Edoardo Botteri, Giulia Peveri, Paula Berstad, Vincenzo Bagnardi, Geir Hoff, Alicia K Heath, Amanda J Cross, Paolo Vineis, Laure Dossus, Mattias Johansson, Heinz Freisling, Komodo Matta, Inge Huybrechts, Sairah L F Chen, Kristin B Borch, Torkjel M Sandanger, Therese H Nøst, Christina C Dahm, Christian S Antoniussen, Sandar Tin Tin, Agnès Fournier, Chloé Marques, Fanny Artaud, Maria-José Sánchez, Marcela Guevara, Carmen Santiuste, Antonio Agudo, Rashmita Bajracharya, Verena Katzke, Fulvio Ricceri, Claudia Agnoli, Manuela M Bergmann, Matthias B Schulze, Salvatore Panico, Giovanna Masala, Anne Tjønneland, Anja Olsen, Tanja Stocks, Jonas Manjer, Amaia Aizpurua-Atxega, Elisabete Weiderpass, Elio Riboli, Marc J Gunter, Pietro Ferrari
In this study, we aimed to provide novel evidence on the impact of changing lifestyle habits on cancer risk. In the EPIC cohort, 295,865 middle-aged participants returned a lifestyle questionnaire at baseline and during follow-up. At both timepoints, we calculated a healthy lifestyle index (HLI) score based on cigarette smoking, alcohol consumption, body mass index and physical activity. HLI ranged from 0 (most unfavourable) to 16 (most favourable). We estimated the association between HLI change and risk of lifestyle-related cancers-including cancer of the breast, lung, colorectum, stomach, liver, cervix, oesophagus, bladder, and others-using Cox regression models...
January 5, 2024: European Journal of Epidemiology