keyword
https://read.qxmd.com/read/38180998/scientific-clickbait-examining-media-coverage-and-readability-in-genome-wide-association-research
#21
JOURNAL ARTICLE
José J Morosoli, Lucía Colodro-Conde, Fiona Kate Barlow, Sarah E Medland
In the present study, we analyzed a large corpus of English-language online media articles covering genome-wide association studies (GWAS), exemplifying the use of computational methods to study science communication in biological sciences. We analyzed trends in media coverage, readability, themes, and mentions of ethical and social issues, in over 5,000 websites published from 2005 to 2018 from 3,555 GWAS publications on 1,943 different traits, identified via GWAS Catalog using a text-mining approach to inform the discussion about genetic literacy and media coverage...
2024: PloS One
https://read.qxmd.com/read/38180593/lifestyle-changes-in-middle-age-and-risk-of-cancer-evidence-from-the-european-prospective-investigation-into-cancer-and-nutrition
#22
JOURNAL ARTICLE
Edoardo Botteri, Giulia Peveri, Paula Berstad, Vincenzo Bagnardi, Geir Hoff, Alicia K Heath, Amanda J Cross, Paolo Vineis, Laure Dossus, Mattias Johansson, Heinz Freisling, Komodo Matta, Inge Huybrechts, Sairah L F Chen, Kristin B Borch, Torkjel M Sandanger, Therese H Nøst, Christina C Dahm, Christian S Antoniussen, Sandar Tin Tin, Agnès Fournier, Chloé Marques, Fanny Artaud, Maria-José Sánchez, Marcela Guevara, Carmen Santiuste, Antonio Agudo, Rashmita Bajracharya, Verena Katzke, Fulvio Ricceri, Claudia Agnoli, Manuela M Bergmann, Matthias B Schulze, Salvatore Panico, Giovanna Masala, Anne Tjønneland, Anja Olsen, Tanja Stocks, Jonas Manjer, Amaia Aizpurua-Atxega, Elisabete Weiderpass, Elio Riboli, Marc J Gunter, Pietro Ferrari
In this study, we aimed to provide novel evidence on the impact of changing lifestyle habits on cancer risk. In the EPIC cohort, 295,865 middle-aged participants returned a lifestyle questionnaire at baseline and during follow-up. At both timepoints, we calculated a healthy lifestyle index (HLI) score based on cigarette smoking, alcohol consumption, body mass index and physical activity. HLI ranged from 0 (most unfavourable) to 16 (most favourable). We estimated the association between HLI change and risk of lifestyle-related cancers-including cancer of the breast, lung, colorectum, stomach, liver, cervix, oesophagus, bladder, and others-using Cox regression models...
January 5, 2024: European Journal of Epidemiology
https://read.qxmd.com/read/38175589/epidemiology-of-cancer
#23
JOURNAL ARTICLE
Stephen M Schwartz
BACKGROUND: Cancers are a large and heterogeneous group of malignant tumors that collectively accounted for approximately 600 000 US deaths in 2020; only heart disease claimed more lives. A large amount of knowledge has accumulated regarding the epidemiology of most cancer types, including their causes. CONTENT: The cancer types most frequently diagnosed among adults in most high-income countries are lung, colorectal, female breast, cutaneous melanoma, and prostate...
January 4, 2024: Clinical Chemistry
https://read.qxmd.com/read/38172846/quality-of-life-among-french-breast-cancer-survivors-in-comparison-with-cancer-free-women-the-seintinelles-study
#24
JOURNAL ARTICLE
Alexandra-Cristina Paunescu, Marie Préau, Cyrille Delpierre, Guillemette Jacob, Myriam Pannard, Lidia Delrieu, Marina Kvaskoff
BACKGROUND: Health-Related Quality of life (HRQoL) in cancer survivors can be significantly affected in the long-term by various consequences resulting from differing levels of severity of cancer and its treatments. Our objective was to identify factors associated with HRQoL in breast cancer survivors (BCSs) and cancer-free women (CFWs). METHODS: We conducted a cross-sectional study in Seintinelles volunteers who answered online questionnaires between September 15, 2020 and February 5, 2021...
January 3, 2024: BMC Women's Health
https://read.qxmd.com/read/38147061/physical-activity-and-mammographic-density-in-japanese-women
#25
JOURNAL ARTICLE
Mihye Lee, Rina Kotake, Hideko Yamauchi
BACKGROUND: Dense breast is one of the strong risk factors for breast cancer among women. While it has been established that physical activity is associated with decreased risk for breast cancer, results have been inconsistent in terms of mammographic density. Thus, we examined physical activity in relation to mammographic density among Japanese women in Tokyo. METHODS: We used 123,026 records from 33,698 Japanese women without a history of breast cancer who got mammograms at St...
