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Subcapsular cataract

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https://www.readbyqxmd.com/read/29289688/cataract-development-in-children-with-coats-disease-risk-factors-and-outcome
#1
Alejandra Daruich, Alexandre Matet, Francis L Munier
PURPOSE: To describe the clinical features of cataract during the course of Coats disease and to determine its risk factors and effects on the long-term visual outcome. METHODS: The medical records of consecutive patients with Coats disease followed for at least 2 years were analyzed retrospectively. Ophthalmological examination, ancillary tests, and treatment modalities were reviewed. The time of cataract diagnosis and its management were recorded. Parameters influencing cataract development and final visual outcome were investigated using uni- and multivariate analysis...
December 28, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29243035/systemic-lupus-erythematosus-and-ocular-involvement-an-overview
#2
REVIEW
Rosanna Dammacco
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease of undefined etiology and with remarkably heterogeneous clinical features. Virtually any organ system can be affected, including the eye. SLE-related eye involvement can be diagnosed in approximately one-third of the patients and is usually indicative of disease activity. An early diagnosis and the adoption of suitable therapeutic measures are necessary to prevent sight-threatening consequences, especially in patients with juvenile SLE. Periocular lesions, such as eyelid involvement and orbital inflammation, are relatively rare and, in case of orbital masses, may require a biopsy control...
December 14, 2017: Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/29237667/posterior-capsular-rupture-and-spontaneous-posterior-dislocation-of-lens-following-electrical-injury
#3
Devesh Kumawat, Karthikeya Ramananda, Pranita Sahay, Atul Kumar
Lenticular changes are often seen following electrical injury. We report an unusual case of electrical injury with late spontaneous posterior dislocation of lens nucleus with intact anterior capsule with ruptured posterior capsule in the right eye and anterior subcapsular cataract in the left eye. The right eye was managed with pars plana vitrectomy with cortical matter removal with multipiece intraocular lens insertion in ciliary sulcus. This report adds posterior capsular rupture and posterior dislocation of lens to the usual ocular complications of electrical injury...
December 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29189944/the-ultrastructural-alterations-in-the-lens-capsule-and-epithelium-in-eyes-with-traumatic-white-cataract
#4
Merve Inanc, Kemal Tekin, Yasemin Ozdamar Erol, Mustafa Fevzi Sargon, Mustafa Koc, Ozlem Budakoglu, Pelin Yılmazbas
PURPOSE: To demonstrate the morphological and physiological characteristics of lens epithelial cells (LECs) in patients with traumatic cataract using transmission electron microscopy (TEM) to further understand penetrating ocular injury-induced cataract morphology and epithelial repair mechanisms involved at a cellular level. METHODS: This is a prospective international study. Sixteen eyes of 16 consecutive patients who were diagnosed as traumatic white cataracts following the anterior lens capsule perforation and 13 eyes of 13 patients with idiopathic posterior subcapsular cataract were included to the study...
November 30, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29164235/incidence-progression-and-risk-factors-for-cataract-in-type-2-diabetes
#5
Sangeetha Srinivasan, Rajiv Raman, Gayathri Swaminathan, Suganeswari Ganesan, Vaitheeswaran Kulothungan, Tarun Sharma
Purpose: We report the 4-year incidence, progression, and risk factors of cataract subtypes in type 2 diabetes. Methods: A total of 779 subjects completed baseline and 4-year follow-up. Results: The incidences of nuclear opalescence (NO), nuclear color (NC), cortical cataract (CC), and posterior subcapsular cataract (PSC) were 70%, 55.2%, 25.7%, and 7.3%, respectively. One-step progressions of NO, NC, CC, and PSC were 14.3%, 16.1%, 8.8%, and 8...
November 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29141386/-clinical-characteristics-and-surgical-effect-observation-of-congenital-aniridia-combined-with-cataract
#6
X H Wu, Q Z Cao, Y X Hu, J N Lin, H T Lin, W R Chen, Y Z Liu
Objective: To analyze the clinical manifestations, surgical approaches and postoperative prognosis for the cases of congenital aniridia combined with cataract. Methods: In this retrospective case series, 26 patients diagnosed with congenital aniridia combined with cataract were collected from Zhongshan Ophthalmic Center from February 2002 to August 2016. The Clinical data were collected to analyze the clinical features, surgical approaches and postoperative prognosis. T-test was used for statistical analysis...
