keyword
https://read.qxmd.com/read/38395246/antimicrobial-photodynamic-therapy-against-a-dual-species-cariogenic-biofilm-using-a-ruthenium-loaded-resin-based-dental-material
#21
JOURNAL ARTICLE
Maria Luísa Leite, Patricia Comeau, Sana Aghakeshmiri, Dirk Lange, Lidiany Karla Azevedo Rodrigues, Neil Branda, Adriana Pigozzo Manso
BACKGROUND: Streptococcus mutans and Candida albicans are associated with caries recurrence. Therefore, this study evaluated the combination of a Ru(II)-loaded resin-based dental material (RDM) and antimicrobial photodynamic therapy (aPDT) against a dual-species biofilm of S. mutans and C. albicans. METHODS: An aPDT protocol was established evaluating Ru(II)'s photocatalytic activity and antimicrobial potential under blue LED irradiation (440-460 nm, 22.55 mW/cm2 ) at different energy densities (0...
February 21, 2024: Photodiagnosis and Photodynamic Therapy
https://read.qxmd.com/read/38394062/caries-indicators-in-relation-to-healthcare-access-and-hygienic-dietary-habits-in-spanish-preschoolers
#22
JOURNAL ARTICLE
Beatriz Prieto-Regueiro, Gladys Gómez-Santos, Guillermo Reichard-Monefeldt, Montserrat Diéguez-Pérez
INTRODUCTION: Dental caries continues to be a public healthcare problem due to its high prevalence and morbidity. It was proposed to evaluate caries indicators in relation to healthcare access and hygienic-dietary habits in Spanish preschoolers. MATERIALS AND METHODS: A cross-sectional study was carried out on a random sample consisting of 343 patients ranging from 3 to 5 years of age in the primary care setting, the main measurements were: dental care access, hygienic-dietary habits, and caries registration according to WHO criteria...
February 23, 2024: International Journal of Dental Hygiene
https://read.qxmd.com/read/38392244/pine-oil-derived-sodium-resinate-inhibits-growth-and-acid-production-of-streptococcus-mutans-in-vitro
#23
JOURNAL ARTICLE
Otto Rajala, Matias Mäntynen, Vuokko Loimaranta
S. mutans is a key pathogen in dental caries initiation and progression. It promotes oral biofilm dysbiosis and biofilm acidification. Sodium resinate is a salt of pine-oil-derived resin which has antimicrobial properties. Pine-oil-derived resin consists of terpenes, diterpenes, and abietic acids. The aim of this study was to determine the effects of pine ( Pinus sylvestris ) oil resinate (RS) on growth and acid production of cariogenic S. mutans strains in planktonic form and biofilm. The S. mutans type strain NCTC10449 and clinical isolate CI2366 were grown on 96-well plates for testing of RS effects on growth and biofilm formation, and on plates with integrated pH-sensitive optical ensors for real-time measurements of the effects of RS on bacterial acid production...
February 17, 2024: Dentistry Journal
https://read.qxmd.com/read/38388987/the-effect-of-nano-silver-fluoride-self-assembling-peptide-and-sodium-fluoride-varnish-on-salivary-cariogenic-bacteria-a-randomized-controlled-clinical-trial
#24
JOURNAL ARTICLE
Sara M Atteya, Hala A Amer, Susan M Saleh, Yara Safwat
OBJECTIVES: To compare the antibacterial effect of Nanosilver Fluoride varnish (NSF) varnish, P11-4 and Sodium Fluoride (NaF) varnish against salivary Streptococcus mutans (S. mutans) and Lactobacilli. METHODS: 66 patients aged 10-24 years old were randomly assigned to receive single application of NSF, P11-4 or NaF varnish. Baseline unstimulated saliva samples were collected before the agents were applied and S.mutans and Lactobacilli colony forming units (CFU) were counted...
February 23, 2024: Clinical Oral Investigations
https://read.qxmd.com/read/38376433/cariogenic-diet-assessment-and-analysis-tools-in-children-and-adolescents-a-systematic-review
#25
JOURNAL ARTICLE
Matina V Angelopoulou, Kyriaki Seremidi, Vasiliki Benetou, Andreas Agouropoulos, Christos Rahiotis, Sotiria Gizani
PURPOSE: To collect and evaluate the available evidence on existing tools used in research and clinical practice to assess and analyse the diet of children and adolescents for its cariogenicity. MATERIALS AND METHODS: Multiple databases were searched up to October 2022, with no date, publication, or language restrictions, followed by a manual search. Study screening, data extraction, and risk of bias assessment were performed in duplicate. Dietary assessment tools and dental clinical parameters tested were retrieved for qualitative assessment and synthesis...
