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Surgery Hepatic

Q X Wang, X Ma
IgG4-associated hepatobiliary diseases are group of autoimmune diseases characterized by lymphoplasmacytic infiltrates with an elevated serum IgG4 levels, affecting pancreas and biliary tract. In addition, it mainly includes IgG4-related sclerosing cholangitis, IgG4-related autoimmune pancreatitis and IgG4-related autoimmune hepatitis. An accurate diagnosis helps to avoid unnecessary surgery. Notably, an early diagnosis and treatment can improve the prognosis and enhance the quality of life. This review will focus on research advances and difficulties encountered in the study of IgG4 related hepatobiliary diseases...
June 20, 2018: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
Simone Garzon, Ricciarda Raffaelli, Umberto Montin, Fabio Ghezzi
OBJECTIVE: To report a case of primary hepatic pregnancy complicated by acute hemoperitoneum that was treated with a laparoscopic approach. DESIGN: Case report and review of the literature. SETTING: Obstetrics and gynecology unit of a university hospital. PATIENT(S): A 37-year-old pregnant woman who presented with vaginal bleeding. INTERVENTION(S): Diagnosis by abdominal ultrasound and computed tomography...
October 2018: Fertility and Sterility
Celiac trunk is the artery of foregut, arising from the abdominal aorta at the level of T12/L1 vertebral body. It extends approximately 1.5 to 2 cm horizontally forwards before dividing into three branches: left gastric, common hepatic, and splenic arteries. Out of the three ventral branches of abdominal aorta, celiac trunk is more prone to have variations. During routine dissection of abdomen for undergraduate students we found some rare variations in the branching pattern of the celiac trunk. Absence of celiac trunk with hepatomesenteric trunk, quadrifurcation with dorsal pancreatic artery arising from it, quadrifurcation with middle colic artery arising from it, left inferior phrenic artery arising from celiac trunk, highly tortuous splenic artery supplying distal 1/3rd of transverse colon and hepatosplenic trunk...
September 2018: Anatomy & Cell Biology
Lena Sibulesky, Scott W Biggins, Raimund Pichler
Acute kidney injury (AKI) is a frequent postoperative complication after liver transplantation. The etiology is multifactorial, including perioperative renal status, surgery related events, and postoperative immunosuppression therapy. The role of renal hypoperfusion and hepatic ischemia-reperfusion injury as causes of early AKI are now being increasingly recognized. Further studies should focus on therapies that would attenuate this injury.
September 27, 2018: World Journal of Hepatology
S Rabiou, M Lakranbi, Y Ouadnouni, D Benajah, M Smahi
INTRODUCTION: The biliobronchial fistula of hydatic origin is a rare complication and the left localization is exceptional. OBSERVATION: We report the case of a 26-year-old patient from the rural area who was referred to us for treatment of biliptysis. The thoracic and abdominal computed tomography diagnosed a left biliobronchial fistula was. Management consisted of primary endoscopic sphincterotomy, followed by left exclusive thoracotomy surgery to treat pulmonary, hepatic and diaphragmatic repair...
October 8, 2018: Revue de Pneumologie Clinique
Fei Liu, Jun-Ke Wang, Wen-Jie Ma, Qin Yang, Hai-Jie Hu, Fu-Yu Li
BACKGROUND: This study evaluated the predictive ability of preoperative carbohydrate antigen 19-9 (CA19-9) level in assessing tumour resectability in patients with gallbladder carcinoma (GBC). METHODS: We retrospectively analysed preoperative serum levels of CA19-9 in 292 patients with potentially resectable GBC between January 2000 and March 2016 in our institution. All final diagnoses were confirmed by pathological examination. The optimal cut-off point of the CA19-9 for predicting resectability was determined by the receiver operating characteristic curve...
October 10, 2018: ANZ Journal of Surgery
Samet Yardımcı, İlter Özer, Tahsin Dalgıç, Nesrin Turhan, Erdal Birol Bostancı
Malignant insulinomas are infrequent endocrine tumors with miscellaneous clinical courses. In this report, we present a rare case of insulinoma that recurred with solitary hepatic metastasis 15 years after the initial resection of the primary tumor from the pancreas. A 20-year-old woman first presented with the symptoms of hypoglycemia in 1996. The diagnosis of pancreatic insulinoma was confirmed by laboratory findings, and the initial surgery had been performed involving complete enucleation of the pancreatic mass...
2018: Turkish Journal of Surgery
William Beaubien-Souligny, Marie-Noëlle Pépin, Louis Legault, Jean-François Cailhier, Jean Éthier, Louis Bouchard, Bernard Willems, André Y Denault
Rationale: Acute kidney injury (AKI) is a frequent complication after liver transplantation. In some patients, prompt intervention targeted at a specific etiology is of paramount importance. Presenting concerns of the patients: A 25 years old man with advanced liver cirrhosis caused by sclerosing cholangitis and autoimmune hepatitis underwent orthotopic liver transplantation. One month after surgery, severe AKI developed in conjunction with recurrent ascites and lower extremity edema...
