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https://www.readbyqxmd.com/read/30107547/maternal-nutrient-restriction-alters-uterine-artery-hemodynamics-and-placentome-vascular-density-in-bos-indicus-and-bos-taurus
#1
Caleb O Lemley, Caitlin G Hart, Racheal L Lemire, E Heath King, Richard M Hopper, Seong B Park, Brian J Rude, Derris D Burnett
The objective was to examine uterine artery blood flow (UBF) as well as macroscopic and microscopic placentome vascular density in nutrient restricted Angus and Brahman heifers. Angus (n = 6) and Brahman (n = 6) heifers were bred to a single sire and pregnancy confirmed at 30 days post-breeding. Heifers were randomly assigned to one of two dietary treatments consisting of 100% (control fed; CON; n = 6) or 60% (total nutrient restricted; RES; n = 6) based from net energy requirements for gestating heifers. Nutritional treatments were imposed from day 50 to 180 of gestation...
August 13, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/30101329/sleep-nutrition-and-physical-activity-interventions-to-prevent-obesity-in-infancy-follow-up-of-the-prevention-of-overweight-in-infancy-poi-randomized-controlled-trial-at-ages-3-5-and-5-y
#2
Rachael W Taylor, Andrew R Gray, Anne-Louise M Heath, Barbara C Galland, Julie Lawrence, Rachel Sayers, Dione Healey, Gerald W Tannock, Kim A Meredith-Jones, Maha Hanna, Burt Hatch, Barry J Taylor
Background: Our Prevention of Overweight in Infancy (POI) study suggested that a brief sleep intervention in infancy reduced the risk of obesity at age 2 y. In contrast, we observed no benefit from the nutrition and activity intervention. Objective: The objective of the study was to determine how these interventions influenced growth at ages 3.5 and 5 y compared with usual care (Control). Design: A follow-up of a parallel, 4-arm, single-blind, 2-y, randomized controlled trial in 802 women (86% European, 48% primiparous) recruited in pregnancy (58% response rate) was undertaken...
August 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/30096890/comorbidity-of-physical-and-anxiety-symptoms-in-adolescent-functional-impairment-self-rated-health-and-subjective-well-being
#3
Judit Balázs, Mónika Miklósi, Agnes Keresztény, Christina W Hoven, Vladimir Carli, Camilla Wasserman, Gergö Hadlaczky, Alan Apter, Julio Bobes, Romuald Brunner, Paul Corcoran, Doina Cosman, Christian Haring, Jean-Pierre Kahn, Vita Postuvan, Michael Kaess, Airi Varnik, Marco Sarchiapone, Danuta Wasserman
Physical disorders and anxiety are frequently comorbid. This study investigates the characteristics of physical disorders, self-rated heath, subjective well-being and anxiety in adolescents. Data were drawn from the Saving and Empowering Young Lives in Europe cohort study. From 11 countries 11,230 adolescents, aged 14⁻16 years were included. Zung Self-Rating Anxiety Scale (SAS), WHO-5 Well-Being Index and five questions prepared for this study to evaluate physical illnesses and self-rated heath were administered...
August 9, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/30091235/a-contemporary-review-of-severe-aortic-stenosis
#4
REVIEW
Heath Sl Adams, Srikkumar Ashokkumar, Andrew Newcomb, Andrew I MacIsaac, Robert J Whitbourn, Sonny Palmer
Severe aortic stenosis (AS) is the most common form of valvular heart disease in the developed world with a rising prevalence due to an ageing Australian population. Transcatheter aortic valve implantation (TAVI) offers a less invasive option for the treatment of severe AS with evidence supporting of TAVI compared to medical therapy in inoperable patients, and superior to surgical aortic valve replacement (SAVR) in high-risk patients. Equal outcomes have been observed in all-comer intermediate risk populations...
August 8, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/30089601/case-control-study-of-pd-1-pd-l1-and-b7-h3-expression-in-lung-cancer-patients-with-and-without-human-immunodeficiency-virus-hiv-infection
#5
Katherine A Scilla, Dan P Zandberg, Søren M Bentzen, Candace Mainor, Jonathon Heath, Olga B Ioffe, Ashley L Cellini, Martin J Edelman, David J Riedel, Josephine L Feliciano
OBJECTIVE: Co-signaling molecules PD-L1, B7-H3, and PD-1 play a key role in cancer immunology. There are limited but emerging data on expression of these molecules in HIV-infected lung cancer patients. MATERIALS AND METHODS: We reviewed archived lung cancer tissue samples from HIV-infected cases (n = 13) and HIV-uninfected controls (n = 13) from 2001-2015. Cases and controls were matched by histology and stage. Immunostained tumor sections were analyzed for percent of tumor cells expressing PD-L1 and B7-H3, and percent of tumor infiltrating immune cells (TII) expressing PD-1 and PD-L1...
