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diagnostic or prognostic meta analysis

Seong-Jang Kim, Sang-Woo Lee, Shin Young Jeong, Kyoungjune Pak, Keunyoung Kim
The purpose of the current study was to investigate the diagnostic performance of F-18 Fluorocholine (FCH) positron emission tomography/computed tomography (PET/CT) for localization of hyperfunctioning parathyroid gland in patients with hyperparathyroidism (HPT) through a systematic review and meta-analysis. The MEDLINE/PubMed and EMBASE database, from the earliest available date of indexing through April 30, 2018, were searched for studies evaluating the diagnostic performance of F-18 FCH PET/CT for localization of hyperfunctioning parathyroid gland in patients with HPT...
August 18, 2018: Hormones & Cancer
Yanlin Yin, Xinwei Liu, Xinming Yang, Jie Guo, Qiang Wang, Lixing Chen
BACKGROUND: Spondylitis is a rare infection in bone requiring multiple diagnostic strategies for verification. PURPOSE: This study aimed to compare the diagnostic values of 18 F-fluorodeoxyglucose positron emission tomography (FDG-PET) and magnetic resonance imaging (MRI) in detecting spondylitis. METHODS: Online PubMed, Embase, and Cochrane Library databases were systematically searched through September 2017 for studies comparing the diagnostic values of 18 F-FDG-PET and MRI...
August 16, 2018: Spine Journal: Official Journal of the North American Spine Society
Xionghu Shen, Longzhen Piao, Songnan Zhang, Yan Cui, Yuzhen Cui, Xianglan Quan, Honghua Sun
BACKGROUND: Recently, long noncoding RNA activated by transforming growth factor beta (TGF-β) (lncRNA ATB) was shown be useful in cancer prognosis, however, its prognostic value in human cancer has been inconsistent. Our study aimed to explore the prognostic role of lncRNA ATB expression in cancer prognosis. METHODS: PubMed, Embase, and the Cochrane Library databases were thoroughly searched to retrieve studies focusing on the prognostic role of lncRNA ATB expression in cancer, and meta-analysis was performed...
August 16, 2018: International Journal of Surgery
Sang-Woo Lee, Seong-Jang Kim, Youngduk Seo, Shin Young Jeong, Byeong-Cheol Ahn, Jaetae Lee
BACKGROUND: The aim of this study is to investigate the performance of F-18 fluorodeoxyglucose positron emission tomography (F-18 FDG PET) or positron emission tomography/computed tomography (PET/CT) for the assessment of disease activity in patients with large vessel vasculitis (LVV) through a meta-analysis. METHODS: The MEDLINE via PubMed and EMBASE were searched for the studies evaluating the performance of F-18 FDG PET or PET/CT in the assessment of disease activity in patients with LVV...
August 17, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Michael Gottlieb, Dallas Holladay, Gary D Peksa
STUDY OBJECTIVE: Intubation is routinely performed in the emergency department, and rapid, accurate confirmation is essential to avoid potentially serious adverse outcomes. The number of studies assessing ultrasonography for the verification of endotracheal tube placement has expanded rapidly in recent years. We performed this systematic review and meta-analysis to determine the sensitivity and specificity of transtracheal ultrasonography for the verification of endotracheal tube location...
August 14, 2018: Annals of Emergency Medicine
Qiang Zhang, Zhijiang Qi, Bo Liu, Chunsheng Li
This study was aimed at a serial evaluation of the prognostic values of initial shockable rhythm, bystander cardiopulmonary resuscitation (CPR) and gender for neurological outcome and survival in adults treated with targeted temperature management (TTM) following cardiac arrest (CA). PubMed, Embase and the Cochrane Library were searched for eligible studies. Pooled odds ratio (OR) with 95% confidence intervals (CIs) was calculated to evaluate prognostic values using RevMan 5.3. The outcomes were favorable neurological outcome (defined as cerebral performance category of 1 and 2) and survival...
August 14, 2018: Heart & Lung: the Journal of Critical Care
Tracy L Leong, Paula M Loveland, Alexandra Gorelik, Louis Irving, Daniel P Steinfort
BACKGROUND: Performance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for staging the radiologically normal mediastinum has been reported with inconsistent findings. We assessed the sensitivity of systematic staging using EBUS-TBNA for detection of radiologically occult mediastinal metastases in cN0/N1 lung cancer. METHODS: Studies evaluating EBUS-TBNA for systematic mediastinal staging in cN0/N1 lung cancer were identified by systematic review...
