keyword
https://read.qxmd.com/read/37792637/short-course-radiation-with-consolidation-chemotherapy-does-not-increase-operative-morbidity-compared-to-long-course-chemoradiation-a-retrospective-study-of-the-us-rectal-cancer-consortium
#21
JOURNAL ARTICLE
Philip S Bauer, Adriana C Gamboa, Ebunoluwa E Otegbeye, William C Chapman, Samantha Rivard, Scott Regenbogen, Maryam Mohammed, Jennifer Holder-Murray, Jason T Wiseman, Aslam Ejaz, Kamren Edwards-Hollingsworth, Alexander T Hawkins, Steven R Hunt, Glen Balch, Matthew L Silviera
BACKGROUND AND OBJECTIVES: Neoadjuvant short-course radiation and consolidation chemotherapy (SC TNT) remains less widely used for rectal cancer in the United States than long-course chemoradiation (LCRT). SC TNT may improve compliance and downstaging; however, a longer radiation-to-surgery interval may worsen pelvic fibrosis and morbidity with total mesorectal excision (TME). A single, US-center retrospective analysis has shown comparable risk of morbidity after neoadjuvant short-course radiation with consolidation chemotherapy (SC TNT) and long-course chemoradiation (LCRT)...
October 4, 2023: Journal of Surgical Oncology
https://read.qxmd.com/read/37739696/parenteral-nutrition-after-cytoreductive-surgery-for-peritoneal-malignancy-should-it-be-administered-routinely
#22
JOURNAL ARTICLE
Ayman Khan, Anna Beaumont, Erin Laing, Glen Guerra, Anshini Jain, Satish Warrier, Alexander Heriot
PURPOSE/BACKGROUND: Cytoreductive surgery (CRS) is complex abdominal surgery that is used to treat peritoneal malignancy. CRS is associated with major morbidity and efforts to address this include optimisation of perioperative care. There is variation in international protocols on the nutritional management after CRS, in particular whether parenteral nutrition (PN) should be routinely or selectively administered. HYPOTHESIS/AIM: This study assessed parenteral nutrition use, factors associated with PN requirement and nutritional outcomes in a centre that selectively uses PN after CRS...
October 2023: Clinical Nutrition ESPEN
https://read.qxmd.com/read/37710195/identifying-strategies-that-support-equitable-person-centred-osteoarthritis-care-for-diverse-women-content-analysis-of-guidelines
#23
JOURNAL ARTICLE
Chidinma Abuwa, Angelina Abbaticchio, Madeline Theodorlis, Deborah Marshall, Crystal MacKay, Cornelia M Borkhoff, Glen Stewart Hazlewood, Marisa Battistella, Aisha Lofters, Vandana Ahluwalia, Anna R Gagliardi
INTRODUCTION: Women are disproportionately impacted by osteoarthritis (OA) but less likely than men to access early diagnosis and management, or experience OA care tailored through person-centred approaches to their needs and preferences, particularly racialized women. One way to support clinicians in optimizing OA care is through clinical guidelines. We aimed to examine the content of OA guidelines for guidance on providing equitable, person-centred care to disadvantaged groups including women...
September 14, 2023: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/37704267/development-of-a-joint-set-of-database-parameters-for-the-eu-rop-and-fight-childhood-blindness-rop-registries
#24
JOURNAL ARTICLE
Caroline Catt, Johanna M Pfeil, Daniel Barthelmes, Glen A Gole, Tim U Krohne, Wei-Chi Wu, Shunji Kusaka, Peiquan Zhao, Shuan Dai, James Elder, Matthias Heckmann, Jacqueline Stack, Gigi Khonyongwa-Fernandez, Andreas Stahl
BACKGROUND/AIMS: The incidence of retinopathy of prematurity (ROP) is increasing and treatment options are expanding, often without accompanying safety data. We aimed to define a minimal, patient-centred data set that is feasible to collect in clinical practice and can be used collaboratively to track and compare outcomes of ROP treatment with a view to improving patient outcomes. METHODS: A multinational group of clinicians and a patient representative with expertise in ROP and registry development collaborated to develop a data set that focused on real-world parameters and outcomes that were patient centred, minimal and feasible to collect in routine clinical practice...
September 13, 2023: British Journal of Ophthalmology
https://read.qxmd.com/read/37689234/comparing-apples-to-apples-exploring-public-reporting-of-congenital-cardiac-surgery-outcomes-based-on-common-congenital-heart-operations
#25
JOURNAL ARTICLE
Meena Nathan, Kimberlee Gauvreau, Owen White, Brett R Anderson, Emile A Bacha, David J Barron, John Cleveland, Pedro J Del Nido, Pirooz Eghtesady, Mark Galantowicz, Andrea Kennedy, Katherine Kohlsaat, Michael Ma, Charlene Mattila, Glen Van Arsdell, J William Gaynor
OBJECTIVE: We sought to simplify reporting of outcomes in congenital heart surgery that compares well-defined patient groups, accommodates multiple stakeholder needs while being easily understandable. METHODS: We selected 19 commonly performed congenital heart surgeries ranging in complexity from repair of atrial septal defects (ASD) to the Norwood procedure. Strict inclusion/exclusion criteria ensured the creation of 19 well defined diagnosis/procedure cohorts...