January 15, 2024: Oral Health & Preventive Dentistry
https://read.qxmd.com/read/38364699/human-prh1-prh2-susceptibility-and-resistance-and-streptococcus-mutans-virulence-phenotypes-specify-different-microbial-profiles-in-caries
#26
JOURNAL ARTICLE
Nongfei Sheng, Lena Mårell, Raviprakash Tumkur Sitaram, Gunnel Svensäter, Anna Westerlund, Nicklas Strömberg
BACKGROUND: Lifestyle- and sucrose-dependent polymicrobial ecological shifts are a primary cause of caries in populations with high caries prevalence. In populations with low prevalence, PRH1, PRH2 susceptibility and resistance phenotypes may interact with the Streptococcus mutans adhesin cariogenicity phenotype to affect caries progression, but studies are lacking on how these factors affect the microbial profile of caries. METHODS: We analysed how the residency and infection profiles of S...
February 15, 2024: EBioMedicine
https://read.qxmd.com/read/38342921/evaluation-of-possible-associated-factors-for-early-childhood-caries-are-preterm-birth-and-birth-weight-related
#27
JOURNAL ARTICLE
Merve Bilmez Selen, Pınar Demir, Feyza Inceoglu
BACKGROUND: This study aimed to evaluate the oral and dental health of preschool children aged 12-71 months living in the Eastern Anatolia Region of Turkey, and to examine the effects of low birth weight (LBW) and preterm, early term and term birth on dental caries. METHODS: 475 participants were included in the study. Intraoral examinations were performed and evaluated for the presence of early childhood caries (ECC). These values ​​are; Relationships such as age, gender, birth weight, week of birth, tooth brushing frequency, cariogenic nutrition, and parental education levels were examined...
February 11, 2024: BMC Oral Health
https://read.qxmd.com/read/38341538/unlocking-the-potential-of-probiotic-administration-in-caries-management-a-systematic-review
#28
JOURNAL ARTICLE
Pedro C Lopes, Ana T P C Gomes, Karina Mendes, Letícia Blanco, Maria J Correia
BACKGROUND: The use of prebiotics and/or probiotic bacteria with the potential to modulate the oral ecosystem may play an important role in the prevention and management of dental caries. To assess the evidence of the potential of pre/probiotics both in the prevention and treatment of dental caries, we focused on the PICO question "In individuals with caries, after probiotic administration, is there an improvement in outcomes directly related to caries risk and development?". METHODS: An extensive systematic search was conducted in electronic databases PubMed, Web of Science, Scopus and Cochrane, to identify articles with relevant data...
February 10, 2024: BMC Oral Health
https://read.qxmd.com/read/38338734/assessment-of-the-salivary-concentrations-of-selected-immunological-components-in-adult-patients-in-the-late-period-after-allogeneic-hematopoietic-stem-cell-transplantation-a-translational-study
#29
JOURNAL ARTICLE
Aniela Brodzikowska, Barbara Kochańska, Agnieszka Bogusławska-Kapała, Izabela Strużycka, Bartłomiej Górski, Andrzej Miskiewicz
(1) The aim of the study was to analyze the salivary concentrations of lysozyme, lactoferrin, and sIgA antibodies in adult patients in the late period after allogeneic stem cell transplantation (alloHSCT). The relationship between these concentrations and the salivary secretion rate and the time elapsed after alloHSCT was investigated. The relationship between the concentrations of lysozyme, lactoferrin, and sIgA and the titer of the cariogenic bacteria S. mutans and L. acidophilus was assessed. (2) The study included 54 individuals, aged 19 to 67 (SD = 40...
January 25, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38331426/time-lapse-confocal-microscopy-to-study-in-vitro-streptococcus-mutans-surface-colonization
#30
JOURNAL ARTICLE
J T F Wing, M A L Hayashi, A F Redissi, M M Vickerman, L M A Tenuta, J C Fenno, A H Rickard
The cariogenicity of Streptococcus mutans relates to its ability to form biofilms on dental surfaces. The aim of this work was to develop a flowcell system compatible with time-lapse confocal microscopy to compare the adhesion and accumulation of S. mutans cells on surfaces in unsupplemented media against media containing sucrose or sucralose (a non-metabolized sweetener) over a short period of time. Fluorescent S. mutans 3209/pVMCherry was suspended in un-supplemented media or media supplemented with 1% sucrose or 1% sucralose and passed through a 3D printed flowcell system...
