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Ileana Hancu, Alexandre Boutet, Eric Fiveland, Manish Ranjan, Julia Prusik, Marisa Dimarzio, Tanweer Rashid, Jeffrey Ashe, David Xu, Suneil K Kalia, Mojgan Hodaie, Alfonso Fasano, Walter Kucharczyk, Julie Pilitsis, Andres Lozano, Radhika Madhavan
BACKGROUND: The majority of Parkinson's disease patients with deep brain stimulation (DBS) use a monopolar configuration, which presents challenges for EEG and MRI studies. The literature reports algorithms to convert monopolar to bipolar settings. PURPOSE/HYPOTHESIS: To assess brain responses of Parkinson's disease patients implanted with DBS during fMRI studies using their clinical and presumed equivalent settings using a published conversion recipe. STUDY TYPE: Prospective...
December 15, 2018: Journal of Magnetic Resonance Imaging: JMRI
Paola Clauser, Thomas H Helbich, Panagiotis Kapetas, Katja Pinker, Maria Bernathova, Ramona Woitek, Andreas Kaneider, Pascal A T Baltzer
BACKGROUND: Contrast-enhanced magnetic resonance imaging (CE-MRI) of the breast is highly sensitive for breast cancer detection. Multichannel coils and 3T scanners can increase signal, spatial, and temporal resolution. In addition, the T1 -reduction effect of a gadolinium-based contrast agent (GBCA) is higher at 3T. Thus, it might be possible to reduce the dose of GBCA at 3T without losing diagnostic information. PURPOSE: To compare a three-quarter (0.075 mmol/kg) dose of the high-relaxivity GBCA gadobenate dimeglumine, with a 1...
December 15, 2018: Journal of Magnetic Resonance Imaging: JMRI
Elise Kvalsund Bårdsgjerde, Marit Kvangarsnes, Bodil Landstad, Magne Nylenna, Torstein Hole
AIM: To explore how patients in areas without local percutaneous coronary intervention facilities experience patient participation in different phases of the myocardial infarction pathway. BACKGROUND: Acute treatment of myocardial infarction often involves percutaneous coronary intervention. In Norway, this treatment is centralized at certain hospitals; thus, patients often require long-distance transportation and experience frequent hospital transfers. Short hospital stays, transfers between hospitals and the patient's emotional state pose challenges to promoting patient participation...
December 14, 2018: Journal of Advanced Nursing
Dimitri Martel, Benjamin Leporq, Amit Saxena, H Michael Belmont, Gabrielle Turyan, Stephen Honig, Ravinder R Regatte, Gregory Chang
BACKGROUND: Osteoporosis (OP) results in weak bone and can ultimately lead to fracture. Drugs such as glucocorticoids can also induce OP (glucocorticoid-induced osteoporosis [GIO]). Bone marrow adipose tissue composition and quantity may play a role in OP pathophysiology, but has not been thoroughly studied in GIO compared to primary OP. PURPOSE/HYPOTHESIS: Chemical shift-encoded (CSE) MRI allows detection of subregional differences in bone marrow adipose tissue composition and quantity in the proximal femur of GIO compared to OP subjects and has high agreement with the reference standard of magnetic resonance spectroscopy (MRS)...
December 12, 2018: Journal of Magnetic Resonance Imaging: JMRI
Xinran Zhong, Sepideh Shakeri, Dapeng Liu, James Sayre, Steven S Raman, Holden H Wu, Kyunghyun Sung
BACKGROUND: Variable flip angle (VFA) imaging is widely used for the estimation of T1 relaxation in the prostate, but may have limited repeatability and reproducibility due to its sensitivity to B1 + inhomogeneity. PURPOSE: To assess the repeatability and reproducibility of prostate T1 estimation with and without compensating for B1 + variation. STUDY TYPE: Prospective. POPULATION: Twenty-one volunteers were prospectively recruited and scanned twice on two 3 T MRI scanners, resulting in 84 VFA T1 exams...
December 12, 2018: Journal of Magnetic Resonance Imaging: JMRI
Aleksi Lehikoinen, Lluís Brotons, John Calladine, Tommaso Campedelli, Virginia Escandell, Jiri Flousek, Christoph Grueneberg, Fredrik Haas, Sarah Harris, Sergi Herrando, Magne Husby, Frederic Jiguet, John Atle Kålås, Åke Lindström, Romain Lorrillière, Blas Molina, Clara Pladevall, Gianpiero Calvi, Thomas Sattler, Hans Schmid, Päivi M Sirkiä, Norbert Teufelbauer, Sven Trautmann
Mountain areas often hold special species communities, and they are high on the list of conservation concern. Global warming and changes in human land use, such as grazing pressure and afforestation, have been suggested to be major threats for biodiversity in the mountain areas, affecting species abundance and causing distribution shifts towards mountaintops. Population shifts towards poles and mountaintops have been documented in several areas, indicating that climate change is one of the key drivers of species' distribution changes...
