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https://www.readbyqxmd.com/read/28101829/autism-spectrum-disorders%C3%A2-diagnosis-and-management
#1
REVIEW
Sharmila Banerjee Mukherjee
Autism Spectrum Disorder (ASD) is a neuro-developmental disorder commonly seen in children. It is characterized by age inappropriate, impaired social communication and the presence of stereotypic behavior. This disorder is hypothesized to result from cerebral dysfunction arising from a complex interaction between genetic, epigenetic and environmental factors. ASD should be suspected in children failing ASD specific screening tests, in the presence of red flags in social, language and/or play domains, in children with developmental or language delay, abnormal behavior, poor school performance or in those who are at high risk...
January 19, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28075699/outcome-and-impact-evaluation-of-a-transgender-health-course-for-health-profession-students
#2
Hannan M Braun, Ilana R Garcia-Grossman, Andrea Quiñones-Rivera, Madeline B Deutsch
PURPOSE: Being transgender is associated with numerous health disparities, and transgender individuals face mistreatment and discrimination in healthcare settings. At the same time, healthcare professionals report inadequate preparation to care for transgender people, and patients often have to teach their own medical providers about transgender care. Our study aimed to evaluate the impact of an elective course for health profession students in transgender health that was implemented to address these gaps in provider knowledge...
January 11, 2017: LGBT Health
https://www.readbyqxmd.com/read/28051830/gambling-and-the-need-for-new-responses-in-public-health-with-an-addiction-sine-substantia
#3
M Crusco, F Massoni, E Luzi, P Ricci, M Pelosi, P Corbosiero, M Rapp-Ricciardi, S Ricci
BACKGROUND: The Gambling Disorder (GD) was recently defined as a behavioral addiction by the "The Diagnostic and Statistical Manual of Mental Disorders IV"( DSM-V) since the clinical, neurobiological and psychopathological similarities led it to be defined it as an addiction "sine substantia". The aim of this study is to formulate an "identikit" of the gambler, to evaluate a possible association between GD / emotional specific factors and the correlation between GD / substance abuse, GD / suicide...
November 2016: La Clinica Terapeutica
https://www.readbyqxmd.com/read/28040410/a-genome-wide-association-study-of-fast-beta-eeg-in-families-of-european-ancestry
#4
Jacquelyn L Meyers, Jian Zhang, Niklas Manz, Madhavi Rangaswamy, Chella Kamarajan, Leah Wetherill, David B Chorlian, Sun J Kang, Lance Bauer, Victor Hesselbrock, John Kramer, Samuel Kuperman, John I Nurnberger, Jay Tischfield, Jen Chyong Wang, Howard J Edenberg, Alison Goate, Tatiana Foroud, Bernice Porjesz
BACKGROUND: Differences in fast beta (20-28 Hz) electroencephalogram (EEG) oscillatory activity distinguish some individuals with psychiatric and substance use disorders, suggesting that it may be a useful endophenotype for studying the genetics of disorders characterized by neural hyper-excitability. Despite the high heritability estimates provided by twin and family studies, there have been relatively few genetic studies of beta EEG, and to date only one genetic association finding has replicated (i...
December 28, 2016: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/27915219/dynamic-thiol-disulfide-homeostasis-in-children-with-attention-deficit-hyperactivity-disorder-and-its-relation-with-disease-subtypes
#5
Sibelnur Avcil, Pınar Uysal, Mucahit Avcil, Murat Alışık, Cemile Biçer
BACKGROUND: The aim of this study was to evaluate a novel oxidative stress marker (thiol/disulfide homeostasis) in attention deficit hyperactivity disorder (ADHD) children for the first time in literature. METHODS: Ninety children with ADHD diagnosed according to DSM-V and as control group, 65 healthy children were included to the study. Native thiol, total thiol, disulfide, disulfide/native thiol, disulfide/total thiol were compared between the groups. RESULTS: Total and native thiol levels were significantly higher whereas the disulfide/native thiol ratios were significantly lower in children with ADHD...
