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https://www.readbyqxmd.com/read/30228856/-tribulus-terrestris-protects-against-male-reproductive-damage-induced-by-cyclophosphamide-in-mice
#1
Natasha Frasson Pavin, Aryele Pinto Izaguirry, Melina Bucco Soares, Cristiano Chiapinotto Spiazzi, Andreas Sebastian Loureiro Mendez, Fábio Gallas Leivas, Daniela Dos Santos Brum, Francielli Weber Santos Cibin
Tribulus terrestris (TT) has been considered as a potential stimulator of testosterone production, which has been related with steroidal saponins prevailing in this plant. Cyclophosphamide (CP) is the most commonly used anticancer and immunosuppressant drug, which causes several toxic effects, especially on the reproductive system. Patients who need to use CP therapy exhibit reduced fertility or infertility, which impacts both physically and emotionally on the decision to use this drug, especially among young men...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/30116303/best-practice-in-the-diagnosis-and-treatment-of-varicocele-in-children-and-adolescents
#2
REVIEW
Matthew R Macey, Ryan C Owen, Sherry S Ross, R Matthew Coward
A varicocele is an abnormal dilation of the pampiniform plexus of veins in the scrotum which begins at puberty in approximately 15% of males. Although common in the general population and often asymptomatic, varicoceles are associated with gonadal dysfunction including testicular atrophy, infertility, and hypogonadism in a subset of men diagnosed later in life. Because of the high prevalence and uncertain pathogenesis, definitive management guidelines for varicoceles diagnosed in the pediatric and adolescent population remain poorly defined...
September 2018: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/30019500/alcohol-intake-and-semen-variables-cross-sectional-analysis-of-a-prospective-cohort-study-of-men-referring-to-an-italian-fertility-clinic
#3
E Ricci, S Noli, S Ferrari, I La Vecchia, S Cipriani, V De Cosmi, E Somigliana, F Parazzini
BACKGROUND: The association between alcohol intake and male reproductive function is still controversial. In the frame of a prospective cohort study, designed to investigate the relation between life style and fertility, we performed a cross-sectional analysis of semen quality. METHODS: Men of subfertile couples, referring to an Italian Infertility Unit and eligible for assisted reproductive techniques (ARTs), were asked about their lifestyle: BMI, smoking, caffeine intake, occupational and leisure physical activity (PA) and alcohol intake in the last year before ART procedure...
July 18, 2018: Andrology
https://www.readbyqxmd.com/read/29794946/semen-quality-in-chinese-college-students-associations-with-depression-and-physical-activity-in-a-cross-sectional-study
#4
Peng Zou, Xiaogang Wang, Lei Sun, Qing Chen, Huan Yang, Niya Zhou, Hongqiang Chen, Guowei Zhang, Xi Ling, Zhi Wang, Jianfang Gao, Min Mo, Linping Huang, Kaige Peng, Sheng Chen, Zhihong Cui, Jinyi Liu, Lin Ao, Jia Cao
OBJECTIVE: Behavioral and psychosocial factors have been associated with a decline of the quality of semen. However, the relationship of depression and physical activity (PA) with semen quality remains unclear. METHODS: Data were obtained from 587 young male Chinese college students in June 2013. Participants completed a questionnaire assessing life-style factors, the Zung self-rated depression scale, and three items related to PA. They underwent a physical examination and provided a semen sample and a blood sample for reproductive hormones (testosterone, estrogen, progesterone, follicle-stimulating hormone, luteinizing hormone, and prolactin)...
July 2018: Psychosomatic Medicine
https://www.readbyqxmd.com/read/29774489/the-role-of-lifestyle-in-male-infertility-diet-physical-activity-and-body-habitus
#5
REVIEW
Russell P Hayden, Ryan Flannigan, Peter N Schlegel
PURPOSE OF REVIEW: Increasing attention to primary and secondary prevention of male infertility through modifiable lifestyle factors has gained traction amongst both patients and infertility specialists. In this review, the available evidence of modifiable lifestyle choices, specifically diet, physical activity, and body habitus, are evaluated. RECENT FINDINGS: Studies examining diet, exercise/physical activity, and body habitus are characterized by conflicting conclusions, difficult confounders, and imperfect end points to judge male reproductive potential...