September 7, 2023: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/37673437/continuity-of-primary-care-and-emergency-department-visits-following-knee-and-hip-replacement-surgery-a-retrospective-cohort-study
#26
JOURNAL ARTICLE
Lynn Lethbridge, C Glen Richardson, Michael J Dunbar
BACKGROUND: Continuity of primary care (CPC) improves patient well-being, but the association between CPC and surgical outcomes has not been well studied. The numbers of joint replacement procedures are expected to rise considerably in the coming years, so it is crucial to identify factors related to successful outcomes. The purpose of this study was to examine the association between CPC and emergency department (ED) visits after knee and hip replacement surgery. METHODS: Physician claims and hospital data from 2005 to 2020 in Nova Scotia were used in this retrospective study...
2023: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://read.qxmd.com/read/37616533/effects-of-high-intensity-eccentric-only-muscle-actions-on-serum-biomarkers-of-collagen-degradation-and-synthesis
#27
JOURNAL ARTICLE
Tyler J Neltner, Prakash K Sahoo, Robert W Smith, John Paul V Anders, Jocelyn E Arnett, Dolores G Ortega, Richard J Schmidt, Glen O Johnson, Sathish Kumar Natarajan, Terry J Housh
Neltner, TJ, Sahoo, PK, Smith, RW, Anders, JPV, Arnett, JE, Ortega, DG, Schmidt, RJ, Johnson, GO, Natarajan, SK, and Housh, TJ. Effects of high-intensity, eccentric-only muscle actions on serum biomarkers of collagen degradation and synthesis. J Strength Cond Res 37(9): 1729-1737, 2023-The purpose of this study was to examine the effects of high-intensity, eccentric-only muscle actions of the leg extensors on (a) serum biomarkers of collagen degradation (hydroxyproline [HYP] and C-terminal telopeptide of type I collagen [C1M]) and synthesis (pro-c1α1) and (b) the time course of changes in maximal voluntary isometric contraction (MVIC) and ratings of muscle soreness after the eccentric-only exercise bout...
September 1, 2023: Journal of Strength and Conditioning Research
https://read.qxmd.com/read/37616447/the-value-of-computer-assisted-navigation-for-glenoid-baseplate-implantation-in-reverse-shoulder-arthroplasty-a-systematic-review-and-meta-analysis
#28
JOURNAL ARTICLE
Ausberto Velasquez Garcia, Glen Abdo, Joaquin Sanchez-Sotelo, Mark E Morrey
BACKGROUND: Glenoid baseplate malpositioning during reverse total shoulder arthroplasty can contribute to perimeter impingement, dislocation, and loosening. Despite advances in preoperative planning, conventional instrumentation may lead to considerable inaccuracy in implant positioning unless patient-specific guides are used. Optical navigation has the potential to improve accuracy and precision when implanting a reverse shoulder arthroplasty baseplate. This systematic review aimed to analyze the most recent evidence on the accuracy and precision of glenoid baseplate positioning using intraoperative navigation and its potential impact on component selection and surgical time...
August 1, 2023: JBJS Reviews
https://read.qxmd.com/read/37585677/hyperbaric-oxygen-therapy-for-late-radiation-tissue-injury
#29
REVIEW
Zhiliang Caleb Lin, Michael H Bennett, Glen C Hawkins, Charles Paul Azzopardi, John Feldmeier, Robert Smee, Christopher Milross
BACKGROUND: This is the third update of the original Cochrane Review published in July 2005 and updated previously in 2012 and 2016. Cancer is a significant global health issue. Radiotherapy is a treatment modality for many malignancies, and about 50% of people having radiotherapy will be long-term survivors. Some will experience late radiation tissue injury (LRTI), developing months or years following radiotherapy. Hyperbaric oxygen therapy (HBOT) has been suggested as a treatment for LRTI based on the ability to improve the blood supply to these tissues...