November 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29127310/wavefront-aberrations-and-retinal-image-quality-in-different-lenticular-opacity-types-and-densities
#7
Cheng-Zhe Wu, Hua Jin, Zhen-Nv Shen, Ying-Jun Li, Xun Cui
To investigate wavefront aberrations in the entire eye and in the internal optics (lens) and retinal image qualities according to different lenticular opacity types and densities. Forty-one eyes with nuclear cataract, 33 eyes with cortical cataract, and 29 eyes with posterior subcapsular cataract were examined. In each group, wavefront aberrations in the entire eye and in the internal optics and retinal image quality were measured using a raytracing aberrometer. Eyes with cortical cataracts showed significantly higher coma-like aberrations compared to the other two groups in both entire eye and internal optic aberrations (P = 0...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29118503/inadvertent-intralenticular-dexamethasone-implant-1-year-follow-up-and-management
#8
Cagatay Caglar
We report the case of a 72-year-old female who developed macular edema (ME) due to hemicentral retinal vein occlusion in her right eye. A dexamethasone implant was inadvertently injected into the crystalline lens. The patient was followed without repositioning of the dexamethasone implant during the 12 months. Besides, the posterior subcapsular cataract and ME had progressed significantly; hence, cataract extraction and intravitreal ranibizumab injection were performed in the same session. A three-piece intraocular lens was implanted in the sulcus with optic captured, and then intravitreal ranibizumab injection was performed...
September 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29110086/acute-and-chronic-fluid-misdirection-syndrome-pathophysiology-and-treatment
#9
Andrzej Grzybowski, Piotr Kanclerz
PURPOSE: To summarize our current understanding of the specific pathogenic mechanisms of the fluid misdirection syndrome and possible treatment methods. METHODS: We used the PubMed web platform to find relevant studies using the following keywords: infusion misdirection syndrome, aqueous misdirection syndrome, ciliary block, ciliovitreal block, capsular block, intraoperative fluid misdirection, subcapsular fluid entrapment, acute intraoperative rock-hard eye syndrome, positive vitreous pressure glaucoma, and malignant glaucoma...
November 6, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29048240/natural-course-of-posterior-subcapsular-cataract-over-a-short-time-period
#10
Thomas Neumayer, Nino Hirnschall, Michael Georgopoulos, Oliver Findl
Purpose/aim of the study: To observe and analyze the weekly changes in morphology and size of vacuoles, so called Wedl cells, in eyes with posterior subcapsular cataract (PSC). MATERIALS AND METHODS: Thirty-six eyes of 36 patients with pronounced PSC were included in this prospective study. High-resolution retroillumination images were taken, and the changes in size and shape of Wedl cells were analyzed at baseline and at 2 and 4 weeks later using dedicated imaging software. RESULTS: In total, 1087 Wedl cells were observed...
October 19, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29018756/descemet-s-stripping-automated-endothelial-keratoplasty-for-symptomatic-thioridazine-deposits-in-the-cornea
#11
Masoumeh Mohebbi, Hassan Hashemi, Alireza Mahmoudi, Pasha Anvari
The aim of this study was to use Descemet's Stripping-automated Endothelial Keratoplasty (DSAEK) as a novel treatment to remove thioridazine corneal deposits. A 53-year-old female presented with a 3-month history of visual loss and glare. She had been taking thioridazine (100 mg/day for 1 year) for a psychiatric disorder. Dense yellowish-brown deposits had developed in the posterior stroma. Thioridazine was discontinued, and she was switched to fluoxetine. One year after discontinuation of thioridazine, her symptoms and signs did not resolve...
January 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/28991611/effect-of-fixation-stability-during-biometry-measurements-on-refractive-prediction-accuracy-in-highly-myopic-eyes
#12
Xiangjia Zhu, Wenwen He, Yu Du, Yi Lu
PURPOSE: To assess the effect of preoperative biometry fixation stability on postoperative refractive errors in highly myopic cataractous eyes. SETTING: Eye and ENT Hospital of Fudan University, Shanghai, China. DESIGN: Prospective cohort study. METHODS: Eyes of highly myopic patients and emmetropic controls were included. Routine ophthalmologic examinations and measurement of fixation stability in the 63% and 95% bivariate contour ellipse areas (BCEAs) were conducted preoperatively...
September 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28973339/association-between-serum-complement-c3-levels-and-age-related-cataract
#13
Mingxi Shao, Danhui Li, Jisen Teng, Yudong Zhang, Shengjie Li, Wenjun Cao
Purpose: The serum complement component 3 (C3) concentration and clinical characteristics of age-related cataract (ARC) subjects were analyzed to evaluate whether serum C3 levels are correlated with ARC. Methods: A total of 492 ARC patients and 466 normal subjects from the Department of Ophthalmology and Visual Science, Eye and ENT Hospital of Fudan University, Shanghai, China, were consecutively recruited into this study between June 2014 and May 2017. Immunoturbidimetry was used to measure the serum C3 levels...
September 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28917409/methods-for-assessing-forward%C3%A2-and%C3%A2-backward-light-scatter%C3%A2-in%C3%A2-patients-with%C3%A2-cataract
#14
Alja Crnej, Nino Hirnschall, Con Petsoglou, Oliver Findl
PURPOSE: To compare objective methods for assessing backward and forward light scatter and psychophysical tests in patients with cataracts. SETTING: Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom. DESIGN: Prospective case series. METHODS: This study included patients scheduled for cataract surgery. Lens opacities were grouped into predominantly nuclear sclerotic, cortical, posterior subcapsular, and mixed cataracts...
