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Subcapsular cataract

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https://www.readbyqxmd.com/read/28291554/implantation-of-posterior-chamber-phakic-intraocular-lens-for-myopia-and-hyperopia%C3%A2-%C3%A2-long-term-clinical-outcomes
#1
H Kocová, E Vlková, L Michalcová, O Motyka
PURPOSE: To evaluate long-term refractive outcomes of implantable collamer lens (ICL) implantation and late postoperative complications. METHODS: We assessed outcomes of patients who underwent ICL implantation (type ICM V4 for myopia, ICH V3 for hyperopia, TICM V4 for astigmatism) in our department between 1998 and 2013. It comprised 62 eyes (40 myopic and 22 hyperopic). The average follow-up period was 10.5 years. We evaluated: uncorrected and best-corrected visual acuity (UCVA and BCVA), spherical equivalent (SE), ICL vault, endothelial cell density and late postoperative complications...
March 10, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28182590/lens-opacity-and-hydrogen-sulfide-in-a-new-zealand-geothermal-area
#2
Michael N Bates, Ian L Bailey, Robert B DiMartino, Karl Pope, Julian Crane, Nick Garrett
PURPOSE: Hydrogen sulfide (H2S) is a highly toxic gas with well-established, acute irritation effects on the eye. The population of Rotorua, New Zealand, sited on an active geothermal field, has some of the highest ambient H2S exposures in the world. Evidence from ecological studies in Rotorua has suggested that H2S is associated with cataract. The purpose of the present study was, using more detailed exposure characterization, clinical examinations, and anterior eye photography, to more directly investigate this previously reported association...
January 11, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28128429/-neurofibromatosis-type-2-in-childhood-a-clinical-characterization
#3
C M Hinojosa-Mateo, J A Reche-Sainz, A Hernandez-Nunez, M Ramos-Lopez, A Arpa-Fernandez, D Natera-de Benito
INTRODUCTION: Neurofibromatosis type 2 (NF2) is a dominantly inherited neuroectodermal syndrome that predispose to the development of tumors of the central and peripheral nervous system. Additional features include eye and skin abnormalities. CASE REPORT: A 12-year old male with diagnosis of MF2 according to Baser et al and presentation in childhood was included. A comprehensive bibliographic review of evolution of the diagnostic criteria for NF2 in children was performed...
February 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/27986963/eye-lens-radiation-exposure-in-greek-interventional-cardiology-article
#4
Zoi Thrapsanioti, Panagiotis Askounis, Ioannis Datseris, Ramza Anastasia Diamanti, Miltiadis Papathanasiou, Eleftheria Carinou
The lens of the eye is one of the radiosensitive tissues of the human body; if exposed to ionizing radiation can develop radiation-induced cataract at early ages. This study was held in Greece and included 44 Interventional Cardiologists (ICs) and an unexposed to radiation control group of 22 persons. Of the note, 26 ICs and the unexposed individuals underwent special eye examinations. The detected lens opacities were classified according to LOCS III protocol. Additionally, the lens doses of the ICs were measured using eye lens dosemeters...
December 15, 2016: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/27979014/inhaled-corticosteroids-ocular-safety-and-the-hypothalamic-pituitary-adrenal-axis
#5
Warner W Carr, Stanley J Szefler
BACKGROUND: Inhaled corticosteroids (ICSs) effectively deliver corticosteroids to target sites in the lungs and reduce systemic effects compared with oral corticosteroids, but long-term systemic exposure from inhaled corticosteroids remains a concern. OBJECTIVE: To discuss ICS systemic effects on the eye and the hypothalamic-pituitary-adrenal (HPA) axis. METHODS: Relevant publications were used to augment discussion. RESULTS: The most common adverse effects of exogenous corticosteroids on the eye are secondary open-angle glaucoma and posterior subcapsular cataracts...