December 11, 2018: Global Change Biology
Di Xin, Magne Bisgaard, Hans-Jürgen Busse, Rikke H Olsen, Claudia Hess, Bent Aalbæk, John E Olsen, Henrik Christensen
Bacteria isolated from lesions as well as apparently normal tissues of psittacine birds have previously been reported as taxon 37 and taxon 44 of Bisgaard. 16S rRNA gene sequence comparisons revealed a distant relationship to members of Pasteurellaceae at the species, genus and family levels. The polar lipid profile consisted of the major components phosphatidylethanolamine and phosphatidylglycerol. A new family Psittacicellaceae fam. nov. is proposed with the type genus Psittacicella gen. nov. The new genus Psittacicella includes the type species Psittacicella melopsittaci sp...
December 13, 2018: International Journal of Systematic and Evolutionary Microbiology
Toril Holien, Kristine Misund, Oddrun Elise Olsen, Katarzyna Anna Baranowska, Glenn Buene, Magne Børset, Anders Waage, Anders Sundan
[This corrects the article DOI: 10.18632/oncotarget.4245.].
November 13, 2018: Oncotarget
Alice Desclaux, Magne Sandrine Malan, Marc Egrot, Francis Akindès, Khoudia Sow
INTRODUCTION: In an epidemic context, the identification of suspected cases, among alert or contact cases, leads to caring for persons for whom only a minority will be confirmed cases, with a laboratory diagnosis positive for Ebola. How are suspected cases treated that are not subsequently confirmed and how do they feel about this experience? What are the medical or social consequences? METHODS: A qualitative study was conducted in two countries with a high Ebola risk epidemic situation in 2015-2016 (Senegal, Côte d'Ivoire)...
October 22, 2018: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
Ruitian Song, Ralf B Loeffler, Joseph L Holtrop, M Beth McCarville, Jane S Hankins, Claudia M Hillenbrand
No abstract text is available yet for this article.
February 2019: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
Enedino Hernández-Torres, Vanessa Wiggermann, Lindsay Machan, A Dessa Sadovnick, David K B Li, Anthony Traboulsee, Simon Hametner, Alexander Rauscher
BACKGROUND: Magnetic resonance relaxometry studies in multiple sclerosis (MS) have suggested that iron accumulates within deep gray matter (DGM) structures early in the disease course. However, the commonly utilized mean R2* and magnetic susceptibility measures reflect regional iron concentration but not a structure's total iron content. Thus, tissue atrophy could impact mean R2* and magnetic susceptibility estimates. PURPOSE: To demonstrate that both average iron concentration and total iron content need to be reported in order to distinguish between atrophy-related and definite magnetic susceptibility changes...
December 4, 2018: Journal of Magnetic Resonance Imaging: JMRI
A Vallard, P Diao, M-A Garcia, G Pigné, N Vial, F Forest, M Peoc'h, J Langrand-Escure, N Magné
PURPOSE: There is paucity of data on rectal cancer with uncommon histologic types. The objective was to describe managements of care and outcomes in patients with rectal cancer of histologic types other than adenocarcinoma. MATERIAL AND METHODS: This monoinstitutional retrospective study included all patients with rectal cancer undergoing rectal radiotherapy. RESULTS: From 2004 to 2015, 744 patients were treated for rectal cancer, and ten had a histologic type other than adenocarcinoma...
November 30, 2018: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
Filippo Parolini, Giovanni Boroni, Susanna Milianti, Luca Tonegatti, Andrea Armellini, Miguel Garcia Magne, Pierluigi Pedersini, Fabio Torri, Paolo Orizio, Stefano Benvenuti, Daniela Maria De Previde Prato, Daniele Alberti
INTRODUCTION: Biliary atresia (BA) represents the leading indication for liver transplantation in childhood. Only few studies reported the outcome of patients who survived more than 20 years on their native liver, and up to date there are no Italian data available. We reported our 40-year single centre experience with long-term follow-up of BA patients. MATERIALS AND METHODS: All consecutive patients who underwent Kasai portoenterostomy (KPE) for BA managed at our Institution between 1975 and 1996 were retrospectively reviewed...
November 6, 2018: Journal of Pediatric Surgery
Tess S Fotidzis, Heechun Moon, Jessica R Steele, Cyrille L Magne
Recent evidence suggests the existence of shared neural resources for rhythm processing in language and music. Such overlaps could be the basis of the facilitating effect of regular musical rhythm on spoken word processing previously reported for typical children and adults, as well as adults with Parkinson's disease and children with developmental language disorders. The present study builds upon these previous findings by examining whether non-linguistic rhythmic priming also influences visual word processing, and the extent to which such cross-modal priming effect of rhythm is related to individual differences in musical aptitude and reading skills...
