jeffrey A Goldstein, John A Bendo, Thomas J Errico, Aaron J Buckland
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: The goals of this study were to (1) evaluate pre-operative bone quality assessment and intervention practice over time and (2) review the current evidence for bone evaluation in spine fusion surgery. SUMMARY OF BACKGROUND DATA: Deformity spine surgery has demonstrated improved quality of life in patients however its cost has made it controversial. If pre-operative bone quality can be optimized then potentially these treatments could be more durable however, at present, no clinical practice guidelines have been published by professional spine surgical organizations...
December 11, 2018: Spine
Álvaro Antonio Bandeira Ferraz, Márcio R C Carvalho, Luciana T Siqueira, Fernando Santa-Cruz, Josemberg Marins Campos
OBJECTIVE: to compare the prevalence of micronutrient deficiencies in patients submitted to sleeve gastrectomy (SG) and Roux- en-Y gastric bypass (RYGB). METHODS: this is a comparative study of 576 patients submitted to bariatric surgery, 338 to SG and 238 to RYGB, and evaluated for hemoglobin, iron, ferritin, zinc and vitamin B12 serum levels. We performed these dosages in the preoperative period and at three, six, 12 and 24 months after surgery, for analysis and comparison of micronutrient deficiencies among the techniques...
December 10, 2018: Revista do Colégio Brasileiro de Cirurgiões
Nathalia Ramori Farinha Wagner, Marilia Rizzon Zaparolli, Magda Rosa Ramos Cruz, Maria Eliana Madalozzo Schieferdecker, Antônio Carlos Ligocki Campos
INTRODUCTION: Studies suggest that weight loss induced by bariatric surgery and the remission of some comorbidities may be related to changes in the microbiota profile of individuals undergoing this procedure. In addition, there is evidence that manipulation of the intestinal microbiota may prove to be a therapeutic approach against obesity and metabolic diseases. OBJECTIVE: To verify the changes that occur in the intestinal microbiota of patients undergoing bariatric surgery, and the impact of the usage of probiotics in this population...
December 6, 2018: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
Sejin Ha, Sujin Park, Hyunji Kim, Heounjeong Go, Seung Hun Lee, Ji Yoon Choi, Jung Yong Hong, Jin-Sook Ryu
Diagnosing tumor-induced osteomalacia is often challenging because conventional imaging modalities may fail to locate the responsible tumor. This report describes the ability of 68 Ga-DOTATOC PET/CT to successfully distinguish between the responsible phosphaturic mesenchymal tumor and concurrent lymphoma lesions. A 52-year-old man with bone pain for several years was diagnosed with a vitamin D-resistant hypophosphatemic osteomalacia. Whole body 18 F-FDG PET/CT revealed multiple enlarged hypermetabolic lymph nodes in his bilateral cervical, axillary, mediastinal, abdominal, pelvic, and inguinal regions...
December 2018: Nuclear Medicine and Molecular Imaging
Cheng-Chia Lee, Ya-Ju Hsieh, Shao-Wei Chen, Shu-Hsuan Fu, Chia-Wei Hsu, Chih-Ching Wu, Wei Han, Yunong Li, Tao Huan, Yu-Sun Chang, Jau-Song Yu, Liang Li, Chih-Hsiang Chang, Yi-Ting Chen
The development of Bretschneider's histidine-tryptophan-ketoglutarate (HTK) cardioplegia solution represented a major advancement in cardiac surgery, offering significant myocardial protection. However, metabolic changes induced by this additive in the whole body have not been systematically investigated. Using an untargeted mass spectrometry-based method to deeply explore the urine metabolome, we sought to provide a holistic and systematic view of metabolic perturbations occurred in patients receiving HTK...
December 11, 2018: Scientific Reports
Lisiane Stefani Dias, Otto Henrique Nienov, Fernanda Dapper Machado, Camila Perlin Ramos, Daiane Rodrigues, Rodrigo Koprovsky Menguer, Helena Schmid
BACKGROUND: Obesity and its complications are prevalent in women and increase with age. Polyneuropathy (PNP) is a complication of obesity and bariatric surgery (BS). In subjects with severe (grades II and III) obesity and without DM who are candidates for BS, the prevalence of PNP and associated conditions are not well characterized. The aim of this study was to evaluate the prevalence of PNP in severely obese (SO) women without DM or common nutritional deficiencies in order to determine factors associated with the presence of PNP...