December 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27936471/prevalence-of-lens-opacities-in-adult-chinese-americans-the-chinese-american-eye-study-ches
#6
Rohit Varma, Jie Sun, Mina Torres, Shuang Wu, Chunyi Hsu, Stanley Paul Azen, Roberta McKean-Cowdin
Purpose: We determined the age- and sex-specific prevalence of posterior subcapsular (PSC), nuclear, cortical, and mixed lens opacities in a population-based sample of Chinese-American adults. Methods: A population-based sample of Chinese-Americans 50 years and older, from 10 census tracts in Monterey Park, CA, USA, underwent a detailed interview and a comprehensive clinical examination that included assessment of different types of lens opacities by the slit-lamp-based Lens Opacities Classification System II (LOCS II)...
December 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27930432/retinal-findings-in-a-case-of-presumed-cutis-marmorata-telangiectatica-congenita
#7
Eman A Taleb, Manish P Nagpal, Navneet S Mehrotra, Kalyani Bhatt
PURPOSES: To correlate the clinical picture and fundus fluorescein angiography findings in case of presumed cutis marmorata telangiectatica congenita. METHODS: A 41-year-old woman with presumed cutis marmorata telangiectatica congenita who is a known case of hypothyroidism for the last 6 years and has bilateral peripheral retinal vascular abnormalities, peripheral retinal nonperfusion on fluorescein angiography and bilateral optic disk drusen. RESULT: A patient presented with blurring of vision in both eyes for last 6 months...
December 7, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27899085/oestradiol-levels-and-superoxide-dismutase-activity-in-age-related-cataract-a-case-control-study
#8
Dragana Škiljić, Staffan Nilsson, Anne Petersen, Jan-Olof Karlsson, Anders Behndig, Lada Kalaboukhova, Madeleine Zetterberg
BACKGROUND: It has been suggested that the higher prevalence of cataract in women is caused by a withdrawal effect of oestrogen at menopause. In vitro studies have demonstrated protection of serum oestradiol (E2) against oxidative stress through upregulation of antioxidant enzymes, including superoxide dismutase (SOD). The purpose of the present study was to investigate E2 levels and SOD erythrocyte activity in patients with age-related cataract. METHODS: The studied subjects consisted of 103 patients with age-related cataract and 22 controls...
November 29, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27881591/vernal-keratoconjunctivitis-culmination-of-management-using-immunosuppression-surgical-and-prosthetic-therapy-over-quarter-century
#9
Shilpa Das, Anand S Pasari, Virender S Sangwan
A 22-year-old male patient presented in 1988 with active vernal keratoconjunctivitis. He was treated with topical mast cell stabilisers and corticosteroids. Chronic inflammation despite topical treatment necessitated oral immunosuppressants. Active disease came under control with this; however, the patient gradually developed limbal stem cell deficiency. He underwent bilateral pannus resection with amniotic membrane transplantation that resulted in improved ocular surface. In 2007, patient was found to have significant bilateral posterior subcapsular cataracts and underwent bilateral cataract surgery with intraocular lens implantation with good visual outcome...
November 23, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27866070/spontaneous-rupture-of-chorioretinal-coloboma-in-an-8-year-old-child-is-treated-by-temporal-fascia-graft
#10
Hélène Chan, Marie-Noëlle Delyfer, Jacmine Pechmeja, Clémence Andrèbe, Audrey-Elodie Mercier, Cyril Dutheil, Jean-François Korobelnik, Clément Paya
We report the rare case of an 8-year-old boy with spontaneous scleral perforation secondary to an isolated congenital chorioretinal coloboma. Visual acuity was 20/200 and examination revealed severe hypotony with subcapsular cataract, complete exudative retinal detachment, hypotonous optic nerve swelling, and hypotony retinal fold. In the temporal periphery, there was a chorioretinal coloboma with a central full-thickness defect. The scleral defect was successfully treated with an autologous temporalis fascia graft...
