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Surgery Hepatic

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https://www.readbyqxmd.com/read/30517926/risk-factors-analysis-of-postoperative-pleural-effusion-after-liver-resection
#1
Kuei-Yen Tsai, Hsin-An Chen, Wan-Yu Wang, Ming-Te Huang
BACKGROUND: Pulmonary complications remain relatively high in morbidities that arise after liver surgery and are associated with increased length of hospital stay and higher cost. Identification of possible risk factors in this retrospective analysis may help reduce operative morbidity and achieve better outcomes. METHODS: In all, 363 consecutive patients underwent elective hepatectomies between July 2008 and November 2013 and these were identified and analyzed retrospectively...
December 5, 2018: Digestive Surgery
https://www.readbyqxmd.com/read/30517441/effect-of-local-application-of-alendronate-and-parathyroid-hormone-on-craniofacial-bone-repair-a-preliminary-study
#2
Frederico Ribeiro Deliberador, Aline Monise Sebastiani, Jennifer Gerber, Luana Bonetto, Gabriela Tórtora, Allan Fernando Giovanini, Tatiana Miranda Deliberador, Joao César Zielak, Rafaela Scariot
This study aimed to evaluate the effect of two methods of local application of alendronate and parathyroid hormone (PTH) on bone repair and the systemic implications. A critically sized defect (5 mm) was created in the cranial region of twenty-five male Wistar rats, and the bone removed was particulated, and grafted back to the defect with different treatments. The animals were randomly divided into five groups: A1- bone graft immersion in alendronate solution (3 mg/kg) for 5 minutes; P1- bone graft immersion in PTH solution (20 µg); A2- weekly local applications of alendronate 1 mg/kg; P2- weekly local applications of PTH (20 µg); C- no drugs were used...
September 2018: Brazilian Dental Journal
https://www.readbyqxmd.com/read/30517323/effects-of-different-periods-of-gastric-ischemia-on-liver-as-a-remote-organ1
#3
Maria Angélica Baron Magalhães, Andy Petroianu, Alfredo José Afonso Barbosa, Juliano Alves Figueiredo, Luiz Ronaldo Alberti, Jurandir Marcondes Ribas Filho
PURPOSE: To evaluate the hepatic changes associated with gastric ischemia. METHODS: Thirty male rabbits were studied, distributed in 3 groups (n=10). Group 1: ligature and section of the gastric vasculature and removal of the liver after three hours; Group 2: ligature and section of the gastric vasculature and removal of the liver after 6 hours; Group 3: ligature and section of the gastric vasculature and removal of the liver after 12 hours. Blood samples were collected immediately before surgery and after the determined time of ischemia in each group to evaluate the hepatic function...
November 2018: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/30517128/provider-knowledge-and-performance-in-medication-injection-safety-in-anesthesia-a-mixed-method-prospective-crosses-sectional-study
#4
Hasan Yusefzadeh, Alireza Didarloo, Bahram Nabilou
OBJECTIVES: Injection safety during anesthesia is a challenging health care issue in Iranian hospitals. Anesthesia is one of the most medication-intensive procedures in healthcare and injecting patients are an integral part of that care. The present study aimed to assess the status of medication injection safety practice in a teaching center. DESIGN, SETTING, PARTICIPANTS: A prospective cross-sectional study was done in 2014-2015 at a 500-bed secondary level teaching hospital affiliated with Urmia University of Medical Sciences, Iran...
2018: PloS One
https://www.readbyqxmd.com/read/30515423/enhanced-regeneration-and-hepatoprotective-effects-of-interleukin-22-fusion-protein-on-a-predamaged-liver-undergoing-partial-hepatectomy
#5
Heng Zhou, Guomin Xie, Yudi Mao, Ke Zhou, Ruixue Ren, Qihong Zhao, Hua Wang, Shi Yin
Liver ischemia-reperfusion injury (IRI) and regeneration deficiency are two major challenges for surgery patients with chronic liver disease. As a survival factor for hepatocytes, interleukin 22 (IL-22) plays an important role in hepatoprotection and the promotion of regeneration after hepatectomy. In this study, we aim to investigate the roles of an interleukin 22 fusion protein (IL-22-FP) in mice with a predamaged liver after a two-third partial hepatectomy (PHx). Predamaged livers in mice were induced by concanavalin A (ConA)/carbon tetrachloride (CCl4) following PHx with or without IL-22-FP treatment...
