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https://www.readbyqxmd.com/read/30079469/childhood-trauma-is-predictive-for-clinical-staging-alcohol-consumption-and-emotional-symptoms-in-patients-with-head-and-neck-cancer
#1
Bruna Amélia M Sarafim-Silva, Gabrielle D Duarte, Maria Lúcia M M Sundefeld, Éder Ricardo Biasoli, Glauco I Miyahara, Daniel Galera Bernabé
BACKGROUND: Traumatic events in childhood have been associated with the occurrence of anxiety and depression in adulthood. This relation has been investigated in patients with breast cancer; however, it has been little explored in patients with other types of cancer. The objective of this study was to evaluate the occurrence of childhood trauma in patients with head and neck cancer and its association with clinicopathological variables and anxiety and depression levels. METHODS: The study included 110 patients with head and neck squamous cell carcinoma (HNSCC) before they started cancer treatment...
August 6, 2018: Cancer
https://www.readbyqxmd.com/read/30034993/mendelian-randomization-studies-of-cancer-risk-a-literature-review
#2
Brandon L Pierce, Peter Kraft, Chenan Zhang
Purpose of review: In this paper, we summarize prior studies that have used Mendelian Randomization (MR) methods to study the effects of exposures, lifestyle factors, physical traits, and/or biomarkers on cancer risk in humans. Many such risk factors have been associated with cancer risk in observational studies, and the MR approach can be used to provide evidence as to whether these associations represent causal relationships. MR methods require a risk factor of interest to have known genetic determinants that can be used as proxies for the risk factor (i...
June 2018: Current Epidemiology Reports
https://www.readbyqxmd.com/read/30014030/occupational-inequalities-in-female-cancer-incidence-in-japan-hospital-based-matched-case-control-study-with-occupational-class
#3
Masayoshi Zaitsu, Rena Kaneko, Takumi Takeuchi, Yuzuru Sato, Yasuki Kobayashi, Ichiro Kawachi
Background: Socioeconomic inequalities in female cancer incidence have previously been undocumented in Japan. Methods: Using a nationwide inpatient dataset (1984-2016) in Japan, we identified 143,806 female cancer cases and 703,157 controls matched for sex, age, admission date, and admitting hospital, and performed a hospital-based matched case-control study. Based on standardized national classification, we categorized patients' socioeconomic status (SES) by occupational class (blue-collar, service, professional, manager), cross-classified by industry sector (blue-collar, service, white-collar)...
August 2018: SSM—Population Health
https://www.readbyqxmd.com/read/29996806/a-prospective-cohort-study-of-school-going-children-investigating-reproductive-and-neurobehavioral-health-effects-due-to-environmental-pesticide-exposure-in-the-western-cape-south-africa-study-protocol
#4
Shala Chetty-Mhlanga, Wisdom Basera, Samuel Fuhrimann, Nicole Probst-Hensch, Steven Delport, Mufaro Mugari, Jennifer Van Wyk, Martin Röösli, Mohamed Aqiel Dalvie
BACKGROUND: Research on reproductive health effects on children from low-level, long-term exposure to pesticides currently used in the agricultural industry is limited and those on neurobehavioral effects have produced conflicting evidence. We aim at investigating the association between pesticide exposure on the reproductive health and neurobehavior of children in South Africa, by including potential relevant co-exposures from the use of electronic media and maternal alcohol consumption...
July 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29963111/interactions-between-alcohol-consumption-and-adjuvant-hormone-therapy-in-relation-to-breast-cancer-free-survival
#5
Allison Kowalski, Catherine Woodstock Striley, Deepthi Satheesa Varma, Kathleen Marie Egan, Lusine Yaghjyan
Purpose: Alcohol consumption is associated with an increase in breast cancer risk, but findings on the association of alcohol with survival after breast cancer diagnosis have been inconsistent. Further, whether these associations could differ by adjuvant hormone therapy status is unknown. We examined interactions between alcohol consumption and adjuvant hormone therapy in relation to breast cancer-free survival among women with a primary breast cancer diagnosis. Methods: Participants in this study included 1,399 women diagnosed with primary breast cancer between 2007 and 2012 at the Moffitt Cancer Center...