February 8, 2024: Letters in Applied Microbiology
https://read.qxmd.com/read/38328472/metagenomic-analysis-of-bacterial-microflora-in-dental-and-atherosclerotic-plaques-of-patients-with-internal-carotid-artery-stenosis
#31
JOURNAL ARTICLE
Ayako Sato, Shintaro Arai, Kenji Sumi, Haruka Fukamachi, Satoko Miyake, Manami Ozawa, Mie Myers, Yasubumi Maruoka, Katsuyoshi Shimizu, Tohru Mizutani, Hirotaka Kuwata
BACKGROUND: Internal carotid artery stenosis is primarily attributed to atherosclerosis in the carotid artery bifurcation. Previous studies have detected oral bacteria in atherosclerotic lesions, suggesting an association between oral bacteria and atherosclerosis. In this study, we compared the bacterial flora of the atherosclerotic plaque in the carotid artery and dental plaque of patients with internal carotid artery stenosis using 16S ribosomal RNA (16S rRNA) metagenomic sequencing...
2024: Clinical Medicine Insights. Cardiology
https://read.qxmd.com/read/38319113/human-saliva-modifies-growth-biofilm-architecture-and-competitive-behaviors-of-oral-streptococci
#32
JOURNAL ARTICLE
Allen Choi, Kevin Dong, Emily Williams, Lindsey Pia, Jordan Batagower, Paige Bending, Iris Shin, Daniel I Peters, Justin R Kaspar
The bacteria within supragingival biofilms participate in complex exchanges with other microbes inhabiting the same niche. One example is the mutans group streptococci ( Streptococcus mutan s), implicated in the development of tooth decay, and other health-associated commensal streptococci species. Previously, our group transcriptomically characterized intermicrobial interactions between S. mutans and several species of oral bacteria. However, these experiments were carried out in a medium without human saliva...
February 6, 2024: MSphere
https://read.qxmd.com/read/38304119/manipulating-the-diseased-oral-microbiome-the-power-of-probiotics-and-prebiotics
#33
REVIEW
X Yu, D A Devine, J J Vernon
Dental caries and periodontal disease are amongst the most prevalent global disorders. Their aetiology is rooted in microbial activity within the oral cavity, through the generation of detrimental metabolites and the instigation of potentially adverse host immune responses. Due to the increasing threat of antimicrobial resistance, alternative approaches to readdress the balance are necessary. Advances in sequencing technologies have established relationships between disease and oral dysbiosis, and commercial enterprises seek to identify probiotic and prebiotic formulations to tackle preventable oral disorders through colonisation with, or promotion of, beneficial microbes...
2024: Journal of Oral Microbiology
https://read.qxmd.com/read/38302447/the-antimicrobial-activity-of-theobromine-against-cariogenic-microbes-an-in-vitro-pilot-study
#34
JOURNAL ARTICLE
Ismaeel H Rafiq, Naile Dame-Teixeira, Thuy Do
OBJECTIVE: This pilot study aimed to compare the antimicrobial effect of theobromine, sodium fluoride, and a theobromine-sodium fluoride combination against the following caries-associated bacteria: Streptococcus mutans and Actinomyces naeslundii. METHODOLOGY: Antimicrobial susceptibility was tested via the broth microdilution method, with suspensions cultured on each microbe's respective selective media. Shapiro-Wilk's was completed and all the data showed normality (p > 0...
February 1, 2024: BDJ Open
https://read.qxmd.com/read/38296118/comparative-evaluation-of-anti-biofilm-and-anti-adherence-potential-of-plant-extracts-against-streptococcus-mutans-a-therapeutic-approach-for-oral-health
#35
JOURNAL ARTICLE
Preeti Pallavi, Pragnya Paramita Sahoo, Sudip Kumar Sen, Sangeeta Raut
Dental caries predominantly attributed to the cariogenic nature of Streptococcus mutans, continue to pose a substantial global challenge to oral health. In response to this challenge, this study aimed to evaluate the effectiveness of leaf extracts (LEs) and essential oils (EOs) derived from different medicinal plants in inhibiting the formation of Streptococcus mutans biofilm. In vitro and in silico approaches were employed to identify active compounds and assess their inhibitory effects on S. mutans. Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were measured to determine the anti-biofilm and anti-adherence activity against S...