November 13, 2016: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/27886010/discriminative-properties-of-hippocampal-hypoperfusion-in-marijuana-users-compared-to-healthy-controls-implications%C3%A2-for-marijuana-administration%C3%A2-in%C3%A2-alzheimer-s-dementia
#6
Daniel G Amen, Borhan Darmal, Cyrus A Raji, Weining Bao, Lantie Jorandby, Somayeh Meysami, Cauligi S Raghavendra
BACKGROUND: Few studies have evaluated the impact of marijuana use on regional cerebral blood flow. OBJECTIVE: To determine whether perfusion in specific brain regions on functional neuroimaging, including those affected by Alzheimer's disease pathology, are abnormal in marijuana users compared to controls. METHOD: Persons with a diagnosis of cannabis use disorder by DSM-IV and DSM-V criteria (n = 982) were compared to controls (n = 92) with perfusion neuroimaging with SPECT at rest and at a concentration task...
November 24, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27862704/what-happens-to-children-who-move-off-the-autism-spectrum-a-clinical-follow-up-study
#7
Nahit Motavalli Mukaddes, Tuba Mutluer, Basak Ayik, Ayla Umut
OBJECTIVES: There is controversial information on school age outcome of individuals who lose the diagnosis of autism and achieve "optimal outcome" (OO). The present study aimed to assess the autism symptoms and other psychiatric disorders in a group of children with a past history of autism. METHODS: The study includes individuals (n=26) who lost the diagnosis of autism two to eight years previously. Clinical assessment was done with both parents and children. DSM-V criteria were used for diagnosis of ASD...
November 12, 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27859868/preferences-of-psychiatric-practitioners-for-core-symptoms-of-major-depressive-disorder-a-hidden-conjoint-analysis
#8
Matthias W Riepe, Peter Gritzmann, Andreas Brieden
According to ICD-10 and DSM-V, symptoms of depressive disorder are considered to be equally important for severity judgment. It was the goal to investigate the weight of selected symptom complexes for severity judgment. In workaday life severity judgment results from an overall impression rather than from calculating severity in different symptom complexes, separately. In fact, the drivers for overall judgment may not be known explicitly to the psychiatrist himself. A method of choice to resolve this is conjoint analysis...
November 9, 2016: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/27826070/research-domain-criteria-versus-dsm-v-how-does-this-debate-affect-attempts-to-model-corticostriatal-dysfunction-in-animals
#9
REVIEW
Jared W Young, Catharine A Winstanley, Anne Marie Brady, Frank Scott Hall
For decades, the nosology of mental illness has been based largely upon the descriptions in the Diagnostic and Statistical Manual of the American Psychiatric Association (DSM). A recent challenge to the DSM approach to psychiatric nosology from the National Institute on Mental Health (USA) defines Research Domain Criteria (RDoC) as an alternative. For RDoC, psychiatric illnesses are not defined as discrete categories, but instead as specific behavioral dysfunctions irrespective of DSM diagnostic categories...
November 5, 2016: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27821114/bright-light-therapy-in-pregnant-women-with-major-depressive-disorder-study-protocol-for-a-randomized-double-blind-controlled-clinical-trial
#10
Babette Bais, Astrid M Kamperman, Marjolein D van der Zwaag, Gwen C Dieleman, Hanneke W Harmsen van der Vliet-Torij, Hilmar H Bijma, Ritsaert Lieverse, Witte J G Hoogendijk, Mijke P Lambregtse-van den Berg
BACKGROUND: Depression during pregnancy is a common and high impact disease. Generally, 5-10 % of pregnant women suffer from depression. Children who have been exposed to maternal depression during pregnancy have a higher risk of adverse birth outcomes and more often show cognitive, emotional and behavioural problems. Therefore, early detection and treatment of antepartum depression is necessary. Both psychotherapy and antidepressant medication, first choice treatments in a non-pregnant population, have limitations in treating depression during pregnancy...
