Read by QxMD icon Read

diagnostic or prognostic meta analysis

Ramon Nazareno Menezes Andrade, Walbert de Andrade Vieira, Ítalo de Macedo Bernardino, Ademir Franco, Luiz Renato Paranhos
OBJECTIVE: This study aimed to assess the validity of palatal rugoscopy for sexual dimorphism in the casework routine of forensic dentistry. DESIGN: A systematic literature reviews was established following the Preferred Reporting Items for Systematic reviews and Meta-analyses (PRISMA) and Cochrane guidelines. Six electronic databases were searched as the primary source of information. "Grey literature" was included to avoid selection and publication bias...
October 11, 2018: Archives of Oral Biology
Salman Guraya
BACKGROUND: Literature has shown that aberrantly expressed microRNAs may have implications in certain cancers. A wealth of studies signal potential prognostic role of microRNA-21 in GIT cancers. This meta-analysis quantitatively determines prognostic significance of circulating microRNA-21 in esophageal squamous cell carcinoma (ESCC), pancreatic ductal adenocarcinoma (PDAC) and colorectal carcinoma (CRC). METHODS: Databases of Medline, Wiley online library, Cochrane library, Taylor and Francis Online, CINAHL, Springer, Proquest, ISI Web of knowledge, ScienceDirect, and Emerald were searched using MeSH terms serum/tissue microRNA-21, prognosis, esophagus squamous cell carcinoma, pancreatic ductal adenocarcinoma, colorectal cancer...
October 15, 2018: International Journal of Surgery
Stanley J Huey, Jacqueline L Tilley
OBJECTIVE: Evidence demonstrating treatment efficacy for ethnic minorities has grown in recent years; however, Asian Americans (i.e., of East Asian or Southeast Asian heritage) are mostly excluded from recent reviews. In this review we (a) synthesize the literature on mental health treatment effects for Asian Americans and (b) evaluate support for competing theoretical perspectives on cultural tailoring. METHOD: A literature search supplemented with other search strategies identified 21 randomized trials of mental health interventions for Asian Americans (n = 6,377 total participants)...
November 2018: Journal of Consulting and Clinical Psychology
Minghui Shen, Ya Gao, Xueni Ma, Bo Wang, Jiarui Wu, Jiancheng Wang, Jipin Li, Jinhui Tian, Junhai Jia
BACKGROUND: Endometriosis is a major cause of disability and compromised the quality of life in women and teenage girls. The gold standard for diagnosis of endometriosis is laparoscopy with histology of excised endometriosis lesions. However, women can suffer for 8 to 12 years before obtaining a correct diagnosis. Several biomarkers showed good diagnostic value for endometriosis, but no studies directly or indirectly compare the diagnostic value of different biomarkers. We perform this network meta-analysis (NMA) to assess the diagnostic accuracy of hormonal biomarkers, and to find a most effective hormonal biomarker for the diagnosis of endometriosis...
October 2018: Medicine (Baltimore)
Qun Zheng, Zi-Xian Chen, Meng-Bei Xu, Xiao-Li Zhou, Yue-Yue Huang, Guo-Qing Zheng, Yan Wang
To achieve sufficient blood-brain barrier (BBB), penetration is one of the biggest challenges in the development of diagnostic and therapeutic for central nervous system (CNS) disorders. Here, we conducted a systematic review and meta-analysis to assess the preclinical evidence and possible mechanisms of borneol for improving co-administration of CNS drug delivery in animal models. The electronic literature search was conducted in six databases. Fifty-eight studies with 63 comparisons involved 1137 animals were included...
November 2018: Drug Delivery
Zhengtao Liu, Shuheng Liang, Shuping Que, Lin Zhou, Shusen Zheng, Adil Mardinoglu
Previous studies revealed the potential significance of circulating adiponectin levels with respect to the diagnosis and prediction of metabolic syndrome, but uncertainty has been noted across different cohorts. Systematic evaluation was performed for diagnostic accuracy and predictivity of adiponectin variation for metabolic syndrome in enrolled studies including 1,248 and 6,020 subjects, respectively. Adiponectin can identify metabolic syndrome with moderate accuracy (area under the curve = 0.81, 95% CI: 0...