May 17, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29370626/re-associations-between-physical-activity-and-semen-quality-in-young-healthy-men
#6
Craig Niederberger
No abstract text is available yet for this article.
August 2017: Journal of Urology
https://www.readbyqxmd.com/read/29193350/curcumin-nanomicelle-improves-semen-parameters-oxidative-stress-inflammatory-biomarkers-and-reproductive-hormones-in-infertile-men-a-randomized-clinical-trial
#7
RANDOMIZED CONTROLLED TRIAL
Fatemeh Alizadeh, Maryam Javadi, Ali Akbar Karami, Fereshteh Gholaminejad, Maria Kavianpour, Hossein Khadem Haghighian
At least 50% of infertile couple's problems are related to male factor infertility. This Randomized, Double-Blind, Placebo-Controlled Clinical Trial conducted in Urology unit of Infertility Clinic on 60 infertile men. Patients were randomly assigned to one of intervention and placebo (n = 30) groups. Finally, 28 subjects in each group completed the study. Participants in the intervention group took daily 80 mg curcumin nanomicelle and those in the placebo group took daily placebo for 10 weeks. Semen analysis, anthropometric, physical activity assessments, total antioxidant capacity, malondialdehyde, inflammatory factors, and reproductive hormones were measured at the baseline and at the end of the study...
March 2018: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28868837/physically-active-men-show-better-semen-parameters-than-their-sedentary-counterparts
#8
Paula C Lalinde-Acevedo, B Jose Manuel Mayorga-Torres, Ashok Agarwal, Stefan S du Plessis, Gulfam Ahmad, Ángela P Cadavid, Walter D Cardona Maya
Background: The quality of semen depends upon several factors such as environment, life style, physical activity, age, and occupation. The aim of this study was to analyze and compare the conventional and functional semen parameters in men practicing vigorous physical activity to those of sedentary men. MATERIALS AND METHODS: In this descriptive cross-sectional study, semen samples of 17 physically active men and 15 sedentary men were collected for analysis. Semen analysis was performed according to the World Health Organization (WHO) guidelines, while functional parameters were evaluated by flow cytometry...
October 2017: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/28653246/allergy-and-sexual-behaviours-an-update
#9
REVIEW
Marco Caminati, Veronica Giorgis, Boaz Palterer, Francesca Racca, Chiara Salvottini, Oliviero Rossi
The exact prevalence of hypersensitivity reactions related to sexual behaviours is not known; however, they heavily impact on the quality of life and of sex life of affected patients. In fact, not only common respiratory and skin allergies, such as asthma, rhinitis, urticaria and atopic dermatitis, but also food and drug allergy have been found to negatively affect the quality of sex life. Allergic diseases impact on the sexual function in both physical and psychological ways, representing one of the main complaints of a considerable proportion of patients...
June 26, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/27919439/associations-between-physical-activity-and-semen-quality-in-young-healthy-men
#10
Paweł Jóźków, Marek Mędraś, Felicja Lwow, Aleksandra Zagrodna, Małgorzata Słowińska-Lisowska
OBJECTIVE: To evaluate whether the level of everyday physical activity is associated with semen quality in young men. DESIGN: Cross-sectional study. SETTING: Universities, clubs, and societies. PATIENT(S): Young healthy men (aged 18-35 years) with unknown fertility (n = 177). INTERVENTIONS(S): Collection of data on medical history, lifestyle factors (physical activity, nutrition, addictions), and environmental threats (exposure of gonads to cellular phones, laptops)...