November 8, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27816188/delirium-in-patients-with-acute-ischemic-stroke-admitted-to-the-non-intensive-stroke-unit-incidence-and-association-between-clinical-features-and-inflammatory-markers
#11
Hasan Hüseyin Kozak, Faruk Uğuz, İbrahim Kılınç, Ali Ulvi Uca, Osman Serhat Tokgöz, Zehra Akpınar, Nejla Özer
BACKGROUND: Stroke patients with development of delirium have unfavorable outcomes, higher mortality, longer hospitalizations, and a greater degree of dependence after discharge. Studies suggest that delirium is associated with abnormal immunological responses and a resultant increase in inflammatory markers. OBJECTIVE: Our aim was to determine whether there is an entity relationship between delirium, inflammation and acute ischemic stroke (AIS). METHODS: Sixty AIS patients admitted to the hospital were consecutively recruited...
October 24, 2016: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/27809351/effect-of-memantine-combination-therapy-on-symptoms-in-patients-with-moderate-to-severe-depressive-disorder-randomized-double-blind-placebo-controlled-study
#12
M Amidfar, M Khiabany, A Kohi, E Salardini, M Arbabi, M Roohi Azizi, M-R Zarrindast, P Mohammadinejad, A Zeinoddini, S Akhondzadeh
WHAT IS KNOWN AND OBJECTIVE: Current treatments for depressive disorders are far from optimum. This study was planned to evaluate possible antidepressant effects and safety of memantine, a selective N-methyl-d-aspartate receptor antagonist, in humans. METHODS: Sixty-six outpatients with the diagnosis of moderate-to-severe major depressive disorder, based on DSM-V diagnostic criteria, were recruited to participate in a parallel, randomized, controlled trial. Sixty-two participants completed 6 weeks of treatment with either memantine (20 mg/day) plus sertraline (200 mg/day) or placebo plus sertraline (200 mg/day)...
February 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/27804994/associations-between-adverse-childhood-experiences-and-clinical-characteristics-of-eating-disorders
#13
S Guillaume, I Jaussent, L Maimoun, A Ryst, M Seneque, L Villain, D Hamroun, P Lefebvre, E Renard, Ph Courtet
Patients with eating disorders (EDs) frequently report a history of childhood trauma (CT). We investigated whether certain subtypes of CT are associated with more severe features of EDs, independently of psychiatric comorbidity, and whether they act additively. One hundred and ninety-two patients with DSM-V-defined EDs were consecutively recruited. Five clinical characteristics were assessed: restraint, eating, shape and weight concerns on the EDE-Q, and daily functioning. CT was assessed by the childhood traumatism questionnaire...
November 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27751561/assessing-motor-proficiency-in-young-adults-the-bruininks-oseretsky-test-2-short-form-and-the-mccarron-assessment-of-neuromuscular-development
#14
F McIntyre, H Parker, A Thornton, M Licari, J Piek, D Rigoli, B Hands
Currently, only two motor tests have norms extending into young adulthood - the McCarron Assessment of Neuromuscular Development (MAND, McCarron 1997) and the Bruininks Oseretsky Test of Motor Proficiency-2 (BOT-2, Bruininks & Bruininks, 2005). Research into the motor difficulties in early adulthood and health outcomes has been impeded because there is no agreed gold standard motor test for this group. The purposes of this study were to compare the discrimination accuracy, classification agreement, and predictive values, and gender distribution and prevalence of each test in identifying motor impairment (MI) in relation to DSM-V diagnostic criteria for DCD...
October 14, 2016: Human Movement Science
https://www.readbyqxmd.com/read/27723545/spontaneous-neural-activity-in-the-right-superior-temporal-gyrus-and-left-middle-temporal-gyrus-is-associated-with-insight-level-in-obsessive-compulsive-disorder
#15
Jie Fan, Mingtian Zhong, Jun Gan, Wanting Liu, Chaoyang Niu, Haiyan Liao, Hongchun Zhang, Changlian Tan, Jinyao Yi, Xiongzhao Zhu
BACKGROUND: Insight into illness is an important issue for psychiatry disorder. Although the existence of a poor insight subtype of obsessive-compulsive disorder (OCD) was recognized in the DSM-IV, and the insight level in OCD was specified further in DSM-V, the neural underpinnings of insight in OCD have been rarely explored. The present study was designed to bridge this research gap by using resting-state functional magnetic resonance imaging (fMRI). METHODS: Spontaneous neural activity were examined in 19 OCD patients with good insight (OCD-GI), 18 OCD patients with poor insight (OCD-PI), and 25 healthy controls (HC) by analyzing the amplitude of low-frequency fluctuation (ALFF) in the resting state...