June 2018: Journal of Breast Cancer
https://www.readbyqxmd.com/read/29951370/cancer-incidence-in-europe-an-ecological-analysis-of-nutritional-and-other-environmental-factors
#6
Pavel Grasgruber, Eduard Hrazdira, Martin Sebera, Tomas Kalina
The aim of this work was to offer an ecological alternative to conventional observational studies and identify factors potentially associated with cancer incidence in Europe. The incidence of 24 types of cancer in 39 European countries (2012) was compared with a long-term mean supply of 68 food items from the FAOSTAT database (1993-2011) and some other variables such as smoking, body mass index, raised cholesterol, and socioeconomic indicators. In addition to simple Pearson linear correlations, the data were analyzed via factor analyses and penalized regression methods...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29938357/interactions-of-alcohol-and-postmenopausal-hormone-use-in-regards-to-mammographic-breast-density
#7
Lusine Yaghjyan, Graham Colditz, Heather Eliassen, Bernard Rosner, Aleksandra Gasparova, Rulla M Tamimi
PURPOSE: We investigated the association of alcohol intake with mammographic breast density in postmenopausal women by their hormone therapy (HT) status. METHODS: This study included 2,100 cancer-free postmenopausal women within the Nurses' Health Study and Nurses' Health Study II cohorts. Percent breast density (PD), absolute dense (DA), and non-dense areas (NDA) were measured from digitized film mammograms using a computer-assisted thresholding technique; all measures were square root transformed...
June 25, 2018: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29934679/-xenobiotics-and-pathogens-in-breast-milk-a-risk-for-the-child
#8
REVIEW
Stephanie Padberg, Christoph Bührer, Juliane Menzel, Cornelia Weikert, Christof Schaefer, Klaus Abraham
Although breast milk is the best diet in the first few months of life, risks can arise for the breast-fed infant. The article gives a comprehensive overview of possible risks regarding xenobiotics and pathogens in mother's milk, including medications, smoking, alcohol consumption, coffee consumption, persistent environmental contaminants and residues as well as infections.Where drug therapy is indicated, suitable medications are available for most conditions nowadays, so that prolonged nursing breaks or even weaning is not required...
June 22, 2018: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/29887787/modifiable-lifestyle-factors-opportunities-for-hereditary-breast-cancer-prevention-a-narrative-review
#9
REVIEW
Jacqueline Lammert, Sabine Grill, Marion Kiechle
Increasing rates of obesity, lack of physical activity, sedentary behavior, and frequent alcohol consumption are major lifestyle-related risk factors for breast cancer. In fact, it has been estimated that about one-third of breast cancer cases are attributable to factors women can change. Most research has focused on examining the impact of one single exposure on breast cancer risk while adjusting for other risk modifiers. Capitalizing on big data, major efforts have been made to evaluate the combined impact of well-established lifestyle factors on overall breast cancer risk...
April 2018: Breast Care
https://www.readbyqxmd.com/read/29887784/can-nutrition-lower-the-risk-of-recurrence-in-breast-cancer
#10
REVIEW
Julia Weigl, Hans Hauner, Dagmar Hauner
Background: The impact of diet on breast cancer prognosis is poorly understood. Therefore, we conducted a literature search summarizing the current evidence on the effect of diet on breast cancer recurrence and mortality. Methods: The PubMed database was searched for original studies, reviews, and meta-analyses published between 2010 and 2017. Studies related to diet, dietary patterns, special diets or specific dietary factors, and breast cancer recurrence or mortality were included...