2018: Canadian Journal of Kidney Health and Disease
Volkan Öter, İlter Özer, Tahsin Dalgıç, Cemil Binarbaşı, Murat Ulaş, Erdal Birol Bostancı
BACKGROUND/AIMS: Hilar cholangiocarcinoma (HC) is a tumor that invades the confluence of the left and right hepatic bile ducts. Surgery is the definitive treatment but is also technically demanding. Here, we report our experience on 42 patients who underwent surgical resection for HC. The aim of the present study was to evaluate the margin status of resected specimens on frozen sections and the impact of R1 resection margin on survival. MATERIALS AND METHODS: A total of 42 patients with HC who underwent surgical resection in our clinic between January 2008 and January 2017 were included in the study...
October 9, 2018: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
M Gabrielle Pagé, Paul J Karanicolas, Sean Cleary, Alice C Wei, Paul McHardy, Salima S J Ladak, Nour Ayach, Jason Sawyer, Stuart A McCluskey, Coimbatore Srinivas, Joel Katz, Natalie Coburn, Julie Hallet, Calvin Law, Paul Greig, Hance Clarke
BACKGROUND: The study aims were to model acute pain intensity and opioid consumption trajectories up to 72 hours after open hepatic resection, identify predictors of trajectory membership and examine the association between trajectory memberships and six-month pain and psychological outcomes. This is a long-term analysis of a published randomized controlled trial on the impact of medial open transversus abdominis plane catheters on post-operative outcomes. METHODS: A total of 152 patients (89 males; mean age 63...
October 9, 2018: European Journal of Pain: EJP
Fuyuhiko Motoi, Yoshiaki Murakami, Ken-Ichi Okada, Ippei Matsumoto, Kenichiro Uemura, Sohei Satoi, Masayuki Sho, Goro Honda, Takumi Fukumoto, Hiroaki Yanagimoto, Shoichi Kinoshita, Masanao Kurata, Shuichi Aoki, Masamichi Mizuma, Hiroki Yamaue, Michiaki Unno
BACKGROUND: Survival after surgery for pancreatic adenocarcinoma (PA) is poor and heterogeneous, even for curative (R0) resection. Serum carbohydrate antigen (CA) 19-9 levels are important prognostic markers for resected PA. However, sustained elevation of CA19-9 in association with the patterns of recurrence has been rarely investigated. METHODS: Patients who underwent R0 resection (n = 539) were grouped according to postoperative serum CA19-9 levels (Group E: sustained elevation; Group N: no elevation)...
October 8, 2018: World Journal of Surgery
Nicholas Bird, Adrian McKenna, Declan Dunne, Ben Francis, Stephen Fenwick, Graeme Poston, Robert Jones, Hassan Malik
AIMS: Cholangiocarcinoma is a rare cancer arising from the biliary tree. Case series indicate that 25-40% of all borderline resectable primary tumours are potentially resectable. The Memorial Sloane Kettering System (MSKCC) stratifies patients for resectability by longitudinal and radial extension of the hilar tumour. The Bismuth-Corlette system describes the longitudinal extension of the tumour within the biliary duct system. We sought to validate and, if possible, augment these two scores within an independent validation cohort...
September 11, 2018: European Journal of Surgical Oncology
Takuhiro Yamaguchi, Yukio Kitajima, Yasuhiro Miyauchi, Kazutoshi Izawa, Masakazu Tanaka, Masatada Hirata, Yasunari Sadatsuki, Yoshihiro Ogawa
We aimed to investigate the incidence of bleeding-related adverse events (AEs) among patients with disseminated intravascular coagulation (DIC) receiving recombinant thrombomodulin (rTM) and those receiving other DIC treatments, the incidence by type of surgery, and the incidence when either blood transfusion or a hemostatic procedure was administered to treat DIC. In this cohort study, data were obtained from a large medical database (22 centers in Japan). The primary endpoint was the incidence rate of bleeding-related AEs by type of surgery...
2018: PloS One
Vikas Singh, Ghanshyambhai T Savani, Rodrigo Mendirichaga, Anil K Jonnalagadda, Mauricio G Cohen, Igor F Palacios
Advanced liver disease is a risk factor for cardiac surgery. However, liver dysfunction is not included in cardiac risk assessment models. We sought to identify trends in utilization, complications, and outcomes of patients with cirrhosis who underwent coronary artery bypass graft surgery (CABG). Using the National Inpatient Sample database, we identified patients with cirrhosis who underwent CABG from 2002 to 2014. Propensity-score matching was used to identify differences in in-hospital mortality and postoperative complications in cirrhosis and noncirrhosis patients...
