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Ryo Morishima, Kei Nakashima, Shinya Suzuki, Nobuo Yamami, Masahiro Aoshima
Immersion pulmonary oedema (IPE) is particularly associated with an excessive reaction to exercise and/or cold stress. IPE usually resolves without recompression therapy within a day or two. Herein we report a diver diagnosed with IPE, in whom symptoms persisted for five days. A 58-year-old man presented with sudden onset of dyspnoea, cough and haemoptysis after surfacing. He was an experienced diving instructor with a history of moderate mitral valve regurgitation. While IPE was diagnosed and oxygen administered, respiratory symptoms deteriorated, and serum C-reactive protein elevated...
December 24, 2018: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
Hongjie Yi, Shichong Yu, Yanan Zhang, Runping Li, Dazhi Zhang, Dazhi Zhang, Weigang Xu
BACKGROUND: Recent studies indicated that ketone ester R,S-1,3-butanediol acetoacetate diester (BD-AcAc2 ) may be effective in preventing central nervous system oxygen toxicity (CNS-OT) and concomitant acute lung injury, a serious medical problem to be faced when breathing hyperbaric oxygen (HBO). This study aimed to further investigate the protective effects of BD-AcAc2 against CNS-OT and concomitant acute lung injury (ALI) in mice. METHODS: Mice were treated with BD-AcAc2 in peanut oil vehicle (2...
December 24, 2018: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
Hooi Geok See, Yan Ru Tan, Kwan Leong Au-Yeung, Michael H Bennett
BACKGROUND: Nutritional assessment and support is essential for wound management. The hyperbaric oxygen clinic is a unique outpatient service where chronically unwell patients present daily for hyperbaric oxygen treatment (HBOT) over several weeks, allowing time for effective nutritional intervention. This is the first study to examine the prevalence of those at risk of malnutrition in a cohort of hyperbaric medical patients. METHODS: A prospective study was undertaken over six months...
December 24, 2018: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
Marion Hubbard, F Michael Davis, Kate Malcolm, Scott J Mitchell
INTRODUCTION: Health and safety within the recreational diving industry are poorly described. We aimed to obtain the true prevalence of decompression illness (DCI) and other diving and non-diving injuries, including occupational injuries, in a large recreational diving charter operation. METHODS: A New Zealand recreational diving operator keeps detailed records of diving activity and event/incident reports. We extracted passenger and crew numbers, dive numbers and incident statistics from all boat trips and associated work-related injuries between 01 January 2008 and 31 December 2014...
December 24, 2018: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
Oana A Tatucu-Babet, Emma J Ridley
Outpatients who receive hyperbaric oxygen treatment (HBOT) may represent a group at significant risk of malnutrition owing to the underlying conditions that are often treated with HBOT (e.g., non-healing diabetic wounds and radiation-induced skin injury). In this issue, See and colleagues provide new, preliminary evidence of the prevalence of malnutrition in a small group of HBOT outpatients treated in an Australian hospital, reporting that approximately one-third of patients receiving HBOT were at risk of malnutrition...
December 24, 2018: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
Hsing-Hsien Wu, Ko-Chi Niu, Cheng-Hsien Lin, Hung-Jung Lin, Ching-Ping Chang, Chia-Ti Wang
High-mountain sickness is characterized by brain and pulmonary edema and cognitive deficits. The definition can be fulfilled by a rat model of high-altitude exposure (HAE) used in the present study. This study aimed to investigate the protective effect of hyperbaric oxygen therapy (HBO2 T) and to determine the underlying mechanisms. Rats were subjected to an HAE (9.7% O2 at 0.47 absolute atmosphere of 6,000 m for 3 days). Immediately after termination of HAE, rats were treated with HBO2 T (100% O2 at 2.0 absolute atmosphere for 1 hour per day for 5 consecutive days) or non-HBO2 T (21% O2 at 1...
2018: BioMed Research International
Xiaomin Chen, Yue Wang, Fangfang Han, Min Ke
Purpose: Glaucoma is the leading cause of irreversible blindness throughout the world. The pathogenesis of glaucoma is complex, and neuroprotection is a crucial aspect of therapy. High concentrations of extracellular glutamate are toxic to the optic nerve. The glutamate-aspartate transporter (GLAST) in retinal Müller cells is involved in the development of glaucoma. Anthocyanin has been reported to protect retinal neurons. We hypothesize that cyanin chloride, a type of anthocyanin, can inhibit hyperbaric pressure-induced GLAST decreases in cultured rat retinal Müller cells and may serve as a potential neuroprotective agent in glaucoma treatment...
