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https://www.readbyqxmd.com/read/30341433/coffee-consumption-and-liver-related-hospitalizations-and-deaths-in-the-aric-study
#1
Emily A Hu, Mariana Lazo, Elizabeth Selvin, James P Hamilton, Morgan E Grams, Lyn M Steffen, Josef Coresh, Casey M Rebholz
BACKGROUND/OBJECTIVES: Coffee consumption has been found to be associated with reduced risk of chronic conditions such as liver disease. However, less is known about the association between coffee and liver-related hospitalizations and deaths. SUBJECTS/METHODS: We conducted a prospective analysis on 14,208 participants aged 45-64 years from the Atherosclerosis Risk in Communities (ARIC) study. Coffee consumption (cups/day) was assessed using food frequency questionnaires at visit 1 (1987-89) and visit 3 (1993-95)...
October 19, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/30340526/native-valve-endocarditis-due-to-escherichia-coli-infection-a-case-report-and-review-of-the-literature
#2
Nobuhiro Akuzawa, Masahiko Kurabayashi
BACKGROUND: Infective endocarditis due to Escherichia coli is a rare disease but is increasing in frequency, especially among older women. In addition, its mortality rate is higher than that of endocarditis due to the HACEK-group gram-negative bacteria (Haemophilus spp., Aggregatibacter spp., Cardiobacterium hominis, Eikenella corrodens, and Kingela spp.). CASE PRESENTATION: A 58-year-old Japanese woman with a history of alcohol abuse was admitted to our hospital because of a fever...
October 19, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/30336390/cannabis-use-during-alcohol-treatment-is-associated-with-alcohol-related-problems-one-year-post-treatment
#3
Meenakshi S Subbaraman, Jane Metrik, Deidre Patterson, Robert L Stout
BACKGROUND: Prior research shows that cannabis use during treatment for Alcohol Use Disorders (AUD) is related to fewer abstinent days from alcohol, although only among those who use cannabis 1-2x/month. Here we extend prior research by assessing the relationship between the frequency of cannabis use during AUD treatment and post-treatment alcohol-related consequences. METHODS: Data come from the Combined Pharmacotherapies and Behavioral Interventions (COMBINE) Study, a large US randomized control trial of treatments for AUD...
October 4, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/30336351/pka-pp1-and-dc1-phosphorylation-mediate-alcohol-induced-ciliary-dysfunction-in-chlamydomonas-reinhardtii
#4
Fan Yang, Chasity Scarbrough, Joseph H Sisson, Maureen Wirschell
Excessive alcohol consumption impairs mucociliary clearance, in part, by compromising ciliary movement. Our previous study found alcohol reduces ciliary beat frequency in Chlamydomonas through a mechanism that involves the β and γ heavy chains of the outer dynein arm (ODA). Moreover, we identified DC1, a subunit of the ODA-docking complex (ODA-DC), as the first ciliary target for alcohol. DC1 phosphorylation is alcohol sensitive and correlates with alcohol-induced ciliary dysfunction (AICD). Furthermore, DC1 phosphorylation is disrupted in the absence of the central pair and ODA...
May 9, 2018: Alcohol
https://www.readbyqxmd.com/read/30335780/effectiveness-of-motivational-interviewing-on-adult-behaviour-change-in-health-and-social-care-settings-a-systematic-review-of-reviews
#5
Helen Frost, Pauline Campbell, Margaret Maxwell, Ronan E O'Carroll, Stephan U Dombrowski, Brian Williams, Helen Cheyne, Emma Coles, Alex Pollock
BACKGROUND: The challenge of addressing unhealthy lifestyle choice is of global concern. Motivational Interviewing has been widely implemented to help people change their behaviour, but it is unclear for whom it is most beneficial. This overview aims to appraise and synthesise the review evidence for the effectiveness of Motivational Interviewing on health behaviour of adults in health and social care settings. METHODS: A systematic review of reviews. Methods were pre-specified and documented in a protocol (PROSPERO-CRD42016049278)...
