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Digital rectal examination

Ersin Koseoglu, Altug Tuncel, Melih Balci, Oguzhan Kaya, Yilmaz Aslan, Ozer Guzel, Fatma Meric Yilmaz, Ali Atan
Objectives: To investigate serum and urine levels of Alpha-methylacyl-CoA-racemase (AMACR) and Netrin 1 in patients with and without prostate cancer and to determine whether these markers could be used as alternatives in diagnosis of prostate cancer instead of serum prostate specific antigen (PSA) levels. Methods: One hundred and seventy five patients between 45-75 years to whom transrectal ultrasound guided biopsies were performed for abnormal serum PSA levels or digital rectal examinations were included...
June 30, 2018: Colombia Médica: CM
Bo-Ren Wang, Cheng Che Chen, Ren-Hao Zheng, Ju-Chuan Hu, Yen-Chuan Ou
BACKGROUND: Although prostate biopsy is an accepted option for cancer detection, there is little data regarding the clinical outcome of 18-core transrectal ultrasound (TRUS)-guided biopsy. This retrospective study compared cancer detection rates and biopsy complications between 12- and 18-core TRUS biopsy in Asian patients with prostate-specific antigen (PSA) levels between 4.0 and 20.0 ng/mL. METHODS: In total, 1120 consecutive patients with PSA levels between 4...
August 9, 2018: Journal of the Chinese Medical Association: JCMA
Samuel W D Merriel, Garth Funston, Willie Hamilton
Prostate cancer is a common malignancy seen worldwide. The incidence has risen in recent decades, mainly fuelled by more widespread use of prostate-specific antigen (PSA) testing, although prostate cancer mortality rates have remained relatively static over that time period. A man's risk of prostate cancer is affected by his age and family history of the disease. Men with prostate cancer generally present symptomatically in primary care settings, although some diagnoses are made in asymptomatic men undergoing opportunistic PSA screening...
August 10, 2018: Advances in Therapy
Yu-Chen Chen, Hao-Wei Chen, Shu-Pin Huang, Hsin-Chin Yeh, Ching-Chia Li
OBJECTIVES: Previous studies have compared infectious outcomes on the basis of whether rectal preparation was performed; however, they failed to evaluate the quality of each rectal preparation, which may have led to confounding results. This study aimed to compare hospitalizations for urosepsis within 1 month after transrectal ultrasound-guided prostate biopsy between patients with adequate and traditional rectal preparations. MATERIALS AND METHODS: Between January 2011 and December 2016, a total of 510 patients who underwent transrectal ultrasound - guided prostate biopsy at our institutions and were orally administered prophylactic antibiotics (levofloxacin) were included...
August 5, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
James Chi-Yong Ngu, Li-Jen Kuo, Ching-Huei Kung, Chi-Long Chen, Chia-Chun Kuo, Sheng-Wei Chang, Chia-Che Chen
BACKGROUND: Full-thickness local excision (FTLE) for rectal cancer showing clinical complete remission (cCR) after neoadjuvant chemoradiation therapy (NCRT) is associated with good oncological results. The purpose of this study was to report the results of robotic transanal minimally invasive surgery for such patients. METHODS: Patients were treated with a 5-fluorouracil-based NCRT regimen. The determination of cCR was based on digital rectal examination, colonoscopy, and magnetic resonance imaging...
August 2, 2018: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
Marko Simunovic, Vanja Grubac, Kevin Zbuk, Raimond Wong, Angela Coates
BACKGROUND: Patients with rectal cancer in whom the mesorectal fascia is threatened by tumour are more likely than all patients with stage II/III disease to benefit from preoperative radiotherapy (RT). The objective of this study was to assess whether the status of the mesorectal fascia versus a stage II/III designation can best inform the use of preoperative RT in patients undergoing major rectal cancer resection. METHODS: We reviewed the charts of consecutive patients with primary rectal cancer treated by a single surgeon at McMaster University, Hamilton, Ontario, between March 2006 and December 2012...