December 26, 2023: Cancer Epidemiology, Biomarkers & Prevention
https://read.qxmd.com/read/38115125/association-between-allostatic-load-and-breast-cancer-risk-a-cohort-study
#26
JOURNAL ARTICLE
Yufan Guan, Jie Shen, Juan Lu, Bernard F Fuemmeler, Lisa S Shock, Hua Zhao
BACKGROUND: Allostatic load (AL) reflects the collective load of chronic stress during lifetime. Previous studies have shown that higher AL is associated with poor clinical outcomes among breast cancer patients. However, the relationship between AL and breast cancer risk is still unclear. METHODS: To fill the gap, we analyzed the association between AL and the development of breast cancer in 181,455 women identified from the UK Biobank. RESULTS: During the follow-up from 2006 to 2020, 5,701 women were diagnosed with incident breast cancer...
December 19, 2023: Breast Cancer Research: BCR
https://read.qxmd.com/read/38082340/current-status-and-challenges-of-breast-cancer-prevention-dna-methylation-would-lead-to-groundbreaking-progress-in-breast-cancer-prevention
#27
REVIEW
Takahiro Tsukioki, Seema A Khan, Tadahiko Shien
The number of breast cancer patients is increasing worldwide. Furthermore, breast cancer often develops in young people, even those only in their 30s, who play a central role in their families and society. Results from many cohort studies suggest that dietary factors, alcohol consumption, lack of physical activity, obesity, nulliparity, breastfeeding, oral contraceptive use, fertility treatment and hormone replacement therapy are risk factors for breast cancer. However, the effects of lifestyle habits on the human body are complexly intertwined with various factors, and the effects vary from person to person depending on their constitution, etc...
December 12, 2023: Genes and Environment: the Official Journal of the Japanese Environmental Mutagen Society
https://read.qxmd.com/read/38060977/cancer-risk-factors-in-southern-brazil-report-of-a-comprehensive-matched-case-control-study
#28
JOURNAL ARTICLE
Juliana Giacomazzi, Patricia Klarmann Ziegelmann, Samanta da Costa, Camila Matzenbacher Bittar, Fernando Mariano Obst, Clévia Rosset, Gabriel S Macedo, Hugo Bock, Thais Canal, Mari Ines Paese, Jean Lucas Benvenuti, Maria Carolina Buj, Patricia Ashton-Prolla, José Roberto Goldim, Roberta Pozza
PURPOSE: To evaluate cancer risk factors among cancer cases and controls from Southern Brazil, to analyze a multigene hereditary panel testing (MGPT, 26 genes) for breast cancer (BC) and colorectal cancer (CCR) cases diagnosed age younger than 50 years and to characterize them for hereditary cancer syndrome (HCS) phenotypes. METHODS: A case-control (matched by age group and sex) study was conducted on regional cancer. Data on exposure factors and first-/second-degree family history of cancer (1/2FHC) were collected...
September 2023: JCO global oncology
https://read.qxmd.com/read/38028735/circulating-long-non-coding-rna-ewsat1-acts-as-a-liquid-biopsy-marker-for-esophageal-squamous-cell-carcinoma-a-pilot-study
#29
JOURNAL ARTICLE
Vivek Uttam, Manjit Kaur Rana, Uttam Sharma, Karuna Singh, Aklank Jain
The widespread public health problem of esophageal squamous cell carcinoma (ESCC) is the cause of an increasing number of deaths each year due to delayed diagnosis. Therefore, we require specific and sensitive new biomarkers to manage ESCC better. The detection of diseases, such as cancer, can now be achieved through non-invasive circulating blood-based methods. Blood-based circulating non-coding RNAs, such as miRNA and lncRNA, have been extensively used as valuable markers for lung, esophageal, and breast cancer diagnostic purposes, as quoted in our previous research...
March 2024: Non-Coding RNA Research
https://read.qxmd.com/read/38019269/alcohol-smoking-and-risks-of-breast-cancer-recurrence-and-mortality-among-women-with-luminal-triple-negative-and-her2-overexpressing-breast-cancer
#30
JOURNAL ARTICLE
Nicole C Loroña, Megan Othus, Kathleen E Malone, Hannah M Linden, Mei-Tzu C Tang, Christopher I Li
BACKGROUND: This study evaluates the relationship between smoking, alcohol, and breast cancer outcomes according to molecular subtype. METHODS: This population-based prospective cohort consisted of 3,876 women aged 20-69 diagnosed with a first primary invasive breast cancer from 2004 through 2015 in the Seattle-Puget Sound region. Breast cancer was categorized into three subtypes based on estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression: luminal (ER+), triple-negative (TN) (ER-/PR-/HER2-), and HER2-overexpressing (H2E) (ER-/HER2+)...
