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Bo Yang, Jun Liu, Zhiguo Liu, Yacheng Wang, Jiaming Cai, Lingjie Peng
Chitosan/Co-Fe-layered double hydroxides (CS/LDHs) were prepared by coprecipitation method, which is a kind of composite material with excellent properties. The structure of CS/LDHs was characterized by SEM, FTIR, and XRD, which proved that chitosan (CS) was successfully induced into hydrotalcite and CS/LDHs still possess the structural characteristics of hydrotalcite. The adsorption of 2,4-dichlorophenol (2,4-DCP) was studied with CS/LDHs and LDHs as adsorbent separately. The activity of immobilized laccase (L-CS/LDHs) with CS/LDHs as carrier is significantly better than that of the one (L-LDHs) using LDHs as carrier...
December 11, 2018: Environmental Science and Pollution Research International
Haiyun Ye, Ce Zheng, Xiaoping Lan, Limin Zhao, Tong Qiao, Xiaoyan Li, Yidan Zhang
PURPOSE: To evaluate the effect of adenoidectomy on the brains of children with obstructive sleep apnea-hypopnea syndrome (OSAS) through observation of the alteration of retinal perfusion by optical coherence tomography angiography (OCTA). METHODS: Sixty-two children with OSAS (124 eyes; 5.94 ± 1.64 years old; 53.2% boys) were enrolled in this study. Their retinal vascular network density indices, including vascular diameter (VD), vascular area density (VAD), vessel skeleton density (VSD), vessel perimeter index (VPI) on the macular superficial/deep capillary plexus (SCP/DCP), and the size of the foveal avascular zone (FAZ) were analyzed by OCTA before treatment and at 1 month after the adenoidectomy...
December 12, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Meng Tian, Christoph Tappeiner, Martin S Zinkernagel, Wolfgang Huf, Sebastian Wolf, Marion R Munk
PURPOSE: To evaluate vascular changes in patients with intermediate uveitis with or without retinal vasculitis using swept-source wide-field optical coherence tomography angiography (OCTA). METHODS: This is a prospective cross-sectional study. Consecutive patients with intermediate uveitis were evaluated using wide-field OCTA. Wide-field OCTA and en-face OCT images were analysed for the presence of capillary non-perfusion and reduced perfusion, disruption of ellipsoid zone, and abnormalities on en-face wide-field retinal thickness maps, respectively, and compared with fluorescein angiography (FA) findings in a subcohort...
December 11, 2018: British Journal of Ophthalmology
Isabel M A Brüggenwirth, Carolina Moore, Paria Mahboub, Max F Thijssen, Xiaofei E, Henri G D Leuvenink, Pranoti Mandrekar, Xiaofei Wang, Timothy F Kowalik, Robert J Porte, Paulo N Martins
Background: It remains controversial if arterial perfusion in addition to portal vein perfusion during machine preservation improves liver graft quality. Comparative studies using both techniques are lacking. We studied the impact of using single or dual machine perfusion of donation after circulatory death rat livers. In addition, we analyzed the effect of pulsatile versus continuous arterial flow. Methods: Donation after circulatory death rat livers (n = 18) were preserved by 6 hours cold storage, followed by 1 hour subnormothermic machine perfusion (20°C, pressure of 40/5 mm Hg) and 2 hours ex vivo warm reperfusion (37°C, pressure of 80/11 mm Hg, 9% whole blood)...
November 2018: Transplantation Direct
Jiankai Yang, Dongdong Gu, Kaijie Lin, Ying Yang, Chenglong Ma
The telson (tail plate) of Stomatopoda (mantis shrimp) shows excellent impact resistance properties, and its special structure is an ideal prototype to mimic. In this paper, a series of bi-directionally corrugated panel (DCP) structures inspired by the telson of mantis shrimp was designed. The crush simulation of DCP structures with different structural parameters, namely wavelength (λ) and amplitude (A), was carried out using ANSYS LS-DYNA. In order to verify the simulation results, AlSi10Mg components with DCP structures were fabricated by selective laser melting and the out-of-plane compression tests were conducted to investigate the compression performance...
November 27, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Hanjun Wu, Huali Zhang, Weijun Zhang, Xiaofang Yang, Hong Zhou, Zhiquan Pan, Dongsheng Wang
In this work, a novel core-shell structured magnetic polyimide@layered double oxides (LDO) composites coating a porous polyimide (PI)-coated Fe3 O4 magnetic core and layered double hydroxide (LDH) has been successfully synthesized by solve-thermal synthesis and co-precipitation process. The magnetic PI@LDO composites were characterized by scanning and transmission electron microscopy (SEM and TEM), X-ray diffraction (XRD), thermogravimetry analysis (TGA) and magnetic properties analysis. The composite materials displayed core-shell structure with flower-like morphology...
