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https://www.readbyqxmd.com/read/30113512/predictors-of-outcome-in-selective-laser-trabeculoplasty-a-long-term-observation-study-in-primary-angle-closure-glaucoma-after-laser-peripheral-iridotomy-compared-to-primary-open-angle-glaucoma
#1
Natalia Ivanovna Kurysheva, Lyudmila Vyacheslavovna Lepeshkina, Ekaterina Olegovna Shatalova
PURPOSE: To evaluate the efficacy of selective laser trabeculoplasty (SLT) for patients with primary angle closure glaucoma (PACG) following a YAG laser peripheral iridotomy (PI) in comparison with primary open angle glaucoma (POAG) and to assess the predictors of outcome of SLT. PATIENTS AND METHODS: In retrospective study 68 patients with PACG after PI (68 eyes) and 74 POAG patients (74 eyes) were observed for 6 years. The effectiveness of SLT (20% reduction of intraocular pressure) was assessed using Kaplan-Meier survival analysis...
August 14, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/30111716/atmospheric-pressure-plasma-mediated-synthesis-of-platinum-nanoparticles-stabilized-by-poly-vinylpyrrolidone-with-application-in-heat-management-systems-for-internal-combustion-chambers
#2
Anna Dzimitrowicz, Piotr Cyganowski, Pawel Pohl, Dorota Jermakowicz-Bartkowiak, Dominik Terefinko, Piotr Jamroz
Poly(vinylpyrrolidone)-stabilized Pt nanoparticles (PVP-PtNPs) were produced in a continuous-flow reaction-discharge system by application of direct current atmospheric pressure glow discharge (dc-APGD) operated between the surface of a flowing liquid anode (FLA) and a pin-type tungsten cathode. Synthesized PVP-PtNPs exhibited absorption across the entire UV/Vis region. The morphology and elemental composition of PVP-PtNPs were determined with transmission electron microscopy (TEM) and energy dispersive X-ray scattering (EDX), respectively...
August 15, 2018: Nanomaterials
https://www.readbyqxmd.com/read/30111429/-hypobaric-hypoxia-induces-autophagy-of-umbilical-cord-mesenchymal-stem-cells
#3
Jiao-Jiao Yin, Bing Li, Qiang Zhao, Shu-Ting Zhang, Yao-Zhu Pan, Hai Bai
OBJECTIVE: To investigate the autophagy activity changes of umbilical cord mesenchymal cells (MSC) under hypobaric hypoxia and the effect of hypobaric hypoxia on cell viability. METHODS: Umbilical cord mesenchymal cells were cultured in the chamber of hypobaric hypoxia with an air pressure of 41.1 kPa and an oxygen density of 1%. At 0, 4, 8, 16, 24 and 48 hours, the cells were harvested for Western blot and real-time PCR to observe the expression level of the autophagy marker protein LC3B...
August 2018: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/30110731/orchestrating-cells-on-a-chip-employing-surface-acoustic-waves-towards-the-formation-of-neural-networks
#4
Manuel S Brugger, Sarah Grundeen, Adele Doyle, Luke Theogarajan, Achim Wixforth, Christoph Westerhausen
For the investigation of cell-cell interaction in general and for neural communication and future applications of neural networks, a controllable and well-defined network structure is crucial. We here propose the implementation of an acoustically driven system for tunable and deliberate stimulation and manipulation of cell growth on a chip. This piezoelectric chip allows us to generate a checkerboard-like standing surface acoustic wave pattern coupled to a fluid layer in a microfluidic chamber on top. Such a dynamically induced patterning lattice is shown to allow for the active positioning of the neurons and subsequent guided neurite outgrowth, thus finally overcoming the limitations of static approaches...
July 2018: Physical Review. E
https://www.readbyqxmd.com/read/30109969/antimicrobial-treatment-of-escherichia-coli-and-staphylococcus-aureus-in-herbal-tea-using-low-temperature-plasma
#5
Artit Chingsungnoen, Sujira Maneerat, Poramate Chunpeng, Phitsanu Poolcharuansin, Rachanee Nam-Matra
A low-pressure capacitively coupled discharge was used to study antimicrobial treatment in herbal tea. Ambient air with a relative humidity of 40% was used as a precursor gas and fed into the chamber via a perforated power electrode. An electrical discharge plasma was produced at a radio frequency of 10 kHz and power of 80 W. The operating pressure during treatment was kept constant at 260 Pa. The target microorganisms, Escherichia coli and Staphylococcus aureus, isolated from the herbal tea were inoculated on nutrient agar petri dishes and exposed to the plasma for 0...