August 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28862736/long-term-results-of-pars-plana-vitrectomy-as-an-anti-inflammatory-therapy-of-pediatric-intermediate-uveitis-resistant-to-standard-medical-treatment
#15
Denisa Darsová, Pavel Pochop, Jana Štěpánková, Dagmar Dotřelová
PURPOSE: To evaluate the efficacy of pars plana vitrectomy (PPV) as an anti-inflammatory therapy in pediatric recurrent intermediate uveitis. METHODS: A retrospective study evaluated the long-term results of PPV indicated for intermediate uveitis with a mean observation period of 10.3 years (range 7-15.6 years) in 6 children (mean age 8 years, range 6-12 years). Pars plana vitrectomy was performed on 10 eyes in the standard manner and was initiated by vitreous sampling for laboratory examination...
August 17, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28834919/a-case-of-neurofibromatosis-type-2-with-unusual-clinical-features
#16
Mohamma Zarei, Parisa Hamzeloui, Ramak Rooipoor, Masoud Aghsaei Fard
PURPOSE: To report a case of a neurofibromatosis Type 2 with unusual clinical features. METHODS: Observational clinical case report. RESULTS: A 22-year-old woman was referred with bilateral blurred vision and macular "scars." Ocular examination revealed bilateral posterior subcapsular and cortical cataract, optic disk swelling, hyperpigmented macular lesions, epiretinal membrane, and macular temporal dragging. Spectral-domain optical coherence tomographic imaging showed bilateral epiretinal membranes, peripapillary nerve fiber layer thickening, and vitreoretinal tractional bands...
August 21, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28831307/changes-in-intraocular-straylight-and-visual-acuity-with-age-in-cataracts-of-different-morphologies
#17
REVIEW
Sonia Gholami, Nicolaas J Reus, Thomas J T P van den Berg
PURPOSE: To investigate the significance of difference in straylight of cataract eyes with different morphologies, as a function of age and visual acuity. METHODS: A literature review to collect relevant papers on straylight, age, and visual acuity of three common cataract morphologies leads to including five eligible papers for the analysis. The effect of morphology was incorporated to categorize straylight dependency on the two variables. We also determined the amount of progression in a cataract group using a control group...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28807717/myofibroblast-transdifferentiation-the-dark-force-in-ocular-wound-healing-and-fibrosis
#18
REVIEW
Daisy Y Shu, Frank J Lovicu
Wound healing is one of the most complex biological processes to occur in life. Repair of tissue following injury involves dynamic interactions between multiple cell types, growth factors, inflammatory mediators and components of the extracellular matrix (ECM). Aberrant and uncontrolled wound healing leads to a non-functional mass of fibrotic tissue. In the eye, fibrotic disease disrupts the normally transparent ocular tissues resulting in irreversible loss of vision. A common feature in fibrotic eye disease is the transdifferentiation of cells into myofibroblasts that can occur through a process known as epithelial-mesenchymal transition (EMT)...
September 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28757693/effect-of-phacoemulsification-on-measurement-of-retinal-nerve-fiber-layer-and-optic-nerve-head-parameters-using-spectral-domain-optical-coherence-tomography
#19
Bhaskar Jha, Reetika Sharma, Murugesan Vanathi, Tushar Agarwal, Talvir Sidhu, Ankit Tomar, Tanuj Dada
PURPOSE: The purpose of this study is to determine the effect of phacoemulsification cataract extraction on measurement of retinal nerve fiber layer and optic nerve head parameters using spectral domain optical coherence tomography. MATERIAL AND METHODS: A prospective, hospital-based study of 100 patients of 40 years of age and above, with no other ocular morbidity except cataract and planned for phacoemulsification with IOL implantation (SN60WF) at a tertiary centre at AIIMS, New Delhi, India...
May 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/28728538/effects-of-cataract-opacity-and-surgery-on-sleep-quality
#20
Aya Kokune-Takahashi, Masahiko Ayaki, Kazuo Tsubota, Kazuno Negishi
This study aimed to identify the type of cataract opacity associated with subjective sleep quality for cataract patients. A total of 180 consecutive patients (average age 74.2 years) underwent cataract surgery with implantation of an ultraviolet-blocking or blue light-blocking intraocular lens. The participants' subjective sleep quality was evaluated using the Pittsburgh sleep quality index (PSQI) before and at 2 months after surgery. Patients were divided into two groups for analysis: normal sleepers (preoperative PSQI ≤5) and poor sleepers (preoperative PSQI ≥6)...
August 29, 2017: Rejuvenation Research
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