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Diabetic maculopathy

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https://www.readbyqxmd.com/read/30308201/progression-of-diabetic-microaneurysms-according-to-the-internal-reflectivity-on-structural-oct-and-visibility-on-oct-angiography
#1
Mariacristina Parravano, Daniele De Geronimo, Fabio Scarinci, Gianni Virgili, Lea Querques, Monica Varano, Francesco Bandello, Giuseppe Querques
PURPOSE: To investigate the progression of diabetic microaneurysms (MAs) according to the SD-OCT and OCT Angiography (OCTA) characteristics and to evaluate their influence on the retinal extracellular fluid accumulation at 1 year follow-up in patients with non proliferative diabetic retinopathy (NPDR). DESIGN: Prospective, observational case series. METHODS: Fourteen patients with NPDR underwent SD-OCT and OCTA at the baseline and at 1 year follow-up...
October 8, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30284052/multilayered-deep-structure-tensor-delaunay-triangulation-and-morphing-based-automated-diagnosis-and-3d-presentation-of-human-macula
#2
Taimur Hassan, M Usman Akram, Mahmood Akhtar, Shoab Ahmad Khan, Ubaidullah Yasin
Maculopathy is the group of diseases that affects central vision of a person and they are often associated with diabetes. Many researchers reported automated diagnosis of maculopathy from optical coherence tomography (OCT) images. However, to the best of our knowledge there is no literature that presents a complete 3D suite for the extraction as well as diagnosis of macula. Therefore, this paper presents a multilayered convolutional neural networks (CNN) structure tensor Delaunay triangulation and morphing based fully autonomous system that extracts up to nine retinal and choroidal layers along with the macular fluids...
October 4, 2018: Journal of Medical Systems
https://www.readbyqxmd.com/read/30269098/united-kingdom-diabetic-retinopathy-electronic-medical-record-uk-dr-emr-users-group-report-4-real-world-data-on-the-impact-of-deprivation-on-the-presentation-of-diabetic-eye-disease-at-hospital-services
#3
Alastair K Denniston, Aaron Y Lee, Cecilia S Lee, David P Crabb, Clare Bailey, Peck-Lin Lip, Paul Taylor, Maria Pikoula, Esther Cook, Toks Akerele, Richard Antcliff, Christopher Brand, Usha Chakravarthy, Randhir Chavan, Narendra Dhingra, Louise Downey, Haralabos Eleftheriadis, Faruque Ghanchi, Rehna Khan, Vineeth Kumar, Aires Lobo, Andrew Lotery, Geeta Menon, Rajarshi Mukherjee, Helen Palmer, Sudeshna Patra, Bobby Paul, Dawn A Sim, James Stephen Talks, Elizabeth Wilkinson, Adnan Tufail, Catherine A Egan
AIM: To assess the impact of deprivation on diabetic retinopathy presentation and related treatment interventions, as observed within the UK hospital eye service. METHODS: This is a multicentre, national diabetic retinopathy database study with anonymised data extraction across 22 centres from an electronic medical record system. The following were the inclusion criteria: all patients with diabetes and a recorded, structured diabetic retinopathy grade. The minimum data set included, for baseline, age and Index of Multiple Deprivation, based on residential postcode; and for all time points, visual acuity, ETDRS grading of retinopathy and maculopathy, and interventions (laser, intravitreal therapies and surgery)...
September 29, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/30249823/cataract-surgery-in-diabetes-mellitus-a-systematic-review
#4
REVIEW
Aditya Kelkar, Jai Kelkar, Hetal Mehta, Winfried Amoaku
India is considered the diabetes capital of the world, and a significant proportion of patients undergoing cataract surgery are diabetic. Considering this, we reviewed the principles and guidelines of managing cataract in patients with diabetes. The preoperative, intraoperative, and postoperative factors are of paramount importance in the management of diabetic cataract patients. Particularly, the early recognition and treatment of diabetic retinopathy or maculopathy before cataract surgery influence the final visual outcome and play a major role in perioperative decision-making...