August 15, 2018: Journal of Food Protection
https://www.readbyqxmd.com/read/30108659/vasorelaxant-and-hypotensive-effects-of-cheonwangbosimdan-in-sd-and-shr-rats
#6
Bumjung Kim, Cheolmin Jo, Ho-Young Choi, Kyungjin Lee
Historically, traditional herbal medicines (THMs) have been the conventional treatment strategy in the Korean medical system for treating many diseases. However, THMs have rarely been used to treat hypertension, and moreover few studies have investigated the interaction of blood pressure with the coadministration of synthetic antihypertensives. We aimed to evaluate the vasorelaxant and hypotensive effects of the traditional herbal prescription Cheonwangbosimdan (CWBSD; "Tianwangbuxindan" in Chinese) and the combination of CWBSD with amlodipine...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/30107418/patterns-of-fish-reproduction-at-the-interface-between-air-and-water
#7
Atsushi Ishimatsu, Hieu Van Mai, Karen L M Martin
Although fishes by nature are aquatic, many species reproduce in such a way that their embryos are exposed to air either occasionally or constantly during incubation. We examine the ecological context and review specific examples of reproduction by fishes at the air-water interface, including fishes that do and do not breathe air. Four modes of reproduction at the air-water interface are described across 18 teleost Orders, from fresh water, estuaries and sea water. Mode 1, the most common type of reproduction by fishes at the air-water interface, includes 21 Families of mostly marine teleosts that spawn in water onto a substrate surface, on vegetation, or into hollow objects such as shells that will later be continuously or occasionally exposed to air...
August 13, 2018: Integrative and Comparative Biology
https://www.readbyqxmd.com/read/30105483/the-impact-of-nd-yag-laser-posterior-capsulotomy-by-the-use-of-the-circular-pattern-with-vitreous-strand-cut-technique-on-anterior-chamber-parameters
#8
Nermien Salah El-Dien Mohammed El-Haddad
AIM: The purpose of this study is to identify the effect of Nd: YAG laser posterior capsulotomy using an anterior chamber morphology. METHODS: This study included 42 eyes of 33 pseudophakic patients with visually significant PCO after uncomplicated cataract surgery. Exclusion criteria were complications related to cataract surgery, corneal pathology, pseudoexfoliation, glaucoma, uveitis, previous ocular surgery or trauma, and posterior segment pathology. All patients underwent routine ophthalmic examinations...
August 13, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/30101520/a-novel-patient-oriented-numerical-procedure-for-glaucoma-drainage-devices
#9
Alessandro Mauro, Nicola Massarotti, Salahudeen Mohamed, Ignacio Rodríguez Uña, Mario R Romano, Vito Romano
The present work analyses the performance of four glaucoma drainage devices, by means of a novel patient-oriented numerical procedure. The procedure is based on the three-dimensional geometry reconstruction from the stacks of tomographic images of a human eye, at different angles, on meshing and on thermo-fluid dynamics modelling activities, carried out on the reconstructed computational domain. The current three-dimensional eye model considers Anterior Chamber (AC), Trabecular Meshwork (TM), Schlemm's Canal (SC) and Collector Channels (CC), making use of Generalized Porous Medium (GPM) approach for modelling ocular porous tissue and cavities...
August 12, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/30098187/ultrastructural-morphology-of-the-optic-nerve-head-in-aged-and-glaucomatous-mice
#10
Ying Zhu, Anthony C Pappas, Rui Wang, Philip Seifert, Daniel Sun, Tatjana C Jakobs
Purpose: To study age- and intraocular pressure-induced changes in the glial lamina of the murine optic nerve on the ultrastructural level. Methods: Naïve C57bl/6 mice at various ages spanning the time between early adulthood (3 months) and senescence (30 months) were used in this study. In addition, the intraocular pressure (IOP) was increased in a group of young mice by injection of microbeads into the anterior chamber. The unmyelinated segments of the optic nerve containing the glial lamina were prepared for transmission electron microscopy and imaged at high resolution...