January 29, 2024: Microbial Pathogenesis
https://read.qxmd.com/read/38293214/fluoride-export-is-required-for-competitive-fitness-of-pathogenic-microorganisms-in-dental-biofilm-models
#36
Aditya Banerjee, Chia-Yu Kang, Minjun An, B Ben Koff, Sham Sunder, Anuj Kumar, Livia M A Tenuta, Randy B Stockbridge
UNLABELLED: Microorganisms resist fluoride toxicity using fluoride export proteins from one of several different molecular families. Cariogenic species Streptococcus mutans and Candida albicans extrude intracellular fluoride using a CLC F F - /H + antiporter and FEX fluoride channel, respectively, whereas commensal eubacteria, such as Streptococcus gordonii, export fluoride using a Fluc fluoride channel. In this work, we examine how genetic knockout of fluoride export impacts pathogen fitness in single-species and three-species dental biofilm models...
January 18, 2024: bioRxiv
https://read.qxmd.com/read/38289762/dental-caries-on-deciduous-molars-among-children-visiting-dental-outpatient-department-of-a-tertiary-care-centre
#37
JOURNAL ARTICLE
Bhoj Raj Adhikari, Mamata Shakya, Nisha Bhatta, Sumita Upadhya, Swagat Kumar Mahanta
INTRODUCTION: Dental caries is one of the most common, yet preventable childhood diseases. The aetiology of dental caries lies in the interplay between host, microorganism, substrate, and time. Risk factors for dental caries include physical, biological, environmental, behavioural, and lifestyle-related factors such as high numbers of cariogenic bacteria, inadequate salivary flow, insufficient fluoride exposure, poor oral hygiene, inappropriate methods of feeding infants, and poverty...
December 1, 2023: JNMA; Journal of the Nepal Medical Association
https://read.qxmd.com/read/38287750/knowledge-and-attitude-towards-children-s-oral-health-findings-from-a-sample-of-first-time-mothers-in-malaysia
#38
JOURNAL ARTICLE
W M Wan Abdul Rahman, N Saddki, Z Mahmood, R Hasan, N A Samsudin
INTRODUCTION: Women's important roles within families which include modelling appropriate oral health behaviours require them to have good knowledge and positive attitude in oral health. This study determined knowledge and attitude towards children's oral health among first-time mothers and factors associated with the attributes. MATERIALS AND METHODS: A total of 154 first-time mothers in the third trimester of pregnancy who attended two health clinics in the state of Sarawak, Malaysia for antenatal care participated in this cross-sectional study...
January 2024: Medical Journal of Malaysia
https://read.qxmd.com/read/38278316/dental-composite-biodeterioration-in-the-presence-of-oral-streptococci-and-extracellular-metabolic-products
#39
JOURNAL ARTICLE
Karabi Mondal, Karl J Rockne, James L Drummond, Evan P O'Brien, Chien-Chia Chen, Luke Hanley
OBJECTIVE: Secondary caries is a primary cause of early restoration failure. While primary dental caries has been extensively researched, our knowledge about the impact of secondary caries on dental restorations is relatively limited. In this study, we examined how different clinically relevant microbially-influenced environments impact the degradation of nano-filled (FIL) and micro-hybrid (AEL) dental composites. METHODS: Material strength of two commercial dental composites was measured following incubation in aqueous media containing: i) cariogenic (Streptococcus mutans) and non-cariogenic bacteria (Streptococcus sanguinis) grown on sucrose or glucose, ii) abiotic mixtures of artificial saliva and sucrose and glucose fermentation products (volatile fatty acids and ethanol) in proportions known to be produced by these microorganisms, and iii) abiotic mixtures of artificial saliva and esterase, a common oral extracellular enzyme...
January 24, 2024: Journal of Dentistry
https://read.qxmd.com/read/38277034/pomegranate-extract-in-polyphosphate-fluoride-mouthwash-reduces-enamel-demineralization
#40
JOURNAL ARTICLE
Ana Paula Miranda Vieira, Marcelle Danelon, Gabriela Lopes Fernandes, Andresa Aparecida Berretta, Andrei Felipe Moreira Buszinski, Lucinéia Dos Santos, Alberto Carlos Botazzo Delbem, Debora Barros Barbosa
OBJECTIVES: To evaluate the anti-demineralizing effect of a mouthwash comprising pomegranate peel extract (PPE 3%), sodium trimetaphosphate (TMP 0.3%), and fluoride (F 225 ppm) in an in situ study, and to assess its irritation potential in an ex vivo study. METHODS: This double-blind crossover study was conducted in four phases with 7 days each. Twelve volunteers used palatal appliances containing enamel blocks, which were subjected to cariogenic challenges...
January 26, 2024: Clinical Oral Investigations
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