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Birgit Fritz, Anne Jenner, Siegfried Wahl, Christian Lappe, Achim Zehender, Christian Horn, Frithjof Blessing, Matthias Kohl, Focke Ziemssen, Markus Egert
Surfaces with regular contact with the human body are typically contaminated with microorganisms and might be considered as fomites. Despite spectacles being widespread across populations, little is known about their microbial contamination. Therefore, we swab-sampled 11 worn spectacles within a university setting as well as 10 worn spectacles in a nursing home setting. The microbial load was determined by aerobic cultivation. All spectacles were found to be contaminated with bacteria, with nose pads and ear clips having the highest density, i...
2018: PloS One
Ademola Adetokunbo Oyagbemi, Temidayo Olutayo Omobowale, Olufunke Eunice Ola-Davies, Ebunoluwa Racheal Asenuga, Temitayo Olabisi Ajibade, Olumuyiwa Abiola Adejumobi, Jeremiah Moyinoluwa Afolabi, Blessing Seun Ogunpolu, Olufunke Olubunmi Falayi, Adebowale Bernard Saba, Adeolu Alex Adedapo, Momoh Audu Yakubu
The use of sodium fluoride (NaF) as a major ingredient for tooth paste, mouth wash, and mouth rinse has become inevitable in our day-to-day life. However, flavonoids such as Luteolin might be of great value in the prevention of toxicity associated with accidental or inevitable ingestion of NaF. In the study, 40 male Wistar albino rats were randomly divided into four groups with 10 rats in a group. Group A was the control group and received normal saline, Group B was exposed to NaF at 300 ppm (300 mg/L) in drinking water daily for a week, Groups C and D were exposed to 300 ppm (300 mg/L) of NaF and coadministered with Luteolin orally daily at a dosage of 100 mg/kg and 200 mg/kg for the same time point...
November 26, 2018: BioFactors
Nkosinathi Blessing Ngcobo, Pranitha Maharaj, Divane Nzima
Men's involvement in sexual and reproductive health is under-researched in South Africa despite evidence to suggest that men are key decision-makers in various household matters. Against this background, this study aimed to explore men's perspectives on contraceptive use in a South African township with a focus on motivations for contraception use and the challenges men face in using contraceptives. In-depth interviews were conducted with a sample of 20 men. Findings suggest that awareness of contraception among men is high and attitudes towards contraceptives are generally favourable...
November 22, 2018: Culture, Health & Sexuality
Hanna Y Berhane, Eva-Charlotte Ekström, Magnus Jirström, Yemane Berhane, Christopher Turner, Beatrix W Alsanius, Jill Trenholm
Many studies have drawn attention to the vital role mothers have in safeguarding the health and nutritional wellbeing of their children. However, little is known about mothers' experiences and the challenges they face in fulfilling this role in rapidly urbanizing cities in Africa. This study aims to explore child care and feeding practices of mothers with children under five years of age in Addis Ababa, Ethiopia. This qualitative study was conducted using a semi-structured interview guide. A total of thirty-six interviews were conducted with purposively selected participants...
2018: PloS One
Hanadi Ajam Oughli, Gengsheng Chen, J Philip Miller, Ginger Nicol, Meryl A Butters, Michael Avidan, Susan Stark, Eric J Lenze
OBJECTIVE: We examined cognitive function in nondemented, nondelirious older adults 1 year post hip fracture. DESIGN: Prospective observational study. SETTING AND PARTICIPANTS: Three hundred eighty-six hip fracture patients aged 60 years and older with no history of cognitive impairment, such as clinical dementia or persistent delirium, recruited from eight area hospitals 2-3 days after hip surgery (week 0), and 101 older adults with no recent acute medical events for control comparison...
November 2018: American Journal of Geriatric Psychiatry
William W Blessing
Daily life involves interactions with the external environment. In rats these apparently spontaneous interactions, often associated with the search for food, alternate with periods of rest in both the dark and light periods of the 24-hour day. Kleitman, in whose laboratory rapid eye movement sleep was discovered, referred to the temporal pattern as "the basic rest-activity cycle." The active periods of the basic rest-activity cycle occur approximately every 1-2 hours in an irregular stochastic pattern that has been described (perhaps unhelpfully) as ultradian rhythmicity...