2018: PloS One
https://www.readbyqxmd.com/read/30334965/exercise-as-an-intervention-for-patients-with-end-stage-liver-disease-systematic-review
#6
Cameron T Locklear, Pegah Golabi, Lynn Gerber, Zobair M Younossi
BACKGROUND: Various etiologies of chronic liver disease often result in cirrhosis. Beside obvious liver-related complications, cirrhosis also leads to loss of muscle mass and decreased exercise capacity. In this study, our aim was to conduct a systematic review of literature to investigate the efficacy of exercise interventions in patients with cirrhosis. METHOD: PubMed was used to perform the literature search. The mesh terms used were the following: (liver (and) cirrhosis (and) exercise or (exercise therapy))...
October 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30334685/homophobic-bullying-and-sexual-minority-youth-alcohol-use-do-sex-and-race-ethnicity-matter
#7
Amanda M Pollitt, Allen B Mallory, Jessica N Fish
PURPOSE: Sexual minority youth (SMY) are more likely to use alcohol than their heterosexual peers, yet a lack of research on within-group differences and modifiable mechanisms has hindered efforts to address alcohol use disparities. The purpose of the current study was to examine differences in the mediating role of homophobic bullying on the association between sexual orientation identity and drinking frequency and heavy episodic drinking frequency by sex and race/ethnicity. METHODS: We used data from a subsample of 20,744 youth in seven states from the 2015 Youth Risk Behavior Survey, a population-based data set of 9-12th grade high school students in the United States...
October 2018: LGBT Health
https://www.readbyqxmd.com/read/30328365/children-parental-alcohol-consumption-and-intimate-partner-violence-a-multicountry-analysis-by-perpetration-versus-victimization-and-sex
#8
Kathryn Graham, Sharon Bernards, Anne-Marie Laslett, Gerhard Gmel, Sandra Kuntsche, Sharon Wilsnack, Kim Bloomfield, Ulrike Grittner, Angela Taft, Ingrid Wilson, Samantha Wells
Both living with children and alcohol consumption are positively associated with intimate partner violence (IPV). We assessed their combined relationship with physical IPV (P-IPV) victimization and perpetration, and explored possible moderating roles of sex and culture. Data included 15 surveys of 13,716 men and 17,832 women in 14 countries from the GENACIS (Gender, Alcohol, and Culture: An International Study) collaboration. P-IPV was measured as victim of physical aggression by an intimate partner (Vic-Only), perpetrator of physical aggression toward a partner (Perp-Only), or both victim and perpetrator (i...
October 17, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/30326140/discussions-of-alcohol-use-in-an-online-social-network-for-smoking-cessation-analysis-of-topics-sentiment-and-social-network-centrality
#9
Amy M Cohn, Michael S Amato, Kang Zhao, Xi Wang, Sarah Cha, Jennifer L Pearson, George D Papandonatos, Amanda L Graham
BACKGROUND: Few Internet smoking cessation programs specifically address the impact of alcohol use during a quit attempt, despite its common role in relapse. This study used topic modeling to describe the most prevalent topics about alcohol in an online smoking cessation community, the prevalence of negative sentiment expressed about alcohol use in the context of a quit attempt (i.e., alcohol should be limited or avoided during a quit attempt) within topics, and the degree to which topics differed by user social connectivity within the network...
October 16, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/30326006/effect-of-gabapentin-vs-pregabalin-on-pain-intensity-in-adults-with-chronic-sciatica-a-randomized-clinical-trial
#10
Kelvin Robertson, Laurence A G Marshman, David Plummer, Elena Downs
Importance: Optimal pharmacologic treatment for chronic sciatica (CS) is currently unclear. While gabapentin (GBP) and pregabalin (PGB) are both used to treat CS, equipoise exists. Nevertheless, pharmaceutical regulation authorities typically subsidize one drug over the other. This hinders interchange wherever the favored drug is either ineffective or ill-tolerated. Objective: To assess GBP vs PGB head to head for the treatment of CS. Design, Setting, and Participants: A preplanned interim analysis of a randomized, double-blind, double-dummy crossover trial of PGB vs GBP for management of CS at half the estimated final sample size was performed in a single-center, tertiary referral public hospital...