September 2018: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/30082339/cancer-patients-organisation-participation-in-heath-policy-decision-making-a-snapshot-cluster-analysis-of-the-eu-28-countries
#6
Kyriakos Souliotis, Lily-Evangelia Peppou, Chara Tzavara, Eirini Agapidaki, Dimitrios Varvaras, Oreste Buonomo, Dominique Debiais, Stanimir Hasurdjiev, Francois Sarkozy
OBJECTIVES: Even though patient involvement in health policy decision-making is well documented, studies evaluating the degree and impact of this participation are scarce. This is even more conspicuous in the case of cancer. There is evidence showing that patients with the same type of cancer and at the same stage of the disease will receive different treatments in different countries. Therefore, it is crucial to assess the degree of patient participation in health policy decision-making across Europe, as it may result in health inequalities across countries...
August 5, 2018: BMJ Open
https://www.readbyqxmd.com/read/30039209/alcohol-contributes-to-attraction-of-heliothis-chloridea-virescens-males-to-females
#7
Astrid T Groot, Satoshi Nojima, Jeremy J Heath, Byrappa Ammagarahalli, Michiel van Wijk, Alice Claβen, Richard G Santangelo, Juan Lopez, Coby Schal
Female-emitted volatile sex pheromones in most moths are composed of biosynthetically related blends of fatty acid derivatives, such as aldehydes, acetate esters and alcohols. In many moths, as in the noctuid Heliothis (Chloridea) virescens, the pheromone gland contains alcohols (e.g., (Z)-11-hexadecen-1-ol, hereafter Z11-16:OH) that may serve dual functions as pheromone components as well as precursors of other pheromone components. The relative importance of Z11-16:OH to male attraction in H. virescens has been controversial...
August 2018: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/30032216/cognitive-decline-and-alcohol-consumption-adjusting-for-functional-status-over-a-3-year-period-in-french-speaking-community-living-older-adults
#8
Helen-Maria Vasiliadis, Marie-Christine Payette, Djamal Berbiche, Sébastien Grenier, Carol Hudon
Background: The effect of alcohol consumption on cognitive decline is not clear. We aimed to study the association between alcohol consumption and cognitive functioning controlling for functional heath status. Methods: A total of 1610 older adults with a score ≥26 on the Mini-Mental State Examination (MMSE) were followed to assess the change in scores at the 3-year follow-up. Information on alcohol consumption as well as socio-demographic, lifestyle, psychosocial and clinical factors, as well as health service use were assessed at baseline and 3-year follow-up interviews...
July 19, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/30022306/disease-outbreak-accompanies-the-dispersive-structure-of-shrimp-gut-bacterial-community-with-a-simple-core-microbiota
#9
Zhiyuan Yao, Kunjie Yang, Lei Huang, Xiaolin Huang, Linglin Qiuqian, Kai Wang, Demin Zhang
Increasing evidence has emerged supporting a tight link between gut bacterial community and shrimp health. However, the knowledge about the variation of gut bacterial community, especially with different disease onset time, remains elusive. Here, healthy and diseased shrimps were collected at 3 disease-outbreak times (day 70, 80 and 85) to investigate the variation of gut bacterial community and its underlying ecological process with 16S rRNA gene amplicon sequencing. The gut bacterial community of diseased shrimp was distinct from the healthy one and temporally less stable, characterized by decreased alpha-diversity and dispersive structure...
July 18, 2018: AMB Express
https://www.readbyqxmd.com/read/29996921/salvage-pembrolizumab-added-to-kinase-inhibitor-therapy-for-the-treatment-of-anaplastic-thyroid-carcinoma
#10
Priyanka C Iyer, Ramona Dadu, Maria Gule-Monroe, Naifa L Busaidy, Renata Ferrarotto, Mouhammed Amir Habra, Mark Zafereo, Michelle D Williams, G Brandon Gunn, Horiana Grosu, Heath D Skinner, Erich M Sturgis, Neil Gross, Maria E Cabanillas
BACKGROUND: Anaplastic thyroid carcinoma (ATC) is a rare but deadly form of thyroid cancer. Kinase inhibitors kinase inhibitors have shown clinical efficacy in the management of ATC, however, eventually these tumors acquire resistance to KI and patients succumb to their disease. Salvage therapy in this setting is limited. As ATC tumors diffusely express the programmed cell death protein ligand (PD-L1), anti- programmed cell death protein (PD-1) drugs such as pembrolizumab offer therapeutic potential...