November 16, 2016: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/27843234/progressive-keratoconus-retinal-detachment-and-intracorneal-silicone-oil-with-obsessive-compulsive-eye-rubbing
#11
Kartik Panikkar, George Manayath, Revathi Rajaraman, Veerappan Saravanan
An 18-year-old boy with an obsessive-compulsive disorder of eye rubbing presented with forme fruste keratoconus (KC) and posterior subcapsular cataracts. After evaluation, he underwent phacoemulsification in his left eye with intraocular lens implantation. The aggressive eye rubbing, however, aggravated the rapid progression to established KC, and further acute corneal hydrops within 3 months. Within the next 3 months, the eye rubbing precipitated rhegmatogenous retinal detachments (RDs) in both eyes. Furthermore, after undergoing a combined cataract and RD surgery with belt buckling and silicone oil endotamponade in his right eye, the repeated eye rubbing caused extrusion of the implanted silicone oil into the subconjunctival space and within the corneal stroma...
September 2016: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/27801692/histopathology-of-subcapsular-cataract-in-a-patient-with-atopic-dermatitis
#12
Daisy Yao Shu, Keith Ong, Frank J Lovicu
PURPOSE: To report the histopathological features of anterior subcapsular cataract associated with atopic dermatitis. CASE REPORT: A 29-year-old man with atopic dermatitis presented with bilateral anterior subcapsular cataract. After routine cataract surgery, the anterior subcapsular cataractous tissue was obtained as an anterior capsulorhexis flap and prepared as a wholemount for histological analysis. The wholemount consisted of a well-demarcated central grayish-white plaque surrounded by transparent capsule, corroborating the slit-lamp biomicroscopic appearance...
February 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27738538/neurofibromatosis-type-2-presenting-with-oculomotor-ophthalmoplegia-and-distal-myopathy
#13
Jessica Mani Penny Tevaraj, Evelyn Tai Li Min, Raja Azmi Mohd Noor, Azhany Yaakub, Wan Hazabbah Wan Hitam
Neurofibromatosis type 2 usually presents with bilateral acoustic schwannomas. We highlight the rare presentation of neurofibromatosis initially involving third nerve. A 23-year-old Malay female presented with left eye drooping of the upper lid and limitation of upward movement for 8 years. It was associated with right-sided body weakness, change in voice, and hearing disturbance in the right ear for the past 2 years. On examination, there was mild ptosis and limitation of movement superiorly in the left eye...
2016: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/27704140/rhoa-rock-signaling-regulates-tgf%C3%AE-induced-epithelial-mesenchymal-transition-of-lens-epithelial-cells-through-mrtf-a
#14
Anna Korol, Aftab Taiyab, Judith A West-Mays
Transforming growth factor (TGF)-β-induced epithelial-mesenchymal transition (EMT) leads to the formation of ocular fibrotic pathologies, such as anterior subcapsular cataract and posterior capsule opacification. Remodeling of the actin cytoskeleton, mediated by the Rho family of GTPases, plays a key role in EMT, however, how actin dynamics affect downstream markers of EMT has not been fully determined. Our previous work suggests that myocardin related transcription factor A (MRTF-A), an actin-binding protein, might be an important mediator of TGFβ-induced EMT in lens epithelial cells...
September 29, 2016: Molecular Medicine
https://www.readbyqxmd.com/read/27703255/effects-of-histone-acetylation-on-superoxide-dismutase-1-gene-expression-in-the-pathogenesis-of-senile-cataract
#15
Xianfang Rong, Xiaodi Qiu, Yongxiang Jiang, Dan Li, Jie Xu, Yinglei Zhang, Yi Lu
Histone acetylation plays key roles in gene expression, but its effects on superoxide dismutase 1 (SOD1) expression in senile cataract remains unknown. To address this problem, the study was to investigate the influence of histone acetylation on SOD1 expression and its effects in the pathogenesis of senile cataract. Senile cataract was classified into three types-nuclear cataract (NC), cortical cataract (CC), and posterior subcapsular cataract (SC)-using the Lens Opacities Classification System III. In senile cataracts, SOD1 expression decreased significantly...