October 2, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27693465/corrigendum-to-bereavement-related-depression-did-the-changes-induced-by-dsm-v-make-a-difference-results-from-a-large-population-based-survey-of-french-residents-j-affect-disord-182-2015-82-90
#16
Florence Clesse, Emmanuelle Leray, Florence Bodeau-Livinec, Mathilde Husky, Viviane Kovess-Masfety
No abstract text is available yet for this article.
September 28, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27671030/assessment-of-sexual-difficulties-associated-with-multi-modal-treatment-for-cervical-or-endometrial-cancer-a-systematic-review-of-measurement-instruments
#17
REVIEW
Isabella D White, Amrit Sangha, Grace Lucas, Theresa Wiseman
BACKGROUND: Practitioners and researchers require an outcome measure that accurately identifies the range of common treatment-induced changes in sexual function and well-being experienced by women after cervical or endometrial cancer. This systematic review critically appraised the measurement properties and clinical utility of instruments validated for the measurement of female sexual dysfunction (FSD) in this clinical population. METHODS: A bibliographic database search for questionnaire development or validation papers was completed and methodological quality and measurement properties of selected studies rated using the Consensus-based Standards for the selection of health Measurement Instrument (COSMIN) checklist...
December 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27645129/psychological-distress-in-jordanian-parents-of-children-with-autism-spectrum-disorder-the-role-of-trait-mindfulness
#18
Ahmad Rayan, Muayyad Ahmad
AIM: This study examines the role of mindfulness in predicting psychological distress in Arab parents of children with autism spectrum disorder (ASD). METHOD: In this descriptive study, parents of 104 children with ASD completed measures of psychological distress and mindfulness. The severity of autism in children was measured using the DSM-V criteria. RESULTS: After controlling for parental age and gender and the severity level of ASD, mindfulness was significantly associated with the levels of anxiety, stress, and depression in parents (anxiety: β = 0...
September 20, 2016: Perspectives in Psychiatric Care
https://www.readbyqxmd.com/read/27644917/-left-temporal-arachnoid-cyst-and-specific-learning-disorders-associated-with-pervasive-developmental-disorders-not-otherwise-specified-pdd-nos-contributions-of-an-integrative-neuropsychomotor-neuropsychological-psychopathological-and-neurosurgical-approach
#19
L Vaivre-Douret, A Boschi, M L Cuny, C Clouard, A Mosser, B Golse, A Philippe, M Bourgeois, N Boddaert, S Puget
: Left temporal arachnoid cyst and specific learning disorders associated with pervasive developmental disorders - not otherwise specified (PDD-NOS): contributions of an integrative neuro-psychomotor, neuropsychological, psychopathological and neurosurgical approach about a case report in a child (François). With DSM-IV and DSM-IV-TR, the terminology of pervasive developmental disorders (PDD) covers two main categories of infantile disorders: disorders of "strictly" autistic nature and pervasive developmental disorders - not otherwise specified (PDD-NOS)...
December 2016: L'Encéphale
https://www.readbyqxmd.com/read/27639419/the-prognostic-value-of-formal-thought-disorder-following-first-episode-psychosis
#20
Eric Roche, John Lyne, Brian O'Donoghue, Ricardo Segurado, Caragh Behan, Laoise Renwick, Felicity Fanning, Kevin Madigan, Mary Clarke
BACKGROUND: Formal thought disorder (FTD) is associated with poor outcome in established psychotic illnesses and it can be assessed as a categorical or dimensional variable. However, its influence on functional outcome and hospitalisation patterns in early psychosis has not been investigated. We evaluated the relationship between FTD and these outcomes in a first episode psychosis (FEP) sample. MATERIALS AND METHODS: A mixed diagnostic FEP cohort was recruited through an Early Intervention in Psychosis Service in Ireland...
December 2016: Schizophrenia Research
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