July 11, 2018: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/29979578/allosteric-inhibitor-of-kras-identified-using-a-barcoded-assay-microchip-platform
#11
Amy M McCarthy, Jungwoo Kim, A Katrine Museth, Ryan K Henning, John E Heath, Emma Winson, Joseph J Oh, Jingxin Liang, Sunga Hong, James R Heath
Protein catalyzed capture agents (PCCs) are synthetic antibody surrogates that can target a wide variety of biologically relevant proteins. As a step toward developing a high-throughput PCC pipeline, we report on the preparation of a barcoded rapid assay platform for the analysis of hits from PCC library screens. The platform is constructed by first surface patterning a micrometer scale barcode composed of orthogonal ssDNA strands onto a glass slide. The slide is then partitioned into microwells, each of which contains multiple copies of the full barcode...
July 19, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29960060/significance-of-negative-post-treatment-18-fdg-pet-ct-imaging-in-patients-with-p16-hpv-positive-oropharyngeal-cancer
#12
Sweet Ping Ng, Jason M Johnson, G Brandon Gunn, David I Rosenthal, Heath D Skinner, Jack Phan, Steven J Frank, William Morrison, Erich M Sturgis, Frank E Mott, Michelle D Williams, Clifton D Fuller, Adam S Garden
INTRODUCTION: Patients with p16/HPV-associated oropharyngeal squamous cell carcinoma have a favorable outcome after treatment. In this group of patients who potentially have a long life expectancy, the optimal surveillance strategy and modality is not well established. We aim to determine the ability of a negative post-radiation PET/CT scan in predicting the risk of subsequent relapse in these patients. MATERIALS/METHODS: A retrospective analysis of patients with p16/HPV-associated oropharyngeal squamous cell carcinoma who completed definitive (chemo)radiotherapy and had a post-treatment PET/CT scan from 2006 to 2013 was performed...
June 27, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29950456/impact-of-a-modified-version-of-baby-led-weaning-on-iron-intake-and-status-a-randomised-controlled-trial
#13
Lisa Daniels, Rachael W Taylor, Sheila M Williams, Rosalind S Gibson, Elizabeth A Fleming, Benjamin J Wheeler, Barry J Taylor, Jillian J Haszard, Anne-Louise M Heath
OBJECTIVE: To determine the iron intake and status of infants following a version of baby-led weaning (BLW) modified to prevent iron deficiency (Baby-Led Introduction to SolidS; BLISS) compared with those of infants following traditional spoon-feeding. DESIGN, PARTICIPANTS AND INTERVENTION: This randomised controlled trial included 206 participants assigned to control (n=101) or BLISS (n=105) groups. Both groups received standard midwifery and 'Well Child' care...
June 27, 2018: BMJ Open
https://www.readbyqxmd.com/read/29929388/mental-health-in-the-cree-peoples-of-northern-quebec-relationships-among-trauma-familial-psychological-distress-and-mood-or-anxiety-disorders
#14
Laura M Heath, Jill Torrie, Kathryn J Gill
OBJECTIVE: This study examined the physical and mental health of Cree adults, as well as the personal, clinical, and environmental factors associated with the presence of lifetime anxiety and mood disorders. METHODS: Mental health was assessed using the computerised version of the Diagnostic Interview Schedule (CDIS-IV), and standardised instruments were used to assess physical health, addiction severity, and psychological distress in 506 randomly selected participants from 4 Northern Cree communities in Quebec...
January 1, 2018: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/29926521/health-related-quality-of-life-and-health-utility-of-chinese-patients-undergoing-nocturnal-home-haemodialysis-in-comparison-to-other-modes-of-dialysis
#15
Carlos K H Wong, Julie Y Chen, Samuel K S Fung, Wai Kei Lo, Sing Leung Lui, Daniel T M Chan, Yuk Lun Cheng, Irene Kong, Eric Y F Wan, Cindy L K Lam
BACKGROUND: To compare the health-related quality of life (HRQOL) and health utility of Chinese patients with end-stage renal disease (ESRD) undergoing nocturnal home haemodialysis against those patients undergoing other modes of dialysis. METHODS: Chinese ESRD patients undergoing nocturnal home haemodialysis were recruited in renal specialist outpatient clinics at three public hospitals in Hong Kong. SF-12 Health Survey (SF-12) was used to measure HRQOL and generate the SF-6D heath utility score...