2018: Journal of Immunology Research
https://www.readbyqxmd.com/read/30510936/current-status-of-surgical-treatment-of-colorectal-liver-metastases
#6
REVIEW
Feng Xu, Bin Tang, Tian-Qiang Jin, Chao-Liu Dai
Liver metastasis (LM) is one of the major causes of death in patients with colorectal cancer (CRC). Approximately 60% of CRC patients develop LM during the course of their illness. About 85% of these patients have unresectable disease at the time of presentation. Surgical resection is currently the only curative treatment for patients with colorectal LM (CRLM). In recent years, with the help of modern multimodality therapy including systemic chemotherapy, radiation therapy, and surgery, the outcomes of CRLM treatment have significantly improved...
November 26, 2018: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/30510761/rates-of-colorectal-cancer-detection-in-screening-colonoscopy-post-appendicectomy-in-patients-50-years-and-over
#7
Sunny Dhadlie, Daniel Mehanna
Introduction: Acute appendicitis in older adults is relatively uncommon and could be the first presentation of an underlying colorectal carcinoma. Colonoscopy in these individuals affords the opportunity for earlier diagnosis and treatment. The finding of increased rates of colorectal cancer (CRC) with older patients who have had appendicitis was supported by a number of small studies and case reports in the early 1980s.With the advent of CT scanning and laparoscopic appendicectomy, increased ability to visualize the caecum has been achieved...
December 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/30510640/incidence-and-risk-factors-for-potentially-suboptimal-serum-concentrations-of-vancomycin-during-cardiac-surgery
#8
Paolo Cotogni, Cristina Barbero, Mauro Rinaldi
AIM: To investigate the incidence and risk factors for vancomycin concentrations less than 10 mg/L during cardiac surgery. METHODS: In this prospective study, patients undergoing cardiac surgery received a single dose of 1000 mg of vancomycin. Multiple arterial samples were drawn during surgery. Exclusion criteria were hepatic dysfunction; renal dysfunction; ongoing infectious diseases; solid or hematologic tumors; severe insulin-dependent diabetes; body mass index of < 17 or > 40 kg/m2 ; pregnancy or lactation; antibiotic, corticosteroid, or other immunosuppressive therapy; vancomycin or nonsteroidal anti-inflammatory drug therapy in the previous 2 wk; chemotherapy or radiation therapy in the previous 6 mo; allergy to vancomycin or cefazolin; drug abuse; cardiac surgery in the previous 6 mo; previous or scheduled organ transplantation; preoperative stay in the intensive care unit for more than 24 h; emergency procedure or lack of adequate preparation for surgery; and participation in another trial...
November 26, 2018: World Journal of Cardiology
https://www.readbyqxmd.com/read/30508952/thrombosis-in-the-portal-venous-system-caused-by-hypereosinophilic-syndrome-a-case-report
#9
Jinfeng Lin, Xiaoying Huang, Weihua Zhou, Suyan Zhang, Weiwei Sun, Yadong Wang, Ke Ren, Lijun Tian, Junxian Xu, Zhilong Cao, Zunguo Pu, Xudong Han
RATIONALE: Extensive thrombosis in the portal venous system caused by hypereosinophilic syndrome (HES) is rare, and there is no consensus on anticoagulant and thrombolytic treatments for arteriovenous thrombosis caused by HES. PATIENT CONCERNS: The clinical data of a patient with extensive thrombosis in his portal venous system (superior mesenteric, splenic, hepatic, and portal veins), renal artery thrombosis, and mesenteric thrombosis caused by HES with secondary gastrointestinal bleeding and intestinal necrosis were retrospectively analyzed...
November 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30507524/image-aligned-dynamic-liver-reconstruction-using-intra-operative-field-of-views-for-minimal-invasive-surgery
#10
Muhammad Nadeem Cheema, Anam Nazir, Bin Sheng, Ping Li, Jing Qin, Jinman Kim, Dagan Feng
During hepatic minimal invasive surgery (MIS), 3D reconstruction of a liver surface by interpreting the geometry of its soft-tissues is achieving attractions. One of the major issues to be addressed in MIS is liver deformation. Moreover, it severely inhibits free sight and dexterity of tissue manipulation which causes its intra-operative morphology and soft tissue motion altered as compared to its pre-operative shape. While many applications focus on 3D reconstruction of rigid or semi-rigid scenes, the techniques applied in hepatic MIS must be able to cope with a dynamic and deformable environment...