October 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/30221214/suspended-scattering-particles-in-motion-a-novel-feature-of-oct-angiography-in-exudative-maculopathies
#5
Amir H Kashani, Kyle M Green, Julie Kwon, Zhongdi Chu, Qinqin Zhang, Ruikang K Wang, Sean Garrity, David Sarraf, Carl B Rebhun, Nadia K Waheed, Karen B Schaal, Marion R Munk, Sarra Gattoussi, K Bailey Freund, Fang Zheng, Guanghui Liu, Philip J Rosenfeld
Objective: To characterize features of extra-vascular optical coherence tomography angiography (OCTA) signals corresponding to hyperreflective intraretinal fluid across various exudative maculopathies. Design: Multicenter, retrospective, observational study. Participants: Eyes with various forms of exudative maculopathy including diabetic retinopathy (DR), retinal vein occlusion (RVO), and neovascular-age related macular degeneration (nvAMD)...
July 2018: Ophthalmology Retina
https://www.readbyqxmd.com/read/30126649/paracentral-acute-middle-maculopathy-following-vitrectomy-for-proliferative-diabetic-retinopathy-incidence-risk-factors-and-clinical-characteristics
#6
Hiroshi Nakashima, Yasuaki Iwama, Kensuke Tanioka, Kazuyuki Emi
PURPOSE: To report the incidence of, risk factors for, and characteristics of paracentral acute middle maculopathy (PAMM) after 25-gauge pars plana vitrectomy for proliferative diabetic retinopathy (PDR). DESIGN: Retrospective, consecutive, interventional case series. PARTICIPANTS: Five hundred thirty eyes of 427 patients who underwent primary vitrectomy for PDR from 2013 through 2016. METHODS: The patients underwent measurement of best-corrected visual acuity (BCVA), fundus photography, and OCT before and within 2 weeks after vitrectomy...
August 17, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30121646/evaluation-of-vascular-changes-with-optical-coherence-tomography-angiography-after-plaque-radiotherapy-of-choroidal-melanoma
#7
Giovanni Cennamo, Maria Angelica Breve, Nunzio Velotti, Federica Sparnelli, Claudio Iovino, Antonio Farella, Raffaele Liuzzi, Giuseppe de Crecchio, Gilda Cennamo
AIM: The purpose of this paper was to evaluate whether optical coherence tomography angiography (OCT-A) can be used to quantify the vascular changes in radiation maculopathy, and changes in the tumor vasculature in eyes treated with plaque radiotherapy for choroidal melanoma. METHODS: In this prospective study, we evaluated 39 Caucasian patients with choroidal melanoma (39 eyes) treated with ruthenium-106 plaque radiotherapy. The patients underwent complete ophthalmic examination, bulbar echography, and OCT-A before and 1 year after treatment...
August 17, 2018: Ophthalmic Research
https://www.readbyqxmd.com/read/29975344/phacoemulsification-cataract-surgery-with-prophylactic-intravitreal-bevacizumab-for-patients-with-coexisting-diabetic-retinopathy-a-meta-analysis
#8
Yifan Feng, Senmiao Zhu, Eirini Skiadaresi, Colm McAlinden, Ruixue Tu, Rongrong Gao, Jeffrey W Stephens, Qinmei Wang, Jinhai Huang
PURPOSE: To evaluate the clinical effectiveness of intravitreal bevacizumab (IVB) injection combined with cataract surgery in the treatment of patients with cataract and coexisting diabetic retinopathy (DR). METHODS: Pertinent comparative studies were identified through systemic searches of PubMed, EMBASE, and the Cochrane Controlled Trials Register up to March 1, 2016. Outcome measures included corrected distance vision acuity, central macular thickness, and progression of DR and maculopathy...
June 28, 2018: Retina
https://www.readbyqxmd.com/read/29973367/rapid-assessment-of-avoidable-blindness-and-diabetic-retinopathy-in-people-aged-50-years-and-older-in-the-national-capital-district-of-papua-new-guinea
#9
Anthea Burnett, Ling Lee, Fabrizio D'Esposito, Geoffrey Wabulembo, Anaseini Cama, Georgia Guldan, Marleen Nelisse, Samuel Peter Koim, Drew Keys, Alison J Poffley, Hans Limburg, Jambi Garap
BACKGROUND/AIMS: To conduct an assessment of avoidable blindness, diabetes mellitus and diabetic retinopathy (DR) in adults aged 50 years and older in the National Capital District (NCD) region of Papua New Guinea (PNG). METHODS: A cross-sectional population-based survey was performed for which 25 clusters of 50 people aged ≥50 years were randomly selected from the NCD region. The standardised rapid assessment of avoidable blindness (RAAB) with diabetic retinopathy (+DR) methodology was used...