November 29, 2023: Cancer Epidemiology, Biomarkers & Prevention
https://read.qxmd.com/read/37998426/temporal-evolution-and-associated-factors-of-adherence-to-mammography-screening-among-women-in-spain-results-from-two-national-health-surveys-2017-2020
#31
JOURNAL ARTICLE
Silvia Portero de la Cruz, Luis M Béjar, Jesús Cebrino
Ensuring equity in cancer screening is recommended by the European Commission. Despite the fact that breast cancer screening is a free population-based program in Spain, there remains considerable variation in the adherence to screening rate among population groups. This study was designed to describe the adherence of breast cancer screening in women in Spain, to evaluate the evolution in the period from 2017 to 2020, and to determine the variables that influence choosing to undergo breast cancer screening...
November 9, 2023: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/37929890/-nutrition-in-breast-cancer-genesis
#32
JOURNAL ARTICLE
Bricia López-Plaza, Laura M Bermejo, Viviana Loria-Kohen, Edwin Fernández-Cruz
Breast cancer is the most prevalent tumor in women, ranking first in incidence and mortality in many countries. Although the causes of breast cancer are complex and multifactorial, nutritional factors and those related to nutritional status play an important role in the development of the disease. In this way, factors that increase breast cancer risk have been identified, such as weight gain, the amount of adipose tissue, waist circumference, alcohol consumption or the consumption of red meat and processed meat, while other factors have been identified that reduce the risk, such as eating fruits and vegetables...
October 19, 2023: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/37914956/the-interaction-of-diet-alcohol-genetic-predisposition-and-the-risk-of-breast-cancer-a-cohort-study-from-the-uk-biobank
#33
JOURNAL ARTICLE
Pingxiu Zhu, Yanyu Zhang, Qianni Chen, Wenji Qiu, Minhui Chen, Lihua Xue, Moufeng Lin, Haomin Yang
BACKGROUND: Dietary factors have consistently been associated with breast cancer risk. However, there is limited evidence regarding their associations in women with different genetic susceptibility to breast cancer, and their interaction with alcohol consumption is also not well understood. METHODS: We analyzed data from 261,853 female participants in the UK Biobank. Multivariable adjusted Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for associations between dietary factors and breast cancer risk...
November 1, 2023: European Journal of Nutrition
https://read.qxmd.com/read/37905315/cancer-risk-based-on-alcohol-consumption-levels-a-comprehensive-systematic-review-and-meta-analysis
#34
JOURNAL ARTICLE
Seunghee Jun, Hyunjin Park, Ui-Jeong Kim, Eun Jeong Choi, Hye Ah Lee, Bomi Park, Soon Young Lee, Sun Ha Jee, Hyesook Park
OBJECTIVES: Alcohol consumption is a well-established risk factor for cancer. Despite extensive research into the relationship between alcohol consumption and cancer risk, the effect of light alcohol consumption on cancer risk remains a topic of debate. To contribute to this discourse, we conducted a comprehensive systematic review and meta-analysis. METHODS: Our systematic review aimed to investigate the associations between different levels of alcohol consumption and the risk of several cancer types...
October 16, 2023: Epidemiology and Health
https://read.qxmd.com/read/37886198/associations-between-metabolic-dysfunction-associated-fatty-liver-disease-and-extrahepatic-cancers-a-cohort-in-china
#35
JOURNAL ARTICLE
Xiaojie Yuan, Xiaomo Wang, Shouling Wu, Shuohua Chen, Yanhong Wang, Jierui Wang, Ying Lu, Yuanyuan Sun, Qingjiang Fu, Li Wang
BACKGROUND: To evaluate the associations between a new definition of metabolic dysfunction-associated fatty liver disease (MAFLD) and extrahepatic cancers and compare with nonalcoholic fatty liver disease (NAFLD). METHODS: We enrolled 151,391 Chinese participants in the Kailuan cohort. Hepatic steatosis was detected by abdominal ultrasound. Fine and Gray competing risk regression models were used to estimate hazard ratios (HRs) and 95% confidence interval (CI) between MAFLD and extrahepatic cancers...
