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https://www.readbyqxmd.com/read/27136094/neurovascular-coupling-in-patients-with-relapsing-remitting-multiple-sclerosis
#1
Gulnur Tekgöl Uzuner, Nevzat Uzuner
OBJECTIVES: Also to the inflammatory demyelinating lesions and degenerative process, altered cerebrovascular reactivity or neurovascular coupling (NVC) might be considered as playing another role in the pathogenesis of multiple sclerosis. The objective of this study is to assess the NVC of patients with relapsing-remitting multiple sclerosis (RRMS) during the acute exacerbation period. PATIENTS AND METHODS: Four hundred fifty-eight patients with RRMS and 160 healthy subjects were screened for this study during the last 14 years...
July 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/25935890/predictors-for-being-offered-epilepsy-surgery-5-year-experience-of-a-tertiary-referral-centre
#2
Chiara Fois, Stjepana Kovac, Aytakin Khalil, Gülnur Tekgöl Uzuner, Beate Diehl, Tim Wehner, John S Duncan, Matthew C Walker
OBJECTIVES: To define factors that predict whether patients with pharmacoresistant focal epilepsy are offered epilepsy surgery (including invasive EEG) and the main reasons for not proceeding with these after non-invasive presurgical evaluation. METHODS: We retrospectively analysed data from 612 consecutive patients with focal epilepsy admitted to a video-EEG Telemetry Unit for presurgical evaluation, and used a multivariate logistic regression model to assess the predictive value of factors for being offered potentially curative surgery...
February 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/23984332/relationship-between-pulsatility-index-and-clinical-course-of-acute-ischemic-stroke-after-thrombolytic-treatment
#3
Nevzat Uzuner, Özcan Özdemir, Gülnur Tekgöl Uzuner
Background. The relationship between the arterial recanalization after intravenous recombinant tissue plasminogen activator (rtPA) and outcomes is still uncertain. The aim of our study was to evaluate whether there is an association between the pulsatility indexes (PI) of the middle cerebral artery (MCA) measured by transcranial Doppler (TCD) after iv rtPA treatment and short- and long-term outcomes in ischemic stroke patients. Methods. Forty-eight patients with acute ischemia in the MCA territory who achieved complete recanalization after the administration of intravenous thrombolytic treatment were included in the study...
2013: BioMed Research International
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