July 4, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29858676/subjective-evaluation-of-visual-acuity-is-not-reliable-to-detect-disease-activity-in-different-exudative-maculopathies
#10
Marie-Christine Bruender, Nicola Benjamin, Hansjuergen Thomas Agostini, Andreas Stahl, Christoph Ehlken
BACKGROUND: Patients with exudative maculopathies (neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO)) are faced with a high burden of examinations and treatments. This study was conceived to analyze the accuracy of a subjective evaluation of visual acuity (VA) and metamorphopsia to detect disease reactivation, compared to morphological signs of reactivation assessed by means of SD-OCT. METHODS: Retrospective study of 888 patients treated for nAMD (n = 638), DME (84), BRVO (110), and CRVO (56) was conducted...
September 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29784154/assessing-patient-acceptance-of-virtual-clinics-for-diabetic-retinopathy-a-large-scale-postal-survey
#11
Dana Ahnood, Ahmad Souriti, Gwyn Samuel Williams
OBJECTIVE: To explore the views of patients with diabetic retinopathy and maculopathy on their acceptance of virtual clinic review in place of face-to-face clinic appointments. METHODS: A postal survey was mailed to all 813 patients under the care of the diabetic eye clinic at Singleton Hospital with 7 questions, explanatory information, and a stamped, addressed envelope available for returning completed questionnaires. RESULTS: Four hundred and ninety-eight questionnaires were returned indicating that 86...
June 2018: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29687595/the-area-of-fixation-covaries-with-short-term-changes-in-visual-acuity-after-anti-vascular-endothelial-growth-factor-treatment-in-patients-with-diabetic-macular-oedema
#12
Nanna Staehr Jakobsen, Dorte Ancher Larsen, Toke Bek
PURPOSE: Diabetic maculopathy can be treated with intravitreal injection of vascular endothelial growth factor (VEGF) inhibitors. However, the therapy is not effective in all patients, and it would be desirable to have parameters for differentiating patients who will benefit from treatment from those who will not. Retinal fixation has been shown to be impaired in patients with low visual acuity (VA) secondary to macular disease, but the changes in fixational eye movements after anti-VEGF treatment for diabetic maculopathy have not been investigated...
April 24, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29643776/patch-grafting-using-an-ologen-collagen-matrix-to-manage-tubal-exposure-in-glaucoma-tube-shunt-surgery
#13
Masaki Tanito, Ichiya Sano, Yoshifumi Ikeda, Etsuko Fujihara
Purpose: To report the results using an ologen Collagen Matrix as a patch graft in eyes with tubal exposure after tube shunt surgery. Case Reports: Case 1 was an 82-year-old man with tubal exposure in his right eye 26 months after receiving a Baerveldt glaucoma implant. The tube was covered by surrounding conjunctival tissue combined with subconjunctival placement of an ologen Collagen Matrix as a patch graft. Two years after implantation, the tube was not exposed...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29614075/association-between-the-retinal-vascular-network-with-singapore-i-vessel-assessment-siva-software-cardiovascular-history-and-risk-factors-in-the-elderly-the-montrachet-study-population-based-study
#14
Louis Arnould, Christine Binquet, Charles Guenancia, Seydou Alassane, Ryo Kawasaki, Vincent Daien, Christophe Tzourio, Yumiko Kawasaki, Abderrahmane Bourredjem, Alain Bron, Catherine Creuzot-Garcher
PURPOSE: To identify patterns summarizing the retinal vascular network in the elderly and to investigate the relationship of these vascular patterns with cardiovascular history. METHODS: We conducted a population-based study, the Montrachet study (Maculopathy Optic Nerve nuTRition neurovAsCular and HEarT diseases), in participants older than 75 years. The history of cardiovascular disease and a score-based estimation of their 10-year risk of cardiovascular mortality (Heart SCORE) were collected...
2018: PloS One
https://www.readbyqxmd.com/read/29554812/clinical-applications-of-optical-coherence-tomography-angiography-what-we-have-learnt-in-the-first-3-years
#15
Salomon Y Cohen, Alexandra Miere, Sylvia Nghiem-Buffet, Franck Fajnkuchen, Eric H Souied, Sarah Mrejen
A review of the literature from 2014 to 2016 was conducted, focusing on the results of optical coherence tomography angiography in different chorioretinal diseases. In only 3 years, optical coherence tomography angiography has been shown to be an effective tool for diagnosing choroidal neovascularization complicating age-related macular degeneration, pathologic myopia, and inflammatory conditions. The technique has sometimes been considered superior to conventional multimodal imaging, for example, in choroidal neovascularization associated with chronic central serous chorioretinopathy or multifocal choroiditis...