December 7, 2018: Obesity Surgery
Mirian Alejo Ramos, Isidoro M Cano Rodríguez, Ana M Urioste Fondo, Begoña Pintor de la Maza, David E Barajas Galindo, Paula Fernández Martínez, Luis González Herráez, Tomás González de Francisco, María D Ballesteros Pomar
BACKGROUND: Secondary hyperparathyroidism (SHPT) is a matter of concern after biliopancreatic diversion (BPD). The aim of this study was to investigate the relationship between SHPT, 25(OH)D, and calcium after BPD. DESIGN: A retrospective analysis in obese patients after BPD performed between 1998 and 2016. METHODS: Patients with at least 1 year of follow-up were included. SHPT was considered when PTH > 65 pg/mL in the absence of an elevated corrected calcium...
December 6, 2018: Obesity Surgery
Gwang-Ho Choi, L Susan Wieland, Hyangsook Lee, Hoseob Sim, Myeong Soo Lee, Byung-Cheul Shin
BACKGROUND: Carpal tunnel syndrome (CTS) is a compressive neuropathic disorder at the level of the wrist. Acupuncture and other methods that stimulate acupuncture points, such as electroacupuncture, auricular acupuncture, laser acupuncture, moxibustion, and acupressure, are used in treating CTS. Acupuncture has been recommended as a potentially useful treatment for CTS, but its effectiveness remains uncertain. We used Cochrane methodology to assess the evidence from randomised and quasi-randomised trials of acupuncture for symptoms in people with CTS...
December 2, 2018: Cochrane Database of Systematic Reviews
Benedikt Becker, Christopher Netsch, Jens Hansen, Axel Böhme, Andreas J Gross, Mario Zaccharias, Karin Lehrich
Introduction & Objectives To evaluate the safety of holmium laser enucleation of the prostate (HoLEP) in patients on oral anticoagulation (OA) with respect to intra- and postoperative bleeding complications. Methods Between 01/2013 and 10/2016, 2178 patients were included in this study, of whom 94 received direct oral anticoagulants (DOACs) and 151 received Vitamin K antagonists (VKAs) before HoLEP. All patients either ceased OA (DOACs) or were bridged subtherapeutically (VKAs, INR<2) during surgery...
December 5, 2018: Journal of Endourology
Daniel J Morgan, Sanket S Dhruva, Eric R Coon, Scott M Wright, Deborah Korenstein
Importance: Overuse of medical care is a well-recognized problem in health care, associated with patient harm and costs. We sought to identify and highlight original research articles published in 2017 that are most relevant to understanding medical overuse. Observations: A structured review of English-language articles published in 2017 was performed, coupled with examination of tables of contents of high-impact journals to identify articles related to medical overuse in adult care...
December 3, 2018: JAMA Internal Medicine
Iqbal Sayeed, Nefize Turan, Donald G Stein, Bushra Wali
Because vitamin D hormone deficiency (VDHdef ) can worsen severity and outcome for ischemic stroke, we examined the role of VDH in maintaining blood-brain-barrier (BBB integrity) in a rat model of stroke. In most types of stroke, the BBB is markedly compromised, potentially leading to a cascade of injury processes and functional deficits, so we examined a number of biomarkers associated with BBB disruption to determine whether VDH deficiency would further compromise the BBB following a stroke. Male Wistar rats were randomly assigned to one of two diet cohorts, VDH-sufficient (VDHsuf ) and VDHdef ...
November 28, 2018: Experimental Neurology
V P Galea, J W Connelly, B Shareghi, J Kärrholm, O Sköldenberg, M Salemyr, M B Laursen, O Muratoglu, C Bragdon, H Malchau
AIMS: The primary aim of this study was to compare the wear properties of vitamin E-diffused, highly crosslinked polyethylene (VEPE) and one formulation of moderately crosslinked and mechanically annealed ultra-high molecular weight polyethylene (ModXLPE) in patients five years after primary total hip arthroplasty (THA). The secondary aim was to assess the clinical results of patients treated with VEPE by evaluating patient-reported outcome measures (PROMs), radiological evidence of fixation, and the incidence of mechanical failure...
December 2018: Bone & Joint Journal
C Daugaard, A B Pedersen, N R Kristensen, S P Johnsen
Hip fracture surgery is associated with high risk of bleeding and mortality. The patients often have cardiovascular comorbidity, which requires antithrombotic treatment. This study found that preoperative use of oral anticoagulants was not associated with transfusion or mortality following hip fracture surgery, whereas increased risk may exist for antiplatelet drugs. INTRODUCTION: Hip fracture surgery is associated with high bleeding risk and mortality; however, data on operative outcomes of hip fracture patients admitted while on antithrombotic therapy is sparse...