October 15, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/30323909/association-between-diets-and-mild-cognitive-impairment-in-adults-aged-50-years-or-older
#11
Kyoung Yun Kim, Jung-Mi Yun
BACKGROUND/OBJECTIVE: As aging progresses, the number of patients with cognitive impairment also increases. Cognitive function is not generally correlated with diet, and there is debate over that association. Thus, the present study aimed to investigate the association between dietary intake and cognitive function among adults aged 50 years or older. SUBJECTS/METHODS: Between July 2017 and March 2018, 324 adults aged over 50 years from Gwangju Sun-Han hospital participated in a dietary survey...
October 2018: Nutrition Research and Practice
https://www.readbyqxmd.com/read/30323183/decreases-in-global-beer-supply-due-to-extreme-drought-and-heat
#12
Wei Xie, Wei Xiong, Jie Pan, Tariq Ali, Qi Cui, Dabo Guan, Jing Meng, Nathaniel D Mueller, Erda Lin, Steven J Davis
Beer is the most popular alcoholic beverage in the world by volume consumed, and yields of its main ingredient, barley, decline sharply in periods of extreme drought and heat. Although the frequency and severity of drought and heat extremes increase substantially in range of future climate scenarios by five Earth System Models, the vulnerability of beer supply to such extremes has never been assessed. We couple a process-based crop model (decision support system for agrotechnology transfer) and a global economic model (Global Trade Analysis Project model) to evaluate the effects of concurrent drought and heat extremes projected under a range of future climate scenarios...
October 15, 2018: Nature Plants
https://www.readbyqxmd.com/read/30322212/addressing-opioid-related-chemical-coping-in-long-term-opioid-therapy-for-chronic-noncancer-pain-a-multicenter-observational-cross-sectional-study
#13
Anyela Marcela Castañeda, Chang-Soon Lee, Yong-Chul Kim, Dasom Lee, Jee Youn Moon
Opioid consumption has increased worldwide, which carries the risk of opioid use disorder (OUD). However, the literature on OUD and opioid-related chemical coping (OrCC) in chronic noncancer pain (CNCP) is heterogeneous, with most studies conducted in the United States. We performed a multicenter, observational, cross-sectional study to address OrCC in long-term opioid therapy (LtOT) for CNCP in South Korea. The objectives were to determine the frequency and predictors of OrCC. We included 258 patients. Among them, fifty-five (21%) patients showed OrCC...
October 14, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/30321740/a-longitudinal-investigation-of-the-association-between-cannabis-use-and-alcohol-use-among-people-living-with-hiv
#14
Jeffrey D Wardell, Paul A Shuper, Christian S Hendershot
BACKGROUND: Both cannabis use and alcohol use are elevated among people living with HIV, but few studies have investigated the relationship between cannabis use and alcohol use in this population. This study examined the longitudinal association between cannabis use and alcohol use among people living with HIV and explored the moderating role of medicinal vs. recreational cannabis use. METHOD: Participants were cannabis users (N=763) enrolled in the Ontario HIV Treatment Network Cohort Study (67% White, 88% male, 68% gay, median income in the $40,000-$50,000 range)...
October 6, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/30321649/reproductive-and-developmental-f1-toxicity-following-exposure-of-pubescent-f0-male-mice-to-bisphenol-a-alone-and-in-a-combination-with-x-rays-irradiation
#15
Małgorzata M Dobrzyńska, Aneta Gajowik, Ewa A Jankowska-Steifer, Joanna Radzikowska, Ewa J Tyrkiel
Exposure to environmental toxicants may affect reproduction and development of subsequent generations. This study was aimed at determining the male-mediated F1 effects induced following 8-weeks of subchronic exposure of F0 male mice to bisphenol A (BPA) alone and in a combination with X-rays irradiation (IR) started during their puberty. 4.5 weeks old F0 male mice were exposed to BPA dissolved in ethyl alcohol and diluted in drinking water at the following doses: 5 mg/kg bw, 10 mg/kg bw, 20 mg/kg bw or irradiated with X-rays (0...