March 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29550187/effects-of-crocin-on-diabetic-maculopathy-a-placebo-controlled-randomized-clinical-trial
#16
Samaneh Sepahi, Seyed Ahmad Mohajeri, Seyedeh Maryam Hosseini, Elham Khodaverdi, Nasser Shoeibi, Maral Namdari, Sayyed Abolghasem Sajadi Tabassi
OBJECTIVE: Diabetic macular edema (DME) is one of the most important sight-threatening complications in patients with diabetes. Owing to neuroprotective properties, crocin, as the main constituent in saffron, is thought to be useful in the treatment and prevention of diabetic maculopathy. The aim of this trial was to evaluate the effects of crocin as a supplement on reducing inflammation in patients with diabetic maculopathy. DESIGN: Double-masked, placebo controlled, phase 2 randomized clinical trial...
June 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29533284/posterior-fundus-hemorrhages-frequency-and-associated-factors-the-beijing-eye-study
#17
Jin Qiong Zhou, Ya Xing Wang, Liang Xu, Liang Zhao, Shuang Wang, Jie Xu, Qi Sheng You, Hua Yang, Wen Bin Wei, Jost B Jonas
PURPOSE: To examine frequency and associations of retinal hemorrhages. METHODS: The population-based Beijing Eye Study included 3,468 individuals. Monoscopic fundus photographs were examined for hemorrhages. RESULTS: Retinal hemorrhages were detected in 515 eyes (429 individuals) (prevalence: 7.6%; 95% confidence interval [CI]: 7.0-8.0 per eye; 12.7%; 95% CI: 11.7-13.7 per person). Higher prevalence of retinal hemorrhages was correlated (multivariate analysis) with higher systolic blood pressure (P < 0...
March 12, 2018: Retina
https://www.readbyqxmd.com/read/29492053/fundus-fluorescence-angiography-in-diagnosing-diabetic-retinopathy
#18
Shuhui Wang, Yuqin Zuo, Ning Wang, Bin Tong
Objective: To investigate the manifestation characteristics of fundus fluorescence angiography (FFA) and its values in diagnosing diabetic retinopathy through comparing direct ophthalmoscopy. Methods: Two hundred fifty patients (500 eyes) who were suspected as diabetic retinopathy and admitted to the hospital between February 2015 and December 2016 were selected. They underwent direct ophthalmoscopy and FFA. The manifestation characteristics of FFA in the diagnosis of diabetic retinopathy were summarized...
November 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29480273/transient-reversal-of-macular-ischemia-with-intravitreal-steroid-implant-injection-in-a-case-of-radiation-maculopathy
#19
Aditya Verma, Vikas Khetan
Diabetic retinopathy (DR) is a well-known risk factor in the development of radiation maculopathy (RM). Steroids have been shown to improve the vision and reduce the macular thickness in patients with RM. This observational case report highlights altered course of DR after a course of radiotherapy for orbital lymphoma, after a single dose of intravitreal dexamethasone implant showed a dramatic revascularization of the ischemic macula, with a significant reduction in the size of ischemic area. This appears to be the first case in literature corroborating the favorable effect on steroids on retinal vasculature, seen angiographically...
March 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29392642/impairment-of-acquired-color-vision-in-multiple-sclerosis-an-early-diagnostic-sign-linked-to-the-greatness-of-disease
#20
Anna Piro, Antonio Tagarelli, Giuseppe Nicoletti, Sara Scannapieco, Serena Polidoro, Paola Valentino, Aldo Quattrone
OBJECTIVE: To assess the type and degree of both red-green and blue-yellow color vision deficiencies of Calabrian males affected by multiple sclerosis. MATERIAL: Eighty Calabrian male patients were enrolled (age range 18-70 years; mean age 40.6 ± 12.4 years) showing a disease duration mean of 10.6 ± 8.2 years (range = 0.5-46 years) coming from the Institute of Neurology, Magna Graecia University, Catanzaro. Optic neuritis present in the medical histories of the 21 patients does not influence color vision...
February 1, 2018: International Ophthalmology
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