August 16, 2018: Journal of Bronchology & Interventional Pulmonology
Dong Wook Kim, Hee Mang Yoon, Ah Young Jung, Jin Seong Lee, Seak Hee Oh, Kyung Mo Kim, Young Ah Cho
OBJECTIVES: To assess the diagnostic performance of ultrasound (US) elastography in evaluating portal hypertension in children and compare the liver and spleen stiffness values between the portal hypertension and control groups. METHODS: Studies in the MEDLINE and Embase databases were selected that investigated the diagnostic performance of US elastography in children with portal hypertension up to December 21, 2017. Pooled sensitivity and specificity data were assessed by hierarchical logistic regression modeling...
August 16, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Rishad Khan, Joanne Plahouras, Bradley C Johnston, Michael A Scaffidi, Samir C Grover, Catharine M Walsh
BACKGROUND: Endoscopy has traditionally been taught with novices practicing on real patients under the supervision of experienced endoscopists. Recently, the growing awareness of the need for patient safety has brought simulation training to the forefront. Simulation training can provide trainees with the chance to practice their skills in a learner-centred, risk-free environment. It is important to ensure that skills gained through simulation positively transfer to the clinical environment...
August 17, 2018: Cochrane Database of Systematic Reviews
Jamal Hallajzadeh, Maliheh Khoramdad, Nahid Karamzad, Amir Almasi-Hashiani, Ali Janati, Erfan Ayubi, Reza Pakzad, Mark J M Sullman, Saeid Safiri
Introduction: The objectives of this study were to provide an estimate of the prevalence of metabolic syndrome (MetS ) and its components among women with PCOS; and calculate the odds ratio (OR) for MetS (using different definitions of MetS) in women with PCOS, compared to healthy controls. Methods: All of the relevant databases were used to search for appropriate articles that were published during the period 2003-2016. We included observational studies (cross-sectional, comparative cross-sectional) among women who met the inclusion criteria...
2018: Journal of Cardiovascular and Thoracic Research
C H Suh, H S Kim, S C Jung, C G Choi, S J Kim
BACKGROUND: Accurate diagnosis of tumefactive demyelinating lesions is clinically important to avoid unnecessary invasive biopsy or inappropriate treatment. PURPOSE: We aimed to evaluate conventional and advanced MR imaging findings of tumefactive demyelinating lesions and determine the diagnostic performance of MR imaging for differentiating tumefactive demyelinating lesions from primary brain tumor. DATA SOURCES: A systematic search of Ovid MEDLINE and EMBASE up to December 6, 2017, was conducted...
August 16, 2018: AJNR. American Journal of Neuroradiology
Cécile Tromeur, Liselotte M van der Pol, Pierre-Yves Le Roux, Yvonne Ende-Verhaar, Pierre-Yves Salaun, Christophe Leroyer, Francis Couturaud, Lucia J M Kroft, Menno V Huisman, Frederikus A Klok
Differences of computed tomography pulmonary angiography versus ventilation-perfusion lung scan in pregnant patients with suspected acute pulmonary embolism are not well-known, leading to ongoing debate on which test to choose. We searched in PUBMED, EMBASE, Web of science and Cochrane library databases and identified all relevant articles and abstracts published up to October1st 2017. We assessed diagnostic efficiency, frequency of non-diagnostic results and radiation exposure for patient and fetus. We included 13 studies for the diagnostic efficiency analysis, 30 for non-diagnostic results analysis and 22 for radiation exposure analysis...
August 16, 2018: Haematologica
Neil A J Ryan, Dominic Blake, Marcus Cabrera-Dandy, Mark A Glaire, D Gareth Evans, Emma J Crosbie
BACKGROUND: Lynch syndrome is the most common inherited cancer syndrome, which predisposes individuals to a number of different cancers, principally colorectal and endometrial cancer. The early diagnosis of Lynch syndrome enables colorectal surveillance, which has been shown to save lives through the detection and removal of premalignant polyps and earlier detection of invasive disease. Endometrial cancer, which is often the sentinel cancer in women, provides an opportunity to diagnose Lynch syndrome and thus enable colorectal surveillance as well as the cascade testing for Lynch syndrome in other family members...
