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Aged 80 and older

Jillian Hurd, Andrea Pike, John Knight, Gary Tarrant, Kris Aubrey-Bassler, Shabnam Asghari, Marshall Godwin
OBJECTIVE: To develop a better understanding of the current health status and health care use of the population of very elderly Newfoundlanders to inform policy makers, decision makers, and health care providers about aspects of the health care system that might be in higher demand in the near future. DESIGN: Descriptive analysis using data from the Newfoundland and Labrador component of the Canadian Primary Care Sentinel Surveillance Network database for the 2013 calendar year...
October 2018: Canadian Family Physician Médecin de Famille Canadien
Carolyn J Gibson, Yixia Li, Sabra S Inslicht, Karen H Seal, Amy L Byers
OBJECTIVES: To examine relationships between posttraumatic stress disorder (PTSD), diabetes, and cardiovascular disease (CVD) among older men and women. METHODS: In a national retrospective cohort study of Veterans aged ≥55 (n=2,789,264, 6% female), associations between PTSD and diabetes (2008-2011) and incident CVD (2012-2015) were assessed with gender-stratified Fine-Gray proportional hazard models, adjusted for demographics and medical comorbidities. RESULTS: Incident CVD was observed in 22% of men and 12% of women, and related to PTSD (men HR=1...
September 25, 2018: American Journal of Geriatric Psychiatry
Thiago Veiga Jardim, Miles D Witham, Shafika Abrahams-Gessel, F Xavier Gómez-Olivé, Stephen Tollman, Lisa Berkman, Thomas A Gaziano
OBJECTIVES: To characterize the cardiovascular disease (CVD) profile of individuals aged 80 and older in rural South Africa. DESIGN: First wave of population-based longitudinal cohort. SETTING: Agincourt subdistrict (Mpumalanga Province) in rural South Africa. PARTICIPANTS: Adults residents (N = 5,059). MEASUREMENTS: In-person interviews were conducted to obtain social, behavioral, economic, and clinical data...
October 12, 2018: Journal of the American Geriatrics Society
Bjørn Heine Strand, Astrid Bergland, Lone Jørgensen, Henrik Schirmer, Nina Emaus, Rachel Cooper
Background: Evidence pertaining to whether more recent born generations of adults reaching old age have better physical capability than previous generations is scarce and inconclusive. We aimed to investigate birth cohort differences in grip strength. Methods: The study comprised 5,595 individuals from the Tromsø study waves in 1994/1995, 2007/2008, and 2015/2016. Grip strength (bar) was measured using a Martin vigorimeter, and compared across three birth cohorts of 66- to 84-year-olds (born in: 1910-1929, 1923-1942, 1931-1949), as well as within narrower age bands to ensure nonoverlapping cohorts...
October 11, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Ka-Keung Yam, Yat-Fung Shea, Tuen-Ching Chan, Ka-Chun Chiu, James Ka-Hei Luk, Leung-Wing Chu, Felix Hon-Wai Chan
AIM: To study the prevalence and risk factors of delirium and subsyndromal delirium (SSD) in Chinese older adults with acute medical illnesses. METHODS: A prospective cohort study was carried out in acute general medical wards in a university-affiliated hospital in Hong Kong. Patients were assessed by the confusion assessment method by geriatricians within 6 h after admission and classified into three mutually exclusive groups, namely delirium, SSD and those without both conditions...
October 12, 2018: Geriatrics & Gerontology International
Takashi Yamauchi, Suguru Kubota, Kosei Hasegawa, Hideki Ueda
Thoracic endovascular aortic repair (TEVAR) is expected to be minimally invasive, especially in older patients. However, clinical results of TEVAR in octogenarians including medical costs are limited. Between 2010 and 2016, a total of 57 patients over 80 years of age (mean age 84.1 ± 3.4 years) underwent TEVAR at our hospital. The proximal landing zone (PLZ) was zone 0 in 7 patients (12.3%), zone 1 in 10 patients (17.5%), zone 2 in 9 patients (15.8%), zone 3 in 13 patients (22.8%), and zone 4 in 18 patients (31...
October 11, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
Naoko Sagawa, Zachary A Marcum, Robert M Boudreau, Joseph T Hanlon, Steven M Albert, Celia O'Hare, Suzanne Satterfield, Ann V Schwartz, Aaron I Vinik, Jane A Cauley, Tamara B Harris, Anne B Newman, Elsa S Strotmeyer
Fall injuries cause morbidity and mortality in older adults. We assessed if low blood pressure (BP) is associated with fall injuries, including sensitivity analyses stratified by antihypertensive medications, in community-dwelling adults from the Health, Aging and Body Composition Study ( N  = 1819; age 76.6 ± 2.9 years; 53% women; 37% black). Incident fall injuries ( N  = 570 in 3.8 ± 2.4 years) were the first Medicare claims event from clinic visit (7/00-6/01) to 12/31/08 with an ICD-9 fall code and non-fracture injury code, or fracture code with/without a fall code...