August 15, 2023: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/37572544/the-long-term-effects-of-aggressive-spasticity-reducing-treatment-including-selective-dorsal-rhizotomy-on-joint-kinematic-outcomes-of-persons-with-cerebral-palsy
#30
JOURNAL ARTICLE
Mark L McMulkin, Bruce A MacWilliams, Elizabeth A Nelson, Meghan E Munger, Brian Po-Jung Chen, Tom F Novacheck, Kristen L Carroll, Alan K Stotts, Lisa H Carter, Shelley L Mader, Brianna Hayes, Glen O Baird, Michael H Schwartz
BACKGROUND: Selective dorsal rhizotomy (SDR) creates a large and permanent reduction of spasticity for children with cerebral palsy (CP). Previous SDR outcomes studies have generally lacked appropriate control groups, had limited sample sizes, or reported short-term follow-up, limiting evidence for improvement in long-term gait function. RESEARCH QUESTION: Does aggressive spasticity management for individuals with CP improve long-term gait kinematics (discrete joint kinematics) compared to a control group of individuals with CP with minimal spasticity management? METHODS: This study was a secondary analysis - focused on joint-level kinematics - of a previous study evaluating the long-term outcomes of SDR...
August 2, 2023: Gait & Posture
https://read.qxmd.com/read/37555030/pediatric-heart-transplantation-from-donation-after-circulatory-death-using-normothermic-regional-perfusion-and-cold-storage-from-a-distant-donor-first-us-experience
#31
Reshma Biniwale, Saba Lahar, Shyamasundar Balasubramanya, Carla Caraccio, Biliet Ngang, Heather Barone, Emily Stimpson, Kim Dela Cruz, Juan Carlos Alejos, Ryan Williams, Nancy Halnon, Leigh Reardon, Ming-Sing Si, Richard Shemin, Abbas Ardehali, Glen Van Arsdell
No abstract text is available yet for this article.
August 2023: JTCVS techniques
https://read.qxmd.com/read/37551939/preferred-definitive-surgical-management-of-crohn-s-perianal-fistulas-and-factors-influencing-surgical-decision-making-in-australia-and-new-zealand
#32
JOURNAL ARTICLE
Michael De Gregorio, Ankur Sidhu, Cori Behrenbruch, Susan J Connor, Glen Guerra, Michael J Johnston, James O Keck, Eugene J S K Ong, Alexander J Thompson, Rodney Woods, Basil D'Souza, Nik S Ding
No abstract text is available yet for this article.
August 8, 2023: ANZ Journal of Surgery
https://read.qxmd.com/read/37488985/aga-practitioner-challenges-a-mixed-methods-pilot-survey
#33
JOURNAL ARTICLE
Glen S Jankowski, Dirk Kranz
BACKGROUND: Androgenetic alopecia (AGA) practitioner care may be hampered by commercial biases and hair loss' omission from most medical curricula. AIM AND METHOD: Between November 2020 and September 2021, 34 AGA professionals (86% British; 62% trichologists), participated in a pilot, mixed-methods, survey. Practitioner views on: 1a-1j) AGA's commercial influences (e.g., participants were quantitatively assessed on their understanding of a popular, commercially-funded, AGA study) and 2a-2h) constraints on evidenced-based AGA responding (e...
July 24, 2023: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/37458131/close-distal-margin-is-associated-with-locoregional-rectal-cancer-recurrence-a-multicenter-study
#34
JOURNAL ARTICLE
Christopher J Varlamos, Brandy Sinco, Inga Van Weiren, Scott Regenbogen, Adriana C Gamboa, Matthew Silviera, Sherif R Z Abdel-Misih, Alexander T Hawkins, Glen Balch, Samantha Hendren
BACKGROUND AND OBJECTIVES: The importance of the radial margin for rectal cancer resection is well understood. However, surgeons have deemphasized the distal margin, accepting very close distal margins to perform sphincter-preserving surgery. We hypothesized that distal margins < 1 cm would be an independent risk factor for locoregional recurrence. The objective was to determine whether close distal margins are associated with increased locoregional recurrence risk...
July 17, 2023: Journal of Surgical Oncology
https://read.qxmd.com/read/37399478/the-use-of-preoperative-antibiotics-in-hardware-based-hand-procedures-is-not-necessary-a-single-surgeon-experience
#35
JOURNAL ARTICLE
Emma S Dahmus, Katie Frank, Glen Jacob
BACKGROUND: A survey to American Society for Surgery of the Hand members by Dunn et al showed that the use of preoperative antibiotics was random and not standardized for all hand procedures (Hand (N Y). 2020;15(4):534-541). Previous publications support that preoperative antibiotics for clean, soft-tissue procedures are not necessary, but there is minimal evidence regarding the need for preoperative antibiotics for hardware-based hand procedures. The purpose of our study is to compare infectious outcomes for patients undergoing hardware-based hand surgery between those who did and those who did not receive preoperative antibiotics...