April 2018: Breast Care
https://www.readbyqxmd.com/read/29843260/is-breast-best-examining-the-effects-of-alcohol-and-cannabis-use-during-lactation
#11
R A Brown, H Dakkak, J A Seabrook
Maternal drug use during lactation may have adverse effects on the health of their children. Two common drugs used during this period are alcohol and cannabis. A literature search was conducted using PubMed, CINAHL, Nursing and Allied Health, and Google Scholar with the following search terms: marijuana, cannabis, THC, alcohol, ethanol, breastfeeding, lactation, and breastmilk. The search strategy was restricted to papers since the year 2000, and limited to English language journals. Reference lists were also used to capture any articles that were missed from the database searches...
May 23, 2018: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/29765171/risks-and-protective-factors-for-triple-negative-breast-cancer-with-a-focus-on-micronutrients-and-infections
#12
Dagmar Horakova, Katerina Bouchalova, Karel Cwiertka, Ladislav Stepanek, Jana Vlckova, Helena Kollarova
Triple negative breast cancer (TNBC) is an aggressive form of breast cancer (BC) with a poor prognosis. Second, patients cannot benefit from targeted therapy, except for those with BRCA1/2 mutations, for whom poly (ADP-ribose) polymerase (PARP) inhibition therapy using olaparib has recently been approved. As global priorities continue to be epidemiological analysis of BC risk factors and early diagnosis, this review focuses on the risks and protective factors associated with TNBC. A PubMed keyword search for new knowledge on the risks and protective factors for TNBC was carried out...
June 2018: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/29739641/avoidable-cancers-in-the-nordic-countries-the-impact-of-alcohol-consumption
#13
Therese M-L Andersson, Gerda Engholm, Eero Pukkala, Magnus Stenbeck, Laufey Tryggvadottir, Hans Storm, Elisabete Weiderpass
BACKGROUND: Alcohol consumption is an important and preventable cause of cancer. The aim of this study was to quantify the proportion of the cancer burden in the Nordic countries linked to alcohol and estimate the potential for cancer prevention by changes in alcohol consumption. METHODS: Using the Prevent macro-simulation model, the number of cancer cases in the Nordic countries over a 30-year period (2016-2045) was modelled for six sites, under different scenarios of changing alcohol consumption, and compared to the projected number of cases if constant alcohol consumption prevailed...
May 5, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29708591/alcohol-smoking-and-risk-of-her2-overexpressing-and-triple-negative-breast-cancer-relative-to-estrogen-receptor-positive-breast-cancer
#14
Michelle L Baglia, Linda S Cook, C Mei-Tzu, Charles Wiggins, Deirdre Hill, Peggy Porter, Christopher I Li
Epidemiological evidence is limited on how alcohol consumption and smoking are associated with risk of different subtypes of breast cancer, such as triple-negative (TN) and human epidermal growth factor receptor 2-overexpressing (H2E) breast cancers, which may have different etiologies from more common luminal (estrogen receptor [ER+]) breast cancers. In this population-based case-case study, we evaluated the association between alcohol, smoking, and risk of H2E and TN breast cancer, compared with ER+ breast cancers, among women aged 20-69 years...
April 30, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29696713/national-cancer-societies-and-their-public-statements-on-alcohol-consumption-and-cancer-risk
#15
Gopal Amin, Michael Siegel, Timothy Naimi
BACKGROUND AND AIMS: Studies have shown that alcohol consumption is a risk factor for oral, pharyngeal, laryngeal, esophageal, liver, colon, rectal and breast cancer. It would therefore be expected that cancer prevention organizations would incorporate these facts into their public stance on the consumption of alcohol. The aims of this study were to: (1) assess how national cancer societies in developed English-speaking countries [i.e. English-speaking countries belonging to the Organization for Economic Co-operation and Development (OECD)] communicate alcohol-related cancer risk to the public and (2) compare whether these organization's advocacy of increased alcohol taxes is in line with their advocacy of tobacco tax increases to reduce cancer risk...