December 3, 2018: Chemosphere
M A Clara-Altamirano, D Y García-Ortega, A Maciel-Miranda, H Martínez-Said, J L Martínez-Tlahuel, C H S Caro-Sánchez, G C García-Ruíz, M Cuellar-Hubbe
Dedifferentiated parosteal osteosarcoma is a variant in which a high grade osteosarcoma coexists with a parosteal osteosarcoma. We report the case of a 20-year-old female patient who presented with six months of evolution of pain and functional limitation of the right forearm, with no apparent cause; radiographs were performed, observing a tumoral lesion in the diaphysis of the right ulna. Physical examination showed pain upon palpation in the diaphysis of the ulna and limitation of prone-supination. Axial computed tomography of the thorax revealed metastatic disease in the upper lobe of the left lung...
May 2018: Acta Ortopédica Mexicana
Laura E Heller, Paul David Roepe
We use Plasmodium falciparum culture synchronization, optimized heme and hemozoin extraction protocols, and mass spectrometry to quantify the abundance of free ferriprotoporphyrin IX (FPIX) heme and crystallized FPIX (hemozoin; Hz) for various growth stages of intraerythrocytic P. falciparum malarial parasites. Due to altered cell cycle kinetics for delayed clearance phenotype (DCP) parasites relative to control, we test whether FPIX and Hz abundances differ for DCP vs control parasites.
December 4, 2018: Biochemistry
Laura E Heller, Eibhlin Goggins, Paul David Roepe
Previously (Heller L. and Roepe, P.D.; preceeding paper, this issue) we quantified free ferriprotoporphyrin IX (FPIX) heme abundance for control vs delayed clearance phenotype (DCP) intraerythrocytic Plasmodium falciparum malarial parasites. Since artemisinin drugs are activated by free FPIX, these data predict that the abundance of long - hypothesized toxic artemisinin drug - FPIX covalent adducts might differ for control vs DCP parasites. If so, this would have important repercussions for understanding the mechanism of the DCP, also known as emerging artemisinin resistance...
December 4, 2018: Biochemistry
Su-Min Ha, Shin Hwang, Jin Young Park, Young-Joo Lee, Ki-Hun Kim, Gi-Won Song, Dong-Hwan Jung, Yun-Suk Yu, Jinpyo Kim, Kyoung-Jin Lee, Eunyoung Tak, Yo-Han Park, Sung-Gyu Lee
Purpose: OncoHepa test is a multigene expression profile test developed for assessment of hepatocellular carcinoma (HCC) prognosis. Multiplication of α-FP, des-γ-carboxy prothrombin (DCP) and tumor volume (TV) gives the α-FP-DCP-volume (ADV) score, which is also developed for assessment of HCC prognosis. Methods: The predictive powers of OncoHepa test and ADV score were validated in 35 patients who underwent curative hepatic resection for naïve solitary HCCs ≤5 cm...
December 2018: Annals of Surgical Treatment and Research
Bhumesh Kumar Katakam, S B Kavitha, G Narsimha Rao Netha, M Shahana, T Satya Sri, D Sudha Vani
Background: Pemphigus disorders are a group of immunobullous diseases affecting skin and/or mucus membranes. Dexamethasone cyclophosphamide pulse (DCP)/dexamethasone only pulse (DOP) therapy has shown promising results in the management of pemphigus group of diseases in adults. Aim: To evaluate the outcome of pulse therapy (PT) in pediatric cases diagnosed with pemphigus vulgaris (PV). Materials and Methods: Prospective study of 12 pediatric cases of PV from 2010 to 2015 and treated with PT in Gandhi Hospital...
November 2018: Indian Dermatology Online Journal
Ronilda Lacson, Eseosa Odigie, Aijia Wang, Neena Kapoor, Atul Shinagare, Giles Boland, Ramin Khorasani
RATIONALE AND OBJECTIVES: To quantify the use of Diagnostic Certainty Phrases (DCP) in radiology reports, including DCPs with good agreement (including "diagnostic of," "unlikely" and "represents") in connoting degree of certainty between providers based on previous studies; and to assess whether modality, presence of a trainee, radiologic subspecialty, and individual radiologists are associated with the usage of DCPs with good agreement. MATERIALS AND METHODS: This retrospective, IRB-approved study was conducted at an academic medical center...
November 28, 2018: Academic Radiology
Surendra Reddy Punganuru, Hanumantha Rao Madala, Viswanath Arutla, Kalkunte S Srivenugopal
Human NAD(P)H quinone oxidoreductase-1 (hNQO1) is an important cancer-related biomarker, which shows significant overexpression in malignant cells. Developing an effective method for detecting NQO1 activity with high sensitivity and selectivity in tumors holds a great potential for cancer diagnosis, treatment, and management. In the present study, we report a new dicyanoisophorone (DCP) based fluorescent probe (NQ-DCP) capable of monitoring hNQO1 activity in vitro and in vivo in both ratiometric and turn-on model...