February 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/27645515/the-impact-of-intense-exercise-on-semen-quality
#11
REVIEW
Paweł Jóźków, Marco Rossato
With expanding knowledge on the health benefits of exercise, there is an increasing demand for information on the andrological consequences of participating in sports. These consequences are especially important in the context of infertility problems worldwide. The so-called "male factor" is reported in up to 50% of couples having trouble with conception. The answer to the question, "Is physical activity good for male reproductive health?" is not straightforward. A number of studies have suggested that significant changes in semen parameters may occur due to sports training of certain types, intensities, and durations...
May 2017: American Journal of Men's Health
https://www.readbyqxmd.com/read/27501721/is-sedentary-lifestyle-associated-with-testicular-function-a-cross-sectional-study-of-1-210-men
#12
Lærke Priskorn, Tina Kold Jensen, Anne Kirstine Bang, Loa Nordkap, Ulla Nordström Joensen, Tina Harmer Lassen, Inge Ahlmann Olesen, Shanna H Swan, Niels E Skakkebaek, Niels Jørgensen
Based on cross-sectional data on 1,210 healthy young Danish men, we investigated whether sedentary lifestyle was associated with testicular function (semen quality and reproductive hormones) independent of physical activity. The men were invited to participate in the study between 2008 and 2012, when they attended a compulsory medical examination to determine their fitness for military service. Information on sedentary behavior (television watching and computer time) and physical activity was obtained by questionnaire...
August 15, 2016: American Journal of Epidemiology
https://www.readbyqxmd.com/read/27171363/sexual-function-in-male-long-term-survivors-of-childhood-acute-lymphoblastic-leukemia
#13
Anu Haavisto, Markus Henriksson, Risto Heikkinen, Leena-Riitta Puukko-Viertomies, Kirsi Jahnukainen
BACKGROUND: Infertility, poor semen quality, and gonadal dysfunction are well recognized long-term sequelae in male survivors of childhood acute lymphoblastic leukemia (ALL). However, few studies have investigated adult sexual functioning in these survivors. METHODS: The authors studied 52 male survivors of childhood ALL at a median age of 28.5 years (range, 25-38 years) ≥ 10 years after diagnosis. In addition, 56 men without a history of cancer were recruited for an age-matched control group...
July 15, 2016: Cancer
https://www.readbyqxmd.com/read/27030583/exposure-to-power-frequency-magnetic-fields-and-the-risk-of-infertility-and-adverse-pregnancy-outcomes-update-on-the-human-evidence-and-recommendations-for-future-study-designs
#14
REVIEW
Ryan C Lewis, Russ Hauser, Andrew D Maynard, Richard L Neitzel, Lu Wang, Robert Kavet, John D Meeker
Infertility and adverse pregnancy outcomes are significant public health concerns with global prevalence. Over the past 35 years, research has addressed whether exposure to power-frequency magnetic fields is one of the etiologic factors attributed to these conditions. However, no apparent authoritative reviews on this topic have been published in the peer-reviewed literature for nearly 15 years. This review provides an overview and critical analysis of human studies that were published in the peer-reviewed literature between 2002 and July 2015...
2016: Journal of Toxicology and Environmental Health. Part B, Critical Reviews
https://www.readbyqxmd.com/read/26284990/physical-activity-exercise-and-mammalian-testis-function-emerging-preclinical-protein-biomarker-and-integrative-biology-insights
#15
REVIEW
Mariana Gomes, Maria João Freitas, Margarida Fardilha
Exercise and physical activity have long been recognized for health promotion and to delay the onset of many pathological situations such as diabetes and cancers. Still, there appears to be an upper limit on the beneficial health effects regarding intensity and frequency of exercise training. In humans, the effect of exercise training in the male reproductive system has been studied mainly through the analysis of semen quality parameters, with inconsistent results. Less is known on molecular biomarkers of exercise-related changes in testis at the protein/proteome level...
