Jipeng Yan, Biao Huang, Johanna Tonko, Matthieu Toulemonde, Joseph Hansen-Shearer, Qingyuan Tan, Kai Riemer, Konstantinos Ntagiantas, Rasheda A Chowdhury, Pier D Lambiase, Roxy Senior, Meng-Xing Tang
Myocardial microvasculature and haemodynamics are indicative of potential microvascular diseases for patients with symptoms of coronary heart disease in the absence of obstructive coronary arteries. However, imaging microvascular structure and flow within the myocardium is challenging owing to the small size of the vessels and the constant movement of the patient's heart. Here we show the feasibility of transthoracic ultrasound localization microscopy for imaging myocardial microvasculature and haemodynamics in explanted pig hearts and in patients in vivo...
May 6, 2024: Nature Biomedical Engineering