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Omega_3 AND Cancer Related Fatigue

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https://www.readbyqxmd.com/read/29915949/dietary-supplements-and-fatigue-in-patients-with-breast-cancer-a-systematic-review
#1
REVIEW
Paula Tâmara Vieira Teixeira Pereira, Andréa Dias Reis, Renata Rodrigues Diniz, Franciléia Andrade Lima, Richard Diego Leite, Mayara Cristina Pinto da Silva, Rosane Nassar Meireles Guerra, Érica Brandão de Moraes Vieira, João Batista Santos Garcia
PURPOSE: Cancer-related fatigue (CRF) is defined as a distressing, persistent, and subjective sense of physical or emotional and/or cognitive exhaustion. The treatment of CRF includes pharmacological and non-pharmacological therapies; dietary strategies with promising results have also been used. This study aimed to identify dietary supplements that improve fatigue in patients with breast cancer. METHODS: A systematic review of the literature was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement...
June 18, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29321047/effects-of-concentrated-long-chain-omega-3-polyunsaturated-fatty-acid-supplementation-before-radical-prostatectomy-on-prostate-cancer-proliferation-inflammation-and-quality-of-life-study-protocol-for-a-phase-iib-randomized-double-blind-placebo-controlled-trial
#2
Marie-Hélène Guertin, Karine Robitaille, Jean-François Pelletier, Thierry Duchesne, Pierre Julien, Josée Savard, Isabelle Bairati, Vincent Fradet
BACKGROUND: Prostate cancer is the most commonly diagnosed cancer in north-American men. Few dietary or lifestyle interventions have been tested to prevent prostate cancer progression. Omega-3 fatty acid supplementation represents a promising intervention for prostate cancer patients. The aim of the study is to evaluate the effects of long-chain omega-3 polyunsaturated fatty acids (LCn3), more precisely eicosapentaenoic acid monoacylglyceride (MAG-EPA) supplementation, on prostate cancer proliferation, inflammation mediators and quality of life among men who will undergo radical prostatectomy...
January 10, 2018: BMC Cancer
https://www.readbyqxmd.com/read/24739260/the-muscle-mass-omega-3-diet-exercise-and-lifestyle-model-study-a-randomised-controlled-trial-for-women-who-have-completed-breast-cancer-treatment
#3
RANDOMIZED CONTROLLED TRIAL
Cameron McDonald, Judy Bauer, Sandra Capra, Joseph Coll
BACKGROUND: Loss of lean body mass (LBM) is a common occurrence after treatment for breast cancer and is related to deleterious metabolic health outcomes [Clin Oncol, 22(4):281-288, 2010; Appl Physiol Nutr Metab, 34(5):950-956, 2009]. The aim of this research is to determine the effectiveness of long chain omega-3 fatty acids (LCn-3s) and exercise training alone, or in combination, in addressing LBM loss in breast cancer survivors. METHODS/DESIGN: A total of 153 women who have completed treatment for breast cancer in the last 12 months, with a Body Mass Index (BMI) of 20 to 35 kg/m2, will be randomly assigned to one of 3 groups: 3g/d LCn-3s (N-3), a 12-week nutrition and exercise education program plus olive oil (P-LC) or the education program plus LCn-3s (EX+N-3)...
April 16, 2014: BMC Cancer
https://www.readbyqxmd.com/read/24314824/baseline-comprehensive-geriatric-assessment-is-associated-with-toxicity-and-survival-in-elderly-metastatic-breast-cancer-patients-receiving-single-agent-chemotherapy-results-from-the-omega-study-of-the-dutch-breast-cancer-trialists-group
#4
RANDOMIZED CONTROLLED TRIAL
M E Hamaker, C Seynaeve, A N M Wymenga, H van Tinteren, J W R Nortier, E Maartense, H de Graaf, F E de Jongh, J J Braun, M Los, J G Schrama, A E van Leeuwen-Stok, S M de Groot, C H Smorenburg
AIM: To evaluate the association between baseline comprehensive geriatric assessment (CGA) or the Groningen Frailty Indicator (GFI) and toxicity in elderly metastatic breast cancer (MBC) patients treated with first-line palliative chemotherapy. PATIENTS AND METHODS: MBC patients (≥65 years) were randomized between pegylated liposomal doxorubicine or capecitabine. CGA included instrumental activities of daily living (IADL), cognition using the mini-mental state examination (MMSE), mood using the geriatric depression scale (GDS), comorbidity using the Charlson index, polypharmacy and nutritional status using the body mass index...
February 2014: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/23269781/examination-of-the-association-of-diet-and-persistent-cancer-related-fatigue-a-pilot-study
#5
Suzanna M Zick, Ananda Sen, Theresa L Han-Markey, Richard E Harris
PURPOSE/OBJECTIVES: To examine associations between diet and persistent cancer-related fatigue (PCRF) in cancer survivors. DESIGN: A cross-sectional pilot study. SETTING: A university cancer center in Michigan. SAMPLE: 40 adult cancer survivors who were recruited from July 2007 to August 2008 and had completed all cancer treatments at least 12 weeks prior to recording their dietary intakes and fatigue severity. METHODS: Participants' fatigue was assessed with the Brief Fatigue Inventory (BFI)...
January 2013: Oncology Nursing Forum
https://www.readbyqxmd.com/read/22412148/fatigue-inflammation-and-%C3%AF-3-and-%C3%AF-6-fatty-acid-intake-among-breast-cancer-survivors
#6
MULTICENTER STUDY
Catherine M Alfano, Ikuyo Imayama, Marian L Neuhouser, Janice K Kiecolt-Glaser, Ashley Wilder Smith, Kathleen Meeske, Anne McTiernan, Leslie Bernstein, Kathy B Baumgartner, Cornelia M Ulrich, Rachel Ballard-Barbash
PURPOSE: Evidence suggests that inflammation may drive fatigue in cancer survivors. Research in healthy populations has shown reduced inflammation with higher dietary intake of ω-3 polyunsaturated fatty acids (PUFAs), which could potentially reduce fatigue. This study investigated fatigue, inflammation, and intake of ω-3 and ω-6 PUFAs among breast cancer survivors. METHODS: Six hundred thirty-three survivors (mean age, 56 years; stage I to IIIA) participating in the Health, Eating, Activity, and Lifestyle Study completed a food frequency/dietary supplement questionnaire and provided a blood sample assayed for C-reactive protein (CRP) and serum amyloid A (30 months after diagnosis) and completed the Piper Fatigue Scale and Short Form-36 (SF-36) vitality scale (39 months after diagnosis)...
April 20, 2012: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/17500503/cancer-cachexia-and-targeting-chronic-inflammation-a-unified-approach-to-cancer-treatment-and-palliative-supportive-care
#7
REVIEW
Neil MacDonald
Chronic inflammation often acts as a tumor promoter, resulting in aggressive cancerous growth and spread. Many of the same inflammatory factors that promote tumor growth also are responsible for cancer cachexia/anorexia, pain, debilitation, and shortened survival. A compelling case may be made for mounting an attack on inflammation with other anticancer measures at initial diagnosis, with the consequent probability of improving both patient quality of life and survival. High serum levels of the inflammatory marker C-reactive protein or fibrinogen and an elevated white blood cell count correlate with poor prognosis and may be used as a prognostic index to establish the need for nutritional/metabolic intervention...
April 2007: Journal of Supportive Oncology
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