August 16, 2018: Systematic Reviews
Shefaly Shorey, Cornelia Yin Ing Chee, Esperanza Debby Ng, Yiong Huak Chan, Wilson Wai San Tam, Yap Seng Chong
This review aims to examine the prevalence and incidence of postpartum depression among healthy mothers without prior history of depression including postpartum depression and who gave birth to healthy full-term infants. A systematic search of, CINAHL, EMBASE, PsycINFO, and PubMed was performed for English articles from the inception of the database to November 2017, as well as a manual search of the reference lists of the included articles, and an expert panel was consulted. Across 15,895 articles, 58 articles (N = 37,294 women) were included in the review...
August 3, 2018: Journal of Psychiatric Research
Yuan Cheng, Manni Wang, Buyun Ma, Xuelei Ma
BACKGROUND: The purpose of this study was to systematically review and evaluate the diagnostic accuracy of contrast-enhanced ultrasound (CEUS) in differentiating malignant and benign gallbladder lesions. METHODS: We conducted a comprehensive search on PubMed, Embase, and Cochrane Library for all potential relevant articles published before December 2017. The pooled sensitivity, specificity, diagnostic odds ratio (DOR) and area under the curve (AUC) of summary receiver operating characteristic (SROC) were calculated by Meta-Disc Version 1...
August 2018: Medicine (Baltimore)
Shuai Qie, Yanhong Li, Hong-Yun Shi, Lanhui Yuan, Lei Su, Xi Zhang
BACKGROUND: The present study aims to assess the therapeutic effect of whole brain radiotherapy (WBRT) for brain metastases from non-small cell lung cancer stratified by graded prognostic assessment (GPA) through meta-analysis. METHODS: The Cochrane Library, PubMed, Ovid (Elsevier) were retrieved. The included randomized controlled trials (RCT) were evaluated, and the statistical analysis was performed using RevMan 5.3 software. Cochrane handbook was applied to evaluate the methodological quality...
August 2018: Medicine (Baltimore)
Marie Reisener, Carsten Perka
Background: Culture-negative periprosthetic joint infections (CN PJI) have not been well studied, and due to the lack of consensus on PJI, especially with culture-negative infections, there are considerable uncertainties. Due to the challenging clinical issue of CN PJI the aim of this systematic review is to describe incidence, diagnosis, and treatment outcomes based on the current literature on CN PJI. Hypothesis: The review is designed to assess the formal hypothesis that CN PJI of the hip and knee have a poorer outcome when compared with culture-positive ones...
2018: BioMed Research International
Getinet Ayano, Melat Solomon, Mebratu Abraha
BACKGROUND: Depression is the most prevalent psychiatric disorder among people living with HIV (PLWHIV) and is associated with poor quality of life, additional comorbidities, disability, unemployment, poorer therapeutic outcomes and risky behaviors. The present systematic review and meta-analysis aims to systematically summarize empirical evidence and to formulate recommendations for future research. METHODS: We searched PubMed, EMBASE, SCOPUS, and relevant literature for possible studies to include...
August 15, 2018: BMC Psychiatry
Hoang Thi Nam Giang, Keita Banno, Le Huu Nhat Minh, Lam Tuyet Trinh, Le Thai Loc, Asmaa Eltobgy, Luu Lam Thang Tai, Adnan Khan, Nguyen Hoang Tuan, Yaser Reda, Maryan Samsom, Nguyen Tran Nam, Nguyen Tien Huy, Kenji Hirayama
We systematically searched and meta-analyzed the epidemiological characteristics, frequency of clinical signs, and outcomes of dengue-associated hemophagocytic lymphohistiocytosis. Ten electronic databases were searched systematically plus manual search of reference lists to identify relevant articles published until May 2017. The highest number of reported cases were from South-East Asia region (62 cases), followed by Western Pacific region (20 cases), and America (31 cases). The term "dengue hemorrhagic fever" predominated in studies that used the World Health Organization 1997 definition (59...
August 15, 2018: Reviews in Medical Virology
Sarah Z Wennmacker, Mark P Lamberts, Marcello Di Martino, Joost Ph Drenth, Kurinchi Selvan Gurusamy, Cornelis Jhm van Laarhoven
BACKGROUND: Approximately 0.6% to 4% of cholecystectomies are performed because of gallbladder polyps. The decision to perform cholecystectomy is based on presence of gallbladder polyp(s) on transabdominal ultrasound (TAUS) or endoscopic ultrasound (EUS), or both. These polyps are currently considered for surgery if they grow more than 1 cm. However, non-neoplastic polyps (pseudo polyps) do not need surgery, even when they are larger than 1 cm. True polyps are neoplastic, either benign (adenomas) or (pre)malignant (dysplastic polyps/carcinomas)...
August 15, 2018: Cochrane Database of Systematic Reviews
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