April 25, 2018: Addiction
https://www.readbyqxmd.com/read/29694586/-guidance-on-breastfeeding-in-primary-health-care-and-the-association-with-exclusive-breastfeeding
#16
Jessica de Souza Alves, Maria Inês Couto de Oliveira, Rosane Valéria Viana Fonseca Rito
This article aims to analyze the association between guidance on breastfeeding in primary health care and exclusive breastfeeding. It involved a cross-sectional study conducted in 2013 in the city of Rio de Janeiro, Brazil, by means of interviews with 429 mothers of infants below six months of age in primary care units. We estimated adjusted prevalence ratios by Poisson regression. In the final model, the variables associated with the outcome (p ≤ 0.05) were retained. The prevalence of exclusive breastfeeding was 50...
April 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29678902/development-of-a-breast-cancer-risk-prediction-model-for-women-in-nigeria
#17
Shengfeng Wang, Temidayo Ogundiran, Adeyinka Ademola, Oluwasola A Olayiwola, Adewunmi Adeoye, Adenike Sofoluwe, Imran Morhason-Bello, Stella Odedina, Imaria Agwai, Clement Adebamowo, Millicent Obajimi, Oladosu Ojengbede, Olufunmilayo I Olopade, Dezheng Huo
Background: Risk prediction models have been widely used to identify women at higher risk of breast cancer. We aimed to develop a model for absolute breast cancer risk prediction for Nigerian women. Methods: A total of 1,811 breast cancer cases and 2,225 controls from the Nigerian Breast Cancer Study (NBCS, 1998-2015) were included. Subjects were randomly divided into the training and validation sets. Incorporating local incidence rates, multivariable logistic regressions were used to develop the model. Results: The NBCS model included age, age at menarche, parity, duration of breastfeeding, family history of breast cancer, height, body mass index, benign breast diseases, and alcohol consumption...
June 2018: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29651647/an-estrogen-related-lifestyle-score-is-associated-with-risk-of-postmenopausal-breast-cancer-in-the-plco-cohort
#18
Mark A Guinter, Alexander C McLain, Anwar T Merchant, Dale P Sandler, Susan E Steck
PURPOSE: Healthy or unhealthy lifestyle behaviors are often adopted together. We aimed to investigate the combined effect of estrogen-related lifestyle factors on postmenopausal breast cancer risk. METHODS: Data from 27,153 women enrolled in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial were used. We created an estrogen-related lifestyle score (ERLS) by incorporating a previously developed measure of estrogenic diet, alcohol intake, body mass index (BMI), and physical activity...
August 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29625601/connecting-the-dots-between-breast-cancer-obesity-and-alcohol-consumption-in-middle-aged-women-ecological-and-case-control-studies
#19
E R Miller, C Wilson, J Chapman, I Flight, A-M Nguyen, C Fletcher, Ij Ramsey
BACKGROUND: Breast cancer (BC) incidence in Australian women aged 45 to 64 years ('middle-aged') has tripled in the past 50 years, along with increasing alcohol consumption and obesity in middle-age women. Alcohol and obesity have been individually associated with BC but little is known about how these factors might interact. Chronic psychological stress has been associated with, but not causally linked to, BC. Here, alcohol could represent the 'missing link' - reflecting self-medication...
April 6, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29615419/awareness-of-the-link-between-alcohol-consumption-and-cancer-across-the-world-a-review
#20
REVIEW
Jennifer K Scheideler, William M P Klein
Since 1988, the International Agency for Research on Cancer has classified alcohol as a Group 1 carcinogen, the highest level of risk. Growing evidence suggests that alcohol increases the risk of several types of cancer including breast, bowel, prostate, and liver, and accounts for a significant proportion of preventable cancers. Despite ample evidence of this relationship, public awareness is less clear. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we reviewed 32 studies examining lay awareness of alcohol as a risk factor for cancer in 16 countries...
April 2018: Cancer Epidemiology, Biomarkers & Prevention
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