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Caner Turan, Eylem Ulas Saz
OBJECTIVE: Children are presented with an unknown intoxication at emergency department (ED) after carbon monoxide (CO) poisoning. Although CO poisoning is well defined in the adult literature, little information exists regarding CO poisoning in childhood, especially in infants. The only diagnostic test for CO poisoning is elevation of the carboxyhemoglobin level in the blood. CASE: We report the second youngest neonate in literature who was severely poisoned by CO and treated with hyperbaric oxygen at the ED...
October 17, 2018: Pediatric Emergency Care
Liao Juan, Li Peng, Wu Mengjun, Mu Yandong
PURPOSE: The impact of hyperbaric oxygen (HBO) on the healing of bone tissues around implants was studied using an animal model. METHODS: A total of 32 beagle dogs were selected and randomly divided into the HBO group and the blank group. The dogs in the HBO group were subjected to 90 minutes of HBO therapy. X-ray, cone-beam computerized tomography imaging, implant stability quotient (ISQ) values, histological observation, quantitative analysis of bone histomorphometry, and hematoxylin-eosin (HE) and Masson staining were evaluated...
October 16, 2018: Implant Dentistry
Simone Vargas Bento, Tarcizo Afonso Nunes, Ivana Durval Araújo, Roberto Carlos Oliveira E Silva, Paula Vieira Teixeira Vidigal, Ricardo Machado Carvalhais
PURPOSE: To evaluate the effects of hyperbaric oxygenation on prevention of adhesions in the abdominal cavity after laparotomy. METHODS: Fifty four rats underwent laparotomy; stitches were made in the four quadrant parietal peritoneum and abdominal cavity closure. Animals were divided into three groups: 1 - control; 2 - subjected to high pressures and oxygenation; 3 - subjected to 100% hyperbaric oxygenation. The animals in groups 2 and 3 were daily submitted to oxygenation hyperbaric chamber after surgery...
September 2018: Acta Cirúrgica Brasileira
Petra Anheuser, Sandra Mühlstädt, Jennifer Kranz, Laila Schneidewind, Joachim Steffens, Paolo Fornara
INTRODUCTION: Hyperbaric oxygenation (HBO), in addition to anti-infective and surgical therapy, seems to be a key treatment point for Fournier's gangrene. The aim of this study was to investigate the influence of HBO therapy on the outcome and prognosis of Fournier's gangrene. PATIENTS AND METHODS: In the present multicenter, retrospective observational study, we evaluated the data of approximately 62 patients diagnosed with Fournier's gangrene between 2007 and 2017...
October 16, 2018: Urologia Internationalis
Burak Eryigit, Fuat Ziylan, Furkan Yaz, Hans G X M Thomeer
OBJECTIVE: To evaluate the effectiveness of hyperbaric oxygen in the treatment of patients with idiopathic sudden sensorineural hearing loss (ISSHL). DATA SOURCES: An Embase, MEDLINE and Cochrane search were utilised to identify various clinical trials on the treatment of ISSHL. Studies that were published between 2002 and 2018 and written in the English, Dutch or German language were included. Search terms included synonyms for idiopathic sudden hearing loss. DATA SYNTHESIS: A total of 16 articles were identified regarding hyperbaric oxygen therapy...
October 15, 2018: European Archives of Oto-rhino-laryngology
Lauren C Nigro, Michael J Feldman, Nadia P Blanchet
Burns to breast reconstructions, both autologous and implant-based, are well described in the plastic surgery literature. The mechanism has often been contact; however, burns secondary to sun exposure have also been reported. With the increasing number of prepectoral breast reconstructions, including irradiated prepectoral reconstructions, we would like to highlight the increased susceptibility of these reconstructions to thermal and ultraviolet injury. We present the case of a patient who underwent prepectoral implant-based breast reconstruction years after irradiation, who subsequently developed full-thickness injury to her mastectomy flap after minor sun exposure...
August 2018: Plastic and Reconstructive Surgery. Global Open
Kaitlin Graham, Evan Unger
Hypoxia exists to some degree in most solid tumors due to inadequate oxygen delivery of the abnormal vasculature which cannot meet the demands of the rapidly proliferating cancer cells. The levels of oxygenation within the same tumor are highly variable from one area to another and can change over time. Tumor hypoxia is an important impediment to effective cancer therapy. In radiotherapy, the primary mechanism is the creation of reactive oxygen species; hypoxic tumors are therefore radiation resistant. A number of chemotherapeutic drugs have been shown to be less effective when exposed to a hypoxic environment which can lead to further disease progression...