June 21, 2018: Nephrology
https://www.readbyqxmd.com/read/29922310/invasion-of-a-legume-ecosystem-engineer-in-a-cold-biome-alters-plant-biodiversity
#16
Vanessa M S Vetter, Nils B Tjaden, Anja Jaeschke, Constanze Buhk, Veronika Wahl, Pawel Wasowicz, Anke Jentsch
Plant ecosystem engineers are widely used to combat land degradation. However, the ability of those plants to modulate limiting abiotic and biotic resources of other species can cause damage to ecosystems in which they become invasive. Here, we use Lupinus nootkatensis as example to estimate and project the hazardous potential of nitrogen fixing herbaceous plants in a sub-polar oceanic climate. L. nootkatensis was introduced to Iceland in the 1940s to address erosion problems and foster reforestation, but subsequently became a high-latitude invader...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29914859/young-people-s-experiences-of-viewing-the-fitspiration-social-media-trend-qualitative-study
#17
Stephanie Easton, Katherine Morton, Zara Tappy, Daniella Francis, Laura Dennison
BACKGROUND: Social media use has become ubiquitous in the lives of many people, especially young adults. A popular recent trend emerging on social media is that of posting and following 'Fitspirational' content - material that purports to motivate and showcase healthy lifestyle habits, particularly relating to exercise and diet. There is very limited existing literature on how engaging with this type of content influences people's psychological and physical heath. Initial studies have focused on concerns over potential negative effects on psychological wellbeing including body image, self-esteem and eating disorders...
June 18, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29889618/supramaximal-eccentrics-versus-traditional-loading-in-improving-lower-body-1rm-a-meta-analysis
#18
Andrew N L Buskard, Heath R Gregg, Soyeon Ahn
Guidelines for improving maximal concentric strength through resistance training (RT) have traditionally included large muscle-group exercises, full ranges of motion, and a load approximating 85% of the 1-repetition maximum (1RM). Supramaximal eccentric training (SME; controlled lowering of loads above the concentric 1RM) has also been shown to be effective at increasing concentric 1RM in the lower body, but concerns regarding injury risk, postexercise soreness, and null benefit over traditional methods (TRAD) may limit the practical utility of this approach...
June 11, 2018: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/29886805/psychosocial-and-biological-paternal-role-in-pregnancy-outcomes
#19
Maryam Kashanian, Masoomeh Faghankhani, Hasti Hadizadeh, M Masoud Salehi, Masoomeh Yousefzadeh Roshan, Mohammad Ehsani Pour, Ladan Sayyah Ensan, Narges Sheikhansari
BACKGROUND: Pregnancy outcomes are affected by many different factors. One of the influential factors on pregnancy outcomes is the male partner as an important person to mother's wellbeing. OBJECTIVE: The aim of the present study was to investigate the effects of male partner's role including socioeconomic support, emotional support, accompanying pregnant women during prenatal care visits (PNC) and labor, and the level of pregnant women's satisfaction from their partners' support and involvement during pregnancy on pregnancy outcomes...
July 22, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29880769/impact-of-a-modified-version-of-baby-led-weaning-on-infant-food-and-nutrient-intakes-the-bliss-randomized-controlled-trial
#20
Liz Williams Erickson, Rachael W Taylor, Jillian J Haszard, Elizabeth A Fleming, Lisa Daniels, Brittany J Morison, Claudia Leong, Louise J Fangupo, Benjamin J Wheeler, Barry J Taylor, Lisa Te Morenga, Rachael M McLean, Anne-Louise M Heath
Despite growing international interest in Baby-Led Weaning (BLW), we know almost nothing about food and nutrient intake in infants following baby-led approaches to infant feeding. The aim of this paper was to determine the impact of modified BLW (i.e., Baby-Led Introduction to SolidS; BLISS) on food and nutrient intake at 7⁻24 months of age. Two hundred and six women recruited in late pregnancy were randomized to Control ( n = 101) or BLISS ( n = 105) groups. All participants received standard well-child care...
June 7, 2018: Nutrients
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