August 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/30098125/quantitative-assessment-of-changes-in-anterior-segment-morphology-after-argon-laser-peripheral-iridoplasty-findings-from-the-earl-study-group
#11
K-A Dawn Lim, Hwei Wuen Chan, Ce Zheng, Maria C Aquino, Robert Ritch, Paul Tk Chew
IMPORTANCE: Argon laser peripheral iridoplasty (ALPI) could be effective in widening residual angle closure following laser peripheral iridotomy (LPI). BACKGROUND: We investigated changes in angle parameters following ALPI and its safety profile in this study. DESIGN: Retrospective, observational case series. PARTICIPANTS: The records from a single center, of 36 patients (60 eyes) who underwent ALPI, for residual angle closure following LPI, were reviewed...
August 11, 2018: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/30097169/changes-in-left-atrial-function-after-transcutaneous-mitral-valve-repair
#12
Eleonora Avenatti, Stephen H Little, Colin M Barker, Sherif F Nagueh
Left atrial (LA) reverse remodeling occurs after transcatheter mitral valve repair, but additional data are needed about changes in LA function. Changes in LA stiffness in patients undergoing MitraClip implantation were evaluated. Baseline, procedural, and 30-day follow-up clinical and imaging data of patients undergoing MitraClip were reviewed. LA operating chamber stiffness was calculated as the ratio of systolic change in LA pressure to LA systolic strain and to stroke volume. Matched preprocedure and postprocedure LA strain analyses were performed in 35 patients, 21 with primary and 14 with functional mitral regurgitation (MR)...
July 5, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/30096941/humidity-measurement-in-carbon-dioxide-with-capacitive-humidity-sensors-at-low-temperature-and-pressure
#13
Andreas Lorek, Jacek Majewski
In experimental chambers for simulating the atmospheric near-surface conditions of Mars, or in situ measurements on Mars, the measurement of the humidity in carbon dioxide gas at low temperature and under low pressure is needed. For this purpose, polymer-based capacitive humidity sensors are used; however, these sensors are designed for measuring the humidity in the air on the Earth. The manufacturers provide only the generic calibration equation for standard environmental conditions in air, and temperature corrections of humidity signal...
August 9, 2018: Sensors
https://www.readbyqxmd.com/read/30096794/redox-biology-of-right-sided-heart-failure
#14
REVIEW
Nataliia V Shults, Oleksiy Melnyk, Dante I Suzuki, Yuichiro J Suzuki
Right-sided heart failure is the major cause of death among patients who suffer from various forms of pulmonary hypertension and congenital heart disease. The right ventricle (RV) and left ventricle (LV) originate from different progenitor cells and function against very different blood pressures. However, differences between the RV and LV formed after birth have not been well defined. Work from our laboratory and others has accumulated evidence that redox signaling, oxidative stress and antioxidant regulation are important components that define the RV/LV differences...
August 8, 2018: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/30096594/the-risk-of-glaucoma-and-serotonergic-antidepressants-a-systematic-review-and-meta-analysis
#15
REVIEW
Hung-Yu Wang, Ping-Tao Tseng, Brendon Stubbs, Andre F Carvalho, Dian-Jeng Li, Tien-Yu Chen, Pao-Yen Lin, Yu-Te Hsueh, Yu-Zhen Chen, Yen-Wen Chen, Che-Sheng Chu
BACKGROUND: The aim of current study was to conduct a systematic review and meta-analysis to explore the relationship between antidepressant use and glaucoma. METHODS: Eight major electronic databases were searched from inception until March 19th, 2018 to obtain relevant studies that evaluated associations of antidepressants [including selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs)] treatment and the risk of primary open-angle glaucoma (POAG) or primary angle-closure glaucoma (PACG) as well as intraocular pressure (IOP), and related anterior chamber parameters compared to participants not exposed to antidepressant treatment...