2018: International Journal of Nanomedicine
Chien-Cheng Huang, Chung-Han Ho, Yi-Chen Chen, Chien-Chin Hsu, Yi-Fong Wang, Hung-Jung Lin, Jhi-Joung Wang, How-Ran Guo
The purpose of this study was to evaluate the effects of hyperbaric oxygen therapy (HBOT) on reducing neurological sequelae (NS) in patients with carbon monoxide poisoning (COP). Using a nationwide database of insurance claims in Taiwan, we conducted a population-based cohort study to identify 24,046 patients with COP diagnosed between 1999 and 2012, including 6793 (28.2%) patients who received HBOT and 17,253 (71.8%) patients who did not. We followed the two cohorts of patients and compared the occurrence of NS...
October 13, 2018: Journal of Clinical Medicine
Abbas Sedighinejad, Bahram Naderi Nabi, Hossein Ettehad, Ahmadreza Mirbolook, Zahra Atrkarroushan, Samaneh Ghazanfar Tehran, Gelareh Biazar, Mohammad Haghighi
Background: Hip fracture is one of the most common problems in elderly that needs surgical repair. As, the majority of these patients have chronic diseases, they are at increased risk of peri-operative mortality and morbidity. The purpose of this study was to evaluate spinal anesthesia with bupivacaine vs bupivacaine in combination with lidocaine in terms of hemodynamic changes in patients undergoing hip fracture surgery. Methods: This double-blind clinical trial was conducted on 292 patients undergoing surgery for hip fracture under spinal anesthesia...
September 2018: Archives of Bone and Joint Surgery
Ajit C Kulkarni, Krishnan Srinivasan
Introduction: Tunnel boring machine (TBM) is used for constructing a tunnel. Worn out cutting tools have to be changed under difficult working conditions. Temperature is high and the work is strenuous. Work is often carried out under increased atmospheric pressure to ward off water ingress. Workers are at a very high risk. Aim: To evaluate heat stress during hyperbaric intervention on TBM during Chennai Metro Rail construction. Methodology: One hundred and eighty-eight miners after a thorough medical examination worked under increased atmospheric pressure for more than 45,000 man hours...
May 2018: Indian Journal of Occupational and Environmental Medicine
Waqas Alam, Khan Muhammad Yaqub, Mobasher Ahmad Saeed
OBJECTIVE: To determine frequency of maternal hypotension during spinal anaesthesia for elective caesarean section by comparing fixed dose with height and weight-adjusted dose of hyperbaric 0.5% bupivacaine. METHODS: This randomised controlled trial was carried out at Pakistan Naval Ship Shifa Hospital, Karachi, and comprised patients with singleton pregnancy who were randomly divided into two groups. After preloading with 10ml/kg of Ringers lactate, Group A received fixed dose of 10mg of 0...
September 2018: JPMA. the Journal of the Pakistan Medical Association
Paulo Jorge Figueira, Diogo Alpuim Costa, Nunzio Barbagallo, Francisco Gamito Guerreiro
Kienböck's disease is a rare condition characterised by avascular necrosis of the lunate bone. Its natural history and aetiopathogenesis have not yet been clarified, nor are its triggering factors identified. We present a case of a 17-year-old male gymnast, without relevant medical/family history, with stage IIIA Kienböck's disease diagnosed in 2016. Initially, submitted to conservative treatment that proved to be insufficient. Consequently, surgical treatment was proposed, but refused. The patient instead underwent experimental treatment with hyperbaric oxygen (120 sessions, 100% oxygen at 2...
October 12, 2018: BMJ Case Reports
Kamonwan Jenwitheesuk, Ajanee Mahakkanukrauh, Wiyada Punjaruk, Kriangsak Jenwitheesuk, Bowornsilp Chowchuen, Suthin Jinaporntham, Krittinant Uraiwan, Phasuk Limrattanapimpa
Osteoradionecrosis (ORN) is a common consequence resulting from radiation in patients with cancer. Presently, hyperbaric oxygen therapy (HBOT) is proposed to have a role in improving wound healing in ORN patients. There is no strong scientific evidence to confirm the benefits of HBOT for treatment of ORN as an adjunctive treatment. This study aimed to determine the benefits of adjunctive treatment of HBOT in ORN. A retrospective study was conducted at the Srinagarind Hospital, the Faculty of Medicine, Khon Kaen University, Thailand, between 2011 and 2017...
2018: BioResearch Open Access
Pedro Henrique de Azambuja Carvalho, Lucas Borin Moura, Mario Francisco Real Gabrielli, Marisa Aparecida Cabrini Gabrielli, Valfrido Antonio Pereira Filho
Osteopetrosis is a rare condition which presents increased bone density and deficient bone remodeling. The consequential complications include cranial nerve impairment due compression, bone fractures, and osteomyelitis. Maxillary osteomyelitis is uncommon even in osteopetrosis patients. This is a systematic review of the literature regarding the management and outcomes of maxillary osteomyelitis in patients with autosomal dominant osteopetrosis (ADO) type II. A case of this specific pathology is reported. There are 18 cases of maxillary osteomyelitis associated with ADO type II reported in the literature...