November 30, 2018: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/30506535/-application-of-overlapped-delta-shaped-anastomosis-technique-in-totally-laparoscopic-right-hemicolectomy
#11
Xuewei Wang, Peng Wang, Jun Hong, Hao Su, Jianwei Liang, Xishan Wang, Qian Liu, Haitao Zhou, Zhixiang Zhou
OBJECTIVE: To explore the safety and feasibility of the overlapped delta-shaped anastomosis (ODA) technique for cases undergoing totally laparoscopic right hemicolectomy (TLRH). METHODS: Clinical data of patients who underwent TLRH using the ODA technique or the modified delta-shaped anastomosis (MDA) technique at Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College from January 2016 to December 2017 were retrospectively analyzed...
November 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/30505229/giant-simple-biliary-cyst-infection-treated-with-minimally-invasive-percutaneous-drainage
#12
Rafael Dahmer Rocha, Priscila Mina Falsarella, Andre Arantes Pereira De Azevedo, Rodrigo Gobbo Garcia
We describe a minimally invasive alternative approach in a patient with infected hepatic cyst to stabilize the patient before definitive surgery. A 58-year-old man presented with fever and hypotension after 2 weeks of asthenia, chills, weight loss, slight abdominal pain, and a previous asymptomatic simple hepatic cyst. On ultrasound, a giant heterogeneous hepatic cyst with thick wall was noted. A positron emission tomography-computed tomography scan was indicated and demonstrated high uptake (standardized uptake value = 7...
October 2018: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/30503174/percutaneous-portal-vein-recanalization-using-self-expandable-nitinol-stents-in-patients-with-non-cirrhotic-non-tumoral-portal-vein-occlusion
#13
A Marot, J V Barbosa, R Duran, P Deltenre, A Denys
PURPOSE: The purpose of this study was to evaluate the feasibility, safety, and efficacy of portal vein recanalization (PVR) and propose a new classification for better selecting candidates with portal vein occlusion (PVO) in whom PVR could be feasible. MATERIALS AND METHODS: The charts of 15 non-cirrhotic patients in whom stent placement using a trans-hepatic approach was attempted for the treatment of PVO with cavernous transformation were reviewed. There were 12 men and 5 women with a mean age of 47±12 years (range: 22-60 years)...
November 28, 2018: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/30502273/modifications-to-expose-porta-hepatis-for-laparoscopic-portoenterostomy-easier-in-biliary-atresia
#14
Li Bing, Chen Wei-Bing, Huang Xia, Xia Shun-Lin, Zhang Feng-Nian, Wang Shou-Qing, Wang Ye-Bo
BACKGROUND: Laparoscopic Kasai portoenterostomy (LKPE) is generally regarded to have a poorer outcome for surgical treatment of uncorrectable biliary atresia. We herein described our initial experience of some modifications to make LKPE easier in the treatment of type III biliary atresia (BA). METHODS: During the period July 2012-October 2016, a total of 25 infants with type III BA were treated with a modified LKPE technique. A percutaneous suture was introduced just below the xiphoid process to snare the round ligament and retract the liver; other percutaneous stay sutures were then introduced to the fundus and neck of the gallbladder to elevate the liver and expose the porta hepatis...
January 2019: Journal of Surgical Research
https://www.readbyqxmd.com/read/30502004/biliary-atresia-20-40-year-follow-up-with-native-liver-in-an-italian-centre
#15
Filippo Parolini, Giovanni Boroni, Susanna Milianti, Luca Tonegatti, Andrea Armellini, Miguel Garcia Magne, Pierluigi Pedersini, Fabio Torri, Paolo Orizio, Stefano Benvenuti, Daniela Maria De Previde Prato, Daniele Alberti
INTRODUCTION: Biliary atresia (BA) represents the leading indication for liver transplantation in childhood. Only few studies reported the outcome of patients who survived more than 20 years on their native liver, and up to date there are no Italian data available. We reported our 40-year single centre experience with long-term follow-up of BA patients. MATERIALS AND METHODS: All consecutive patients who underwent Kasai portoenterostomy (KPE) for BA managed at our Institution between 1975 and 1996 were retrospectively reviewed...