2018: Handbook of Clinical Neurology
Matthew S Painschab, Edwards Kasonkanji, Takondwa Zuze, Bongani Kaimila, Tamiwe Tomoka, Richard Nyasosela, Ruth Nyirenda, Bal M Dhungel, Maurice Mulenga, Maria Chikasema, Blessings Tewete, Asekanadziwa Mtangwanika, Sarah Chiyoyola, Wilberforce Mhango, Fred Chimzimu, Coxcilly Kampani, Robert Krysiak, Thomas C Shea, Nathan D Montgomery, Yuri Fedoriw, Satish Gopal
Outcomes for diffuse large B-cell lymphoma (DLBCL) in sub-Saharan Africa (SSA) are poorly described. We report mature data from one of the first prospective SSA cohorts. Patients aged ≥18 years with DLBCL were enrolled in Malawi 2013-2017. Participants were treated with CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy and concurrent antiretroviral therapy (ART) if positive for human immunodeficiency virus (HIV+). Eighty-six participants (mean age 47 years, standard deviation 13) were enrolled: 54 (63%) were male and 51 (59%) were HIV+, of whom 34 (67%) were on ART at DLBCL diagnosis...
November 18, 2018: British Journal of Haematology
Werner Vach, Franziska Saxer, Anders Holsgaard-Larsen, Soeren Overgaard, Erik Farin-Glattacker, Nicolas Bless, Heiner C Bucher, Marcel Jakob
BACKGROUND Surgical registries are becoming increasingly popular. In addition, Swiss legislation requires data on therapeutic outcome quality. The Swiss Association of Surgeons (Schweizerische Gesellschaft Chirurgie, SGC-SCC) has already agreed on a first minimum data set. However, in the long run the scope and content of the registry should be evidence-based and not only accepted by professional stakeholders. The MIDAS study aims at providing such evidence for the example population of patients undergoing emergency or elective hip surgery...
November 5, 2018: Swiss Medical Weekly
Tamiwe Tomoka, Matthew S Painschab, Nathan D Montgomery, Ryan Seguin, Maurice Mulenga, Bongani Kaimila, Edwards Kasonkanji, Takondwa Zuze, Richard Nyasosela, Ruth Nyirenda, Maria Chikasema, Blessings Tewete, Asekanadziwa Mtangwanika, Sarah Chiyoyola, Fred Chimzimu, Coxcilly Kampani, Yuri Fedoriw, Satish Gopal
No abstract text is available yet for this article.
November 15, 2018: Haematologica
H A Girgis, R W Kloet, H J Lamb, J M Montero-Cabezas
No abstract text is available yet for this article.
November 13, 2018: European Heart Journal
Amy Loughman, Nick Haslam
Genetic and other biological explanations appear to have mixed blessings for the stigma of mental disorder. Meta-analytic evidence shows that these "biogenetic" explanations reduce the blame attached to sufferers, but they also increase aversion, perceptions of dangerousness, and pessimism about recovery. These relationships may arise because biogenetic explanations recruit essentialist intuitions, which have known associations with prejudice and the endorsement of stereotypes. However, the adverse implications of biogenetic explanations as a set may not hold true for the subset of those explanations that invoke neurobiological causes...
November 14, 2018: Cognitive Research: Principles and Implications
Muhammad Athar Khaliq, Blessing James, Yan Hui Chen, Hafiz Sohaib Ahmed Saqib, Hong Hong Li, Pathmamali Jayasuriya, Wang Guo
An analysis of the Cd and mineral nutrients accumulation of upland rice was performed in an experimental field with hard-ridged plots containing three soils with exogenous Cd addition at rates of 0, 0.25, 0.5, 1, 2, 4, 8, 16 mg kg-1 five years prior to commence this experiment. Aims of this investigation were to study uptake, translocation, and accumulation of Cd by an upland rice (Huyou2) and effects of Cd addition on the accumulation of Fe, Zn, Ni, Ca, and Mg. The results demonstrate the mean Cd content in the plant parts, from highest to lowest, were as follows: root, stem, leaf, and brown rice...
January 2019: Chemosphere
Mariana Brizuela, Steven J Swoap, James Ang, William W Blessing, Youichirou Ootsuka
The lateral habenula (LHb), a nucleus involved in the response to salient, especially adverse, environmental events, is implicated in brown adipose tissue (BAT) thermogenesis caused by these events. LHb-elicited thermogenesis involves a neural pathway to the lower brainstem sympathetic control center in the medullary raphé. There are no direct connections from the LHb to the medullary raphé. LHb-mediated behavioral responses involve inhibitory control over the dopamine neurons in the ventral tegmental area (VTA), mediated via an excitatory drive from the LHb to GABAergic neurons in the tail of the VTA...
