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https://www.readbyqxmd.com/read/30500963/placenta-accreta-a-spectrum-of-predictable-risk-diagnosis-and-morbidity
#1
Christina M Duzyj, Anne Cooper, Mohak Mhatre, Christina S Han, Michael J Paidas, Jessica L Illuzzi, Anna K Sfakianaki
OBJECTIVE:  Placenta accreta is a feared pathology, in part, because prenatal diagnosis is imperfect. It is not known whether clinical risk factors or sonographic features equally predict the entire graded pathological spectrum of placental overinvasion disease nor whether clinical outcomes differ along the spectrum. STUDY DESIGN:  We conducted a mixed methods retrospective study of a cohort of women screened sonographically for placenta accreta, cross-referenced against cases identified by pathological diagnosis ( N  = 416)...
November 30, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/30496259/ovarian-reserve-after-uterine-artery-embolization-in-women-with-morbidly-adherent-placenta-a-cohort-study
#2
Aya Mohr-Sasson, Maya Spira, Rony Rahav, Dafna Manela, Eyal Schiff, Shali Mazaki-Tovi, Raoul Orvieto, Eyal Sivan
OBJECTIVE: To evaluate ovarian reserve in women after preservative cesarean delivery using uterine artery embolization due to morbidly adherent placenta. STUDY DESIGN: A historical cohort study including all women admitted to a single tertiary care center, with morbidly adherent placenta that had preservative cesarean delivery with bilateral uterine artery embolization. Inclusion criteria included gestational age >24 weeks, singleton pregnancy and placenta increta / percreta...
2018: PloS One
https://www.readbyqxmd.com/read/30471891/placenta-accreta-spectrum
#3
Alison G Cahill, Richard Beigi, R Phillips Heine, Robert M Silver, Joseph R Wax
Placenta accreta spectrum, formerly known as morbidly adherent placenta, refers to the range of pathologic adherence of the placenta, including placenta increta, placenta percreta, and placenta accreta. The most favored hypothesis regarding the etiology of placenta accreta spectrum is that a defect of the endometrial-myometrial interface leads to a failure of normal decidualization in the area of a uterine scar, which allows abnormally deep placental anchoring villi and trophoblast infiltration. Maternal morbidity and mortality can occur because of severe and sometimes life-threatening hemorrhage, which often requires blood transfusion...
December 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30462321/hezeb2-a-master-regulator-of-the-epithelial-mesenchymal-transition-mediates-trophoblast-differentiation
#4
Sonia DaSilva-Arnold, Che-Ying Kuo, Viralkumar Davra, Yvonne Remache, Peter C W Kim, John P Fisher, Stacy Zamudio, Abdulla Al-Khan, Raymond B Birge, Nicholas P Illsley
STUDY QUESTION: Does the upregulation of the zinc finger E-box binding homeobox 2 (ZEB2) transcription factor in human trophoblast cells lead to alterations in gene expression consistent with an epithelial-mesenchymal transition (EMT) and a consequent increase in invasiveness? SUMMARY ANSWER: Overexpression of ZEB2 results in an epithelial-mesenchymal shift in gene expression accompanied by a substantial increase in invasive capacity of human trophoblast cells. WHAT IS KNOWN ALREADY: In-vivo results have shown that cytotrophoblast differentiation into extravillous trophoblast involves an epithelial-mesenchymal transition...
November 21, 2018: Molecular Human Reproduction
https://www.readbyqxmd.com/read/30461695/obstetric-care-consensus-no-7-placenta-accreta-spectrum
#5
(no author information available yet)
Placenta accreta spectrum, formerly known as morbidly adherent placenta, refers to the range of pathologic adherence of the placenta, including placenta increta, placenta percreta, and placenta accreta. The most favored hypothesis regarding the etiology of placenta accreta spectrum is that a defect of the endometrial-myometrial interface leads to a failure of normal decidualization in the area of a uterine scar, which allows abnormally deep placental anchoring villi and trophoblast infiltration. Maternal morbidity and mortality can occur because of severe and sometimes life-threatening hemorrhage, which often requires blood transfusion...
December 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30461691/obstetric-care-consensus-no-7-summary-placenta-accreta-spectrum
#6
(no author information available yet)
Placenta accreta spectrum, formerly known as morbidly adherent placenta, refers to the range of pathologic adherence of the placenta, including placenta increta, placenta percreta, and placenta accreta. The most favored hypothesis regarding the etiology of placenta accreta spectrum is that a defect of the endometrial-myometrial interface leads to a failure of normal decidualization in the area of a uterine scar, which allows abnormally deep placental anchoring villi and trophoblast infiltration. Maternal morbidity and mortality can occur because of severe and sometimes life-threatening hemorrhage, which often requires blood transfusion...