2018: Frontiers in Physiology
Shui-Ping Dai, Jing Jin, Wei-Min Li
The detection of long non-coding RNA (lncRNA) is a novel method for lung cancer diagnosis. However, the diagnostic efficacy of lncRNA in different studies is inconsistent. Therefore, we conducted this meta-analysis to elucidate the diagnostic efficacy of lncRNA in identification of lung cancer including small cell lung cancer. The online PubMed, Medline, EMBASE, CNKI and Wanfang literature databases were searched to identify all related articles about the diagnostic efficacy of lncRNA for lung cancer. 28 articles including 3044 patients with lung cancer and 2598 controls were enrolled in our meta-analysis...
October 17, 2018: Postgraduate Medical Journal
Niveditha Devasenapathy, Ralph Maddison, Rajesh Malhotra, Sanjay Zodepy, Saket Sharma, Daniel L Belavy
Background: One-third of individuals report limitations in activities of daily living even 6 months after total knee arthroplasty (TKA). Moderate-quality evidence exists for several sociodemographic and clinical predictors of patient-reported outcome measures of perceived functionality. Objectively measured performance-based measures (PBMs) provide a less subjective approach to informing patient treatment after TKA; however, there is a dearth of information on predictors of functionally relevant PBMs...
October 17, 2018: Physical Therapy
Narut Prasitlumkum, Chanavuth Kanitsoraphan, Veraprapas Kittipibul, Pattara Rattanawong, Pakawat Chongsathidkiet, Wisit Cheungpasitporn
INTRODUCTION: Atrial fibrillation (AF) is the most common arrhythmia, independently associated with significant mortality and morbidity. Recent studies suggest that AF is potentially associated with contrast-induced nephropathy (CIN) in patients with Coronary artery disease (CAD) undergoing catheterization. However, the association was not conclusive. Thus, we assessed the association between AF in patients with CAD and CIN by a systematic review of the literature and a meta-analysis...
October 17, 2018: Clinical Cardiology
Saima Naz, Rafiq Ahmad Khan, Jeevan Giddaluru, Srikanth Battu, Sandeep Kumar Vishwakarma, Mabu Subahan, Vishnupriya Satti, Nooruddin Khan, Aleem Ahmed Khan
Ulcerative colitis (UC) is a persistent inflammatory illness, which is clinically categorised as Inflammatory bowel disease (IBD), affecting millions of people worldwide. The precise cause behind the pathology of the disease remains unknown. However, the involvement of multiple factors including genetic predisposition, immunological deregulations, microbiota imbalance, and environmental triggers has been suggested. Amongst all these factors, the over-active immunological response reported in UC patients seems to be a promising target for therapy...
September 21, 2018: Cellular Immunology
Leonora Vllasaliu, Katrin Jensen, Matthias Dose, Ulrich Hagenah, Helmut Hollmann, Inge Kamp-Becker, Claus Lechmann, Louise Poustka, Judith Sinzig, Ingo Spitzcok von Brisinski, Ludger Tebartz van Elst, Diana Will, Kai Vogeley, Christine M Freitag
The diagnostics of autism spectrum disorder in children, adolescents and adults: Overview of the key questions and main results of the first part of the clinical S3-guideline Abstract. BACKGROUND: Autism spectrum disorders (ASD) include ICD-10 diagnoses of childhood autism, Asperger syndrome, and atypical autism; there is a lifetime prevalence of ~1 %. The aim of the evidence-based clinical guideline (AWMF-S3-Guideline) is to summarize the current evidence concerning diagnostic and therapeutic processes for professionals working in healthcare and social welfare and to provide consensus on clinical recommendations...
October 17, 2018: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
Roberta Elisa Rossi, Clorinda Ciafardini, Valentina Sciola, Dario Conte, Sara Massironi
OBJECTIVES: Little is known about chromogranin A (CgA) during follow-up of gastroenteropancreatic neuroendocrine neoplasms. We hypothesized that serial CgA monitoring might be useful for the assessment of tumor progression, and we performed a systematic review of the literature and meta-analysis. METHODS: A bibliographical search was performed in PubMed using "chromogranin A" and "neuroendocrine tumors" and "follow-up" and "biomarker" to identify all pertinent articles published in the last 10 years...
November 2018: Pancreas
T Vanbrabant, M Fassnacht, G Assle, O M Dekkers
OBJECTIVE: Adrenocortical carcinoma (ACC) is a malignancy with a poor prognosis. Many publications in ACC report on risk factors for a poor outcome; one risk factor studied is hormonal hypersecretion (cortisol, sex-hormones, steroid precursors or aldosterone). The aim of this systematic review was to study the association between hormonal secretion and recurrence or mortality in ACC. DESIGN: Systematic review and meta-analysis. We searched PubMed, EMBASE and The Cochrane library (January 2018) for cohort studies examining the association between hormonal secretion on overall or recurrence-free survival in ACC...