September 24, 2018: Journal of Cranio-maxillo-facial Surgery
Kou-Gi Shyu, Bao-Wei Wang, Chun-Ming Pan, Wei-Jen Fang, Chiu-Mei Lin
BACKGROUND: Hyperbaric oxygen (HBO) could improve wound healing by enhancement of angiogenesis. The effect of HBO on metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a proangiogenic long noncoding RNA, and on endothelial cell-derived exosome is unknown. We aim to investigate both whether MALAT1 is altered in human coronary artery endothelial cells (HCAECs)-derived exosomes in response to HBO as well as the molecular regulatory mechanisms of MALAT1 in HCAECs under HBO treatment...
October 2, 2018: International Journal of Cardiology
Seiji Hosokawa, Kumiko Hosokawa, Goro Takahashi, Ken-Ichi Sugiyama, Hiroshi Nakanishi, Satoru Takebayashi, Hiroyuki Mineta
We analyzed 356 patients with idiopathic sudden sensorineural hearing loss treated with hyperbaric oxygen therapy and systemic steroids (n = 161), systemic steroids alone (n = 160), or intratympanic and systemic steroids (n = 35). The main outcome measure was the hearing recovery rate. The effect of other variables, including the initial averaged 5-frequency hearing level, patient age, interval between the onset of symptoms and treatment, presence of vertigo as a complication, presence of diabetes mellitus, smoking history, and presence of hypertension, on the hearing recovery rate was also evaluated...
October 9, 2018: Audiology & Neuro-otology
Wei-Chih Liao, Wen-Chien Cheng, Biing-Ru Wu, Wei-Chun Chen, Chih-Yu Chen, Chia-Hung Chen, Chih-Yen Tu, Te-Chun Hsia
BACKGROUND: Carbon monoxide (CO), a colorless and odorless gas, is one of the common causes of poisoning-related deaths worldwide. CO poisoning can result in hypoxic brain damage and death, but intensive care can improve the likely outcome for critically ill patients. However, there is a paucity of clinical data regarding the prognostic factors and association between organ dysfunction and clinical outcome of patients treated for CO poisoning in the intensive care unit (ICU). METHODS: We performed a retrospective study of patients admitted to a university affiliated hospital ICU between July 2001 and December 2010 following CO poisoning...
October 5, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
Rani Abu Eta, Haim Gavriel, Kleid Stephen, Ephraim Eviatar, Eyal Yeheskeli
INTRODUCTION: The conventional treatment for necrotizing otitis externa (NOE) is prolonged anti-pseudomonas therapy, with surgical treatment in non-responsive patients. The aim of the present study is to describe the course of management of patients with non-responsive NOE undergoing hyperbaric oxygen therapy (HBOT), and to investigate the importance of tissue biopsy for fungi in this group of patients. MATERIALS AND METHODS: A retrospective study conducted between January 2010 and December 2013 at an Otolaryngology Head and Neck Surgery Department...
October 5, 2018: European Archives of Oto-rhino-laryngology
Claire Harris, Mercedeh Kiaii, Wynnie Lau, Myriam Farah
Background: Calcific uremic arteriolopathy (CUA), also known as calciphylaxis, is a rare but life-threatening condition predominately occurring in patients with end-stage renal disease on dialysis. In the absence of randomized clinical trials to guide management, clinicians must rely on observational data. We have previously reported the outcomes of our multi-intervention management in seven patients and now present a larger series of patients with extended follow-up. Methods: We performed a retrospective analysis of all patients diagnosed with CUA at a single academic center between 2008 and 2017...
October 2018: Clinical Kidney Journal
Fikret Salik, Ebru Tarikçi Kiliç, Hakan Akelma, Abdülmenap Güzel
Aim: Spinal anesthesia is a widely used procedure in modern anesthesia. Although it is a reliable and frequently used anesthetic procedure, it involves complications, including postdural puncture headache caused by arachnoid punctured, which significantly affects postoperative well-being. In this study, we aimed to observe headache frequency with 26-G Quincke spinal needle in either transverse or sagittal planes. Materials and Methods: One hundred patients with American Society of Anesthesiologists status classes I and II who were scheduled for elective cesarean delivery with no contraindications for performing spinal anesthesia were randomly divided into two groups: Group I (transverse n = 50) and Group II (sagittal n = 50)...
July 2018: Anesthesia, Essays and Researches
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