July 31, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/30094117/syncopal-episodes-of-arrhythmogenic-right-ventricular-cardiomyopathy-in-a-patient-with-pre-existing-seizure-disorder
#16
James R Kimber, Syed Rafay Ali Sabzwari, Hiwot Ayele
Arrhythmogenic right ventricular cardiomyopathy (ARVC), is a heritable condition that is an important, and under-recognized cause of sudden cardiac death. Microscopically, it is represented by fibrofatty replacement of myocardium involving the right ventricular inflow area, apex, and infundibulum. Common clinical manifestations of ARVC include palpitations, syncope, chest pain, dyspnea, and sudden cardiac death. This is a case of a 25-year-old male with a history of thalassemia, and tonic-clonic seizure status post head trauma with cystic encephalomalacia in left parietal lobe who described recurrent syncope...
June 7, 2018: Curēus
https://www.readbyqxmd.com/read/30092400/the-ace-2-activator-diminazene-aceturate-dize-improves-left-ventricular-diastolic-dysfunction-following-myocardial-infarction-in-rats
#17
Carmen Castardeli, Carmem Luíza Sartório, Enildo Broetto Pimentel, Ludmila Forechi, José Geraldo Mill
Diminazene aceturate (DIZE) has been reported to enhance the catalytic efficiency of ACE-2 and presumably increases angiotensin 1-7 generation, interfering with cardiac remodeling after myocardial infarction (MI). Our aim was to investigate the chronic effects of DIZE on cardiac dysfunction post-MI. Male Wistar rats underwent myocardial infarction (MI) or SHAM surgery (SO) and were divided into groups treated with DIZE 15 mg/kg/day, s.c. or vehicle (Control). After 4 weeks, the hemodynamic variables were recorded by cardiac catheterism...
August 6, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/30090177/mini-vitrectomy-a-simple-solution-to-a-serious-condition
#18
Mohammad Pakravan, Hamed Esfandiari, Nassim Amouhashemi, Amir Veisi, Pooya Torkian, Shahin Yazdani
Purpose: To evaluate the safety and efficacy of clear corneal approach irido-zonulo-hyaloido-vitrectomy, which we named "mini-vitrectomy," in the management of pseudophakic aqueous misdirection. Methods: In this retrospective, non-comparative interventional case series, 24 eyes with diagnosis of pseudophakic aqueous misdirection were enrolled. Medical therapy with cycloplegics and laser therapy, including posterior capsulotomy and hyaloidotomy, was not effective in the management of the condition...
July 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/30088168/a-combined-approach-for-the-analysis-of-ocular-fluid-dynamics-in-the-presence-of-saccadic-movements
#19
Marco Ferroni, Matteo Giuseppe Cereda, Federica Boschetti
One of the main ocular diseases is age-related macular degeneration, actually treated with antibodies injections into the eye. This problem has been faced by computational approaches, taking into account either the influence of the tissues surrounding the vitreous, or the saccades. The aim of this work is to propose a combined fluid dynamic model of the vitreous chamber that analyses the impact of the saccades on the fluid dynamic mechanisms. The ocular vitreous humor was modeled considering liquefaction occurring in presence of age-related macular degeneration...
August 7, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/30081013/comparison-of-anterior-segment-optical-coherence-tomography-parameters-among-vietnamese-chinese-and-caucasians
#20
Sunee Chansangpetch, Brendan Tran, Claudio I Perez, Christine Siguan-Bell, Kevin Lau, Anh-Hien Nguyen, Andy Thai, Mingguang He, Dandan Wang, Ngoc Nguyen, Shan C Lin
PURPOSE: To evaluate the difference in anterior segment optical coherence tomography (AS-OCT) parameters among ethnic Vietnamese, Chinese, and Caucasians DESIGN: Cross-sectional study METHODS: We prospectively recruited phakic non-glaucomatous participants (based on intraocular pressure <21 mmHg, normal optic nerve head and retinal nerve fiber, and cup-to-disc ratio <0.6) of three ethnic groups- Vietnamese, Chinese, and Caucasians. AS-OCT parameters including angle (angle opening distance, trabecular-iris space area, and angle recess area), iris (iris thickness, iris area, and iris curvature (Icurv)), and anterior chamber parameters (anterior chamber depth, width (ACW), area, and lens vault (LV)) were obtained...
August 3, 2018: American Journal of Ophthalmology
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