October 5, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27664702/axial-length-measurement-failure-rates-with-biometers-using-swept-source-optical-coherence-tomography-compared-to-partial-coherence-interferometry-and-optical-low-coherence-interferometry
#16
Colm McAlinden, Qinmei Wang, Rongrong Gao, Weiqi Zhao, Ayong Yu, Yu Li, Yan Guo, Jinhai Huang
PURPOSE: To compare a new swept-source optical coherence tomography (SSOCT)-based biometer (OA-2000) with the IOLMaster v5.4 (partial-coherence interferometry) and Aladdin (optical low-coherence interferometry) biometers in terms of axial length measurement and failure rate in eyes with cataract. DESIGN: Reliability study. METHODS: A total of 377 eyes of 210 patients were scanned with the 3 biometers in a random order. For each biometer, the number of unobtainable axial length measurements was recorded and grouped as per the type and severity of cataract based on the Lens Opacities Classification System III by the same experienced ophthalmologist...
January 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27638315/management-of-traumatic-haemorrhage-in-the-berger-s-space-of-a-4-year-old-child
#17
Stephen Tak-Lun Li, Evan Po-Fat Yiu, Angela Hiu-Yan Wong, John Chun-Ting Yeung, Lester Wang-Hon Yu
We are reporting an unusual case of haemorrhage in the Berger's space after an episode of blunt ocular trauma in an eye of a 4-year-old boy, who enjoyed premorbid normal vision. A secondary posterior subcapsular cataract developed as a complication of the haemorrhage after 6 months of observation. Surgery comprised cataract extraction, removal of a residual retrolenticular haematoma via opening of posterior continuous curvilinear capsulorhexis (CCC), anterior vitrectomy and placement of an intraocular lens...
September 8, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27610257/a-gel-formulation-containing-a-new-recombinant-form-of-manganese-superoxide-dismutase-a-clinical-experience-based-on-compassionate-use-safety-of-a-case-report
#18
Lucia Grumetto, Antonio Del Prete, Giovanni Ortosecco, Antonella Borrelli, Salvatore Del Prete, Aldo Mancini
Background. We report a case of bilateral posterior subcapsular cataracts (PSCs) in a 24-year-old man with an allergic conjunctivitis history caused by a long-term therapy with glucocorticoids. Case Presentation. The patient showed a visual acuity of 9/10 for both eyes. He followed a therapy with ketotifen and bilastine for four years. During the last six months before our evaluation, he was treated with chloramphenicol and betamethasone, interrupted for onset of cataracts and increased intraocular pressure...
2016: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/27608477/early-onset-steroid-induced-posterior-subcapsular-cataract-in-a-patient-with-common-variable-immunodeficiency-case-reports-and-review-of-literature
#19
H Marefat, H Abolhassani, M Ghareje Daghi, G Azizi, A Aghamohammadi
Purpose. To report early onset steroid induced posterior subcapsular cataract in a case of common variable immunodeficiency. Methods. Case report. Results. Here we report a 14-yearold male of steroid induced bilateral posterior subcapsular cataract in a common variable immunodeficiency patient with damaging mutations in Glutathione reductase gene, leading to hypersensitivity of patient to glucocorticoid (GC) products. Conclusions. In order to reduce the ocular side effects of the GCs there are some advisements, including a complete history, regular examination, GC should be prescribed in minimal dosage and minimal course, and as possible GC-sparing drugs should always be considered...
September 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27574177/cataracts-induced-by-neodymium-yttrium-aluminium-garnet-laser-lysis-of-vitreous-floaters
#20
Ellen H Koo, Luis J Haddock, Namita Bhardwaj, Jorge A Fortun
BACKGROUND: Neodymium-yttrium-aluminium-garnet (Nd:YAG) laser vitreolysis has been proposed as a treatment modality for symptomatic vitreous floaters. The purpose of this paper is to report two cases of cataracts associated with posterior capsular compromise, induced by Nd:YAG laser vitreolysis for symptomatic vitreous floaters. METHOD: Case series. RESULTS: Two patients who underwent ND:YAG laser vitreolysis for symptomatic floaters, presented with decline in visual acuity in the treated eye after the laser procedure...
August 29, 2016: British Journal of Ophthalmology
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