November 8, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Celia M J Matyanga, Blessing Dzingirai
Emergency contraceptives play a major role in preventing unwanted pregnancy. The use of emergency contraceptives is characterized by myths and lack of knowledge by both health professionals and users. The main objective of this paper is to summarize the clinical pharmacology of hormonal methods of emergency contraception. A literature review was done to describe in detail the mechanism of action, efficacy, pharmacokinetics, safety profile, and drug interactions of hormonal emergency contraceptive pills. This information is useful to healthcare professionals and users to fully understand how hormonal emergency contraceptive methods work...
2018: International Journal of Reproductive Medicine
Francis Chizoruo Ibe, Alexander Iheanyichukwu Opara, Bridget Onyekachi Ibe, Blessing Chinonso Adindu, Bright Chigozie Ichu
Assessment of trace metal concentrations in street-deposited sediments around some selected electronic repair workshops in Owerri, Imo State, Nigeria, was carried out. The objective of the study was to determine the concentrations of trace metals, namely nickel (Ni), chromium (Cr), lead (Pb), copper (Cu), cadmium (Cd), and zinc (Zn), in surface dusts from streets within some electronic repair workshops in Owerri, Imo State, Nigeria. Dust samples were collected from seven locations within the month of January 2014 during the dry season when the onset of dust was high in the area...
November 3, 2018: Environmental Monitoring and Assessment
Joseph K Kamara, Blessing J Akombi, Kingsley Agho, Andre M N Renzaho
The available literature suggests that natural disasters, especially droughts and floods, were occurring in southern Africa in the early 1900s. However, their frequency and intensity increased during the 1980s. The aim of this systematic review was to assess the relationship between resilience to droughts and people's well-being in southern Africa. A combination of keywords was used to search the following 13 electronic bibliographic databases: Africa Journal Online (AJOL), MEDLINE, Academic Search Complete, Environment Complete, Humanities International Complete, Psychology and Behavioral Sciences Collection, PsycINFO, Embase, Scopus, Web of Science, Applied Social Science Index and Abstracts, ProQuest Central, and CINAHL...
October 26, 2018: International Journal of Environmental Research and Public Health
Peter S Harper
No abstract text is available yet for this article.
October 27, 2018: Human Genetics
Alexander N Gorban, Valeri A Makarov, Ivan Y Tyukin
Complexity is an indisputable, well-known, and broadly accepted feature of the brain. Despite the apparently obvious and widely-spread consensus on the brain complexity, sprouts of the single neuron revolution emerged in neuroscience in the 1970s. They brought many unexpected discoveries, including grandmother or concept cells and sparse coding of information in the brain. In machine learning for a long time, the famous curse of dimensionality seemed to be an unsolvable problem. Nevertheless, the idea of the blessing of dimensionality becomes gradually more and more popular...
October 2, 2018: Physics of Life Reviews
S V Berwin Singh, Angela Guma Adam, Nirmalya Tripathy, Dongwon Lee, Gilson Khang
Reactive Oxygen Species (ROS) play a vital role in the biological system. Exaggerated, ROS have devastating effects on the human body leading to the pathophysiological condition including the transformation of a normal cell into a cancer phenotype. Nature has blessed us with various biomolecules that we use along with our dietary supplements. Using such therapeutic small molecules covalently incorporated into biodegradable polyoxalate polymer backbone with a responsive group forms an efficient drug delivery vehicle...
2018: Advances in Experimental Medicine and Biology
Zev M Nakamura, Allison M Deal, Kirsten A Nyrop, Seul Ki Choi, William A Wood, Hyman B Muss
OBJECTIVE: To describe associations of functional, psychosocial, medical, and socio-demographic factors with performance on a cognitive screening test in chemotherapy naïve patients with breast cancer. METHODS: Women with breast cancer were recruited between 2009 and 2018. The Blessed Orientation Memory Concentration Test (BOMC) was administered prior to chemotherapy. Associations between baseline BOMC and functional (Karnofsky Self-Reported Performance Rating Scale (KPS), Time Up and Go Test (TUG), Medical Outcomes Study (MOS) Physical Function, Instrumental Activities of Daily Living (IADL)), psychosocial (Mental Health Inventory-13, MOS Social Activity Limitation and Social Support Survey), medical, and socio-demographic variables were assessed using linear regression analysis...
October 23, 2018: Psycho-oncology
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