August 1, 2018: Canadian Journal of Surgery. Journal Canadien de Chirurgie
Mehrzad Lotfi, Reza Beheshti, Mohammad Reza Rouhezamin, Abbas Rezaianzadeh, Pouya Farhadi, Zeinab Daneshi
Background: Prostate cancer is the most common malignancy among the male population in the United States and the 3rd most common non-skin cancer among men in Iran. Its prevalence has shown a rising trend in recent decades. The aim of this study was to report the epidemiological features of prostate cancer in patients referred for prostate biopsy in the south of Iran and to evaluate the accuracy of the levels of the prostate-specific antigen (PSA) and the PSA-density (PSAD) as well as the extension of the disease in the prediction of the biological behavior of prostate cancer...
July 2018: Iranian Journal of Medical Sciences
Ki H Kim, Sang W Kim, Hee S Son, Dae K Kim, Dae C Jung, Hyun W Kim, Joon C Kim, Sung J Hong, Jang H Kim
BACKGROUND: Even though the safety of the treatment for prostate cancer diagnosed by HoLEP has been reported, the diagnostic value of HoLEP for prostate cancer detection has not been confirmed. Therefore, we investigated the diagnostic potential of HoLEP for detecting prostate cancer. METHODS: Between December 2009 and October 2015, 359 patients (median age, 70.9 years; range, 66.2-74.8) were treated simultaneously with HoLEP and transrectal prostate needle biopsy (TPNB)...
July 23, 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
Satyendra Persaud, William D Aiken
Objectives: To examine the attitudes, beliefs and practices of Caribbean urologists regarding prostate-specific antigen (PSA)-based screening in the Caribbean region particularly as it relates to Afro-Caribbean men. Design: An Internet-based descriptive cross-sectional study using a standardised questionnaire designed to capture information on respondents' attitudes, beliefs and practices towards PSA-based screening was conducted using the online survey tool Survey Monkey among known urologists in the Caribbean, based on the complete mailing list of the membership of the Caribbean Urological Association...
2018: Ecancermedicalscience
Osama Aa Elhardello, John MacFie
No abstract text is available yet for this article.
July 20, 2018: Emergency Medicine Journal: EMJ
Mansoor Khan
No abstract text is available yet for this article.
July 20, 2018: Emergency Medicine Journal: EMJ
Wan Song, Ji Woong Yu, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee, Han Yong Choi, Eun-Suk Kang, Hwang Gyun Jeon
Purpose: To investigate the clinical usefulness of natural killer cell activity (NKA) for detection of prostate cancer (PCa) and prediction of Gleason grade. Patients and methods: We prospectively enrolled 221 patients who underwent transrectal ultrasound-guided prostate biopsy for suspected PCa due to elevated prostate-specific antigen (PSA) >2.5 ng/mL or abnormal findings on digital rectal examination (n=146), or who were diagnosed with PCa (n=75) between 2016 and 2017...
2018: OncoTargets and Therapy
Christopher J Black, Alexander C Ford
Chronic idiopathic constipation (CIC) is one of the most common gastrointestinal disorders, with a global prevalence of 14%. It is commoner in women and its prevalence increases with age. There are three subtypes of CIC: dyssynergic defaecation, slow transit constipation and normal transit constipation, which is the most common subtype. Clinical assessment of the patient with constipation requires careful history taking, in order to identify any red flag symptoms that would necessitate further investigation with colonoscopy to exclude colorectal malignancy...
July 16, 2018: Medical Journal of Australia
Alejandro Granados, Naomi Low-Beer, Jenny Higham, Roger Kneebone, Fernando Bello
OBJECTIVE: Motivated by the fact that palpation skills are challenging to learn and teach, particularly during Digital Rectal Examinations (DRE), and the lack of understanding of what constitutes adequate performance, we present a visualisation and analysis system that uses small position and pressure sensors located on the examining finger, allowing the quantitative analysis of duration, steps and pressure applied. METHODS: The system is first described, followed by an experimental study of twenty experts from four clinical specialties performing ten DREs each on a benchtop model using the proposed system...