October 12, 2018: Toxicology
https://www.readbyqxmd.com/read/30319556/isolation-development-and-genomic-analysis-of-bacillus-megaterium-sr7-for-growth-and-metabolite-production-under-supercritical-carbon-dioxide
#16
Adam J E Freedman, Kyle C Peet, Jason T Boock, Kevin Penn, Kristala L J Prather, Janelle R Thompson
Supercritical carbon dioxide (scCO2 ) is an attractive substitute for conventional organic solvents due to its unique transport and thermodynamic properties, its renewability and labile nature, and its high solubility for compounds such as alcohols, ketones, and aldehydes. However, biological systems that use scCO2 are mainly limited to in vitro processes due to its strong inhibition of cell viability and growth. To solve this problem, we used a bioprospecting approach to isolate a microbial strain with the natural ability to grow while exposed to scCO2 ...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/30315827/the-global-prevalence-and-genetic-spectrum-of-lysosomal-acid-lipase-deficiency-a-rare-condition-that-mimics-nafld
#17
Anna Carter, Simon Mark Brackley, Jiali Gao, Jake Peter Mann
BACKGROUND & AIMS: Lysosomal acid lipase deficiency (LAL-D) is an autosomal recessive condition that may present in a mild form (cholesteryl ester storage disease (CESD)), which mimics non-alcoholic fatty liver disease (NAFLD). It has been suggested that CESD may affect 1 in 40,000 and is under-diagnosed in NAFLD clinics. Therefore, we aimed to estimate the prevalence of LAL-D using analysis of genetic variation in LIPA. METHODS: MEDLINE and EMBASE were systematically searched for previously reported disease variants and prevalence estimates...
October 10, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/30312202/alcohol-use-thresholds-for-identifying-alcohol-related-problems-before-and-following-roux-en-y-gastric-bypass
#18
Gretchen E White, Anita P Courcoulas, Gale A Richardson, Christina Mair, Wendy C King
OBJECTIVE: The aim of this study was to determine the sensitivity and specificity of potential thresholds of alcohol use for identifying alcohol-related problems in women post-Roux-en-Y gastric bypass (RYGB). BACKGROUND: Despite evidence that RYGB alters alcohol pharmacokinetics and is associated with an increased risk for alcohol-related problems, the level of alcohol use that should prompt further screening for alcohol-related problems following RYGB is unclear...
October 11, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/30311281/the-interactive-effects-of-perceived-peer-drinking-and-personality-profiles-on-adolescent-drinking-a-prospective-cohort-study
#19
Nina Pocuca, Leanne Hides, Catherine A Quinn, Melanie J White, Louise Mewton, Nicola Clare Newton, Tim Slade, Cath Chapman, Gavin Andrews, Maree Teesson, Steve Allsop, Nyanda McBride
AIMS: (1) To classify Australian adolescents according to their alcohol consumption trajectories; and (2) to assess the direct and interactive effects of perceived peer drinking (PPD) and personality on adolescent drinking. DESIGN: Prospective cohort study comprising secondary analysis of six waves of prospective data (collected between 2014 and 2016) from the control arm of the Climate Schools Combined Study. SETTING: Nineteen schools across three Australian states...
October 12, 2018: Addiction
https://www.readbyqxmd.com/read/30309046/examining-associations-between-body-mass-index-in-18%C3%A2-25-year-olds-and-energy-intake-from-alcohol-findings-from-the-health-survey-for-england-and-the-scottish-health-survey
#20
Viviana Albani, Jennifer Bradley, Wendy L Wrieden, Stephanie Scott, Cassey Muir, Christine Power, Niamh Fitzgerald, Martine Stead, Eileen Kaner, Ashley J Adamson
Evidence on the relationship between alcohol consumption and body mass index (BMI) is mixed, particularly for young adults. This study explored the relationship between energy obtained from alcoholic beverages and BMI using data for 18⁻25 year-olds ( n = 7691) from pooled cross-sections of the 2008⁻2014 Health Survey for England and the Scottish Health Survey. Energy obtained from alcoholic beverages (excluding mixers) on the heaviest drinking day in the past week was expressed as percentage of total recommended dietary allowance (RDA) of energy (% RDA Energy)...
October 10, 2018: Nutrients
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