September 2018: European Journal of Ageing
Gabriel Levin, Amihai Rottenstreich, Yishay Weill, Raphael N Pollack
OBJECTIVE: Numerous studies have evaluated the factors associated with ECV success. Yet, bladder volume has never been examined. We hypothesize that maternal bladder volume may affect ECV success rate. We aim to evaluate the role of maternal bladder volume during external cephalic version (ECV) on the procedure success rates. STUDY DESIGN: We reviewed prospective collected data of all patients who underwent ECV at our center during 2001-2012. The study group included 100 patients that underwent ECV with bladder volume below 400 ml...
October 2, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Andrew M Briggs, Islene Araujo de Carvalho
BACKGROUND: Integrated care is recognised as an important enabler to healthy ageing, yet few countries have managed to sustainably deliver integrated care for older people. We aimed to gather global consensus on the key actions required to realign health and long-term systems and integrate services to implement the World Health Organization (WHO) Integrated Care for Older People (ICOPE) approach. METHODS: A two-round eDelphi study, including a global consultation meeting, was undertaken to identify, refine and generate consensus on the actions required across high-, middle- and low-income countries to implement the WHO ICOPE approach...
2018: PloS One
William L Hwang, Rachel L Wolfson, Andrzej Niemierko, Karen J Marcus, Steven G DuBois, Daphne Haas-Kogan
Background: Neuroblastoma is the most common pediatric extracranial solid tumor. Within conventional risk groups, there is considerable heterogeneity in outcomes, indicating the need for improved risk stratification. Methods: In this study we analyzed the somatic mutational burden of 515 primary, untreated neuroblastoma tumors from three independent cohorts. Mutations in coding regions were determined by whole-exome/genome sequencing of tumor samples compared to matched blood leukocytes...
October 10, 2018: Journal of the National Cancer Institute
Echo L Warner, Laura Martel, Judy Y Ou, Gina E Nam, Sara Carbajal-Salisbury, Virginia Fuentes, Anne C Kirchhoff, Deanna Kepka
In the United States, Latinos are more likely to be uninsured and diagnosed with later stage cancer than non-Hispanic whites. Promotoras (lay health educators) help improve cancer knowledge and facilitate access to cancer screenings. We tested a promotora led workplace-based intervention to improve knowledge of and adherence to breast, cervical, and colorectal cancer screening among Latino employees in service or manual labor jobs. Latinos 18 and older from Salt Lake County, Utah were enrolled from January 2015 to February 2016...
October 10, 2018: Journal of Community Health
Dexia Kong, Mengting Li, Yin-Ling Irene Wong, Jinjiao Wang, Benjamin C Sun, Xinqi Dong
Older adults visit emergency departments (EDs) at a disproportionally higher rate than other age groups. Prior studies examining racial disparities in ED utilization focus on African Americans and Hispanics. There is a dearth of information on ED utilization patterns among older Asian Americans despite the evidence that ED expenditures in Asian Americans are comparable to that of Caucasians. To address this knowledge gap, we examined factors associated with ED service utilization in the largest Asian subgroup, U...
October 9, 2018: Journal of Immigrant and Minority Health
Takehiko Sugita, Naohisa Miyatake, Toshimi Aizawa, Akira Sasaki, Masayuki Kamimura, Atsushi Takahashi
PURPOSE: Although many studies have been performed to evaluate the quality of life (QOL) and patient satisfaction after total knee arthroplasty (TKA), almost all evaluations were performed in patients after unilateral TKA or in patients after mixed unilateral and bilateral TKA. Accordingly, this study aimed to evaluate QOL after staged bilateral TKA. METHODS: A total of 78 patients who underwent staged bilateral TKA for varus knee osteoarthritis were included in this study...
October 10, 2018: International Orthopaedics
Daiva Nevidomskyte, Gale L Tang, Susanna H Shin, Thomas S Hatsukami, Sara Khor, David R Flum, Mark H Meissner, Sherene Shalhub
BACKGROUND: The benefit for carotid endarterectomy (CEA) to prevent a potential stroke has been shown to be less beneficial for women compared with men and the risk of carotid stenting (CAS) is higher in women than men. We hypothesized that a community-based Washington state registry data would also reveal increased morbidity and mortality for women undergoing carotid interventions. METHODS: Deidentified data for CEA and CAS between 2010 and 2015 were obtained from 19 hospitals participating in the Washington State Vascular-Interventional Surgical Care and Outcomes Assessment Program...