November 29, 2018: Osteoporosis International
Seyhan Dikci, Emrah Öztürk, Penpe Gül Fırat, Turgut Yılmaz, Mehmet Çağatay Taşkapan, Saim Yoloğlu
OBJECTIVE: To investigate whether serum vitamin D levels have an effect on pseudoexfolation (PEX) glaucoma/syndrome development and on the control of glaucoma in these cases. METHOD: A total of 31 cases with PEX glaucoma, 34 cases with the PEX syndrome and 43 control subjects of similar age and sex were included in the study. Vitamin D levels were compared between the groups and also between the cases where glaucoma surgery was performed or not. RESULTS: PEX glaucoma group consisted of 17 males and 14 females, PEX syndrome group of 27 males and 7 females, and the control group of 27 males and 16 females...
November 27, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
Fernando Mendoza-Moreno, Manuel Díez-Alonso, Enrique Ovejero-Merino, Ana Sánchez-Gollarte, Ricardo Alvarado-Hurtado, Belén Matías-García, Ángel Rodríguez-Pascual, Carlos Medina-Reinoso, Tomás Ratia-Jiménez, Francisco Hernández-Merlo, Javier Granell-Vicent
AIM: To analyze the effect of the surgery in bone mineral density (BMD) and to study the value of preoperative clinical and analytical factors as predictors of bone increase. MATERIAL AND METHODS: Prospective observational study. Postmenopausal women who were operated for primary hyperparathyroidism were included. A bone densitometry of the lumbar spine and femoral neck and analytical determinations (parathyroid hormone [PTH], alkaline phosphatase, albumin, phosphate, creatinine, 25-hydroxy-vitamin D3, creatinine clearance, and calciuria) were performed previous to the intervention and after 12 months from surgery...
November 9, 2018: Journal of Clinical Densitometry
Barbara C Silva, Natalie E Cusano, John P Bilezikian
Primary hyperparathyroidism (PHPT), the most common cause of hypercalcemia, is most often identified in postmenopausal women with hypercalcemia and parathyroid hormone (PTH) levels that are either frankly elevated or inappropriately normal. The clinical presentation of PHPT includes three phenotypes: target organ involvement of the renal and skeletal systems; mild asymptomatic hypercalcemia; and more recently, high PTH levels in the context of persistently normal albumin-corrected and ionized serum calcium values...
September 28, 2018: Best Practice & Research. Clinical Endocrinology & Metabolism
Svea-Vivica Mathieu, Karina Fischer, Bess Dawson-Hughes, Gregor Freystaetter, Felix Beuschlein, Simeon Schietzel, Andreas Egli, Heike A Bischoff-Ferrari
Obesity and sarcopenia are major causes of morbidity and mortality among seniors. Vitamin D deficiency is very common especially among seniors and has been associated with both muscle health and obesity. This study investigated if 25-hydroxyvitamin D (25(OH)D) status is associated with body composition and insulin resistance using baseline data of a completed RCT among relatively healthy community-dwelling seniors (271 seniors age 60+ years undergoing elective surgery for unilateral total knee replacement due to osteoarthritis)...
November 25, 2018: Nutrients
William Sellers, Charles Bendas, Frederick Toy, Brian Klock, Jamie Kerestes, Amanda Young, Clint Badger, Jason Jensen, Natasha Becker
Context: Since 2013, prothrombin complex concentrate (PCCs) have been approved in the United States for the reversal of anticoagulation induced by vitamin K antagonists. However, there has been limited investigation into their use in trauma and acute-care surgery (ACS). Objective: To investigate the role that 4-factor PCC may have in reversing anticoagulation in the setting of trauma and ACS. Methods: All trauma and ACS patients who presented between March 14, 2014, and August 1, 2015, were included in this retrospective descriptive analysis...
December 1, 2018: Journal of the American Osteopathic Association
K H Chan, E A Moser, B M Whittam, R Misseri, M P Cain, A Krambeck, A Schwaderer
INTRODUCTION: Approximately half of adult stone formers submit specimens that are either under or over collections as determined by 24-h creatinine/kg. Previously identified predictors of inadequate collection in adults include female sex, older age, higher body mass index (BMI), vitamin D supplementation, and weekday collection. OBJECTIVE: The objective of this study is to determine risk factors for inadequate 24-h urinary specimen collection in the pediatric population...
October 28, 2018: Journal of Pediatric Urology
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