October 1, 2018: European Journal of Endocrinology
Stefano Franchini, Luca Scarallo, Michele Carlucci, Luca Cabrini, Moreno Tresoldi
The purpose of the study was to assess the prognostic performances, in terms of in-hospital mortality, of the quick sequential organ failure assessment (qSOFA) score and the systemic inflammatory response syndrome (SIRS) criteria applied to patients with suspected infection outside the ICU, and to critically reappraise the results and the clinical impact of the SEPSIS-3 study and of the subsequent trials. We performed bivariate meta-analysis, evaluation of the Bayesian post-test probabilities of death, and computation of the unidentified deaths for every 1000 screened cases (UDS1000 )...
October 15, 2018: Internal and Emergency Medicine
Ebrahim Shakiba, Mazaher Ramezani, Masoud Sadeghi
Aim of the study: This meta-analysis evaluated serum interleukin-6 (IL-6) levels in hepatocellular carcinoma (HCC) patients compared with healthy controls and hepatitis and cirrhotic patients. Material and methods: The three databases PubMed, Scopus, and Web of Science were searched for assessment of IL-6 levels in HCC patients (without cirrhosis and hepatitis) compared with healthy controls (without HCC, cirrhosis and hepatitis) and the studies were selected based on inclusion and exclusion criteria...
September 2018: Clinical and Experimental Hepatology
Andrea Casadei Gardini, Giorgia Marisi, Matteo Canale, Francesco Giuseppe Foschi, Gabriele Donati, Giorgio Ercolani, Martina Valgiusti, Alessandro Passardi, Giovanni Luca Frassineti, Emanuela Scarpi
Background and aims: So far, no randomized trial or meta-analysis has been conducted on overall survival (OS) and recurrence-free survival (RFS) factors in patients treated with radiofrequency ablation (RFA) alone. The purpose of this meta-analysis was to evaluate prognostic factors of OS and RFS in patients treated with RFA. Methods: A primary analysis was planned to evaluate the clinical prognostic factor of OS. RFS was the secondary aim. Thirty-four studies published from 2003 to 2017 were analyzed...
2018: OncoTargets and Therapy
Jing Quan, Xiang Pan, Liwen Zhao, Zuwei Li, Kangfu Dai, Fangli Yan, Suyue Liu, Hongfei Ma, Yongqing Lai
Background: Bladder cancer is one of the most common urinary malignancies, and has a high recurrence rate and poor outcomes. In order to identify novel diagnostic and prognostic biomarkers for bladder cancer, we conducted a meta-analysis to analyze the association between long non-coding RNA (lncRNA) expression and survival in bladder cancer. Materials and methods: We searched literature from databases using our inclusion and exclusion criteria. STATA 14.0 software was used to analyze the data from collected studies and to construct the forest plots...
2018: OncoTargets and Therapy
(no author information available yet)
BACKGROUND: A body of empirical work demonstrates that wide fluctuations in a person's blood pressure across consecutive measures, known as blood pressure variability (BPV), hold prognostic value to predict stroke and transient ischemic attack. However, the magnitude of association between BPV and other neurological outcomes remains less clear. This systematic review aims to pool together data regarding BPV with respect to incident dementia, cognitive impairment, and cognitive function...
October 15, 2018: Systematic Reviews
M R S Siddiqui, C Simillis, J Bhoday, N J Battersby, J Mok, S Rasheed, P Tekkis, A M Abulafi, G Brown
AIM: Although T3 tumour subclassifications have been linked to prognosis, its mandatory adoption in histopathological reports has not been incorporated. This article focusses on the survival outcomes in patients with T3 rectal cancer according to extramural spread beyond the muscularis propria. METHODS: A systematic review of all studies up to January 2016, without language restriction, was identified from MEDLINE, Cochrane Controlled Trials Register (1960-2016) and Embase (1991-2016)...
October 12, 2018: European Journal of Cancer
Abigail Moore, Anthony Harnden, Cameron C Grant, Sheena Patel, Richard S Irwin
BACKGROUND: The decision to treat a suspected case of pertussis with antibiotics is usually based on a clinical diagnosis rather than waiting for laboratory confirmation. The current guideline focuses on making the clinical diagnosis of pertussis-associated cough in adults and children. METHODS: The American College of Chest Physicians (CHEST) methodologic guidelines and the Grading of Recommendations, Assessment, Development, and Evaluation framework were used...
October 12, 2018: Chest
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"