March 28, 2018: IEEE Transactions on Bio-medical Engineering
Julia Carrasco, Enrique Gómez, José Horacio García, José Valero, Alvaro Sánchez, Juan José Salamanca, Juan Pablo Campos, María José Requena
OBJECTIVES: Primary: to assess the use of simulators in prostate digital rectal examination and bladder catheterization on mental workload and the level of confidence in medical students. Secondary: to analyze student satisfaction and skills acquired by students with simulators. METHODS: We conducted a prospective, randomized study on medical students. Participants were divided into two groups: Group 1 (G1) (only the explanation) and group 2 (G2) (explanation + simulator workshop)...
July 2018: Archivos Españoles de Urología
Patricia Briar Neumann, Michael O'Callaghan
PURPOSE: The efficacy of pelvic floor muscle training (PFMT) for men with postprostatectomy incontinence (PPI) after robotic-assisted radical prostatectomy (RARP) is controversial and the mechanism for its possible effect remains unclear. The aim of this study was to investigate the relationship between bladder neck (BN) displacement, as a proxy for puborectal muscle activation, and continence outcomes after RARP. METHODS: Data were extracted from the South Australian Prostate Cancer Clinical Outcomes Collaborative database for men undergoing RARP by high volume surgeons who attended preoperative pelvic floor physiotherapy for pelvic floor muscle (PFM) training between 2012 and 2015...
June 2018: International Neurourology Journal
Leonardo Alfonso Bustamante-Lopez, Caio Sergio Rizkallah Nahas, Sergio Carlos Nahas, Carlos Frederico Sparapan Marques, Rodrigo Ambar Pinto, Guilherme Cutait Cotti, Antonio Rocco Imperiale, Evandro Sobroza de Mello, Ulysses Ribeiro, Ivan Cecconello
Studies have suggested that the use of neoadjuvant chemoradiation results in a lower lymph nodes yield in rectal cancer patients. OBJECTIVE: To evaluate factors associated with less than 12 lymph nodes harvested on patients with rectal cancer treated with preoperative chemoradiotherapy followed by total mesorectal excision. PATIENTS: This was a cohort/retrospective single cancer center study. Low and mid locally advanced rectal cancer or T2N0 under risk of sphincter resection underwent chemoradiotherapy followed by total mesorectal excision with curative intent...
July 5, 2018: International Journal of Surgery
Francesca Kum, Adam Jones, Raj Nigam
INTRODUCTION: Multi-parametric MRI (MP-MRI) prior to prostate biopsy is the investigation of choice for an elevated age-related PSA and abnormal digital rectal examination. MP-MRI in combination with transperineal template mapping biopsy has facilitated the development of the concept of targeted biopsies, either cognitively or with software fusion. Urinary retention is a recognised complication of transperineal prostate biopsy, with reported incidence being 1.6-11.4%. We present patient and procedure-related factors, which influence occurrence of urinary retention after transperineal template biopsy...
July 4, 2018: World Journal of Urology
Xiuying Shi, Chuifeng Fan
BACKGROUND: Hemorrhoid is a common anorectal disease. Hemorrhoids accompanied by endometriosis are unusual. As endometriosis in the rectum may mimic many other diseases, including cancer and inflammation, its diagnosis may be difficult, especially when it is combined with other diseases. CASE PRESENTATION: Here, we present a rare case of a patient with hemorrhoids accompanied by endometriosis in the rectum. The endometriosis mass was detected by digital rectal examination and CT scan and confirmed by pathological examination...
July 4, 2018: BMC Women's Health
Cheryl L Holt, Erin K Tagai, Sherie Lou Zara Santos, Mary Ann Scheirer, Janice Bowie, Muhiuddin Haider, Jimmie Slade
Project HEAL (Health through Early Awareness and Learning) is an implementation trial that compared two methods of training lay peer community health advisors (CHAs)-in-person ("Traditional") versus web-based ("Technology")-to conduct a series of three evidence-based cancer educational workshops in African American churches. This analysis reports on participant outcomes from Project HEAL. Fifteen churches were randomized to the two CHA training methods and the intervention impact was examined over 24 months...
June 28, 2018: Translational Behavioral Medicine
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