December 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30448828/clinical-and-ultrasound-predictors-of-placenta-accreta-in-pregnant-women-with-antepartum-diagnosis-of-placenta-previa-a-multicenter-study
#7
Davide De Vita, Giampiero Capobianco, Giovanni Gerosolima, Carmen Sciorio, Ermenegilda Coppola, Fabio Parazzini, Maurizio Silvestri, Anna Paola Caruso, Maddalena Morlando, Raffaele Petta, Alessandro Pascarella, Salvatore Dessole, Elsa Viora
BACKGROUND/AIMS: Abnormally invasive placenta (AIP) includes placenta accreta, increta, and percreta and represents major complications of pregnancy. This study was designed to assess the role of ultrasonography in the identification of AIP among pregnant women with antepartum diagnosis of placenta previa. METHODS: A cross-sectional study was performed between May 2015 and April 2016 in 11 centers, including 242 women with antepartum diagnosis of placenta previa...
November 16, 2018: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/30431609/a-prospective-evaluation-and-management-of-different-types-of-placenta-praevia-using-parallel-vertical-compression-suture-to-preserve-uterus
#8
COMPARATIVE STUDY
Adrian C Ratiu, Doru C Crisan
The rising tendency of cesarean sections will lead invariably to more complications such as placenta praevia. The aim of our study was to evaluate the utility of parallel vertical compression suture to preserve uterus in cases of placenta praevia, and to propose a rational approach of these problematic cases, according to their grade of myometrial invasion.We prospectively included 95 consecutive cases diagnosed with placenta praevia (group1 [Gr1]) where we used parallel compression suture and compared to retrospectively analyzed 100 consecutive cases managed without using this technique (group 2 [Gr2])...
November 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30293299/-rupture-of-uterus-and-penetrated-small-intestine-caused-by-placenta-percreta-a-case-report
#9
S Y Hou, Y H Qian, H J Jia
No abstract text is available yet for this article.
September 25, 2018: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/30258488/resuscitative-endovascular-balloon-occlusion-of-the-aorta-deployed-by-acute-care-surgeons-in-patients-with-morbidly-adherent-placenta-a-feasible-solution-for-two-lives-in-peril
#10
REVIEW
Ramiro Manzano-Nunez, Maria F Escobar-Vidarte, Claudia P Orlas, Juan P Herrera-Escobar, Samuel M Galvagno, Juan J Melendez, Natalia Padilla, Justin C McCarty, Albaro J Nieto, Carlos A Ordoñez
Morbidly adherent placenta (MAP), which includes accreta, increta, and percreta, is a condition characterized by the invasion of the uterine wall by placental tissue. The condition is associated with higher odds of massive post-partum hemorrhage. Several interventions have been developed to improve hemorrhage-related outcomes in these patients; however, there is no evidence to prefer any intervention over another. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an endovascular intervention that may be useful and effective to reduce hemorrhage and transfusions in MAP patients...
2018: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/30246313/new-three-dimensional-four-dimensional-volume-rendering-imaging-software-for-detecting-the-abnormally-invasive-placenta
#11
Rozi Aditya Aryananda, Aldika Akbar, Manggala Pasca Wardhana, Khanisyah Erza Gumilar, Budi Wicaksono, Ernawati Ernawati, Agus Sulistyono, Aditiawarman Aditiawarman, Hermanto Tri Joewono, Erry Gumilar Dachlan, Anupam Parange, Gustaaf Albert Dekker
OBJECTIVE: This study aimed to determine the role of three-dimensional (3D)/four-dimensional (4D) volume rendering ultrasound (VRU) in the diagnosis of abnormally invasive placenta (AIP). MATERIALS AND METHODS: Twelve consecutive patients strongly suspected of having AIP on the basis of conventional ultrasound (US) and clinical history performed between September 2016 and December 2016 in the main tertiary referral hospital in Surabaya, East Java were included in this prospective observational study...
September 23, 2018: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/30245897/hysterectomy-with-fetus-in-situ-for-uterine-rupture-at-21-week-gestation-due-to-a-morbidly-adherent-placenta
#12
Katerina Pizzuto, Cory Ozimok, Radenka Bozanovic, Kathleen Tafler, Sarah Scattolon, Nicholas A Leyland, Michelle Morais
Background: Uterine rupture due to a morbidly adherent placenta is a rare obstetrical cause of acute abdominal pain in the pregnant patient. We present a case to add to the small body of published literature describing this diagnosis. Case: A 32-year-old G5T2P1A1L2 with multiple prior cesarean sections presented at 21+3 weeks' gestation with abdominal pain and presyncope. Ultrasound showed a large volume of complex intraabdominal free fluid and a heterogenous placenta with irregular lacunae and increased vascularity extending to the posterior bladder wall...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30215463/the-role-of-osteopontin-in-the-pathogenesis-of-placenta-percreta
#13
Alev Özer, Aslı Yaylalı, Sezen Koçarslan
OBJECTIVE: This study aims to determine how the expression of osteopontin is altered in the placenta percreta by compar-ing osteopontin expression in normal placentas and placenta percreta tissues. MATERIAL AND METHODS: Placental tissues from hysterectomy materials which were histopathologically diagnosed with placenta percreta (study group, n = 20) and placental tissues obtained from normal term pregnancies (control group, n = 20) were immunohistochemically stained with osteopontin antibody...