September 2015: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/26222070/the-5-amp-activated-protein-kinase-ampk-is-involved-in-the-augmentation-of-antioxidant-defenses-in-cryopreserved-chicken-sperm
#16
Thi Mong Diep Nguyen, François Seigneurin, Pascal Froment, Yves Combarnous, Elisabeth Blesbois
Semen cryopreservation is a unique tool for the management of animal genetic diversity. However, the freeze-thaw process causes biochemical and physical alterations which make difficult the restoration of sperm energy-dependent functions needed for fertilization. 5'-AMP activated protein kinase (AMPK) is a key sensor and regulator of intracellular energy metabolism. Mitochondria functions are known to be severely affected during sperm cryopreservation with deleterious oxidative and peroxidative effects leading to cell integrity and functions damages...
2015: PloS One
https://www.readbyqxmd.com/read/26088243/re-physical-activity-is-not-related-to-semen-quality-in-young-healthy-men
#17
COMMENT
Craig Niederberger
No abstract text is available yet for this article.
July 2015: Journal of Urology
https://www.readbyqxmd.com/read/26051095/randomized-triple-blind-placebo-controlled-clinical-trial-examining-the-effects-of-alpha-lipoic-acid-supplement-on-the-spermatogram-and-seminal-oxidative-stress-in-infertile-men
#18
RANDOMIZED CONTROLLED TRIAL
Hossein Khadem Haghighian, Fatemeh Haidari, Javad Mohammadi-Asl, Mohammadreza Dadfar
OBJECTIVE: To evaluate effects of supplementation with alpha-lipoic acid (ALA) on the spermatogram and seminal oxidative stress biomarkers. DESIGN: Randomized, triple-blind, placebo-controlled clinical trial. SETTING: Infertility clinic. PATIENT(S): Infertile men. INTERVENTION(S): ALA (600 mg) or placebo for 12 weeks. MAIN OUTCOME MEASURE(S): Semen analysis, anthropometric, dietary, and physical activity assessments, total antioxidant capacity, and malondialdehyde...
August 2015: Fertility and Sterility
https://www.readbyqxmd.com/read/25999214/physical-activity-fatness-educational-level-and-snuff-consumption-as-determinants-of-semen-quality-findings-of-the-actiart-study
#19
Triin Pärn, Raúl Grau Ruiz, Theodora Kunovac Kallak, Jonatan R Ruiz, Eva Davey, Julius Hreinsson, Kjell Wånggren, Andres Salumets, Michael Sjöström, Anneli Stavreus-Evers, Francisco B Ortega, Signe Altmäe
In this study, the association between physical activity and other potential determinants, objectively measured by accelerometry, was examined. Sixty-two men attending an infertility clinic participated in the study. Obese men (body mass index ≥ 30) and those with a waist circumference 102 cm or more had lower semen volume than the other men (P < 0.05). Higher values in sperm parameters were observed in participants who completed university studies and those who did not consume snuff, compared with the other participants (P < 0...
July 2015: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/25986209/sexual-function-in-adult-patients-with-classic-bladder-exstrophy-a-multicenter-study
#20
MULTICENTER STUDY
Weon Park, Nadine Zwink, Wolfgang H Rösch, Eberhard Schmiedeke, Raimund Stein, Dominik Schmidt, Meinolf Noeker, Ekkehart Jenetzky, Heiko Reutter, Anne-Karoline Ebert
BACKGROUND: The bladder exstrophy-epispadias complex (BEEC) comprises a spectrum of congenital anomalies that represents the severe end of urorectal malformations, and has a profound impact on continence as well as sexual and renal functions. OBJECTIVE: The relation between severity of BEEC and its associated functional impairments, on one hand, and the resulting restrictions in quality of life and potential psychopathology determine the patients' outcome. It is important for improving further outcome to identify BEEC-related sources of distress in the long term...
June 2015: Journal of Pediatric Urology
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