2018: Journal of Ophthalmology
Raafat M Reyad, Sameh M Hakim, Dina N Abbas, Hossam Z Ghobrial, Ekramey Mansour
BACKGROUND: The prevalence of pain in advanced pelvic cancer may reach up to 95%. Control of such pain is often difficult owing to a variety of neuroanatomical and functional peculiarities. Different modalities have been utilized to treat this pain including saddle chemical rhizolysis with the potential for jeopardizing the neural control of the sphincters. OBJECTIVE: The aim of this pilot study is to determine the feasibility of using selective thermal radiofrequency as an alternative to saddle chemical rhizolysis in patients with refractory perineal pain associated with pelvic malignancies...
November 2018: Pain Physician
L H Hitchman, J P Totty, A Raza, P Cai, G E Smith, D Carradice, T Wallace, A E Harwood, I C Chetter
OBJECTIVES: To assess the current available evidence examining the efficacy of extracorporeal shockwave therapy (ESWT) on healing of diabetic foot ulcers (DFU). DATA SOURCES: PubMed, Ovid MEDLINE, Web of Science, Embase, CINAHL Plus, Cochrane Central Registry of Controlled Trials and Clinical Trials Registry electronic databases were searched up to November 2017 for terms related to ESWT in DFU. REVIEW METHODS: Articles were identified and data extracted by two independent reviewers onto Review Manager 5...
November 26, 2018: Annals of Vascular Surgery
Sarah Mancini, Angela M Crotty, Jerald Cook
BACKGROUND: Decompression sickness is a condition that results from an abrupt change from a higher to a lower pressure. It is described most commonly in divers; however, it can occur in aviation incidents, which this case report will discuss. CASE REPORT: Following an acute cabin depressurization incident, 36 patients presented to a small outpatient clinic with multiple symptoms, including fatigue, headache, nausea, vomiting, and dizziness. These patients were evaluated, triaged, and some were able to be successfully treated with supplemental oxygen in clinic...
December 1, 2018: Aerospace Medicine and Human Performance
Shu-Chen Liao, Yan-Chiao Mao, Kun-Ju Yang, Kuo-Cheng Wang, Li-Ying Wu, Chen-Chang Yang
OBJECTIVES: Delayed neuropsychiatric sequelae (DNS) are serious complications of carbon monoxide poisoning; neuropsychiatric disorders can occur within a few days of recovery from acute poisoning. Hyperbaric oxygen therapy (HBOT) has been the main treatment of carbon monoxide (CO) poisoning and was recommended as the treatment choice for CO poisoning by the American Undersea and Hyperbaric Medical Society and the Tenth European Consensus Conference on Hyperbaric Medicine of the European Underwater and Baromedical Society...
November 22, 2018: Journal of the Neurological Sciences
Bengusu Mirasoglu, Samil Aktas
We have read the case report about a decompression sickness that was unresponsive to hyperbaric oxygen treatment in your journal. Presented case is intriguing; however, we think there are some contradictive issues in the discussion of the case. In this letter, we aim to comment on these issues that may raise further question. Bubble formation plays a very important role for decompression sickness, but proposed mechanism is incorrect as nitrogen does not change state during decompression. Use of terminology for diving-related diseases and comments on properties of helium may cause misunderstandings...
2018: Journal of Intensive Care
S B Panina, O I Gutsenko, N P Milyutina, I V Kornienko, A A Ananyan, D Yu Gvaldin, A A Plotnikov, V V Vnukov
Here, we studied the effect of the mitochondria-targeted antioxidant SkQ1 (plastoquinone cationic derivative) on the CASP3 gene expression and caspase-3 activity in rat cerebral cortex and brain mitochondria under normal conditions and in oxidative stress induced by hyperbaric oxygenation (HBO). Under physiological conditions, SkQ1 administration (50 nmol/kg, 5 days) did not affect the CASP3 gene expression and caspase-3-like activity in the cortical cells, as well as caspase-3-like activity in brain mitochondria, but caused a moderate decrease in the content of primary products of lipid peroxidation (LPO) and an increase in the reduced glutathione (GSH) level...
October 2018: Biochemistry. Biokhimii︠a︡
L Klein, R Fabian, P Šafránek, P Paterová, I Slaninka, E Havel, P Dostál, M Serbák
Necrotizing fasciitis is a dangerous bacterial infectious disease that is not commonplace in Czech society. On the other hand, neither is it so rare that the majority of surgeons should not come across it occasionally. In the early stages, pathological changes in fascia, subcutaneous tissue and even skin may run an inconspicuous course. However, this can rapidly deteriorate into shock and sepsis which may lead to multi-organ failure and an imminent life-threatening condition. The fatality rate of necrotizing fasciitis among high-risk groups (e...