November 6, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/30500456/imaging-of-liver-fusion-and-vascular-intra-hepatic-shunts-in-omphalopagus-conjoined-twins-the-role-of-a-double-ct-study
#16
Antonino Barletta, Marina Pace, Lorenzo D'Antiga, Maurizio Cheli, Giovanna Mangili, Sandro Sironi
Omphalopagus twins are joined ventrally in the umbilical region. In omphalopagus twins, liver's fusion is very frequent, being present in about 80% of cases. Two conjoined twins born in our Hospital were evaluated using plain x-rays, ultrasound (US), gastrointestinal xrays, Tc-99 hepatobiliary scintigraphy (SC) and contrast enhanced computed tomography (CT). There was no bony connection on conventional xrays, neither bowel communication on GI x-rays study. US demonstrated the fusion of left hepatic lobes and a not-quantifiable vascular shunt...
November 22, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/30500105/reasons-for-open-conversion-in-robotic-liver-surgery-a-systematic-review-with-pooled-analysis-of-more-than-1000-patients
#17
REVIEW
F Gheza, S Esposito, S Gruessner, A Mangano, E Fernandes, P C Giulianotti
BACKGROUND: Conversion to open during minimally invasive liver resection has a high rate. To identify the reasons to convert could help in defining a strategy to decrease the event "conversion". METHODS: A systematic review has been performed. Our large series of robotic hepatic resections was analyzed and included in the review. RESULTS: 50 papers were selected and carefully evaluated in full text. Twenty-nine were ultimately used for analysis, including all published robotic liver resections...
November 30, 2018: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/30499907/treatment-related-focal-nodular-hyperplasia-mimicking-liver-metastases
#18
Maria Elena Laino, Serena Monti, David S Klimstra, Laura H Tang, Lorenzo Mannelli
A 7-year-old patient with a stage 4 neuroblastoma underwent chemotherapy, surgery, myeloablative therapy, external beam radiotherapy, and Isoretinoin treatment. A posttreatment magnetic resonance examination performed administering gadoteric acid as contrast agent showed 2 new hypervascular hepatic lesions, suspicious for metastases. A second magnetic resonance imaging performed using a liver-specific contrast medium (gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid) demonstrated that these lesions were consistent with treatment-related focal nodular hyperplasia...
November 28, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/30496542/sex-hormone-binding-globulin-expression-correlates-with-acetyl-coa-carboxylase-and-triglyceride-content-in-human-liver
#19
Cristina Sáez-López, Maria Teresa Salcedo-Allende, Cristina Hernandez, Olga Simó-Servat, Rafael Simó, David M Selva
Context: There is emerging evidence that sex hormone binding globulin (SHBG) is significantly reduced in chronic metabolic diseases, including obesity and non-alcoholic fatty liver disease (NAFLD). We have recently reported using in vitro (HepG2 cells) and in vivo models (SHBG-C57BL/ksJ-db/db mice) that SHBG could play a role in arresting the progression of NAFLD by downregulating lipogenesis. Objective: The main aim of this study was to investigate the mechanisms by which SHBG prevents the hepatic lipogenesis by examining the relationship between SHBG and a key lipogenic enzyme such as Acetyl-CoA Carboxylase (ACC) in the liver of obese subjects...
November 28, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30496129/reduced-expression-of-thyroid-hormone-receptor-%C3%AE-in-human-nonalcoholic-steatohepatitis
#20
Christin Krause, Martina Grohs, Alexander El Gammal, Stefan Wolter, Hendrik Lehnert, Oliver Mann, Jens Mittag, Henriette Kirchner
Hepatic thyroid hormone signaling has an important role in the development and progression of nonalcoholic steatohepatitis (NASH). While the systemic levels of thyroid hormone might remain stable, there is evidence that the intracellular signaling machinery consisting of transporters, deiodinases and receptors could be altered in NASH. However, clinical material from human liver biopsies of individuals with NASH has not been studied to date. In a crossectional study, we analyzed 85 liver biopsies from patients with different stages of NASH that underwent bariatric surgery...
November 1, 2018: Endocrine Connections
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