June 1, 2023: Annals of Plastic Surgery
https://read.qxmd.com/read/37326447/systemic-diclofenac-sodium-reduces-post-operative-rhbmp-2-induced-neuroinflammation-a-rodent-model-study
#36
JOURNAL ARTICLE
Glen Liau Zi Qiang, Sherry Liu Jiani, Wing Moon Raymond Lam, Jiayi Weng, Lucius Ho Kang Hua, Louise Kok, Syeda Fabeha Husain, Ling Liu, Sanjay Khanna, Hee Kit Wong
STUDY DESIGN: This is a basic science, animal research study. OBJECTIVE: This study aims to explore, in rodent models, the effectiveness of systemic non-steroidal anti-inflammatory drugs (NSAIDs) in reducing recombinant human bone morphogenetic protein-2 (rhBMP-2) induced neuro-inflammation. SUMMARY OF BACKGROUND DATA: rhBMP-2 is increasingly used to augment fusion in lumbar interbody fusion surgeries, although it can cause complications including post-operative radiculitis...
June 16, 2023: Spine
https://read.qxmd.com/read/37307671/hybrid-approach-for-treatment-of-a-symptomatic-giant-splenic-artery-aneurysm
#37
JOURNAL ARTICLE
Kevin Connors, Rebecca Allen, Mackenzie Snyder, Glen Gibson, Geetha Jeyabalan
A 56-year-old female presented with a symptomatic giant fusiform mid-splenic artery aneurysm (7.3 x 6.4 cm). The patient underwent hybrid management of the aneurysm with endovascular embolization of the aneurysm and inflow splenic artery followed by laparoscopic splenectomy with control and division of the outflow vessels. The patient had an uneventful post-operative course. This case demonstrates the safety and efficacy of an innovative, hybrid management of a giant splenic artery aneurysm with endovascular embolization and laparoscopic splenectomy that spares the pancreatic tail...
June 12, 2023: Vascular and Endovascular Surgery
https://read.qxmd.com/read/37215300/acute-colonic-perforation-with-septic-shock-secondary-to-disseminated-histoplasmosis-in-an-autologous-bone-marrow-transplant-recipient
#38
Harsimrandeep Bhatti, Enkhbileg Batbileg, Srijisnu De, Glen Friedman, Suresh Antony
Histoplasma capsulatum is an opportunistic pathogen which can lead to a wide variety of clinical presentations in the immunocompromised host. Post-transplant histoplasmosis in hematopoietic cell transplant recipients is exceedingly rare, with an incidence of <1%. We present a case of acute caecal perforation resulting from disseminated histoplasmosis in a patient who had undergone autologous bone marrow transplant for plasma cell dyscrasia. This is a 71-year-old patient who initially presented due to progressive weakness associated with shortness of breath...
2023: Infection and Drug Resistance
https://read.qxmd.com/read/37178960/scaffold-and-graft-based-biologic-augmentation-of-rotator-cuff-repair-an-updated-systematic-review-meta-analysis-of-pre-clinical-and-clinical-studies-for-2010-2022
#39
REVIEW
Krishna Mandalia, Albert Mousad, Benjamin Welborn, Olivia Bono, Stephen Le Breton, Meghan MacAskill, Julianne Forlizzi, Katharine Ives, Glen Ross, Sarav Shah
BACKGROUND: Despite advancements in the surgical techniques of rotator cuff repair (RCR), there remains a high retear rate. Biological augmentation of repairs with overlaying grafts and scaffolds may enhance healing and strengthen the repair construct. This study aimed to investigate the efficacy and safety of scaffold (non-structural) and non-superior capsule reconstruction & non-bridging overlay graft-based (structural) biologic augmentation in RCR, in both pre-clinical and clinical studies...
May 11, 2023: Journal of Shoulder and Elbow Surgery
https://read.qxmd.com/read/37159280/sleep-subdomain-of-the-sinonasal-outcome-test-as-a-potential-screening-tool-for-sleep-apnea-in-chronic-rhinosinusitis
#40
JOURNAL ARTICLE
Alexander N Duffy, Rahul Alapati, Chandala Chitguppi, Glen D'Souza, Sean M Parsel, Elina M Toskala, Marc R Rosen, Gurston G Nyquist, Mindy R Rabinowitz
OBJECTIVES: Approximately 20% of patients with chronic rhinosinusitis (CRS) have comorbid obstructive sleep apnea (OSA). Patients with undiagnosed OSA are at high risk for perioperative complications. The Sinonasal Outcomes Test (SNOT-22) Questionnaire is commonly administered to CRS patients, whereas OSA screening tools are less routinely employed. This study compared SNOT-22 sleep subdomain (Sleep-SNOT) scores among non-OSA CRS versus OSA-CRS patients undergoing ESS, and assessed sensitivity, specificity, and diagnostic accuracy of the Sleep-SNOT for OSA screening...
May 9, 2023: Laryngoscope
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