September 7, 2018: American Journal of Cardiology
Jian Yang, Hai-Su Tao, Wei Cai, Wen Zhu, Dong Zhao, Hao-Yu Hu, Jun Liu, Chi-Hua Fang
BACKGROUND: The aim of this study was to assess the accuracy of actual resected liver volume (ARLV) in anatomical liver resections (ALRs) guided by 3-dimensional parenchymal staining using fusion indocyanine green fluorescence imaging (IGFI). METHODS: Patients eligible for hepatic resection were enrolled in the current study from January 2016 to November 2017. All patients underwent surgery planning based on Medical Image Three-Dimensional Visualization System (MI-3DVS) before the operation, in which predicted resected liver volumes (PRLVs) were calculated...
October 7, 2018: Journal of Surgical Oncology
Farhana Afroz, Alwyn Kist, Jin Hua, Yabin Zhou, Elke M Sokoya, Robert Padbury, Vincent Nieuwenhuijs, Greg Barritt
Rapamycin (sirolimus) is employed as an immunosuppressant following liver transplant, to inhibit the re-growth of cancer cells following liver resection for hepatocellular carcinoma (HCC), and for the treatment of advanced HCC. Rapamycin also induces the expression of antioxidant enzymes in the liver, suggesting that pretreatment with the drug could provide a potential strategy to reduce ischemia reperfusion injury following liver surgery. The aim of this study was to further investigate the actions of rapamycin in inducing expression of the antioxidant enzymes heme oxygenase-1 (HO-1) and peroxiredoxin-1 (Prx-1) in normal liver and in tumorigenic liver cells...
October 2, 2018: Experimental and Molecular Pathology
Xianwen Yuan, Jun Chen, Qi Cheng, Yinjuan Zhao, Pengzi Zhang, Xiaoyan Shao, Yan Bi, Xiaolei Shi, Yitao Ding, Xitai Sun, Bin Xue
BACKGROUND: This study is to investigate the association between the hepatic expression of Yin Yang 1 (YY1) and the progression of non-alcoholic fatty liver disease (NAFLD) in patients undergoing bariatric surgery. METHODS: Obese patients undergoing bariatric surgery were included. Liver tissues were subjected to the quantitative real-time PCR, Western blot analysis, and immunohistochemical assay, to determine the expression levels of YY1. RESULTS: Totally 88 patients were included...
October 3, 2018: BMC Gastroenterology
Tomohiko Taniai, Koichiro Haruki, Hiroaki Shiba, Shinji Onda, Taro Sakamoto, Katsuhiko Yanaga
Simultaneous resection of synchronous hepatocellular carcinoma (HCC) and pancreatic ductal adenocarcinoma (PDAC) is extremely rare. Case 1 is a 64-year-old woman, who had undergone anterior resection for rectal cancer 3 years earlier was pointed out to have a cystic tumor in the pancreatic tail and a solitary tumor in the liver. CT revealed a hypovascular tumor in the pancreatic tail and a liver tumor with early enhancement. With a diagnosis of simultaneous HCC and PDAC, she underwent laparotomy, in which intraoperative frozen section examination of the liver was compatible with HCC...
May 2018: Case Reports in Gastroenterology
Ning Zhang, Yatong Li, Mengyun Zhao, Xiaoyan Chang, Feng Tian, Qiang Qu, Xiaodong He
RATIONALE: Sarcomatous intrahepatic cholangiocarcinoma is a rare histological variant of cholangiocarcinoma (ICC). Previous medical literature has not mentioned the prevalence of this kind of disease, but a poorer prognosis than that of ordinary ICC was indicated. The diagnosis of the sarcomatous ICC is established on histopathological and immunohistochemical examinations. In this article, we present a new case of a patient with sarcomatous ICC who had no radiographic sign of intrahepatic tumor preoperatively...
September 2018: Medicine (Baltimore)
Kye-Yeung Park, Hoon-Ki Park, Hwan-Sik Hwang, Jae-Sook Ryu, Kyeong-Geun Lee, Ki-Seok Jang
Visceral larva migrans (VLM) is one of the clinical syndromes of human toxocariasis. We report a case of hepatic VLM presenting preprandial malaise and epigastric discomfort in a 58-year-old woman drinking raw roe deer blood. The imaging studies of the abdomen showed a 74-mm hepatic mass featuring hepatic VLM. Anti- Toxocara canis IgG was observed in enzyme-linked immunosorbent assay (ELISA) and western blot. Despite anthelmintic treatment, the patient complained of newly developed cough and skin rash with severe eosinophilia...
October 1, 2018: American Journal of Tropical Medicine and Hygiene
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