2018: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
Muhammad Adnan Khan, Syed Abdul Qader Quadri, Abdulmuqueeth Syed Kazmi, Vishal Kwatra, Anirudh Ramachandran, Aaron Gustin, Mudassir Farooqui, Sajid Sattar Suriya, Atif Zafar
Skull base osteomyelitis (SBO) is a complex and fatal clinical entity that is often misdiagnosed for malignancy. SBO is commonly a direct complication of otogenic, sinogenic, odontogenic, and rhinogenic infections and can present as central, atypical, or pediatric clival SBO. This review describes the clinical profile, investigational approach, and management techniques for these variants. A comprehensive literature review was performed in PubMed, MEDLINE, Research Gate, EMBASE, Wiley Online Library, and various Neurosurgical and Neurology journals with the keywords including: SBO, central or atypical SBO, fungal osteomyelitis, malignant otitis externa, temporal bone osteomyelitis, and clival osteomyelitis...
October 2018: Asian Journal of Neurosurgery
Junichi Suzuki
NEW FINDINGS: What is the central question of this study? Intermittent hyperbaric exposure (1.3 ATA with 20.9% O2 ) has been shown to facilitate endurance capacity by facilitating oxidative and glycolytic capacities in skeletal muscle. It currently remains unclear whether this strategy enhances endurance performance in well-trained individuals. What is the main finding and its importance? Hyperbaric exposure (1.3 ATA with 20.9% O2 ) with endurance training enhanced oxidative and glycolytic capacities and protein levels of mitochondrial transcription factor A, dynamin-related protein-1, and heat shock protein 70...
November 20, 2018: Experimental Physiology
Ashley L Farris, Colin A Cook, Warren L Grayson
Polymer-based scaffolds are used extensively in the field of regenerative medicine. These biomaterials may induce therapeutic responses through modulating a wound microenvironment with or without the addition of cells. It has long been known that oxygen is a crucial component of the microenvironment that influences cellular and physiological processes such as metabolism, proliferation, differentiation, matrix deposition, phagocytic killing, and wound healing. Consequently, several studies have investigated the potential for using oxygen-eluting biomaterials to regulate the oxygen tension within a wound microenvironment and to tune the regenerative response...
November 20, 2018: Biotechnology Progress
Gonca Hanedan Uslu, Gamze Çebi, Bengü Çobanoğlu
One of the standard treatments in laryngeal cancer is radiotherapy (RT). Many short- and long-term complications can occur in the region that has received radiotherapy. Definitive treatment of the emerging complications is still debatable, and treatment is challenging for radiation oncologists and ear nose throat specialists. Recently, hyperbaric oxygen treatment (HBOT) has become a promising alternative for the treatment of these complications. The aim of this report is to discuss the effectiveness of HBOT in the treatment of late-term RT-related potential complications in a patient with laryngeal cancer...
2018: Contemporary Oncology Współczesna Onkologia
Lauren M Botta, Gregory P Botta
BACKGROUND: Hyperbaric oxygen therapy is a rare treatment modality for hemorrhagic cystitis (HC) following BK virus reactivation in the immunosuppressed population. Clinicians need to be aware of the etiology, preventive measures, complications, and various management techniques in HC while treating patients undergoing bone marrow transplantation. OBJECTIVES: This study details the pathologic progression of HC in a patient with acute lymphoblastic leukemia harboring BK virus after cytotoxic induction chemotherapy and haploidentical marrow transplantation...
December 1, 2018: Clinical Journal of Oncology Nursing
Itay Wiser, Averbuch Sagie Roni, Ella Ziv, Mony Friedman, Shay Efraty, Lior Heller, Marina Landau, Tali Friedman
Background: Phenol chemical peeling (PCP) treatment is associated with prolonged recovery and sustained adverse events. Hyperbaric oxygen therapy (HBOT) is known to accelerate wound healing. The purpose of the current study was to evaluate the effect of HBOT on PCP recovery period and adverse events. Methods: This is a pilot randomized controlled clinical study. Women following PCP underwent 5 consecutive daily HBOT sessions, compared with PCP alone. Pain, pruritus, erythema, crusting, scaling, and edema were daily evaluated up to 28 days following PCP...
November 2018: Plastic Surgery
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