October 6, 2018: Journal of Vascular Surgery
Ji Young Chang, Sung-Ae Jung, Chang Mo Moon, Seong-Eun Kim, Hye-Kyung Jung, Ki-Nam Shim
Background/Aims: Testing for hepatitis B virus (HBV) serologic markers and appropriate vaccination are required in the management of inflammatory bowel disease (IBD) patients. We evaluated immunogenicity for HBV in IBD patients and the response to the HBV vaccination. Methods: From May 2014 to August 2016, patients diagnosed with IBD were prospectively included and evaluated for anti-HBs antibody, anti-HBc antibody, and HBs antigen. Among the 73 patients who were confirmed with nonimmunity to HBV, 44 patients who had completed the 3-dose HBV vaccination series received a single booster vaccination, while 29 patients who had not completed the vaccinations series or were unsure of receiving the vaccination received a full vaccination series...
October 10, 2018: Intestinal Research
Catherine A Ammerman, Brent A Simpkins, Nora Warman, Tara N Downs
OBJECTIVES: To compare the effects of a Geriatric Patient-Aligned Care Team (GeriPACT) on deprescribing of potentially inappropriate medications (PIMs) in individuals aged 80 and older with usual care (UC) in the Veterans Affairs setting. DESIGN: Retrospective cohort study. SETTING: Veterans Affairs Medical Center in Lexington, Kentucky. PARTICIPANTS: Individuals aged 80 and older who filled a PIM at least 90 days before a GeriPACT or primary care appointment between January 1, 2015, and September 6, 2017 (N = 568)...
October 9, 2018: Journal of the American Geriatrics Society
Penpak Noopud, Areerat Suputtitada, Surasa Khongprasert, Vijit Kanungsukkasem
BACKGROUND: Previous research indicates that dance training may improve balance among older adults. AIMS: This study investigated the effects of Thai traditional dance on balance performance among older women. METHODS: Forty-three women aged 60-80 years, with mean scores between 45 and 52 points on the Berg Balance Scale (BBS), were recruited and randomly assigned into two groups: a Thai traditional dance group (TTDG) (n = 22) and a control group (CG) (n = 21)...
October 8, 2018: Aging Clinical and Experimental Research
Patricia A Cronin, Anya Romanoff, Emily C Zabor, Michelle Stempel, Anne Eaton, Lillian M Smyth, Alice Y Ho, Monica Morrow, Mahmoud El-Tamer, Mary L Gemignani
BACKGROUND: Low incidence of breast cancer in men (BCM) (< 1% of all breast cancers) has led to a paucity of outcome data. This study evaluated the impact of age on BCM outcomes. METHODS: For this study, BCM patients treated between 2000 and 2011 were stratified by age (≤ 65 or > 65 years). Kaplan-Meier methods were used to compare overall survival (OS) and breast cancer-specific survival (BCSS). Competing-risk methods analyzed time to second primary cancers (SPCs), with any-cause death treated as a competing risk...
October 8, 2018: Annals of Surgical Oncology
Lisa Calvocoressi, Edward Uchio, John Ko, Krishnan Radhakrishnan, Mihaela Aslan, John Concato
Older men are more likely to have advanced prostate cancer at time of their diagnosis, but whether prostate tumors are inherently (biologically) more aggressive with advancing age is uncertain. To address this gap in knowledge, we analyzed data from veterans (n=971) diagnosed with prostate cancer during 1991-1995. Factors included age, detection of prostate cancer by screening, prostate-specific antigen (PSA) level, anatomic stage, and Gleason score. Information on molecular markers obtained from immunohistochemical staining of prostate tissue, included B cell lymphoma-2 (bcl-2), p53, and microvessel density (MVD), each having a previously documented association with disease progression and increased risk of prostate cancer death...
October 7, 2018: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
Allison Navis, Rocio Garcia-Santibanez, Maryna Skliut
BACKGROUND: Rate of ischemic strokes and transient ischemic attacks (TIAs) increases with age. There is lack of evidence on how age affects treatment strategies and outcomes. Our aim is to compare epidemiology of ischemic strokes and TIAs in adult and geriatric populations including risk factors, treatment delivered, and outcomes. DESIGN: We designed a retrospective cross-sectional review of patients admitted to neurology with diagnosis of stroke or TIA from 2010 to 2015...
October 6, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
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