November 29, 2018: Brain Sciences
Anouar Fanidi, Robert Carreras-Torres, Tricia L Larose, Jian-Min Yuan, Victoria L Stevens, Stephanie J Weinstein, Demetrius Albanes, Ross Prentice, Mary Pettinger, Qiuyin Cai, William J Blot, Alan A Arslan, Anne Zeleniuch-Jacquotte, Marjorie L McCullough, Loic Le Marchand, Lynne R Wilkens, Christopher A Haiman, Xuehong Zhang, Meir J Stampfer, Stephanie A Smith-Warner, Edward Giovannucci, Graham G Giles, Allison M Hodge, Gianluca Severi, Mikael Johansson, Kjell Grankvist, Arnulf Langhammer, Ben M Brumpton, Renwei Wang, Yu-Tang Gao, Ulrika Ericson, Stig Egil Bojesen, Susanne M Arnold, Woon-Puay Koh, Xiao-Ou Shu, Yong-Bing Xiang, Honglan Li, Wei Zheng, Qing Lan, Kala Visvanathan, Judith Hoffman-Bolton, Per Magne Ueland, Øivind Midttun, Neil E Caporaso, Mark Purdue, Neal D Freedman, Julie E Buring, I-Min Lee, Howard D Sesso, J Michael Gaziano, Jonas Manjer, Caroline L Relton, Rayjean J Hung, Chris I Amos, Mattias Johansson, Paul Brennan
Vitamin B supplementation can have side effects for human health, including cancer risk. We aimed to elucidate the role of vitamin B12 in lung cancer aetiology via direct measurements of pre-diagnostic circulating vitamin B12 concentrations in a nested case-control study, complemented with a Mendelian randomization (MR) approach in an independent case-control sample. We used pre-diagnostic biomarker data from 5,183 case-control pairs nested within 20 prospective cohorts, and genetic data from 29,266 cases and 56,450 controls...
November 29, 2018: International Journal of Cancer. Journal International du Cancer
Jon Magne Letnes, Håvard Dalen, Elisabeth K Vesterbekkmo, Ulrik Wisløff, Bjarne M Nes
Aims: The majority of previous research on the association between cardiorespiratory fitness (CRF) and cardiovascular disease (CVD) is based on indirect assessment of CRF in clinically referred predominantly male populations. Therefore, our aim was to examine the associations between VO2peak measured by the gold-standard method of cardiopulmonary exercise testing and fatal and non-fatal coronary heart disease (CHD) in a healthy and fit population. Methods and results: Data on VO2peak from 4527 adults (51% women) with no previous history of cardiovascular or lung disease, cancer, and hypertension or use of antihypertensive medications participating in a large population-based health-study (The HUNT3 Study), were linked to hospital registries and the cause of death registry...
November 29, 2018: European Heart Journal
Jessica Morel, Augustin Pirvu, Amandine Elie, Nicolas Gallet, Jean Luc Magne, Rafaëlle Spear
OBJECTIVE: The aim of this study is to report long-term functional results following cervical rib (CR) resection for thoracic outlet syndrome (TOS). METHODS: This monocentric study included all cases of resection of CR for TOS performed between January 2004 and December 2016. Data were retrospectively collected from the hospital electronic database including pre-operative symptoms and the evaluation of occupational well-being, intraoperative data, and early clinical evaluation and occupational well-being during the post-operative period...
November 23, 2018: Annals of Vascular Surgery
Giovanni Oriolo, Lison Huet, Sandra Dexpert, Cédric Beau, Damien Forestier, Patrick Ledaguenel, Eric Magne, Rocío Martin-Santos, Lucile Capuron
Obesity is a major public health burden associated with neuropsychiatric comorbidities leading to social and occupational impairment. Given the growing prevalence of both obesity and mental disorders worldwide, understanding the risk factors of obesity-related neuropsychiatric comorbidities is crucial to develop preventive strategies and individualized treatments. Recent findings suggest that adiposity-driven inflammation contributes to neuropsychiatric comorbidities in obesity. However, not all obese subjects afflicted with chronic inflammation develop neuropsychiatric symptoms, suggesting additional risk factors...
November 23, 2018: Brain, Behavior, and Immunity
Young Il Yoon, Shin-Woo Ha, Hak Jong Lee
BACKGROUND: Interest in an ultrasound-mediated delivery system for effective T1 -MRI of prostate cancer without adverse effects has steadily increased. PURPOSE: To develop an ultrasound-responsive dual-modal ultrasound (US)/T1 -MRI contrast agent for efficient diagnosis of prostate cancer cells overexpressing prostate-specific membrane antigen (PSMA) and assess their potential. STUDY TYPE: In vitro. SUBJECTS: Two prostate cancer cell lines...
December 2018: Journal of Magnetic Resonance Imaging: JMRI
Ling Zhu, Jingbo Wang, Huimin Shi, Xiaofeng Tao
BACKGROUND: Differential diagnosis of the mucosa-associated lymphoid tissue lymphoma (MALToma) and tumor-like benign lymphoepithelial lesion (BLEL) in the parotid gland is difficult. PURPOSE: To distinguish MALToma and BLEL with multimodality MRI including hydrogenproton magnetic resonance spectroscopy (1 H-MRS), diffusion-weighted imaging (DWI-MR), and dynamic contrast-enhanced (DCE-MR), and evaluate each sequence. STUDY TYPE: Retrospective...
November 26, 2018: Journal of Magnetic Resonance Imaging: JMRI
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