2018: Ginekologia Polska
https://www.readbyqxmd.com/read/30211800/use-of-postpartum-magnetic-resonance-imaging-for-diagnosis-and-classification-of-retained-placenta-tissue
#14
Shui-Hua Zhang, Jia-Yun Zhang, Jing Zhang, Wen-Li Chen, Quan Zhou
OBJECTIVE: To study the potential application of magnetic resonance imaging (MRI) for classification of retained placental tissue (RPT) in the uterus postnatally. METHODS: Twenty-two patients with clinically or pathologically proven RPT were studied. RESULTS: The thickness ratio (D1/D2) of invaded (D1) to normal (D2) myometrium could be categorized into 3 groups (>0.6, 0.1-0.6, and <0.1) correlating with the 3 types of RPT: accreta vera (RPA), increta (RPI), and percreta (RPP) (r = -0...
September 10, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/30210239/placenta-percreta-complicated-by-uterine-rupture-and-thrombotic-microangiopathy
#15
Dalia Laužikienė, Saulius Vosylius, Ieva Šiaudinytė, Emilis Laužikas, Diana Ramašauskaitė, Daiva Bartkevičienė
Background: Uterine rupture at the site of a previous caesarean scar with abnormal placental penetration through the uterus wall with bladder invasion is a rare and serious pregnancy complication. Our aim was to report a case of uterine rupture with placenta percreta complicated by thrombotic microangiopathy. Materials and methods: We did a literature review and analysed medical documentation retrospectively. Results: A patient was admitted with complaints of lower abdominal pain at 21 weeks of gestation...
2018: Acta Medica Lituanica
https://www.readbyqxmd.com/read/30186710/early-accreta-and-uterine-rupture-in-the-second-trimester
#16
Joshua A Ronen, Krystal Castaneda, Sara Y Sadre
The differential diagnosis of third trimester bleeding can range from placenta abruptia to placenta previa to uterine rupture and the placenta accreta spectrum (PAS). However, patients with risk factors such as multiple cesarean sections (c-sections), advanced maternal age (AMA), grand multiparity, and single-layer uterine closure are at greater risk of developing these complications earlier than we would traditionally expect. This case recounts a 38-year-old gravida 6 preterm 3 term 1 abortus 1 live 4 (G6P3114) at 23 weeks and five days gestational age (GA) with a past medical history of preterm pregnancy, pre-eclampsia, chronic abruptia, three previous c-sections, and low-lying placenta who presented to the emergency department (ED) with vaginal bleeding...
July 1, 2018: Curēus
https://www.readbyqxmd.com/read/30136333/preoperative-cystoscopy-could-determine-the-severity-of-placenta-accreta-spectrum-disorders-an-observational-study
#17
Abdulla Al-Khan, George Guirguis, Stacy Zamudio, Manuel Alvarez, Kristina Martimucci, Davlyn Luke, Jesus Alvarez-Perez
AIM: In the surgical treatment of placenta accreta spectrum disorders, cystoscopy for prophylactic stent placement is performed to protect the ureters from potential injury. Despite its frequent use, the use of cystoscopy in assessing the severity of these disorders has not been explored. Our objective was to find out if the abnormal findings documented during cystoscopy are associated with disease severity. METHODS: In this retrospective, observational cohort study (n = 56), the bladder wall was evaluated at the time of ureteral stent placement via cystoscopy in prenatally diagnosed placenta accreta spectrum cases...
August 23, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/30078255/-application-of-cervical-lifting-suture-in-hemostasis-of-placenta-previa-with-increta-and-percreta
#18
Y S Chen, Y Y Zhao, Y Zhang, Y Wang, Y W Zhong, A Q Zhang
Objective: To evaluate the effect of cervical lifting suture in treatment of placenta previa with increta and percreta. Methods: From January 2016 to June 2017, 65 cases (0.78%, 65/8 322) were diagnosed placenta previa with increta and percreta by prenatal ultrasonic score system and confirmed by intraoperative findings in the department of obstetrics and gynecology of Peking University Third Hospital. Totally 62 cases (0.75%, 62/8 322) were included, because 3 cases underwent hysterectomy with placenta in situ...
July 25, 2018: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/30057649/placenta-accreta-spectrum-a-review-of-pathology-molecular-biology-and-biomarkers
#19
REVIEW
Helena C Bartels, James D Postle, Paul Downey, Donal J Brennan
Background . Placenta accreta spectrum (PAS) is a condition of abnormal placental invasion encompassing placenta accreta, increta, and percreta and is a major cause of severe maternal morbidity and mortality. The diagnosis of a PAS is made on the basis of histopathologic examination and characterised by an absence of decidua and chorionic villi are seen to directly adjacent to myometrial fibres. The underlying molecular biology of PAS is a complex process that requires further research; for ease, we have divided these processes into angiogenesis, proliferation, and inflammation/invasion...
2018: Disease Markers
https://www.readbyqxmd.com/read/30057428/-filling-the-bladder-at-cesarean-hysterectomy-for-placenta-percreta
#20
Shigeki Matsubara
No abstract text is available yet for this article.
July 2018: Geburtshilfe und Frauenheilkunde
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