October 1, 2023: Hepatobiliary Surgery and Nutrition
https://read.qxmd.com/read/37802887/public-awareness-of-the-alcohol-cancer-link-in-the-eu-and-uk-a-scoping-review
#36
JOURNAL ARTICLE
Daša Kokole, Carina Ferreira-Borges, Gauden Galea, Alexander Tran, Jürgen Rehm, Maria Neufeld
BACKGROUND: Alcohol increases cancer risk, but less is known about public awareness of this link. This scoping review summarizes recent findings on the public awareness of alcohol as a cancer risk factor in European Union and UK. METHODS: Four databases (Web of Science, MEDLINE, PsycInfo, CINAHL) were searched for papers containing data on awareness of alcohol as cancer risk factor in EU or UK published between January 2017 and December 2022, and complemented with grey literature searches...
October 6, 2023: European Journal of Public Health
https://read.qxmd.com/read/37799951/risk-factors-for-breast-cancer-among-women-in-ekurhuleni-metropolitan-municipality-gauteng-province-of-south-africa-2017%C3%A2-2020-a-case-control-study
#37
JOURNAL ARTICLE
Sizeka A Mashele, Thembekile B Zwane, Lazarus Kuonza, Mazvita M Muchengeti, Lactatia Motsuku
INTRODUCTION: Breast cancer (BC) is the most common cancer among women in South Africa (SA), with an age-standardised incidence rate of 52.6 and an age-standardised mortality rate of 16.0 per 100,000 population. There is a paucity of evidence on the risk factors for BC among women of all races in SA. Given the rising prevalence of BC in SA, literature-based evidence is critical for the appropriate dissemination of preventative measures. This study aimed to identify the risk factors associated with the development of BC among women in Ekhuruleni Metropolitan Municipality...
2023: Ecancermedicalscience
https://read.qxmd.com/read/37789587/the-dose-response-relationship-of-pre-menopausal-alcohol-consumption-with-age-at-menopause-a-population-study-of-280%C3%A2-497-women-in-norway
#38
JOURNAL ARTICLE
Julie R Langås, Anne Eskild, Solveig Hofvind, Elisabeth K Bjelland
BACKGROUND: Previous research suggests that alcohol consumption is associated with high age at menopause. Yet, knowledge about the dose-response relationship is inconsistent. Thus, we studied the pattern of the association of pre-menopausal alcohol consumption with age at natural menopause. METHODS: We performed a retrospective population-based study using self-reported data from 280 497 women aged 50-69 years attending the Norwegian breast cancer screening programme (BreastScreen Norway) during 2006-15...
October 3, 2023: International Journal of Epidemiology
https://read.qxmd.com/read/37787924/lifetime-alcohol-consumption-patterns-and-young-onset-breast-cancer-by-subtype-among-non-hispanic-black-and-white-women-in-the-young-women-s-health-history-study
#39
JOURNAL ARTICLE
Kelly A Hirko, Darek R Lucas, Dorothy R Pathak, Ann S Hamilton, Lydia M Post, Ugonna Ihenacho, Nicole Bohme Carnegie, Richard T Houang, Kendra Schwartz, Ellen M Velie
PURPOSE: The role of alcohol in young-onset breast cancer (YOBC) is unclear. We examined associations between lifetime alcohol consumption and YOBC in the Young Women's Health History Study, a population-based case-control study of breast cancer among Non-Hispanic Black and White women < 50 years of age. METHODS: Breast cancer cases (n = 1,812) were diagnosed in the Metropolitan Detroit and Los Angeles County SEER registry areas, 2010-2015...
October 3, 2023: Cancer Causes & Control: CCC
https://read.qxmd.com/read/37784763/canto-skin-toxicities-evaluation-of-a-multicenter-large-prospective-cohort-of-irradiated-patients-for-early-stage-breast-cancer
#40
JOURNAL ARTICLE
S Allali, M Carton, T Sarrade, S Everhard, S Rivera, Y Ghannam, K Peignaux, P Guilbert, C Chara-Brunaud, J Blanchecotte, D Pasquier, S Racadot, C Bourgier, P Cottu, Y Kirova
PURPOSE/OBJECTIVE(S): Skin damage is a common toxicity during oncology management. Its assessment and understanding of the factors influencing its occurrence, is a major issue in the management of patients treated for an early breast cancer (BC). MATERIALS/METHODS: CANTO (NCT01993498) is a prospective, multicentric, clinical cohort study of 11 400 patients with stage I-III BC, treated in 26 French cancer centers. In this study, we will evaluate the 8561 patients during their overall management for a BC...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
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