November 28, 2018: Cancers
Shingo Shimada, Toshiya Kamiyama, Hideki Yokoo, Tatsuya Orimo, Akihisa Nagatsu, Takanori Ohata, Hirofumi Kamachi, Akinobu Taketomi
BACKGROUND: The aim was to evaluate the prognoses and clinicopathological characteristics of solitary hepatocellular carcinoma (HCC) originating from the caudate lobe (HCC-CL). METHODS: We analyzed 584 patients with a solitary tumor <10 cm from January 1990 to November 2014. Patients were classified into a caudate lobe group (CL; n = 39) and a non-caudate lobe group (NCL; n = 545). We investigated the prognoses and clinicopathological characteristics of solitary HCC-CL...
November 26, 2018: World Journal of Surgery
Seok-Young Oh, Yong-Deuk Seo
High-performance biochar synthesized via co-pyrolysis of a polymer and rice straw (RS) was evaluated as a sorbent for ionizable halogenated phenols. Compared with RS-derived biochar, the sorption of 2,4-dichlorophenol (DCP), 2,4-dibromophenol (DBP), and 2,4-difluorophenol (DFP) onto polymer/RS-derived biochar was significantly enhanced by the properties of biochar changing due to polymer residues. According to Langmuir sorption isotherm model maximum sorption capacities for DCP, DBP, and DFP were 25.5-27.8, 22...
November 22, 2018: Journal of Environmental Management
Hui Chen, Wei Chi, Xiaojuan Cai, Yang Deng, Xintong Jiang, Yantao Wei, Shaochong Zhang
PURPOSE: To evaluate pre-operative and post-operative morphologic characteristics in idiopathic macular epiretinal membrane (ERM) by optical coherence tomography angiography (OCTA). METHODS: Thirty-three subjects with unilateral idiopathic ERM were enrolled and the contralateral eyes served as controls. Vascular parameters including superficial capillary plexus (SCP), deep capillary plexus (DCP), outer capillary plexus (OCP), and choroidal capillary plexus (CCP) were evaluated by OCTA...
November 22, 2018: Eye
Yong Un Shin, Dong Eik Lee, Min Ho Kang, Mincheol Seong, Joo-Hark Yi, Sang-Woong Han, Heeyoon Cho
The purpose of this study is to evaluate the effect of haemodialysis on perfused vessel density, choroidal thickness (CT), and retinal thickness in end-stage renal disease (ESRD) using swept-source optical coherence tomography angiography (SS-OCTA). We studied twenty-nine eyes of 29 ESRD patients by ophthalmologic examination and SS-OCTA before and after haemodialysis. The colour-coded perfusion density maps were generated and perfused vessel density was calculated. Changes in systemic and other ocular parameters such as retinal and choroidal thickness were measured and analysed...
November 21, 2018: Scientific Reports
Christopher S Chung, Peter L Nesper, Justin J Park, Amani A Fawzi
BACKGROUND AND OBJECTIVES: Construct a method for visualizing the middle capillary plexus (MCP) using Zeiss optical coherence tomography angiography (OCTA) and compare to established segmentation methods using the Optovue system. PATIENTS AND METHODS: Twenty eyes with diabetic retinopathy were imaged. Visualization of the MCP, image artifacts, preservation of pathological changes, foveal avascular zone (FAZ) area, and vessel length density (VLD) were compared between devices...
November 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Justin J Park, Christopher S Chung, Amani A Fawzi
BACKGROUND AND OBJECTIVE: To assess the relationship between retinal vascular and structural changes in the superficial, middle, and deep capillary plexuses (SCP, MCP, DCP) using optical coherence tomography angiography (OCTA) and en face OCT. PATIENTS AND METHODS: Patients with diabetic retinopathy were imaged using the Cirrus HD-OCT with AngioPlex. Using manual segmentation of the retinal layers, the authors compared OCTA to en face OCT images to examine corresponding patterns in each of the three capillary plexuses...
November 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Shangjun Jiang, Netan Choudhry
BACKGROUND AND OBJECTIVE: To gain insight into clinical presentations associated with anomalous foveal avascular zone (FAZ) architecture and foveal pit morphology. PATIENTS AND METHODS: Twenty-two eyes with anomalous (vascularized) FAZs were identified from 14 patients using optical coherence tomography angiography (OCTA). The FAZ was evaluated in three vascular layers of the retina: the superficial capillary plexus (SCP), the deep capillary plexus (DCP), and the degree of foveal pit hypoplasia was graded...
November 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
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